메뉴 건너뛰기




Volumn 13, Issue 12, 2012, Pages 6155-6157

Common docking domain mutation e322k of the erk2 gene is infrequent in oral squamous cell carcinomas

Author keywords

ERK2; ERK2 mutation; ERK2 mutation in oral cancer; Oral cancer; Oral squamous cell carcinoma

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1;

EID: 84877024092     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.12.6155     Document Type: Article
Times cited : (6)

References (25)
  • 1
    • 33644831522 scopus 로고    scopus 로고
    • A mutation in the common docking domain of ERK2 in a human cancer cell line, which was associated with its constitutive phosphorylation
    • Arvind R, Shimamoto H, Momose F, et al (2005). A mutation in the common docking domain of ERK2 in a human cancer cell line, which was associated with its constitutive phosphorylation. Int J Oncol, 27, 1499-504.
    • (2005) Int J Oncol , vol.27 , pp. 1499-1504
    • Arvind, R.1    Shimamoto, H.2    Momose, F.3
  • 2
    • 79959712087 scopus 로고    scopus 로고
    • Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health
    • Chappell WH, Steelman LS, Long JM, et al (2011). Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health. Oncotarget, 2, 135-64.
    • (2011) Oncotarget , vol.2 , pp. 135-164
    • Chappell, W.H.1    Steelman, L.S.2    Long, J.M.3
  • 3
    • 0029918680 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation
    • Chu Y, Solski PA, Khosravi-Far R, Der CJ, Kelly K (1996). The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J Biol Chem, 271, 6497-501.
    • (1996) J Biol Chem , vol.271 , pp. 6497-6501
    • Chu, Y.1    Solski, P.A.2    Khosravi-Far, R.3    Der, C.J.4    Kelly, K.5
  • 4
    • 84864371119 scopus 로고    scopus 로고
    • Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial
    • Falchook GS, Lewis KD, Infante JR, et al (2012). Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. Lancet Oncol, 13, 782-9.
    • (2012) Lancet Oncol , vol.13 , pp. 782-789
    • Falchook, G.S.1    Lewis, K.D.2    Infante, J.R.3
  • 5
    • 38949183695 scopus 로고    scopus 로고
    • Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy
    • Friday BB, Adjei AA (2008). Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy. Clin Cancer Res, 14, 342-6.
    • (2008) Clin Cancer Res , vol.14 , pp. 342-346
    • Friday, B.B.1    Adjei, A.A.2
  • 6
    • 52049108016 scopus 로고    scopus 로고
    • Specificity of signaling from MAPKs to MAPKAPKs: kinases' tango Nuevo
    • Gaestel M (2008). Specificity of signaling from MAPKs to MAPKAPKs: kinases' tango Nuevo. Front Biosci, 13, 6050-9.
    • (2008) Front Biosci , vol.13 , pp. 6050-6059
    • Gaestel, M.1
  • 7
    • 28444478439 scopus 로고    scopus 로고
    • Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants
    • Greulich H, Chen T-H, Feng W, et al (2005). Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants. PLoS Med, 2, 313.
    • (2005) PLoS Med , vol.2 , pp. 313
    • Greulich, H.1    Chen, T.-H.2    Feng, W.3
  • 8
    • 81255187875 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in patients with oral cavity cancer in a betel nut chewing-prevalent area
    • Hsieh CH, Chang JW, Hsieh JJ (2011). Epidermal growth factor receptor mutations in patients with oral cavity cancer in a betel nut chewing-prevalent area. Head Neck, 33, 1758-64.
    • (2011) Head Neck , vol.33 , pp. 1758-1764
    • Hsieh, C.H.1    Chang, J.W.2    Hsieh, J.J.3
  • 9
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • Keyse SM (2008). Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev, 27, 253-61.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 10
    • 33846641194 scopus 로고    scopus 로고
    • High EGFR expression predicts poor prognosis in patients with squamous cell carcinoma of the oral cavity and oropharynx: a TMA-based immunohistochemical analysis
    • Laimer K, Spizzo G, Gastl G, et al (2007). High EGFR expression predicts poor prognosis in patients with squamous cell carcinoma of the oral cavity and oropharynx: a TMA-based immunohistochemical analysis. Oral Oncol, 43, 193-8.
    • (2007) Oral Oncol , vol.43 , pp. 193-198
    • Laimer, K.1    Spizzo, G.2    Gastl, G.3
  • 11
    • 54949130145 scopus 로고    scopus 로고
    • ERK2 CD domain mutation from a human cancer cell line enhanced anchorage-independent cell growth and abnormality in Drosophila
    • Mahalingam M, Arvind R, Ida H, et al (2008). ERK2 CD domain mutation from a human cancer cell line enhanced anchorage-independent cell growth and abnormality in Drosophila. Oncol Rep, 20, 957-62.
    • (2008) Oncol Rep , vol.20 , pp. 957-962
    • Mahalingam, M.1    Arvind, R.2    Ida, H.3
  • 12
    • 34547209343 scopus 로고    scopus 로고
    • Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
    • McCubrey JA, Steelman LS, Chappell WH, et al (2007). Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta, 1773, 1263-84.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1263-1284
    • McCubrey, J.A.1    Steelman, L.S.2    Chappell, W.H.3
  • 13
    • 0142057133 scopus 로고    scopus 로고
    • Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form
    • Mitra RS, Zhang Z, Henson BS, et al (2003). Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form. Oncogene, 22, 6243-56.
    • (2003) Oncogene , vol.22 , pp. 6243-6256
    • Mitra, R.S.1    Zhang, Z.2    Henson, B.S.3
  • 14
    • 68949086867 scopus 로고    scopus 로고
    • Targeting the RAF-MEK-ERK pathway in cancer therapy
    • Montagut C, Settleman J (2009). Targeting the RAF-MEK-ERK pathway in cancer therapy. Cancer Lett, 283, 125-34.
    • (2009) Cancer Lett , vol.283 , pp. 125-134
    • Montagut, C.1    Settleman, J.2
  • 15
    • 84859976109 scopus 로고    scopus 로고
    • Ras oncogenes in oral cancer: the past 20 years
    • Murugan AK, Munirajan AK, Tsuchida N (2012). Ras oncogenes in oral cancer: the past 20 years. Oral Oncol, 48, 383-92.
    • (2012) Oral Oncol , vol.48 , pp. 383-392
    • Murugan, A.K.1    Munirajan, A.K.2    Tsuchida, N.3
  • 16
    • 0034673718 scopus 로고    scopus 로고
    • Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts
    • Plyte S, Majolini MB, Pacini S, et al (2000). Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts. Oncogene, 19, 1529-37.
    • (2000) Oncogene , vol.19 , pp. 1529-1537
    • Plyte, S.1    Majolini, M.B.2    Pacini, S.3
  • 17
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts PJ, Der CJ (2007). Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene, 26, 3291-310.
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 18
    • 33749635119 scopus 로고    scopus 로고
    • Raf kinases: oncogenesis and drug discovery
    • Schreck R, Rapp UR (2006). Raf kinases: oncogenesis and drug discovery. Int J Cancer, 119, 2261-71.
    • (2006) Int J Cancer , vol.119 , pp. 2261-2271
    • Schreck, R.1    Rapp, U.R.2
  • 19
    • 77955596069 scopus 로고    scopus 로고
    • Global gene expression profiling of oral cavity cancers suggests molecular heterogeneity within anatomic subsites
    • Severino P, Alvares AM, Michaluart P Jr (2008). Global gene expression profiling of oral cavity cancers suggests molecular heterogeneity within anatomic subsites. BMC Res Notes, 1, 113.
    • (2008) BMC Res Notes , vol.1 , pp. 113
    • Severino, P.1    Alvares, A.M.2    Michaluart Jr., P.3
  • 20
    • 79960235543 scopus 로고    scopus 로고
    • Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy
    • Steelman LS, Franklin RA, Abrams SL, et al (2011). Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. Leukemia, 25, 1080-94.
    • (2011) Leukemia , vol.25 , pp. 1080-1094
    • Steelman, L.S.1    Franklin, R.A.2    Abrams, S.L.3
  • 21
    • 79958053606 scopus 로고    scopus 로고
    • Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas
    • Szabó B, Nelhubel GA, Kárpáti A, et al (2011). Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas. Oral Oncol, 47, 487-96.
    • (2011) Oral Oncol , vol.47 , pp. 487-496
    • Szabó, B.1    Nelhubel, G.A.2    Kárpáti, A.3
  • 22
    • 0033788484 scopus 로고    scopus 로고
    • A conserved docking motif in MAP kinases common to substrates, activators and regulators
    • Tanoue T, Adachi M, Moriguchi T, Nishida E (2000). A conserved docking motif in MAP kinases common to substrates, activators and regulators. Nat Cell Biol, 2, 110-6.
    • (2000) Nat Cell Biol , vol.2 , pp. 110-116
    • Tanoue, T.1    Adachi, M.2    Moriguchi, T.3    Nishida, E.4
  • 23
    • 77951961432 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas
    • Van Damme N, Deron P, Van Roy N (2010). Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas. BMC Cancer, 11, 189.
    • (2010) BMC Cancer , vol.11 , pp. 189
    • Van Damme, N.1    Deron, P.2    Van Roy, N.3
  • 24
    • 84864865233 scopus 로고    scopus 로고
    • MicroRNA-214 regulates the acquired resistance to gefitinib via the PTEN/AKT pathway in EGFR-mutant cell lines
    • Wang YS, Wang YH, Xia HP, et al (2012). MicroRNA-214 regulates the acquired resistance to gefitinib via the PTEN/AKT pathway in EGFR-mutant cell lines. Asian Pac J Cancer Prev, 13, 255-60.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 255-260
    • Wang, Y.S.1    Wang, Y.H.2    Xia, H.P.3
  • 25
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions
    • Yoon S, Seger R (2006). The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors, 24, 21-44.
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1    Seger, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.