Evidence that proline focuses movement of the floppy loop of arylalkylamine N-acetyltransferase (EC 2.3.1.87)

Journal of Biological Chemistry

Volumn 283, Issue 21, 2008, Pages 14552-14558

  Pavlicek, Jiri ^a   Coon, Steven L ^a   Ganguly, Surajit ^a,d   Weller, Joan L ^a   Hassan, Sergio A ^c   Sackett, Dan L ^b   Klein, David C ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d The Centre for Genomic Applications   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; PHOTOLITHOGRAPHY; RATE CONSTANTS; STRUCTURAL ANALYSIS;

BINDING POCKETS; BINDING STUDIES; DISSOCIATION CONSTANTS; HORMONAL SIGNALS; INTRAMOLECULAR INTERACTIONS; LANGEVIN DYNAMICS; LOCAL FLEXIBILITIES; MODEL SUBSTRATES; REDUCING ACTIVITIES; SYNTHESIS OF; TRI PEPTIDES;

HORMONES;

ARALKYLAMINE ACETYLTRANSFERASE; PROLINE; TRIPEPTIDE; GUANIDINE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENE EXPRESSION; GENETICS; METABOLISM; MUTATION; PROTEIN DENATURATION; PROTEIN TERTIARY STRUCTURE; SHEEP;

VERTEBRATA;

ANIMALS; ARYLALKYLAMINE N-ACETYLTRANSFERASE; GENE EXPRESSION; GUANIDINE; MODELS, MOLECULAR; MUTATION; PROLINE; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; SHEEP; SUBSTRATE SPECIFICITY;

EID: 47249152275     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800593200     Document Type: Article

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