Delivery of reprogramming factors into fibroblasts for generation of non-genetic induced pluripotent stem cells using a cationic bolaamphiphile as a non-viral vector

Biomaterials

Volumn 34, Issue 21, 2013, Pages 5336-5343

  Khan, Majad ^a   Narayanan, Karthikeyan ^a   Lu, Hongfang ^a   Choo, Yang ^a   Du, Chan ^a   Wiradharma, Nikken ^a   Yang, Yi Yan ^a   Wan, Andrew C A ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

Cationic bolaamphiphile; Induced pluripotent stem cells; Intracellular delivery; Protein transduction; Reprogramming of fibroblasts; Stem cells

Indexed keywords

BOLAAMPHIPHILES; EMBRYONIC STEM CELLS; GENETIC MODIFICATIONS; INDUCED PLURIPOTENT STEM CELLS; INTRACELLULAR DELIVERY; NEURONAL DIFFERENTIATION; PROTEIN DELIVERY SYSTEMS; PROTEIN TRANSDUCTION;

CELL CULTURE; FIBROBLASTS; GENETIC ENGINEERING; STEM CELLS;

PROTEINS;

ALKALINE PHOSPHATASE; AMPHOPHILE; BOLAAMPHIPHILE; OCTAMER TRANSCRIPTION FACTOR 4; RECOMBINANT PROTEIN; REPROGRAMMING FACTOR; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; EMBRYONIC STEM CELL; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PARTICLE SIZE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNTHESIS; ZETA POTENTIAL;

ANIMALS; BIOLOGICAL ASSAY; CATIONS; CATTLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL NUCLEUS; CELL PROLIFERATION; COLONY-FORMING UNITS ASSAY; FIBROBLASTS; FLOW CYTOMETRY; FURANS; GENETIC VECTORS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, SCID; NEURONS; NUCLEAR REPROGRAMMING; PYRIDONES; RECOMBINANT PROTEINS; SERUM ALBUMIN, BOVINE; TRANSFECTION;

MUS;

EID: 84877058167     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.03.072     Document Type: Article

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