메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

Recombinant Mammaglobin A Adenovirus-Infected Dendritic Cells Induce Mammaglobin A-Specific CD8+ Cytotoxic T Lymphocytes against Breast Cancer Cells In Vitro

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; MAMMAGLOBIN A; TUMOR NECROSIS FACTOR ALPHA; IL10 PROTEIN, HUMAN;

EID: 84877051088     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063055     Document Type: Article
Times cited : (8)

References (45)
  • 1
    • 84890561823 scopus 로고    scopus 로고
    • Epidemic Trend of Female Breast Cancer Incidence in Min hang District, Shanghai
    • He DD, Wang CF, Cao LL, Zhou J, Huang Jun, et al. (2010) Epidemic Trend of Female Breast Cancer Incidence in Min hang District, Shanghai. China Cancer 13: 108-10.
    • (2010) China Cancer , vol.13 , pp. 108-110
    • He, D.D.1    Wang, C.F.2    Cao, L.L.3    Zhou, J.4    Huang, J.5
  • 2
    • 34248204110 scopus 로고    scopus 로고
    • DC-based cancer vaccines
    • Gilboa E, (2007) DC-based cancer vaccines. J Clin Invest 117: 1195-203.
    • (2007) J Clin Invest , vol.117 , pp. 1195-1203
    • Gilboa, E.1
  • 3
    • 79954981035 scopus 로고    scopus 로고
    • Dendritic cells transfected with PEG10 recombinant adenovirus elicit anti-tumor immune response in vitro and in vivo
    • Peng W, Zhao G, Ma Y, Yu H, Wang X, (2011) Dendritic cells transfected with PEG10 recombinant adenovirus elicit anti-tumor immune response in vitro and in vivo. Vaccine 29: 3501-6.
    • (2011) Vaccine , vol.29 , pp. 3501-3506
    • Peng, W.1    Zhao, G.2    Ma, Y.3    Yu, H.4    Wang, X.5
  • 4
    • 79959895629 scopus 로고    scopus 로고
    • Simultaneous in vivo tracking of dendritic cells and priming of an antigen-specific immune response
    • Noh YW, Jang YS, Ahn KJ, Lim YT, Chung BH, (2011) Simultaneous in vivo tracking of dendritic cells and priming of an antigen-specific immune response. Biomaterials 32: 6254-63.
    • (2011) Biomaterials , vol.32 , pp. 6254-6263
    • Noh, Y.W.1    Jang, Y.S.2    Ahn, K.J.3    Lim, Y.T.4    Chung, B.H.5
  • 6
    • 79954640599 scopus 로고    scopus 로고
    • Identification of immunodominant HLA-B7-restricted CD8+ cytotoxic T cell epitopes derived from mammaglobin-A expressed on human breast cancers
    • Ilias Basha H, Tiriveedhi V, Fleming TP, Gillanders WE, Mohanakumar T, (2011) Identification of immunodominant HLA-B7-restricted CD8+ cytotoxic T cell epitopes derived from mammaglobin-A expressed on human breast cancers. Breast Cancer Res Treat 127: 81-9.
    • (2011) Breast Cancer Res Treat , vol.127 , pp. 81-89
    • Ilias Basha, H.1    Tiriveedhi, V.2    Fleming, T.P.3    Gillanders, W.E.4    Mohanakumar, T.5
  • 7
    • 0037689046 scopus 로고    scopus 로고
    • Generation of CD8+ cytotoxic T lymphocytes against breast cancer cells by stimulation with mammaglobin-A-pulsed dendritic cells
    • Manna PP, Jaramillo A, Majumder K, Campbell LG, Fleming TP, et al. (2003) Generation of CD8+ cytotoxic T lymphocytes against breast cancer cells by stimulation with mammaglobin-A-pulsed dendritic cells. Breast Cancer Res Treat 79: 133-6.
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 133-136
    • Manna, P.P.1    Jaramillo, A.2    Majumder, K.3    Campbell, L.G.4    Fleming, T.P.5
  • 8
    • 8744288783 scopus 로고    scopus 로고
    • Recognition of HLA-A2-restricted mammaglobin-A-derived epitopesby CD8+ cytotoxic T lymphocytes from breast cancer patients
    • Jaramillo A, Narayanan K, Campbell LG, Benshoff ND, Lybarger L, et al. (2004) Recognition of HLA-A2-restricted mammaglobin-A-derived epitopesby CD8+ cytotoxic T lymphocytes from breast cancer patients. Breast Cancer Res Treat 88: 29-41.
    • (2004) Breast Cancer Res Treat , vol.88 , pp. 29-41
    • Jaramillo, A.1    Narayanan, K.2    Campbell, L.G.3    Benshoff, N.D.4    Lybarger, L.5
  • 9
    • 77956639937 scopus 로고    scopus 로고
    • Generation of cellular immune responses to HCV NS5 protein through in vivo activation of dendritic cells
    • Wintermeyer P, Gehring S, Eken A, Wands JR, (2010) Generation of cellular immune responses to HCV NS5 protein through in vivo activation of dendritic cells. J Viral Hepat 17: 705-13.
    • (2010) J Viral Hepat , vol.17 , pp. 705-713
    • Wintermeyer, P.1    Gehring, S.2    Eken, A.3    Wands, J.R.4
  • 10
    • 57849168395 scopus 로고    scopus 로고
    • Enhancement of cytotoxic T lymphocyte activity by dendritic cells loaded with Tat-protein transduction domain-fused hepatitis B virus core antigen
    • Chen X, Yu Y, Pan Q, Tang Z, Han J, et al. (2008) Enhancement of cytotoxic T lymphocyte activity by dendritic cells loaded with Tat-protein transduction domain-fused hepatitis B virus core antigen. Acta Biochim Biophys Sin 40: 996-1004.
    • (2008) Acta Biochim Biophys Sin , vol.40 , pp. 996-1004
    • Chen, X.1    Yu, Y.2    Pan, Q.3    Tang, Z.4    Han, J.5
  • 11
    • 20244389660 scopus 로고    scopus 로고
    • Critical role of the Th1/Tc1 circuit for the generation of tumor-specific CTL during tumor eradication in vivo by Th1-cell therapy
    • Chamoto K, Kosaka A, Tsuji T, Matsuzaki J, Sato T, et al. (2003) Critical role of the Th1/Tc1 circuit for the generation of tumor-specific CTL during tumor eradication in vivo by Th1-cell therapy. Cancer Sci 94: 924-8.
    • (2003) Cancer Sci , vol.94 , pp. 924-928
    • Chamoto, K.1    Kosaka, A.2    Tsuji, T.3    Matsuzaki, J.4    Sato, T.5
  • 12
    • 65949112915 scopus 로고    scopus 로고
    • Selective addition of CXCR3+CCR4-CD4+ Th1 cells enhances generation of cytotoxic T cells by dendritic cells in vitro
    • Yoon SH, Yun SO, Park JY, Won HY, Kim EK, et al. (2009) Selective addition of CXCR3+CCR4-CD4+ Th1 cells enhances generation of cytotoxic T cells by dendritic cells in vitro. Exp Mol Med 41: 161-70.
    • (2009) Exp Mol Med , vol.41 , pp. 161-170
    • Yoon, S.H.1    Yun, S.O.2    Park, J.Y.3    Won, H.Y.4    Kim, E.K.5
  • 13
    • 79953210704 scopus 로고    scopus 로고
    • Dendritic cells adenovirally-transduced with full-length mesothelin cDNA elicit mesothelin-specific cytotoxicity against pancreatic cancer cell lines in vitro
    • Miyazawa M, Iwahashi M, Ojima T, Katsuda M, Nakamura M, et al. (2011) Dendritic cells adenovirally-transduced with full-length mesothelin cDNA elicit mesothelin-specific cytotoxicity against pancreatic cancer cell lines in vitro. Cancer Lett 305: 32-9.
    • (2011) Cancer Lett , vol.305 , pp. 32-39
    • Miyazawa, M.1    Iwahashi, M.2    Ojima, T.3    Katsuda, M.4    Nakamura, M.5
  • 14
    • 71149112331 scopus 로고    scopus 로고
    • Binding of prostate-specific membrane antigen to dendritic cells: a critical step in vaccine preparation
    • Garetto S, Sizzano F, Brusa D, Tizzani A, Malavasi F, et al. (2009) Binding of prostate-specific membrane antigen to dendritic cells: a critical step in vaccine preparation. Cytotherapy 11: 1090-100.
    • (2009) Cytotherapy , vol.11 , pp. 1090-1100
    • Garetto, S.1    Sizzano, F.2    Brusa, D.3    Tizzani, A.4    Malavasi, F.5
  • 16
    • 0028074616 scopus 로고
    • Isolation of differentially expressed sequence tags from human breast cancer
    • Watson MA, Fleming TP, (1994) Isolation of differentially expressed sequence tags from human breast cancer. Cancer Res 54: 4598-602.
    • (1994) Cancer Res , vol.54 , pp. 4598-4602
    • Watson, M.A.1    Fleming, T.P.2
  • 17
    • 0030056285 scopus 로고    scopus 로고
    • Mammaglobin, a mammary specific member of the uteroglobin gene family, is overexpressed in human breast cancer
    • Watson MA, Fleming TP, (1996) Mammaglobin, a mammary specific member of the uteroglobin gene family, is overexpressed in human breast cancer. Cancer Res 56: 860-5.
    • (1996) Cancer Res , vol.56 , pp. 860-865
    • Watson, M.A.1    Fleming, T.P.2
  • 18
    • 0034503089 scopus 로고    scopus 로고
    • Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer
    • Fleming TP, Watson MA, (2000) Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer. Ann N Y Acad Sci 923: 78-89.
    • (2000) Ann N Y Acad Sci , vol.923 , pp. 78-89
    • Fleming, T.P.1    Watson, M.A.2
  • 20
    • 70350207180 scopus 로고    scopus 로고
    • Transcriptional IL-15-Directed in vivo DC Targeting DNA Vaccine
    • Tian S, Liu Z, Donahue C, Noh HS, Falo LD Jr, et al. (2009) Transcriptional IL-15-Directed in vivo DC Targeting DNA Vaccine. Gene Ther 16: 1260-70.
    • (2009) Gene Ther , vol.16 , pp. 1260-1270
    • Tian, S.1    Liu, Z.2    Donahue, C.3    Noh, H.S.4    Falo Jr., L.D.5
  • 22
    • 84873380722 scopus 로고    scopus 로고
    • Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells
    • Kim J, Jayaprakasha GK, Patil BS, (2013) Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct 4(2): 258-65.
    • (2013) Food Funct , vol.4 , Issue.2 , pp. 258-265
    • Kim, J.1    Jayaprakasha, G.K.2    Patil, B.S.3
  • 23
    • 81555219225 scopus 로고    scopus 로고
    • Detection of mammaglogin A in blood from breast cancer patients, before and after treatment, using a one-tube nested PCR protocol. Association with the absence of tumor estrogen receptors
    • Ceballos MP, Zumoffen C, Massa E, Cipulli G, Funes CC, et al. (2011) Detection of mammaglogin A in blood from breast cancer patients, before and after treatment, using a one-tube nested PCR protocol. Association with the absence of tumor estrogen receptors. Clin Biochem 44: 1429-33.
    • (2011) Clin Biochem , vol.44 , pp. 1429-1433
    • Ceballos, M.P.1    Zumoffen, C.2    Massa, E.3    Cipulli, G.4    Funes, C.C.5
  • 24
    • 42249100865 scopus 로고    scopus 로고
    • Detection of mammaglobin mRNA in peripheral blood is associated with high grade breast cancer: interim results of a prospective cohort study
    • Mikhitarian K, Martin RH, Ruppel MB, Gillanders WE, Hoda R, et al. (2008) Detection of mammaglobin mRNA in peripheral blood is associated with high grade breast cancer: interim results of a prospective cohort study. BMC Cancer 8: 55.
    • (2008) BMC Cancer , vol.8 , pp. 55
    • Mikhitarian, K.1    Martin, R.H.2    Ruppel, M.B.3    Gillanders, W.E.4    Hoda, R.5
  • 25
    • 79959254816 scopus 로고    scopus 로고
    • Expression of human mammaglobin and clinicopathologic correlations in breast cancer: The findings in Malaysia
    • Al-Joudi FS, Kaid FA, Ishak I, Mohamed N, Osman K, et al. (2011) Expression of human mammaglobin and clinicopathologic correlations in breast cancer: The findings in Malaysia. Indian J Pathol Microbiol 54(2): 284-9.
    • (2011) Indian J Pathol Microbiol , vol.54 , Issue.2 , pp. 284-289
    • Al-Joudi, F.S.1    Kaid, F.A.2    Ishak, I.3    Mohamed, N.4    Osman, K.5
  • 26
    • 67749142116 scopus 로고    scopus 로고
    • Dendritic cells loaded with HIV-1 p24 proteins adsorbed on surfactant-free anionic PLA nanoparticles induce enhanced cellular immune responses against HIV-1 after vaccination
    • Aline F, Brand D, Pierre J, Roingeard P, Séverine M, et al. (2009) Dendritic cells loaded with HIV-1 p24 proteins adsorbed on surfactant-free anionic PLA nanoparticles induce enhanced cellular immune responses against HIV-1 after vaccination. Vaccine 27: 5284-91.
    • (2009) Vaccine , vol.27 , pp. 5284-5291
    • Aline, F.1    Brand, D.2    Pierre, J.3    Roingeard, P.4    Séverine, M.5
  • 27
    • 0029831666 scopus 로고    scopus 로고
    • High level IL-12 production by murine dendritic cells up-regulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10
    • Koch F, Stanzl U, Jennewein P, Janke K, Heufler C, et al. (1996) High level IL-12 production by murine dendritic cells up-regulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. J Exp Med 184: 741-6.
    • (1996) J Exp Med , vol.184 , pp. 741-746
    • Koch, F.1    Stanzl, U.2    Jennewein, P.3    Janke, K.4    Heufler, C.5
  • 28
    • 0032849641 scopus 로고    scopus 로고
    • Dendritic cell: expansion and differentiation with hematopoietic growth factors
    • Young JW, (1999) Dendritic cell: expansion and differentiation with hematopoietic growth factors. Curr Opin Hematol. 6(3): 135-44.
    • (1999) Curr Opin Hematol , vol.6 , Issue.3 , pp. 135-144
    • Young, J.W.1
  • 29
    • 7044262768 scopus 로고    scopus 로고
    • Defective tumor necrosis factor alpha-induced maturation of monocyte-derived dendritic cells in patients with myelodysplastic syndromes
    • Micheva I, Thanopoulou E, Michalopoulou S, Karakantza M, Kouraklis-Symeonidis A, et al. (2004) Defective tumor necrosis factor alpha-induced maturation of monocyte-derived dendritic cells in patients with myelodysplastic syndromes. Clin Immunol 113(3): 310-7.
    • (2004) Clin Immunol , vol.113 , Issue.3 , pp. 310-317
    • Micheva, I.1    Thanopoulou, E.2    Michalopoulou, S.3    Karakantza, M.4    Kouraklis-Symeonidis, A.5
  • 30
    • 0031839320 scopus 로고    scopus 로고
    • The role of tumor necrosis factor-a in modulating the quantity of peripheral blood-derived, cytokine driven human dendritic cells and its role in enhancing the quality of dendritic cell function in presenting soluble antigens to cd4+ t cells in vitro
    • Chen B, Shi Y, Smith JD, Chol D, Geiger JD, et al. (1998) The role of tumor necrosis factor-a in modulating the quantity of peripheral blood-derived, cytokine driven human dendritic cells and its role in enhancing the quality of dendritic cell function in presenting soluble antigens to cd4+ t cells in vitro. Blood 91(12): 4652-61.
    • (1998) Blood , vol.91 , Issue.12 , pp. 4652-4661
    • Chen, B.1    Shi, Y.2    Smith, J.D.3    Chol, D.4    Geiger, J.D.5
  • 31
    • 78649967714 scopus 로고    scopus 로고
    • The role of tumor necrosis factor-a for interleukin-10 production by murine dendritic cells
    • Hirata N, Yanagawa Y, Ogura H, Satoh M, Noguchi M, et al. (2011) The role of tumor necrosis factor-a for interleukin-10 production by murine dendritic cells. Cell immunol 266(2): 165-71.
    • (2011) Cell Immunol , vol.266 , Issue.2 , pp. 165-171
    • Hirata, N.1    Yanagawa, Y.2    Ogura, H.3    Satoh, M.4    Noguchi, M.5
  • 32
    • 0037073538 scopus 로고    scopus 로고
    • Infection of mouse bone marrow- derived cells with recombinant adenovirus vectors leads to presentation of eccoded antigen by both MHC class I and class II molecules-potential benefits in vaccine design
    • Herrera OB, Brett S, Lechler RI, (2002) Infection of mouse bone marrow- derived cells with recombinant adenovirus vectors leads to presentation of eccoded antigen by both MHC class I and class II molecules-potential benefits in vaccine design. Vaccine 21(3-4): 231-42.
    • (2002) Vaccine , vol.21 , Issue.3-4 , pp. 231-242
    • Herrera, O.B.1    Brett, S.2    Lechler, R.I.3
  • 33
    • 54849406164 scopus 로고    scopus 로고
    • Regulation of antigen presentation machinery in human dendritic cells by recombinant adenovirus
    • Vujanovic L, Theresa L, Potter DM, Chu J, Ferrone S, et al. (2009) Regulation of antigen presentation machinery in human dendritic cells by recombinant adenovirus. Cancer Immunol Immunother 58(1): 121-33.
    • (2009) Cancer Immunol Immunother , vol.58 , Issue.1 , pp. 121-133
    • Vujanovic, L.1    Theresa, L.2    Potter, D.M.3    Chu, J.4    Ferrone, S.5
  • 34
    • 42649111674 scopus 로고    scopus 로고
    • Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene
    • Xie LH, Sin FW, Cheng SC, Cheung YK, Chan KT, et al. (2008) Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene. Cancer Immunol Immunother 57: 1029-38.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1029-1038
    • Xie, L.H.1    Sin, F.W.2    Cheng, S.C.3    Cheung, Y.K.4    Chan, K.T.5
  • 35
    • 81855204935 scopus 로고    scopus 로고
    • Improved efficacy of therapeutic vaccination with dendritic cells pulsed with tumor cell lysate against hepatocellular carcinoma by introduction of 2 tandem repeats of microbial HSP70 peptide epitope 407-426 and OK-432.Int Immunopharmacol
    • Ge C, Xing Y, Wang Q, Xiao W, Lu Y, et al. (2011) Improved efficacy of therapeutic vaccination with dendritic cells pulsed with tumor cell lysate against hepatocellular carcinoma by introduction of 2 tandem repeats of microbial HSP70 peptide epitope 407-426 and OK-432.Int Immunopharmacol. 11: 2200-7.
    • (2011) , vol.11 , pp. 2200-2207
    • Ge, C.1    Xing, Y.2    Wang, Q.3    Xiao, W.4    Lu, Y.5
  • 36
    • 0033926456 scopus 로고    scopus 로고
    • Murine dentritic cells infected with adenovirus vectors show signs of activation
    • Hirschowitz EA, Weaver JD, Hidalgo GE, Doherty DE, (2000) Murine dentritic cells infected with adenovirus vectors show signs of activation. Gene therapy 7: 1112-20.
    • (2000) Gene Therapy , vol.7 , pp. 1112-1120
    • Hirschowitz, E.A.1    Weaver, J.D.2    Hidalgo, G.E.3    Doherty, D.E.4
  • 37
    • 1942533432 scopus 로고    scopus 로고
    • Adenovirus- induced maturation of dendritic cells through a PI3 kinase-mediated TNF-a induction pathway
    • Philpott NJ, Nociari M, Elkon KB, Falck-Pedersen E, (2004) Adenovirus- induced maturation of dendritic cells through a PI3 kinase-mediated TNF-a induction pathway. Proc Natl Acad Sci U S A 101(16): 6200-5.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.16 , pp. 6200-6205
    • Philpott, N.J.1    Nociari, M.2    Elkon, K.B.3    Falck-Pedersen, E.4
  • 38
    • 0033819679 scopus 로고    scopus 로고
    • Recombinant adenovirus induces maturation of dendritic cells via an NF-KB-dependent pathway
    • Morelli AE, Larregina AT, Ganster RW, Zahorchak AF, Plowey JM, et al. (2000) Recombinant adenovirus induces maturation of dendritic cells via an NF-KB-dependent pathway. J Virol 74(20): 9617-28.
    • (2000) J Virol , vol.74 , Issue.20 , pp. 9617-9628
    • Morelli, A.E.1    Larregina, A.T.2    Ganster, R.W.3    Zahorchak, A.F.4    Plowey, J.M.5
  • 39
    • 0029874138 scopus 로고
    • The NF- n B and In B proteins: new discoveries and insights
    • Balwin AS Jr, (1995) The NF- n B and In B proteins: new discoveries and insights. Annu Rev Immunol 14: 649-83.
    • (1995) Annu Rev Immunol , vol.14 , pp. 649-683
    • Balwin Jr., A.S.1
  • 40
    • 77956944508 scopus 로고    scopus 로고
    • Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo
    • Wu YG, Wu GZ, Wang L, Zhang YY, Li Z, et al. (2010) Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo. Med Oncol 27: 736-42.
    • (2010) Med Oncol , vol.27 , pp. 736-742
    • Wu, Y.G.1    Wu, G.Z.2    Wang, L.3    Zhang, Y.Y.4    Li, Z.5
  • 42
    • 84859014918 scopus 로고    scopus 로고
    • Enhancement of CTLs induced by DCs loaded with ubiquitinated hepatitis B virus core antigen
    • Chen JH, Yu YS, Chen XH, Liu HH, Zang GQ, et al. (2012) Enhancement of CTLs induced by DCs loaded with ubiquitinated hepatitis B virus core antigen. World J Gastroenterol 18: 1319-27.
    • (2012) World J Gastroenterol , vol.18 , pp. 1319-1327
    • Chen, J.H.1    Yu, Y.S.2    Chen, X.H.3    Liu, H.H.4    Zang, G.Q.5
  • 43
    • 80655144899 scopus 로고    scopus 로고
    • A High-Affinity T-Helper Epitope Enhances Peptide-Pulsed Dendritic Cell-Based Vaccine
    • Li A, Xiong S, Lin Y, Liu R, Chu Y, (2011) A High-Affinity T-Helper Epitope Enhances Peptide-Pulsed Dendritic Cell-Based Vaccine. DNA Cell Biol 30: 883-92.
    • (2011) DNA Cell Biol , vol.30 , pp. 883-892
    • Li, A.1    Xiong, S.2    Lin, Y.3    Liu, R.4    Chu, Y.5
  • 44
    • 84355161543 scopus 로고    scopus 로고
    • Identification of HLA-A24- restricted CD8(+) cytotoxic T-cell epitopes derived from mammaglobin-A, a human breast cancer-associated antigen
    • Tiriveedhi V, Sarma NJ, Subramanian V, Fleming TP, Gillanders WE, et al. (2012) Identification of HLA-A24- restricted CD8(+) cytotoxic T-cell epitopes derived from mammaglobin-A, a human breast cancer-associated antigen. Hum Immunol 73: 11-6.
    • (2012) Hum Immunol , vol.73 , pp. 11-16
    • Tiriveedhi, V.1    Sarma, N.J.2    Subramanian, V.3    Fleming, T.P.4    Gillanders, W.E.5
  • 45
    • 0036774591 scopus 로고    scopus 로고
    • Tetramer binding and secretion of interferon-a in response to antigenic stimulation are compatible with a range of affinities of MHC:TCR interaction and distinct programs of cytotoxic T-lymphocyte activation
    • Wei CH, Uhlin M, Masucci MG, Levitsky V, (2002) Tetramer binding and secretion of interferon-a in response to antigenic stimulation are compatible with a range of affinities of MHC:TCR interaction and distinct programs of cytotoxic T-lymphocyte activation. Hum Immunol 63: 821-33.
    • (2002) Hum Immunol , vol.63 , pp. 821-833
    • Wei, C.H.1    Uhlin, M.2    Masucci, M.G.3    Levitsky, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.