Random and block copolymers of bioreducible poly(amido amine)s with high- and low-basicity amino groups: Study of DNA condensation and buffer capacity on gene transfection

Journal of Controlled Release

Volumn 123, Issue 1, 2007, Pages 67-75

  Lin, Chao ^a   Zhong, Zhiyuan ^a   Lok, Martin C ^b   Jiang, Xulin ^b   Hennink, Wim E ^b   Feijen, Jan ^a   Engbersen, Johan F J ^a  

^a UNIVERSITY OF TWENTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Disulfide; Gene delivery; Michael addition; Poly(amido amine); Polyplex

Indexed keywords

BUFFER CAPACITY; DISULFIDES; GENE DELIVERY; MICHAEL ADDITION; POLYAMIDO AMINE; POLYPLEX;

ADDITION REACTIONS; ALKALINITY; AMINO ACIDS; DNA; GENE TRANSFER; PARTICLE SIZE;

BLOCK COPOLYMERS;

AMIDE; AMINE; BUFFER; COPOLYMER; DNA; HISTAMINE; N,N' CYTSAMINEBISACRYLAMIDE; POLY (AMIDO AMINE DERIVATIVE); UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; GENETIC TRANSFECTION; IN VITRO STUDY; MICHAEL ADDITION; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL;

ANIMALS; BUFFERS; CERCOPITHECUS AETHIOPS; COS CELLS; DNA; GENE TRANSFER TECHNIQUES; LACTATES; POLYAMINES; POLYETHYLENE GLYCOLS; TRANSFECTION;

EID: 34648843156     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.07.006     Document Type: Article

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