Induction of osteogenic differentiation of stem cells via a lyophilized microRNA reverse transfection formulation on a tissue culture plate

International Journal of Nanomedicine

Volumn 8, Issue , 2013, Pages 1595-1607

  Wu, Kaimin ^a   Xu, Jie ^a   Liu, Mengyuan ^a   Song, Wen ^a   Yan, Jun ^a   Gao, Shan ^b,c   Zhao, Lingzhou ^a   Zhang, Yumei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b AARHUS UNIVERSITY   (Denmark)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Lyophilization; Mesenchymal stem cells; microRNAs; Osteogenic differentiation; Tissue culture plate

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN; LIPOFECTAMINE; LIPOPLEX; MICRORNA;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; CYTOTOXICITY; DRUG FORMULATION; DRUG UPTAKE; FREEZE DRYING; GENE EXPRESSION; GENETIC TRANSFECTION; INTERMETHOD COMPARISON; MESENCHYMAL STEM CELL; MINERALIZATION; NONHUMAN; PROTEIN SYNTHESIS; RAT; REVERSE TRANSFECTION; STORAGE TEMPERATURE;

LYOPHILIZATION; MESENCHYMAL STEM CELLS; MICRORNAS; OSTEOGENIC DIFFERENTIATION; TISSUE CULTURE PLATE;

ALKALINE PHOSPHATASE; ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN; FREEZE DRYING; LIPIDS; MESENCHYMAL STROMAL CELLS; MICRORNAS; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION;

EID: 84877091149     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S43244     Document Type: Article

References (37)

1. Kota J, Chivukula RR, O'Donnell KA, et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 2009;137(6):1005-1017.
2. Alvarez-Garcia I, Miska EA. MicroRNA functions in animal development and human disease. Development. 2005;132(21):4653-4662.
3. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281-297.
4. Martignani E, Miretti S, Accornero P, Baratta M. miRNAs highlights in stem and cancer cells. Mini Rev Med Chem. 2011;11(13):1165-1182.
5. Kim YJ, Bae SW, Yu SS, Bae YC, Jung JS. miR-196a regulates proliferation and osteogenic differentiation in mesenchymal stem cells derived from human adipose tissue. J Bone Miner Res. 2009;24(5): 816-825.
6. Li H, Xie H, Liu W, et al. A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. J Clin Invest. 2009;119(12):3666-3677.
7. Eskildsen T, Taipaleenmaki H, Stenvang J, et al. MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo. Proc Natl Acad Sci U S A. 2011;108(15):6139-6144.
8. Schoolmeesters A, Eklund T, Leake D, et al. Functional profiling reveals critical role for miRNA in differentiation of human mesenchymal stem cells. PLoS One. 2009;4(5):e5605.
9. Tuddenham L, Wheeler G, Ntounia-Fousara S, et al. The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells. FEBS Lett. 2006;580(17):4214-4217.
10. Esau C, Kang X, Peralta E, et al. MicroRNA-143 regulates adipocyte differentiation. J Biol Chem. 2004;279(50):52361-52365.
11. Sun F, Wang J, Pan Q, et al. Characterization of function and regulation of miR-24-21 and miR-31. Biochem Biophys Res Commun. 2009; 380(3):660-665.
12. Chen JF, Mandel EM, Thomson JM, et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006;38(2):228-233.
13. Sun Q, Zhang Y, Yang G, et al. Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res. 2008;36(8):2690-2699.
14. Lim PK, Patel SA, Gregory LA, Rameshwar P. Neurogenesis: role for microRNAs and mesenchymal stem cells in pathological states. Curr Med Chem. 2010;17(20):2159-2167.
15. Yau WW, Rujitanaroj PO, Lam L, Chew SY. Directing stem cell fate by controlled RNA interference. Biomaterials. 2012;33(9):2608-2628.
16. Carthew RW, Sontheimer EJ. Origins and mechanisms of miRNAs and siRNAs. Cell. 2009;136(4):642-655.
17. Merdan T, Kopecek J, Kissel T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev. 2002; 54(5):715-758.
18. Elsabahy M, Nazarali A, Foldvari M. Non-viral nucleic acid delivery: key challenges and future directions. Curr Drug Deliv. 2011; 8(3):235-244.
19. Anchordoquy TJ, Koe GS. Physical stability of nonviral plasmid-based therapeutics. J Pharm Sci. 2000;89(3):289-296.
20. Ziauddin J, Sabatini DM. Microarrays of cells expressing defined cDNAs. Nature. 2001;411(6833):107-110.
21. Erfle H, Neumann B, Liebel U, et al. Reverse transfection on cell arrays for high content screening microscopy. Nat Protoc. 2007; 2(2):392-399.
22. Jewell CM, Lynn DM. Surface-mediated delivery of DNA: cationic polymers take charge. Curr Opin Colloid Interface Sci. 2008; 13(6):395-402.
23. Yadava P, Gibbs M, Castro C, Hughes JA. Effect of lyophilization and freeze-thawing on the stability of siRNA-liposome complexes. AAPS Pharm Sci Tech. 2008;9(2):335-341.
24. Allison SD, Molina MC, Anchordoquy TJ. Stabilization of lipid/DNA complexes during the freezing step of the lyophilization process: the particle isolation hypothesis. Biochim Biophys Acta. 2000; 1468(1-2):127-138.
25. Andersen MO, Howard KA, Paludan SR, Besenbacher F, Kjems J. Delivery of siRNA from lyophilized polymeric surfaces. Biomaterials. 2008;29(4):506-512.
26. Kundu AK, Chandra PK, Hazari S, et al. Stability of lyophilized siRNA nanosome formulations. Int J Pharm. 2012;423(2):525-534.
27. Andersen MO, Nygaard JV, Burns JS, et al. siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells. Mol Ther. 2010;18(11):2018-2027.
28. Reinisalo M, Urtti A, Honkakoski P. Freeze-drying of cationic polymer DNA complexes enables their long-term storage and reverse transfection of post-mitotic cells. J Control Release. 2006;110(2): 437-443.
29. Fujita S, Ota E, Sasaki C, Takano K, Miyake M, Miyake J. Highly efficient reverse transfection with siRNA in multiple wells of microtiter plates. J Biosci Bioeng. 2007;104(4):329-333.
30. Aguiari P, Leo S, Zavan B, et al. High glucose induces adipogenic differentiation of muscle-derived stem cells. Proc Natl Acad Sci U S A. 2008;105(4):1226-1231.
31. Escobedo J, Koh TJ. Improved transfection technique for adherent cells using a commercial lipid reagent. BioTechniques. 2003; 35(5):936-940.
32. Cheng ST, Chen ZF, Chen GQ. The expression of cross-linked elastin by rabbit blood vessel smooth muscle cells cultured in polyhydroxyalkanoate scaffolds. Biomaterials. 2008;29(31):4187-4194.
33. Luo D, Saltzman WM. Enhancement of transfection by physical concentration of DNA at the cell surface. Nat Biotechnol. 2000; 18(8):893-895.
34. Lv H, Zhang S, Wang B, Cui S, Yan J. Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release. 2006; 114(1):100-109.
35. Maitani Y, Aso Y, Yamada A, Yoshioka S. Effect of sugars on storage stability of lyophilized liposome/DNA complexes with high transfection efficiency. Int J Pharm. 2008;356(1-2):69-75.
36. Molina MC, Armstrong TK, Zhang Y, Patel MM, Lentz YK, Anchordoquy TJ. The stability of lyophilized lipid/DNA complexes during prolonged storage. J Pharm Sci. 2004;93(9):2259-2273.
37. Xu Y, Mirmalek-Sani SH, Lin F, Zhang J, Oreffo RO. Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells. RNA. 2007;13(8):1179-1183.