The role of tumor necrosis factor α in modulating the quantity of peripheral blood-derived, cytokine-driven human dendritic cells and its role in enhancing the quality of dendritic cell function in presenting soluble antigens to CD4+ T cells in vitro

Blood

Volumn 91, Issue 12, 1998, Pages 4652-4661

  Chen, Bing Guan ^a   Shi, Yijun ^a   Smith, Jeffrey D ^a   Choi, David ^a   Geiger, James D ^a   Mulé, James J ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD4 ANTIGEN; CD86 ANTIGEN; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 4; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TETANUS TOXOID;

ANTIGEN PRESENTATION; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; HUMAN; HUMAN CELL; MIXED LYMPHOCYTE REACTION; PHAGOCYTOSIS; PRIORITY JOURNAL;

EID: 0031839320     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.12.4652     Document Type: Article

References (48)

1. Steinman R: The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 9:271, 1991
2. Stingl G, Bergstresser PR: Dendritic cells: A major story unfolds. Immunol Today 16:330, 1995
3. Porgador A, Gilboa E: Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes. J Exp Med 182:244, 1995
4. Celluzzi CM, Mayordomo JI, Storkus WJ, Lotze MT, Falo LD Jr: Peptide-pulsed dendritic cells induce antigen-specific, CTL-mediated protective tumor immunity. J Exp Med 183:283, 1996
5. Geraghty PJ, Fields RC, Mulé JJ: Vaccination with tumor-pulsed splenic dendritic cells mediates immunity to a poorly-immunogenic tumor. Surg Forum 47:459, 1996
6. Cohen PJ, Cohen PA, Rosenberg SA, Katz SI, Mulé JJ: Murine epidermal Langerhans cells and splenic dendritic cells present tumor-associated antigens to primed T cells. Eur J Immunol 24:315, 1994
7. + T cells from mice immunized to syngeneic sarcomas recognize distinct, non-shared tumor antigens. Cancer Res 54:1055, 1994
8. Guery JC, Adorini L: Dendritic cells are the most efficient in presenting endogenous naturally processed self-epitopes to class II-restricted T cells. J Immunol 154:536, 1995
9. + T lymphocytes by human blood dendritic cells in vitro. J Clin Invest 90:229, 1992
10. Starling GC, McLellan AD, Egner W, Sorg RV, Fawcett J, Sommons DL, Hart DNJ: Intercellular adhesion molecule-3 is the predominant co-stimulatory ligand for leukocyte function antigen-1 on human blood dendritic cells. Eur J Immunol 25:2528, 1995
11. + T cells. J Immunol 154:5071, 1995
12. Heufler C, Koch F, Stanzle U, Topar G, Wysocka M, Trinchieri G, Enk A, Steinman RM, Romani N, Schuler G: Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-γ production by T helper 1 cells. Eur J Immunol 26:659, 1996
13. Böhm W, Schirmbeck R, Elbe A. Melber K, Diminky D, Kraal G, Rooijen NV, Barenholz Y, Reimann J: Exogenous hepatitis B surface antigen particles precessed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. J Immunol 155:3313, 1995
14. Manickan E, Kanangat S, Rouse RJ, Yu Z, Rouse BT: Enhancement of immune response to naked DNA vaccine by immunization with transfected dendritic cells. J Leukoc Biol 61:125, 1997
15. Dubois B, Vanbervliet B. Fayette J, Massacrier C, Kooten CV, Brière F, Banchereau J, Caux C: Dendritic cells enhances growth and differentiation of CD40-activated B lymphocytes. J Exp Med 185:941, 1997
16. Romani N, Kampgen E, Koch F, Heufler C, Schuler G: Dendritic cell production of cytokines and responses to cytokines. Int Rev Immunol 6:151, 1990
17. + blood dendritic cells. Blood 86:3295, 1995
18. Tsai V, Southwood S, Sidney J, Sakaguchi K, Kawakami Y, Appella E, Sette A, Celis E: Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells. J Immunol 158:1796, 1997
19. Mayordomo JI, Zorina T, Storkus WJ, Zitvogel L, Celluzzi C, Falo LD, Melief CJ, Ildstad ST, Kast WM, Deleo AB, Lotze MT: Bone-marrow derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nat Med 1:1297, 1995
20. Paglia P, Chiodoni C, Rodolfo M. Colombo MP: Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo. J Exp Med 183:317, 1996
21. Boczkowski D, Nair SK, Snyder D, Gilboa E: Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. J Exp Med 184:465, 1996
22. Condon C, Watkins SC, Celluzzi CM, Thompson K, Falo LD Jr: DNA-based immunization by in vivo transfection of dendritic cells. Nat Med 2:1122, 1996
23. Hsu FJ, Benike C, Fagnoni F, Liles TM, Czerwinski D, Taidi B, Engleman EG, Levy R: Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med 2:52, 1995
24. Grabbe S, Beissert S, Schwarz T, Granstein RD: Dendritic cells as initiators of tumor immunotherapy? Immunol Today 16:117, 1995
25. + hematopoietic cells. Blood 87:535, 1996
26. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF and TNFα. J Exp Med 184:695, 1996
27. Thomas R, Davis LS, Lipsky PE: Isolation and characterization of human peripheral blood dendritic cells. J Immunol 150:821, 1993
28. Romani N, Gruner S, Brang D, Kämpgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch PO, Steinman RM, Schuler G: Proliferating dendritic cell progenitors in human blood. J Exp Med 180:83, 1994
29. + cell-depleted mobilized peripheral blood can serve as a source of potent dendritic cells. Blood 90:538a, 1997 (abstr, suppl)
30. + peripheral blood monocytes. J Immunol 157:3850, 1996
31. Ludeuig B, Graf D, Gelderblom HR, Becker Y, Kroczek RA, Pauli G: Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40-ligand) and TNFα, but strongly enhanced by interleukin-10. Eur J Immunol 25:1943, 1995
32. Romani N, Reider D, Heuer M, Ebner S, Kämpgen E, Eible B, Niederwieser D, Schuler G: Generation of mature dendritic cells from human blood: An improved method with special regard to clinical application. J Immunol Methods 196:137, 1996
33. Sallusto F, Lanzavecchia A: Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor a. J Exp Med 179:1109, 1994
34. Winzler C, Rovere P, Rescigno M, Granucci F, Penna G, Adorini L, Ricciardi-Castagnoli P: Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J Exp Med 185:317, 1997
35. Grabbe S, Bruvers S, Lindgren AM, Hosoi J, Tan KC, Granstein RD: Tumor antigen presentation by epidermal antigen-presenting cells in the mouse: Modulation by granulocyte-macrophage colony-stimulating factor, tumor necrosis factor α, and ultraviolet radiation. J Leukoc Biol 52:209, 1992
36. Lutz MB, Abmann CU, Girolomoni G, Ricciardi-Castagnoli P: Different cytokines regulate antigen uptake and presentation of a precursor dendritic cell line. Eur J Immunol 26:586, 1996
37. Jacobsen FW, Veiby OP, Stokke T. Jacobsen SEW: TNFα bidirectionally modulates the viability of primitive murine hematopoietic progenitor cells in vitro. J Immunol 157:1193, 1996
38. Galy A, Travis M, Cen D, Chen B: Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 3:459, 1995
39. 2+ precursors. J Immunol 158:2134, 1997
40. Zhou LJ, Tedder TF: CD 14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci USA 93:2588, 1996
41. Bender A, Sapp M, Schuler G, Steinman RM, Bhardwaj N: Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. J Immunol Methods 196:121, 1996
42. Saunders D, Lucas K. Ismaili J, Wu L. Maraskovsky E, Dunn A, Shortman K: Dendritic cell development in culture from thymic precursor cells in the absence of granulocyte/macrophage colony-stimulating factor. J Exp Med 184:2185, 1996
43. Kuchroo VK, Das MR Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH: B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy. Cell 80:707, 1995
44. + tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice. J Exp Med 181:619, 1995
45. Inaba K, Romani N, Steinman RM: An antigen-independent contact mechanism as an early step in T cell-proliferative responses to dendritic cells. J Exp Med 170:527, 1989
46. Koch F, Trockenbacher B, Kämpgen E, Grauer O, Stössel H, Livingstone AM, Schuler G, Romani N: Antigen processing in populations of mature murine dendritic cells is caused by subsets of incompletely matured cells. J Immunol 155:93, 1995
47. Levine TP, Chain BM: Endocytosis by antigen presenting cells: Dendritic cells are as endocytically active as other antigen presenting cells. Proc Natl Acad Sci USA 89:8342, 1992
48. Zaghouani H, Steinman R, Nonacs R, Shah H, Gerhard W, Bona C: Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecules. Science 259:224, 1993