Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord

Journal of Controlled Release

Volumn 168, Issue 2, 2013, Pages 209-224

  Dengler, Ellen C ^a   Liu, Juewen ^b   Kerwin, Audra ^a   Torres, Sergio ^a   Olcott, Clara M ^a   Bowman, Brandi N ^a   Armijo, Leisha ^a   Gentry, Katherine ^a   Wilkerson, Jenny ^a   Wallace, James ^a   Jiang, Xingmao ^b   Carnes, Eric C ^b   Brinker, C Jeffrey ^b   Milligan, Erin D ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b MSC01 1070   (United States)

Author keywords

Biocompatibility; Cell and tissue viability; Gene delivery; Interleukin 10 cytokine; Neuropathic pain; Non viral vector

Indexed keywords

CYTOKINES; GENE DELIVERY; NEUROPATHIC PAIN; NONVIRAL VECTORS; TISSUE VIABILITY;

BIOCOMPATIBILITY; DRUG THERAPY; GENE TRANSFER; HEALTH; LIPID BILAYERS; LIPOSOMES; MOLECULAR BIOLOGY; SPACE PLATFORMS; TISSUE;

VECTOR SPACES;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; INTERLEUKIN 10;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID BILAYER; MALE; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; SPINAL CORD; SUBARACHNOID SPACE;

ANIMALS; ARTIFICIAL CELLS; CELL LINE; CELL SURVIVAL; CHOLESTEROL; DNA; FATTY ACIDS, MONOUNSATURATED; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HUMANS; INJECTIONS, SPINAL; INTERLEUKIN-10; LIPID BILAYERS; LIPOSOMES; MALE; MICE; NITRIC OXIDE; PHOSPHATIDYLCHOLINES; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SILICON DIOXIDE; SPINAL CORD;

EID: 84877066455     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.03.009     Document Type: Article

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