Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly(amidoamine) for siRNA delivery

Biomaterials

Volumn 34, Issue 21, 2013, Pages 5303-5316

  Chen, Cheng Jun ^a   Wang, Jian Cheng ^a   Zhao, En Yu ^a   Gao, Ling Yan ^a   Feng, Qiang ^a   Liu, Xiao Yan ^a   Zhao, Zhi Xia ^a   Ma, Xiao Fei ^a   Hou, Wen Jie ^a   Zhang, Liang Ren ^a   Lu, Wan Liang ^a   Zhang, Qiang ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Cholesterol grafted bioreducible poly(amidoamine); Grafting degree; Self assembly cationic nanoparticle; SiRNA delivery; Tumor therapy

Indexed keywords

CATIONIC NANOPARTICLES; GRAFTING DEGREE; POLY(AMIDO AMINE); SIRNA DELIVERY; TUMOR THERAPY;

GENETIC ENGINEERING; GRAFTING (CHEMICAL); MOLECULAR BIOLOGY; NANOPARTICLES; POLYMERS; RNA; SELF ASSEMBLY; TRANSMISSION ELECTRON MICROSCOPY; TUMORS; ZETA POTENTIAL;

CHOLESTEROL;

CHOLESTEROL; NANOPARTICLE; POLYAMIDOAMINE; SELF ASSEMBLY CATIONIC NANOPARTICLE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; CYTOTOXICITY; ELECTRON MICROSCOPE; GENE DELIVERY SYSTEM; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYDRODYNAMICS; IN VITRO STUDY; INTERNALIZATION; PRIORITY JOURNAL; SYNTHESIS; ZETA POTENTIAL;

ANIMALS; CATIONS; CELL PROLIFERATION; CHOLESTEROL; ENDOCYTOSIS; ENDOSOMES; FEMALE; GENE SILENCING; GENE TRANSFER TECHNIQUES; HUMANS; INTRACELLULAR SPACE; LYSOSOMES; MAGNETIC RESONANCE SPECTROSCOPY; MCF-7 CELLS; MICE; MICE, NUDE; NANOPARTICLES; OXIDATION-REDUCTION; PARTICLE SIZE; POLYAMINES; POLYETHYLENEIMINE; RNA, SMALL INTERFERING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84877037923     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.03.056     Document Type: Article

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