Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma

Clinical Cancer Research

Volumn 19, Issue 8, 2013, Pages 1972-1980

  Hassan, Khaled A ^a   Wang, Luo ^a   Korkaya, Hasan ^a   Chen, Guoan ^b   Maillard, Ivan ^a   Beer, David G ^b   Kalemkerian, Gregory P ^a   Wicha, Max S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DOCETAXEL; GAMMA SECRETASE INHIBITOR; GREEN FLUORESCENT PROTEIN; MRK 003; NOTCH RECEPTOR; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER STEM CELL; CANCER SURVIVAL; CARCINOGENICITY; CONTROLLED STUDY; CORRELATIONAL STUDY; DRUG RESISTANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ADENOCARCINOMA; MONOTHERAPY; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL CYCLE; CELL LINE, TUMOR; CYCLIC S-OXIDES; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MICE; MICE, INBRED NOD; MICE, NUDE; MICE, SCID; MULTIVARIATE ANALYSIS; NEOPLASTIC STEM CELLS; PROTEIN ISOFORMS; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THIADIAZOLES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84877093512     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-12-0370     Document Type: Article

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