-
2
-
-
0038076054
-
X-ray structure of a voltage-dependent K + channel
-
Jiang Y, Lee A, Chen J, Ruta V, Cadene M, Chait BT, MacKinnon R (2003) X-ray structure of a voltage-dependent K + channel. Nature 423:33-41
-
(2003)
Nature
, vol.423
, pp. 33-41
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Ruta, V.4
Cadene, M.5
Chait, B.T.6
Mackinnon, R.7
-
3
-
-
0037198626
-
Crystal structure and mechanism of a calcium-gated potassium channel
-
Jiang Y, Lee A, Chen J, Cadene M, Chait BT, MacKinnon R (2002) Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417:515-522
-
(2002)
Nature
, vol.417
, pp. 515-522
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Cadene, M.4
Chait, B.T.5
Mackinnon, R.6
-
4
-
-
23244456428
-
Crystal structure of a mammalian voltagedependent Shaker family K + channel
-
Long SB, Campbell EB, Mackinnon R (2005) Crystal structure of a mammalian voltagedependent Shaker family K + channel. Science 309:897-903
-
(2005)
Science
, vol.309
, pp. 897-903
-
-
Long, S.B.1
Campbell, E.B.2
Mackinnon, R.3
-
5
-
-
72049124287
-
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
-
Sobolevsky AI, Rosconi MP, Gouaux E (2009) X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature 462:745-756
-
(2009)
Nature
, vol.462
, pp. 745-756
-
-
Sobolevsky, A.I.1
Rosconi, M.P.2
Gouaux, E.3
-
6
-
-
34548813656
-
Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH
-
Jasti J, Furukawa H, Gonzales EB, Gouaux E (2007) Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. Nature 449:316-323
-
(2007)
Nature
, vol.449
, pp. 316-323
-
-
Jasti, J.1
Furukawa, H.2
Gonzales, E.B.3
Gouaux, E.4
-
7
-
-
67949092829
-
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
-
Gonzales EB, Kawate T, Gouaux E (2009) Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. Nature 460: 599-604
-
(2009)
Nature
, vol.460
, pp. 599-604
-
-
Gonzales, E.B.1
Kawate, T.2
Gouaux, E.3
-
8
-
-
67949117176
-
Crystal structure of the ATP-gated P2X (4) ion channel in the closed state
-
Kawate T, Michel JC, Birdsong WT, Gouaux E (2009) Crystal structure of the ATP-gated P2X (4) ion channel in the closed state. Nature 460:592-598
-
(2009)
Nature
, vol.460
, pp. 592-598
-
-
Kawate, T.1
Michel, J.C.2
Birdsong, W.T.3
Gouaux, E.4
-
9
-
-
84860785529
-
Molecular mechanism of ATP binding and ion channel activation in P2X receptors
-
Hattori M, Gouaux E (2012) Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature 485:207-212
-
(2012)
Nature
, vol.485
, pp. 207-212
-
-
Hattori, M.1
Gouaux, E.2
-
11
-
-
56649103766
-
Altered functional properties of a TRPM2 variant in Guamanian ALS and PD
-
Hermosura MC, Cui AM, Go RC, Davenportb B, Shetlera CM, Heizerb JW, Schmitzc C, Mocza G, Garrutod RM, Perraudb A-L (2008) Altered functional properties of a TRPM2 variant in Guamanian ALS and PD. Proc Natl Acad Sci U S A 105:18029-18034
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18029-18034
-
-
Hermosura, M.C.1
Cui, A.M.2
Go, R.C.3
Davenportb, B.4
Shetlera, C.M.5
Heizerb, J.W.6
Schmitzc, C.7
Mocza, G.8
Garrutod, R.M.9
Perraudb, A.-L.10
-
12
-
-
77950941000
-
Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions
-
Roger S, Mei ZZ, Baldwin JM, Dong L, Bradley H, Baldwin SA, Surprenant A, Jiang LH (2010) Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions. J Psychiatr Res 44:347-355
-
(2010)
J Psychiatr Res
, vol.44
, pp. 347-355
-
-
Roger, S.1
Mei, Z.Z.2
Baldwin, J.M.3
Dong, L.4
Bradley, H.5
Baldwin, S.A.6
Surprenant, A.7
Jiang, L.H.8
-
13
-
-
84862777282
-
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity
-
Sorge RE, Trang T, Dorfman R et al (2012) Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med 18:595-599
-
(2012)
Nat Med
, vol.18
, pp. 595-599
-
-
Sorge, R.E.1
Trang, T.2
Dorfman, R.3
-
14
-
-
2642699794
-
Rapid and ef ficient sitespeci fic mutagenesis without phenotypic selection
-
Kunkel TA (1985) Rapid and ef ficient sitespeci fic mutagenesis without phenotypic selection. Proc Natl Acad Sci 82:488-492
-
(1985)
Proc Natl Acad Sci
, vol.82
, pp. 488-492
-
-
Kunkel, T.A.1
-
15
-
-
0022429789
-
The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate modi fied DNA
-
Taylor JW, Ott J, Eckstein F (1985) The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate modi fied DNA. Nucleic Acids Res 13:8765-8785
-
(1985)
Nucleic Acids Res
, vol.13
, pp. 8765-8785
-
-
Taylor, J.W.1
Ott, J.2
Eckstein, F.3
-
16
-
-
0028566384
-
Site-directed mutagenesis of double-stranded DNA by the polymerase chain reaction
-
Weiner MP, Costa GL, Schoettlin W, Cline J, Mathur E, Bauer JC (1994) Site-directed mutagenesis of double-stranded DNA by the polymerase chain reaction. Gene 151:119-123
-
(1994)
Gene
, vol.151
, pp. 119-123
-
-
Weiner, M.P.1
Costa, G.L.2
Schoettlin, W.3
Cline, J.4
Mathur, E.5
Bauer, J.C.6
-
17
-
-
0023929638
-
A simple and rapid method for the selection of oligonucleotide-directed mutants
-
Vandeyar MA, Weiner MP, Hutton CJ, Batt CA (1988) A simple and rapid method for the selection of oligonucleotide-directed mutants. Gene 65:129-133
-
(1988)
Gene
, vol.65
, pp. 129-133
-
-
Vandeyar, M.A.1
Weiner, M.P.2
Hutton, C.J.3
Batt, C.A.4
-
18
-
-
0032321387
-
Site-directed mutagenesis
-
Ishii TM, Zerr P, Xia XM, Bond CT, Maylie J, Adelman JP (1998) Site-directed mutagenesis. Methods Enzymol 293:53-71
-
(1998)
Methods Enzymol
, vol.293
, pp. 53-71
-
-
Ishii, T.M.1
Zerr, P.2
Xia, X.M.3
Bond, C.T.4
Maylie, J.5
Adelman, J.P.6
-
19
-
-
0346992128
-
A one-tube, two-step polymerase chain reaction-based site-directed mutagenesis method with simple identification of the mutated product
-
Nagy ZB, Felfoldi F, Tamas L, Puskás LG (2004) A one-tube, two-step polymerase chain reaction-based site-directed mutagenesis method with simple identification of the mutated product. Anal Biochem 324:301-303
-
(2004)
Anal Biochem
, vol.324
, pp. 301-303
-
-
Nagy, Z.B.1
Felfoldi, F.2
Tamas, L.3
Puskás, L.G.4
-
20
-
-
0032894975
-
Helical structure and packing orientation of the S2 segment in the Skaker K + channel
-
Monks SA, Needleman DJ, Miller C (1999) Helical structure and packing orientation of the S2 segment in the Skaker K + channel. J Gen Physiol 113:415-423
-
(1999)
J Gen Physiol
, vol.113
, pp. 415-423
-
-
Monks, S.A.1
Needleman, D.J.2
Miller, C.3
-
21
-
-
79959873314
-
Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore
-
Yang W, Manna PT, Zou J, Luo J, Beech DJ, Sivaprasadarao A, Jiang LH (2011) Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore. J Biol Chem 286:23789-23798
-
(2011)
J Biol Chem
, vol.286
, pp. 23789-23798
-
-
Yang, W.1
Manna, P.T.2
Zou, J.3
Luo, J.4
Beech, D.J.5
Sivaprasadarao, A.6
Jiang, L.H.7
-
22
-
-
77957270790
-
Statedependent inhibition of TRPM2 channel by acidic pH
-
Yang W, Zou J, Xia R, Vaal ML, Seymour VA, Luo J, Beech DJ, Jiang L-H (2010) Statedependent inhibition of TRPM2 channel by acidic pH. J Biol Chem 285:30411-30418
-
(2010)
J Biol Chem
, vol.285
, pp. 30411-30418
-
-
Yang, W.1
Zou, J.2
Xia, R.3
Vaal, M.L.4
Seymour, V.A.5
Luo, J.6
Beech, D.J.7
Jiang, L.-H.8
-
23
-
-
37349124727
-
Identi fication of key residues coordinating functional inhibition of P2X7 receptors by zinc and copper
-
Liu X, Surprenant A, Mao HJ, Roger S, Xia R, Bradley H, Jiang L-H (2008) Identi fication of key residues coordinating functional inhibition of P2X7 receptors by zinc and copper. Mol Pharmacol 73:252-259
-
(2008)
Mol Pharmacol
, vol.73
, pp. 252-259
-
-
Liu, X.1
Surprenant, A.2
Mao, H.J.3
Roger, S.4
Xia, R.5
Bradley, H.6
Jiang, L.-H.7
-
24
-
-
65549148944
-
Identi fication of the amino acid residues in the extracellular domain of rat P2X(7) receptor involved in functional inhibition by acidic pH
-
Liu X, Ma W, Surprenant A, Jiang L-H (2009) Identi fication of the amino acid residues in the extracellular domain of rat P2X(7) receptor involved in functional inhibition by acidic pH. Br J Pharmacol 156:135-142
-
(2009)
Br J Pharmacol
, vol.156
, pp. 135-142
-
-
Liu, X.1
Ma, W.2
Surprenant, A.3
Jiang, L.-H.4
-
25
-
-
85027947630
-
A residue in the TRPM2 channel outer pore is crucial in determining species-dependent sensitivity to extracellular acidic pH
-
Zou J, Yang W, Beech DJ, Jiang L-H (2011) A residue in the TRPM2 channel outer pore is crucial in determining species-dependent sensitivity to extracellular acidic pH. Pflugers Arch 462:293-302
-
(2011)
Pflugers Arch
, vol.462
, pp. 293-302
-
-
Zou, J.1
Yang, W.2
Beech, D.J.3
Jiang, L.-H.4
-
26
-
-
80052216594
-
Pharmacological properties of the rhesus macaque monkey P2X7 receptor
-
Bradley HJ, Browne LE, Yang W, Jiang L-H (2011) Pharmacological properties of the rhesus macaque monkey P2X7 receptor. Br J Pharmacol 164:743-754
-
(2011)
Br J Pharmacol
, vol.164
, pp. 743-754
-
-
Bradley, H.J.1
Browne, L.E.2
Yang, W.3
Jiang, L.-H.4
-
27
-
-
0020959710
-
Studies on transformation of Escherichia coli with plasmids
-
Hanahan D (1983) Studies on transformation of Escherichia coli with plasmids. J Mol Biol 166:557-580
-
(1983)
J Mol Biol
, vol.166
, pp. 557-580
-
-
Hanahan, D.1
-
28
-
-
55549136063
-
Identi fication of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2
-
Xia R, Mei ZZ, Mao HJ, Yang W, Dong L, Bradley H, Beech DJ, Jiang LH (2008) Identi fication of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2. J Biol Chem 283: 27426-27432
-
(2008)
J Biol Chem
, vol.283
, pp. 27426-27432
-
-
Xia, R.1
Mei, Z.Z.2
Mao, H.J.3
Yang, W.4
Dong, L.5
Bradley, H.6
Beech, D.J.7
Jiang, L.H.8
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