Cancer: A " stem-cell" disease?

Cancer Cell International

Volumn 13, Issue 1, 2013, Pages

  Tu, Shi Ming ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Cancer stem cells; Microenvironment; Paradigm shift; Personalized care; Stem ness

Indexed keywords

ARTICLE; CELL TYPE; GENE MUTATION; GENETIC DISORDER; HOMEOBOX; HUMAN; NEOPLASM; PHENOTYPE; STEM CELL DISEASE;

EID: 84877039263     PISSN: None     EISSN: 14752867     Source Type: Journal    
DOI: 10.1186/1475-2867-13-40     Document Type: Article

References (27)

1. Tu S-M, Lin S-H, Logothetis CJ. Stem-cell origin of metastasis and heterogeneity in solid tumours. Lancet Oncol 2002, 3:508-513. 10.1016/S1470-2045(02)00820-3, 12147437.
2. Tu S-M. Origin of cancers. Clinical perspectives and implications of a stem-cell theory of cancer. Cancer treatment and research; vol. 154 2010, New York: Springer, Rosen ST.
3. Virchow R. Die krankhaften geschwulste [in German]. 3 vols. Berlin: a hirschwald, 1863-1865. From demons and evil spirits to cancer genes 2000, Washington DC: American Registry of Pathology, Fitzgerald PJ.
4. Pierce GB, Dixon FJ. Testicular teratomas I. Demonstration of teratogenesis by metamorphosis of multipotential cells. Cancer 1959, 12:573-583. 10.1002/1097-0142(195905/06)12:3<573::AID-CNCR2820120316>3.0.CO;2-M, 13652104.
5. Stevens LC. Experimental production of testicular teratomas in mice. Proc Natl Acad Sci USA 1964, 52:654-661. 10.1073/pnas.52.3.654, 300322, 14212538.
6. Illmensee K. Reversion of malignancy and normalized differentiation of teratocarcinoma cells in mammals. Genetic mosaics and chimeras in mammals. Basic life science series; vol 12 1978, 3-25. New York: Plenum, Russell LB.
7. Dolberg DS, Bissell MJ. Inability of Rous sarcoma virus to cause sarcomas in the avian embryo. Nature 1984, 309:552-556. 10.1038/309552a0, 6203040.
8. Gerschenson M, Graves K, Carson SD, Wells RS, Pierce GB. Regulation of melanoma by the embryonic skin. Proc Natl Acad Sci USA 1986, 83:7307-7310. 10.1073/pnas.83.19.7307, 386705, 3463969.
9. Houghton J, Stoicov C, Nomura S. Gastric cancer originating from bone marrow-derived cells. Science 2004, 306:1568-1571. 10.1126/science.1099513, 15567866.
10. Wang X, Ouyang H, Yamamoto Y. Residual embryonic cells as precursors of a Barrett's-like metaplasia. Cell 2011, 145:1023-1035. 10.1016/j.cell.2011.05.026, 3125107, 21703447.
11. Herfs M, Yamamoto Y, Laury A. A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proc Natl Acad Sci USA 2012, 109:10516-10521. 10.1073/pnas.1202684109, 3387104, 22689991.
12. Driessens G, Beck B, Caauwe A, Simons BD, Blanpain C. Defining the mode of tumour growth by clonal analysis. Nature 2012, 488:527-530. 10.1038/nature11344, 22854777.
13. Schepers AG, Snippert HJ, Stange DE. Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas. Science 2012, 337:730-735. 10.1126/science.1224676, 22855427.
14. Chen J, Li Y, Yu T-S. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 2012, 488:522-526. 10.1038/nature11287, 3427400, 22854781.
15. Chaffer CL, Brueckmann I, Schell C. Normal and neoplastic nonstemcells can spontaneously convert to a stem-cell state. Proc Natl Acad Sci USA 2011, 108:7950-7955. 10.1073/pnas.1102454108, 3093533, 21498687.
16. Iliopoulos D, Hirsch HA, Wang G, Struhl K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL-6 secretion. Proc Natl Acad Sci USA 2011, 108:1397-1402. 10.1073/pnas.1018898108, 3029760, 21220315.
17. Zhao T, Zhang ZN, Rong Z, Xu Y. Immunogenicity of induced pluripotent stem cells. Nature 2011, 474:212-215. 10.1038/nature10135, 21572395.
18. Zong Y, Huang J, Sankarasharma D. Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling. Proc Natl Acad Sci USA 2012, 109:E3395-E3404. 10.1073/pnas.1217982109, 3528570, 23184966.
19. Xin L, Ide H, Kim Y, Dubey P, Witte ON. In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme. Proc Natl Acad Sci USA 2003, 100(Suppl 1):11896-11903. 304104, 12909713.
20. Reticker-Flynn NE, Braga Malta DF, Winslow MM. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat Commun 2012, 3:1122. 10.1038, 23047680.
21. Berger MF, Lawrence MS, Demichelis F. The genomic complexity of primary human prostate cancer. Nature 2011, 470:214-220. 10.1038/nature09744, 3075885, 21307934.
22. Johnson RA, Wright KD, Poppleton H. Cross-species genomics matches driver mutations and cell compartments to model ependymona. Nature 2010, 466:632-636. 10.1038/nature09173, 2912966, 20639864.
23. Firestein GS, Echeverri F, Yeo M, Zvaifler NJ, Green DR. Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. Proc Natl Acad Sci USA 1997, 94:10895-10900. 10.1073/pnas.94.20.10895, 23522, 9380731.
24. Pap T, Franz JK, Hummel KM, Jeisy E, Gay R, Gay S. Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumor suppressor PTEN at sites of invasive growth and destruction. Arthritis Res 2000, 2:59-64. 10.1186/ar69, 17804, 11219390.
25. Nachman MW, Crowell SL. Estimate of the mutation rate per nucleotide in humans. Genetics 2000, 156:297-304. 1461236, 10978293.
26. Sell S, Pierce GB. Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers. Lab Invest 1994, 70:6-22.
27. Morrison SJ, Kimble J. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 2006, 441:1068-1074. 10.1038/nature04956, 16810241.