메뉴 건너뛰기




Volumn 48, Issue 5, 2012, Pages 383-392

Ras oncogenes in oral cancer: The past 20 years

Author keywords

Head and neck; HNSCC; Oncogene; Oral cancer; OSCC risk factors; Ras mutation; Ras signaling

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B;

EID: 84859976109     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.12.006     Document Type: Review
Times cited : (103)

References (135)
  • 3
    • 51649093834 scopus 로고    scopus 로고
    • Recent advances in head and neck cancer
    • Haddad RI, Shin DM. Recent advances in head and neck cancer. N Engl J Med 2008;359(11):1143-54.
    • (2008) N Engl J Med , vol.359 , Issue.11 , pp. 1143-1154
    • Haddad, R.I.1    Shin, D.M.2
  • 5
    • 23644447750 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck
    • DOI 10.1517/14728222.9.4.769
    • Rogers SJ, Box C, Harrington KJ, Nutting C, Rhys-Evans P, Eccles SA. The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck. Expert Opin Ther Targets 2005;9(4):769-90. (Pubitemid 41131678)
    • (2005) Expert Opinion on Therapeutic Targets , vol.9 , Issue.4 , pp. 769-790
    • Rogers, S.J.1    Box, C.2    Harrington, K.J.3    Nutting, C.4    Rhys-Evans, P.5    Eccles, S.A.6
  • 6
    • 84859985511 scopus 로고    scopus 로고
    • Trends in head and neck cancer incidence in Japan during 1965-1999
    • Ioka A, Tsukuma H, Ajiki W, Oshima A. Trends in head and neck cancer incidence in Japan during 1965-1999. Jpn J Clin Oncol 2005;55(2):74-108.
    • (2005) Jpn J Clin Oncol , vol.55 , Issue.2 , pp. 74-108
    • Ioka, A.1    Tsukuma, H.2    Ajiki, W.3    Oshima, A.4
  • 7
    • 0025732716 scopus 로고
    • High frequency of mutation in codon 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma of India
    • Saranath D, Chang SE, Bhoite LT, Panchal RG, Kerr IB, Mehta AR, et al. High frequency of mutation in codon 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma of India. Br J Cancer 1991;63(4):573-8.
    • (1991) Br J Cancer , vol.63 , Issue.4 , pp. 573-578
    • Saranath, D.1    Chang, S.E.2    Bhoite, L.T.3    Panchal, R.G.4    Kerr, I.B.5    Mehta, A.R.6
  • 8
    • 0031763857 scopus 로고    scopus 로고
    • Detection of a rare point mutation at codon 59 and relatively high incidence of H-ras mutation in Indian oral cancer
    • Munirajan AK, Mohanprasad BKC, Shanmugam G, Tsuchida N. Detection of a rare point mutation at codon 59 and relatively high incidence of H-ras mutation in Indian oral cancer. Int J Oncol 1998;13(5):971-4. (Pubitemid 28506066)
    • (1998) International Journal of Oncology , vol.13 , Issue.5 , pp. 971-974
    • Munirajan, A.K.1    Mohanprasad, B.K.C.2    Shanmugam, G.3    Tsuchida, N.4
  • 10
    • 51349154153 scopus 로고    scopus 로고
    • Betel quid chewing, oral cancer and other oral mucosal diseases in Vietnam: A review
    • Reichart PA, Nguyen XH. Betel quid chewing, oral cancer and other oral mucosal diseases in Vietnam: a review. J Oral Pathol Med 2008;37(9):511-4.
    • (2008) J Oral Pathol Med , vol.37 , Issue.9 , pp. 511-514
    • Reichart, P.A.1    Nguyen, X.H.2
  • 11
    • 70349109618 scopus 로고    scopus 로고
    • Detection of two novel mutations and relatively high incidence of H-RAS mutations in Vietnamese oral cancer
    • Murugan AK, Hong NT, Cuc TT, Hung NC, Munirajan AK, Ikeda MA, et al. Detection of two novel mutations and relatively high incidence of H-RAS mutations in Vietnamese oral cancer. Oral Oncol 2009;45(10):e161-166.
    • (2009) Oral Oncol , vol.45 , Issue.10
    • Murugan, A.K.1    Hong, N.T.2    Cuc, T.T.3    Hung, N.C.4    Munirajan, A.K.5    Ikeda, M.A.6
  • 12
    • 0021274505 scopus 로고
    • Utilization of primary health care workers for early detection of oral cancer and precancer cases in Sri Lanka
    • Warnakulasuriya KA, Ekanayake AN, Sivayoham S, Stjernswärd J, Pindborg JJ, Sobin LH, et al. Utilization of primary health care workers for early detection of oral cancer and precancer cases in Sri Lanka. Bull World Health Organ 1984;62(2):243-50. (Pubitemid 14113758)
    • (1984) Bulletin of the World Health Organization , vol.62 , Issue.2 , pp. 243-250
    • Warnakulasuriya, K.A.A.S.1    Ekanayake, A.N.I.2    Sivayoham, S.3
  • 13
    • 14644435804 scopus 로고    scopus 로고
    • Tobacco, oral cancer, and treatment of dependence
    • DOI 10.1016/j.oraloncology.2004.08.010
    • Warnakulasuriya S, Sutherland G, Scully C. Tobacco, oral cancer, and treatment of dependence. Oral Oncol 2005;41(3):244-60. (Pubitemid 40311753)
    • (2005) Oral Oncology , vol.41 , Issue.3 , pp. 244-260
    • Warnakulasuriya, S.1    Sutherland, G.2    Scully, C.3
  • 14
    • 0036155884 scopus 로고    scopus 로고
    • Global epidemiology of areca nut usage
    • DOI 10.1080/13556210020091437
    • Gupta PC, Warnakulasuriya S. Global epidemiology of areca nut usage. Addict Biol 2002;7(1):77-83. (Pubitemid 34087910)
    • (2002) Addiction Biology , vol.7 , Issue.1 , pp. 77-83
    • Gupta, P.C.1    Warnakulasuriya, S.2
  • 15
    • 0027939666 scopus 로고
    • Risk assessment of tobacco, alcohol and diet in oral cancer. A case-control study
    • Rao DN, Ganesh B, Rao RS, Desai PB. Risk assessment of tobacco, alcohol and diet in oral cancer-a case control study. Int J Cancer 1994;58(4):469-73. (Pubitemid 24268083)
    • (1994) International Journal of Cancer , vol.58 , Issue.4 , pp. 469-473
    • Rao, D.N.1    Ganesh, B.2    Rao, R.S.3    Desai, P.B.4
  • 16
    • 4344717607 scopus 로고    scopus 로고
    • Betel-quid and areca nut chewing and some related nirtosamines
    • IARC
    • IARC. Betel-quid and areca nut chewing and some related nirtosamines. IARC Monogr Eval Carcinog Risks Hum 2003;85:11-8.
    • (2003) IARC Monogr Eval Carcinog Risks Hum , vol.85 , pp. 11-18
  • 17
    • 84960567860 scopus 로고
    • British smoking and drinking habits: Variations by birth
    • Balarajan R, Yuen P. British smoking and drinking habits: variations by birth. Community Med 1986;8(3):237-9.
    • (1986) Community Med , vol.8 , Issue.3 , pp. 237-239
    • Balarajan, R.1    Yuen, P.2
  • 18
    • 0025037443 scopus 로고
    • Smoking and drinking in relation to cancers of the oral cavity, pharynx, larynx, and esophagus in Northern Italy
    • Franceschi S, Talamini R, Barra S, Baron AE, Negri E, Bidoli E. Smoking and drinking in relation to cancer of the oral cavity, pharynx, larynx and oesophagus in northern Italy. Cancer Res 1990;50(20):6502-7. (Pubitemid 20348768)
    • (1990) Cancer Research , vol.50 , Issue.20 , pp. 6502-6507
    • Franceschi, S.1    Talamini, R.2    Barra, S.3    Baron, A.E.4    Negri, E.5    Bidoli, E.6    Serraino, D.7    La, V.C.8
  • 20
    • 0018760756 scopus 로고
    • Alcohol-related diseases and carcinogenesis
    • Lieber CS, Seitz HK, Garro AJ, Worner TM. Alcohol-related diseases and carcinogenesis. Cancer Res 1979;39(7 Pt 2):2863-86.
    • (1979) Cancer Res , vol.39 , Issue.7 PART 2 , pp. 2863-2886
    • Lieber, C.S.1    Seitz, H.K.2    Garro, A.J.3    Worner, T.M.4
  • 22
    • 0030577120 scopus 로고    scopus 로고
    • Papillomavirus infections - A major cause of human cancers
    • DOI 10.1016/0304-419X(96)00020-0
    • Zur Hausen H. Papilloma virus infections-a major cause of human cancers. Biochim Biophys Acta 1996;1288(2):F55-78. (Pubitemid 26335492)
    • (1996) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1288 , Issue.2
    • Zur, H.H.1
  • 23
    • 0024535228 scopus 로고
    • The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
    • Dyson N, Howley PM, Munger K, Harlow E. The human papilloma virus-16, E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989;243(4893):934-7. (Pubitemid 19066153)
    • (1989) Science , vol.243 , Issue.4893 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 24
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 1990;63(6):1129-36. (Pubitemid 120035062)
    • (1990) Cell , vol.63 , Issue.6 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 25
    • 0026636412 scopus 로고
    • Oncogenes and tumor-suppressor genes in squamous cell carcinoma of the head and neck
    • Field JK. Oncogenes and tumor-suppressor genes in squamous cell carcinoma of the head and neck. Eur J Cancer b Oral Oncol 1992;28B(1):67-76.
    • (1992) Eur J Cancer B Oral Oncol , vol.28 , Issue.1 B , pp. 67-76
    • Field, J.K.1
  • 26
    • 11844255776 scopus 로고    scopus 로고
    • Contemporary diagnosis and management of head and neck cancer
    • Spiegel JH, Jalisi S. Contemporary diagnosis and management of head and neck cancer. Otolaryngol Clin North Am 2005;38(1):13-4.
    • (2005) Otolaryngol Clin North Am , vol.38 , Issue.1 , pp. 13-14
    • Spiegel, J.H.1    Jalisi, S.2
  • 29
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • DOI 10.1038/nrc1097
    • Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer 2003;3(6):459-65. (Pubitemid 37328850)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 31
    • 0000953693 scopus 로고
    • An unidentified virus which causes the rapid production of tumors in mice
    • Harvey JJ. An unidentified virus which causes the rapid production of tumors in mice. Nature 1964;204:1104-5.
    • (1964) Nature , vol.204 , pp. 1104-1105
    • Harvey, J.J.1
  • 32
    • 0001446334 scopus 로고
    • Morphologic responses to a murine erythroblastosis virus
    • Kirsten WH, Mayer LA. Morphologic responses to a murine erythroblastosis virus. J Natl Cancer Inst 1967;39(2):311-35.
    • (1967) J Natl Cancer Inst , vol.39 , Issue.2 , pp. 311-335
    • Kirsten, W.H.1    Mayer, L.A.2
  • 35
    • 0015843797 scopus 로고
    • Studies on the nucleic acid sequences of Kirsten sarcoma virus: A model for formation of a mammalian RNA-containing sarcoma virus
    • Scolnick EM, Rands E, Williams D, Parks WP. Studies on the nucleic acid sequences of Kirsten sarcoma virus: a model for formation of a mammalian RNA-containing sarcoma virus. J Virol 1973;12(3):458-63.
    • (1973) J Virol , vol.12 , Issue.3 , pp. 458-463
    • Scolnick, E.M.1    Rands, E.2    Williams, D.3    Parks, W.P.4
  • 36
    • 0019990734 scopus 로고
    • Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus
    • Dhar R, Ellis RW, Shih TY, Oroszlan S, Shapiro B, Maizel J, et al. Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. Science 1982;217(4563):934-6.
    • (1982) Science , vol.217 , Issue.4563 , pp. 934-936
    • Dhar, R.1    Ellis, R.W.2    Shih, T.Y.3    Oroszlan, S.4    Shapiro, B.5    Maizel, J.6
  • 37
    • 0019522144 scopus 로고
    • Structure and functions of the Kirsten murine sarcoma virus genome: Molecular cloning of biologically active Kirsten murine sarcoma virus DNA
    • Tsuchida N, Uesugi S. Structure and functions of the Kirsten murine sarcoma virus genome: molecular cloning of biologically active Kirsten murine sarcoma virus DNA. J Virol 1981;38(2):720-7. (Pubitemid 11098363)
    • (1981) Journal of Virology , vol.38 , Issue.2 , pp. 720-727
    • Tsuchida, N.1    Uesugi, S.2
  • 38
    • 0019978519 scopus 로고
    • Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus
    • Tsuchida N, Ryder T, Ohtsubo E. Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus. Science 1982;217(4563):937-9. (Pubitemid 12047353)
    • (1982) Science , vol.217 , Issue.4563 , pp. 937-939
    • Tsuchida, N.1    Ryder, T.2    Ohtsubo, E.3
  • 39
    • 0019855643 scopus 로고
    • The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes
    • DOI 10.1038/292506a0
    • Ellis RW, Defeo D, Shih TY, Gonda MA, Young HA, Tsuchida N, et al. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature 1981;292(5823): 506-11. (Pubitemid 11023981)
    • (1981) Nature , vol.292 , Issue.5823 , pp. 506-511
    • Ellis, R.W.1    DeFeo, D.2    Shih, T.Y.3
  • 41
    • 0019474922 scopus 로고
    • Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts
    • DOI 10.1038/290261a0
    • Shih C, Padhy LC, Murray M, Weinberg RA. Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts. Nature 1981;290(5803):261-4. (Pubitemid 11149660)
    • (1981) Nature , vol.290 , Issue.5803 , pp. 261-264
    • Shih, C.1    Padhy, L.C.2    Murray, M.3    Weinberg, R.A.4
  • 42
    • 0019733024 scopus 로고
    • Human-tumor-derived cell lines contain common and different transforming genes
    • Perucho M, Goldfarb M, Shimizu K, Lama C, Fogh J, Wigler M. Human-tumor-derived cell lines contain common and different transforming genes. Cell 1981;27(3 Pt 2):467-76.
    • (1981) Cell , vol.27 , Issue.3 PART 2 , pp. 467-476
    • Perucho, M.1    Goldfarb, M.2    Shimizu, K.3    Lama, C.4    Fogh, J.5    Wigler, M.6
  • 44
    • 0019960812 scopus 로고
    • A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene
    • DOI 10.1038/300149a0
    • Reddy EP, Reynolds RK, Santos E, Barbacid M. A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature 1982;300(5888):149-52. (Pubitemid 12006347)
    • (1982) Nature , vol.300 , Issue.5888 , pp. 149-152
    • Reddy, E.P.1    Reynolds, R.K.2    Santos, E.3    Barbacid, M.4
  • 45
    • 0019947771 scopus 로고
    • Mechanism of activation of a human oncogene
    • DOI 10.1038/300143a0
    • Tabin CJ, Bradley SM, Bargmann CI, Weinberg RA, Papageorge AG, Scolnick EM, et al. Mechanism of activation of a human oncogene. Nature 1982;300(5888):143-9. (Pubitemid 12006346)
    • (1982) Nature , vol.300 , Issue.5888 , pp. 143-149
    • Tabin, C.J.1    Bradley, S.M.2    Bargmann, C.I.3
  • 46
    • 0020404981 scopus 로고
    • Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change
    • DOI 10.1038/300762a0
    • Taparowsky E, Suard Y, Fasano O, Shimizu K, Goldfarb M, Wigler M. Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change. Nature 1982;300(5894):762-5. (Pubitemid 13224357)
    • (1982) Nature , vol.300 , Issue.5894 , pp. 762-765
    • Taparowsky, E.1    Suard, Y.2    Fasano, O.3
  • 47
    • 0021362206 scopus 로고
    • Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient
    • Santos E, Martin-Zanca D, Reddy EP, Pierotti MA, Della Porta G, Barbacid M. Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient. Science 1984;223(4637):661-4. (Pubitemid 14186799)
    • (1984) Science , vol.223 , Issue.4637 , pp. 661-664
    • Santos, E.1    Martin, Z.D.2    Reddy, E.P.3
  • 48
    • 0024376173 scopus 로고
    • ras Oncogenes in human cancer: A review
    • Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989;49(17):4682-9. (Pubitemid 19213607)
    • (1989) Cancer Research , vol.49 , Issue.17 , pp. 4682-4689
    • Bos, J.L.1
  • 49
    • 0029022018 scopus 로고
    • Mutations of ras genes in human tumors
    • Review
    • Kiaris H, Spandidos DA. Mutations of ras genes in human tumors (Review). Int J Oncol 1995;7(3):413-21.
    • (1995) Int J Oncol , vol.7 , Issue.3 , pp. 413-421
    • Kiaris, H.1    Spandidos, D.A.2
  • 50
    • 0024513581 scopus 로고
    • Activation of oncogenes in human oral cancer cells: A novel codon 13 mutation of c-H-ras-1 and concurrent amplifications of c-erbB-1 and c-myc
    • Tadokoro K, Ueda M, Ohshima T, Fujita K, Rikimaru K, Takahashi N, et al. Activation of oncogenes in human oral cancer cells: a novel codon 13 mutation of c-H-ras-1 and concurrent amplifications of c-erbB-1 and c-myc. Oncogene 1989;4(4):499-505. (Pubitemid 19109765)
    • (1989) Oncogene , vol.4 , Issue.4 , pp. 499-505
    • Tadokoro, K.1    Ueda, M.2    Ohshima, T.3    Fujita, K.4    Rikimaru, K.5    Takahashi, N.6    Enomoto, S.7    Tsuchida, N.8
  • 52
    • 0032527674 scopus 로고    scopus 로고
    • Alterations of p53, cyclin D1, Rb, and H-ras in human oral carcinomas related to tobacco use
    • DOI 10.1002/(SICI)1097-0142(19980715)83:2<204::AID-CNCR2>3.0.CO;2-Q
    • Xu J, Gimenez-Conti IB, Cunningham JE, Collet AM, Luna MA, Lanfranchi HE, et al. Alterations of p53, cyclin D1, Rb, and H-ras in human oral carcinomas related to tobacco use. Cancer 1998;83(2):204-12. (Pubitemid 28317798)
    • (1998) Cancer , vol.83 , Issue.2 , pp. 204-212
    • Xu, J.1    Gimenez-Conti, I.B.2    Cunningham, J.E.3    Collet, A.M.4    Luna, M.A.5    Lanfranchi, H.E.6    Spitz, M.R.7    Conti, C.J.8
  • 55
    • 0027524082 scopus 로고
    • Oncogenes in head and neck cancer
    • Irish JC, Bernstein A. Oncogenes in head and neck cancer. Laryngoscope 1993;103(1):42-52. (Pubitemid 23028804)
    • (1993) Laryngoscope , vol.103 , Issue.1 I , pp. 42-52
    • Irish, J.C.1    Bernstein, A.2
  • 57
    • 34249883955 scopus 로고    scopus 로고
    • Spindle cell carcinoma of head and neck: An immunohistochemical and molecular approach to its pathogenesis
    • DOI 10.1136/jcp.2005.033589
    • Gupta R, Singh S, Hedau S, Nigam S, Das BC, Singh I, et al. Spindle cell carcinoma of head and neck: an immunohistochemical and molecular approach to its pathogenesis. J Clin Pathol 2007;60(5):472-5. (Pubitemid 46867153)
    • (2007) Journal of Clinical Pathology , vol.60 , Issue.5 , pp. 472-475
    • Gupta, R.1    Singh, S.2    Hedau, S.3    Nigam, S.4    Das, B.C.5    Singh, I.6    Mandal, A.K.7
  • 58
    • 49749113623 scopus 로고    scopus 로고
    • Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma
    • Sheikh Ali MA, Gunduz M, Nagatsuka H, Gunduz E, Cengiz B, Fukushima K, et al. Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma. Cancer Sci 2008;99(8): 1589-94.
    • (2008) Cancer Sci , vol.99 , Issue.8 , pp. 1589-1594
    • Sheikh Ali, M.A.1    Gunduz, M.2    Nagatsuka, H.3    Gunduz, E.4    Cengiz, B.5    Fukushima, K.6
  • 59
    • 0033991148 scopus 로고    scopus 로고
    • Ras gene mutations in oral cancer in eastern India
    • Das N, Majumder J, DasGupta UB. Ras gene mutations in oral cancer in eastern India. Oral Oncol 2000;36(1):76-80.
    • (2000) Oral Oncol , vol.36 , Issue.1 , pp. 76-80
    • Das, N.1    Majumder, J.2    DasGupta, U.B.3
  • 60
    • 0029060026 scopus 로고
    • Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck
    • Kiaris H, Spandidos DA, Jones AS, Vaughan ED, Field JK. Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck. Br J Cancer 1995;72(1):123-8.
    • (1995) Br J Cancer , vol.72 , Issue.1 , pp. 123-128
    • Kiaris, H.1    Spandidos, D.A.2    Jones, A.S.3    Vaughan, E.D.4    Field, J.K.5
  • 61
    • 80052177544 scopus 로고    scopus 로고
    • Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
    • Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011;333(6046): 1154-7.
    • (2011) Science , vol.333 , Issue.6046 , pp. 1154-1157
    • Agrawal, N.1    Frederick, M.J.2    Pickering, C.R.3    Bettegowda, C.4    Chang, K.5    Li, R.J.6
  • 63
  • 64
    • 0029687118 scopus 로고    scopus 로고
    • C-Ha-ras oncogene in oral leukoplakia tissues
    • Cheng P, Li H, Yang P, Tan Y. C-Ha-ras oncogene in oral leukoplakia tissues. J Tongji Med Univ 1996;16(1):58-60.
    • (1996) J Tongji Med Univ , vol.16 , Issue.1 , pp. 58-60
    • Cheng, P.1    Li, H.2    Yang, P.3    Tan, Y.4
  • 65
    • 0027352645 scopus 로고
    • Overexpression and amplification of c-myc and c-Ha-ras oncogenes in pleomorphic salivary adenoma
    • Xue H, Situ ZQ, Wang CJ, Wu JZ. Overexpression and amplification of c-myc and c-Ha-ras oncogenes in pleomorphic salivary adenoma. Chin Med J (Engl) 1993;106(1):22-5.
    • (1993) Chin Med J (Engl) , vol.106 , Issue.1 , pp. 22-25
    • Xue, H.1    Situ, Z.Q.2    Wang, C.J.3    Wu, J.Z.4
  • 67
    • 0028370026 scopus 로고
    • Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan
    • Kuo MY, Jeng JH, Chiang CP, Hahn LJ. Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan. J Oral Pathol Med 1994;23(2):70-4. (Pubitemid 2054226)
    • (1994) Journal of Oral Pathology and Medicine , vol.23 , Issue.2 , pp. 70-74
    • Kuo, M.Y.P.1    Jeng, J.H.2    Chiang, C.P.3    Hahn, L.J.4
  • 68
    • 35348931672 scopus 로고    scopus 로고
    • H-Ras mutation modulates the expression of major cell cycle regulatory proteins and disease prognosis in oral carcinoma
    • DOI 10.1038/modpathol.3800948, PII 3800948
    • Sathyan KM, Nalinnakumari KR, Kannan S. H-Ras mutation modulates the expression of major cell cycle regulatory proteins and disease prognosis in oral carcinoma. Modern Pathology 2007;20(11):1141-8. (Pubitemid 47609061)
    • (2007) Modern Pathology , vol.20 , Issue.11 , pp. 1141-1148
    • Sathyan, K.M.1    Nalinakumari, K.R.2    Kannan, S.3
  • 69
  • 70
    • 0029937141 scopus 로고    scopus 로고
    • Molecular changes in oral cancer may reflect aetiology and ethnic origin
    • Paterson IC, Eveson JW, Prime SS. Molecular changes in oral cancer may reflect aetiology and ethnic origin. Eur J Cancer B Oral Oncol 1996;32B(3):150-3.
    • (1996) Eur J Cancer B Oral Oncol , vol.32 B , Issue.3 , pp. 150-153
    • Paterson, I.C.1    Eveson, J.W.2    Prime, S.S.3
  • 71
    • 0021871265 scopus 로고
    • Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats
    • DOI 10.1038/315382a0
    • Zarbl H, Sukumar S, Arthur AV, Martin-Zanca D, Barbacid M. Direct mutagenesis of of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats. Nature 1985;315(6018):382-5. (Pubitemid 15031546)
    • (1985) Nature , vol.315 , Issue.6018 , pp. 382-385
    • Zarbl, H.1    Sukumar, S.2    Arthur, A.V.3
  • 72
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
    • Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 1986;322(6074):78-80. (Pubitemid 16061512)
    • (1986) Nature , vol.322 , Issue.6074 , pp. 78-80
    • Quintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 74
    • 33745366189 scopus 로고    scopus 로고
    • Influence of single nucleotide polymorphisms in H-Ras and cyclin D1 genes on oral cancer susceptibility
    • DOI 10.1016/j.oraloncology.2005.10.019, PII S1368837505003040
    • Sathyan KM, Nalinikumari KR, Abraham T, Kannan S. Influence of single nucleotide polymorphisms in H-RAS and cyclin D1 genes on oral cancer susceptibility. Oral Oncol 2006;42(6):607-13. (Pubitemid 43947667)
    • (2006) Oral Oncology , vol.42 , Issue.6 , pp. 607-613
    • Sathyan, K.M.1    Nalinakumari, K.R.2    Abraham, T.3    Kannan, S.4
  • 75
    • 0034002462 scopus 로고    scopus 로고
    • RAFTK/Pyk2-mediated cellular signalling
    • DOI 10.1016/S0898-6568(99)00076-5, PII S0898656899000765
    • Avraham H, Park SY, Schinkmann K, Avraham S. RAFTK/Pyk2-mediated cellular signalling. Cell Signal 2000;12(3):123-33. (Pubitemid 30126029)
    • (2000) Cellular Signalling , vol.12 , Issue.3 , pp. 123-133
    • Avraham, H.1    Park, S.-Y.2    Schinkmann, K.3    Avraham, S.4
  • 77
    • 0030464444 scopus 로고    scopus 로고
    • How Ras-related proteins talk to their effectors
    • DOI 10.1016/S0968-0004(96)10064-5, PII S0968000496100645
    • Wittinghofer A, Nassar N. How ras-related proteins talk to their effectors. Trends Biochem Sci 1996;21(12):488-91. (Pubitemid 27018818)
    • (1996) Trends in Biochemical Sciences , vol.21 , Issue.12 , pp. 488-491
    • Wittinghofer, A.1    Nassar, N.2
  • 79
    • 0027285320 scopus 로고
    • Structural requirements for the interaction of p21(ras) with GAP, exchange factors, and its biological effector target
    • Polakis P, McCormick F. Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target. J Biol Chem 1993;268(13):9157-60. (Pubitemid 23145950)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.13 , pp. 9157-9160
    • Polakis, P.1    McCormick, F.2
  • 80
    • 28844448182 scopus 로고    scopus 로고
    • Oncogenic PI3K deregulates transcription and translation
    • DOI 10.1038/nrc1753
    • Bader AG, Kang S, Zhao L, Vogt PK. Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer 2005;5(12):921-9. (Pubitemid 41766781)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.12 , pp. 921-929
    • Bader, A.G.1    Kang, S.2    Zhao, L.3    Vogt, P.K.4
  • 81
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • DOI 10.1038/nature04869, PII NATURE04869
    • Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signaling controls tumor cell growth. Nature 2006;441(7092):424-30. (Pubitemid 44050136)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 82
    • 45449092590 scopus 로고    scopus 로고
    • SnapShot: Ras Signaling
    • Cully M, Downward J. SnapShot: Ras Signaling. Cell 2008;133(7):1292.
    • (2008) Cell , vol.133 , Issue.7 , pp. 1292
    • Cully, M.1    Downward, J.2
  • 85
    • 0028958919 scopus 로고
    • Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro
    • James GL, Goldstein JL, Brown MS. Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro. J Biol Chem 1995;270(11):6221-6.
    • (1995) J Biol Chem , vol.270 , Issue.11 , pp. 6221-6226
    • James, G.L.1    Goldstein, J.L.2    Brown, M.S.3
  • 86
    • 24744465206 scopus 로고    scopus 로고
    • The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling: Role in FTI enhancement of taxane and tamoxifen anti-tumor activity
    • DOI 10.1074/jbc.M503763200
    • Basso AD, Mirza A, Liu G, Long BJ, Bishop WR, Kirschmeier P. The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen antitumor activity. J Biol Chem 2005;280(35):31101-8. (Pubitemid 41291845)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.35 , pp. 31101-31108
    • Basso, A.D.1    Mirza, A.2    Liu, G.3    Long, B.J.4    Bishop, W.R.5    Kirschmeier, P.6
  • 87
    • 0030916369 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors alter the prenylation and growth- stimulating function of RhoB
    • DOI 10.1074/jbc.272.25.15591
    • Lebowitz PF, Casey PJ, Prendergast GC, Thissen JA. Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB. J Biol Chem 1997;272(25):15591-4. (Pubitemid 27265524)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.25 , pp. 15591-15594
    • Lebowitz, P.F.1    Casey, P.J.2    Prendergast, G.C.3    Thissen, J.A.4
  • 88
    • 0025764049 scopus 로고
    • The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins
    • Hrycyna CA, Sapperstein SK, Clarke S, Michaelis S. The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins. EMBO J 1991;10(7):1699-709. (Pubitemid 21905637)
    • (1991) EMBO Journal , vol.10 , Issue.7 , pp. 1699-1709
    • Hrycyna, C.A.1    Sapperstein, S.K.2    Clarke, S.3    Michaelis, S.4
  • 89
    • 0026747866 scopus 로고
    • Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
    • Kato K, Cox AD, Hisaka MM, Graham SM, Buss JE, Der CJ. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. Proc Natl Acad Sci USA 1992;89(14):6403-7.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.14 , pp. 6403-6407
    • Kato, K.1    Cox, A.D.2    Hisaka, M.M.3    Graham, S.M.4    Buss, J.E.5    Der, C.J.6
  • 91
    • 0032515141 scopus 로고    scopus 로고
    • Reovirus therapy of tumors with activated Ras pathway
    • Coffey MC, Strong JE, Forsyth PA, Lee PW. Reovirus therapy of tumors with activated Ras pathway. Science 1998;282(5392):1332-4. (Pubitemid 28524498)
    • (1998) Science , vol.282 , Issue.5392 , pp. 1332-1334
    • Coffey, M.C.1    Strong, J.E.2    Forsyth, P.A.3    Lee, P.W.K.4
  • 92
    • 0029831041 scopus 로고    scopus 로고
    • Quantitative immunohistochemical analysis of transforming growth factor- alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck
    • DOI 10.1002/(SICI)1097-0142(19960915)78:6<1284::AID-CNCR17>3.0. CO;2-X
    • Rubin GJ, Melhem MF, Barnes EL, Tweardy DJ. Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck. Cancer 1996;78(6):1284-92. (Pubitemid 26303896)
    • (1996) Cancer , vol.78 , Issue.6 , pp. 1284-1292
    • Grandis, J.R.1    Melhem, M.F.2    Barnes, E.L.3    Tweardy, D.J.4
  • 93
    • 0041733629 scopus 로고    scopus 로고
    • Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area
    • DOI 10.1038/sj.bjc.6601171
    • Chen IH, Chang JT, Liao CT, Wang HM, Hsieh LL, Cheng AJ. Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area cancer prognosis. Br J Cancer 2003;89(4):681-6. (Pubitemid 37076173)
    • (2003) British Journal of Cancer , vol.89 , Issue.4 , pp. 681-686
    • Chen, I.-H.1    Chang, J.T.2    Liao, C.-T.3    Wang, H.-M.4    Hsieh, L.-L.5    Cheng, A.-J.6
  • 94
    • 0033800546 scopus 로고    scopus 로고
    • Defining a common region of DNA amplfication at 22q11.2-12 in head and neck squamous cell carcinomas by quantitative FISH analysis
    • Matsumura K, Iritani A, Enomoto S, Torikata C, Matsuyama S, Kurita A, et al. Defining a common region of DNA amplfication at 22q11.2-12 in head and neck squamous cell carcinomas by quantitative FISH analysis. Genes Chromosomes Cancer 2000;29(3):207-12.
    • (2000) Genes Chromosomes Cancer , vol.29 , Issue.3 , pp. 207-212
    • Matsumura, K.1    Iritani, A.2    Enomoto, S.3    Torikata, C.4    Matsuyama, S.5    Kurita, A.6
  • 95
    • 67650418218 scopus 로고    scopus 로고
    • EGFR protein overexpression and mutation in areca quid-associated oral cavity squamous cell carcinoma in Taiwan
    • Huang SF, Chuang WY, Chen IH, Liao CT, Wang HM, Hsieh LL. EGFR protein overexpression and mutation in areca quid-associated oral cavity squamous cell carcinoma in Taiwan. Head & Neck 2009;31(8):1068-77.
    • (2009) Head & Neck , vol.31 , Issue.8 , pp. 1068-1077
    • Huang, S.F.1    Chuang, W.Y.2    Chen, I.H.3    Liao, C.T.4    Wang, H.M.5    Hsieh, L.L.6
  • 97
    • 33750364266 scopus 로고    scopus 로고
    • PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma
    • DOI 10.1111/j.1349-7006.2006.00343.x
    • Kozaki K, Imoto I, Pimkhaokham A, Hasegawa S, Tsuda H, Omura K, et al. PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma. Cancer Sci 2006;97(12):1351-8. (Pubitemid 44614987)
    • (2006) Cancer Science , vol.97 , Issue.12 , pp. 1351-1358
    • Kozaki, K.-I.1    Imoto, I.2    Pimkhaokham, A.3    Hasegawa, S.4    Tsuda, H.5    Omura, K.6    Inazawa, J.7
  • 99
    • 13244265590 scopus 로고    scopus 로고
    • Frequent genetic and biochemical alteration of the PI3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma
    • Pedreo JMG, Carracedo DG, Pinto CM, Rodrigo ZapateroAH, JP NietoCS, et al. Frequent genetic and biochemical alteration of the PI3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma. Int J Cancer 2005;114(2):242-8.
    • (2005) Int J Cancer , vol.114 , Issue.2 , pp. 242-248
    • Pedreo, J.M.G.1    Carracedo, D.G.2    Pinto, C.M.3    Rodrigo, J.P.4    Zapatero, A.H.5    Nieto, C.S.6
  • 100
    • 0036836259 scopus 로고    scopus 로고
    • Inactivation of the PTEN gene by mutation, exonic deletion, and loss of transcript in human oral squamous cell carcinomas
    • Shin KH, Kim JM, Rho KS, Park KH, Oh JE, Min BM. Inactivation of the PTEN gene by mutation, exonic deletion, and loss of transcript in human oral squamous cell carcinomas. Int J Oncol 2002;21(5):997-1001.
    • (2002) Int J Oncol , vol.21 , Issue.5 , pp. 997-1001
    • Shin, K.H.1    Kim, J.M.2    Rho, K.S.3    Park, K.H.4    Oh, J.E.5    Min, B.M.6
  • 101
    • 0029610406 scopus 로고
    • Differential c-myc, c-jun, c-raf and p53 expression in squamous cell carcinoma of the head and neck: Implication in drug and radioresistance
    • DOI 10.1016/0964-1955(95)00045-3
    • Riva C, Lavieille JP, Reyt E, Brambilla E, Lunardi J, Brambilla C. Differential cmyc, c-jun, c-raf and p53 expression in squamous cell carcinoma of the head and neck: implication in drug and radioresistance. Eur J Cancer B Oral Oncol 1995;31B(6):384-91. (Pubitemid 26009168)
    • (1995) European Journal of Cancer Part B: Oral Oncology , vol.31 , Issue.6 , pp. 384-391
    • Riva, C.1    Lavieille, J.-P.2    Reyt, E.3    Brambilla, E.4    Lunardi, J.5    Brambilla, C.6
  • 103
    • 33644831522 scopus 로고    scopus 로고
    • A mutation in the common docking domain of ERK2 in a human cancer cell line, which was associated with its constitutive phosphorylation
    • Arvind R, Shimamoto H, Momose F, Amagasa T, Omura K, Tsuchida N. A mutation in the common docking domain of ERK2 in a human cancer cell line, which was associated with its constitutive phosphorylation. Int J Oncol 2005;27(6):1499-504.
    • (2005) Int J Oncol , vol.27 , Issue.6 , pp. 1499-1504
    • Arvind, R.1    Shimamoto, H.2    Momose, F.3    Amagasa, T.4    Omura, K.5    Tsuchida, N.6
  • 104
    • 54949130145 scopus 로고    scopus 로고
    • ERK2 CD domain mutation from a human cancer cell line enhanced anchorageindependent cell growth and abnormality in Drosophila
    • Mahalingam M, Arvind R, Ida H, Murugan AK, Yamaguchi M, Tsuchida N. ERK2 CD domain mutation from a human cancer cell line enhanced anchorageindependent cell growth and abnormality in Drosophila. Oncol Rep 2008;20(4):957-62.
    • (2008) Oncol Rep , vol.20 , Issue.4 , pp. 957-962
    • Mahalingam, M.1    Arvind, R.2    Ida, H.3    Murugan, A.K.4    Yamaguchi, M.5    Tsuchida, N.6
  • 105
    • 34249026448 scopus 로고    scopus 로고
    • Binding of Ras to Phosphoinositide 3-Kinase p110alpha Is Required for Ras- Driven Tumorigenesis in Mice
    • DOI 10.1016/j.cell.2007.03.051, PII S009286740700520X
    • Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, Nicke B, et al. Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice. Cell 2007;129(5):957-68. (Pubitemid 46802703)
    • (2007) Cell , vol.129 , Issue.5 , pp. 957-968
    • Gupta, S.1    Ramjaun, A.R.2    Haiko, P.3    Wang, Y.4    Warne, P.H.5    Nicke, B.6    Nye, E.7    Stamp, G.8    Alitalo, K.9    Downward, J.10
  • 106
    • 0032508517 scopus 로고    scopus 로고
    • Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
    • DOI 10.1074/jbc.273.37.24052
    • Yan J, Roy S, Apolloni A, Lane A, Hancock JF. Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J Biol Chem 1998;273(37):24052-6. (Pubitemid 28435747)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.37 , pp. 24052-24056
    • Yan, J.1    Roy, S.2    Apolloni, A.3    Lane, A.4    Hancock, J.F.5
  • 107
    • 70450195268 scopus 로고    scopus 로고
    • Are RAS mutations predictive markers of resistance to standard chemotherapy?
    • Loriot Y, Mordant P, Deutsch E, Olaussen KA, Soria JC. Are RAS mutations predictive markers of resistance to standard chemotherapy? Nat Rev Clin Oncol 2009;6(9):528-34.
    • (2009) Nat Rev Clin Oncol , vol.6 , Issue.9 , pp. 528-534
    • Loriot, Y.1    Mordant, P.2    Deutsch, E.3    Olaussen, K.A.4    Soria, J.C.5
  • 109
    • 68949205034 scopus 로고    scopus 로고
    • KRAS status and epidermal growth factor receptor expression as determinants for anti-EGFR therapies in salivary gland carcinomas
    • Dahse R, Driemel O, Schwarz S, Kromeyer-Hauschild K, Berndt A, Kosmehl H. KRAS status and epidermal growth factor receptor expression as determinants for anti-EGFR therapies in salivary gland carcinomas. Oral Oncol 2009;45(9):826-9.
    • (2009) Oral Oncol , vol.45 , Issue.9 , pp. 826-829
    • Dahse, R.1    Driemel, O.2    Schwarz, S.3    Kromeyer-Hauschild, K.4    Berndt, A.5    Kosmehl, H.6
  • 110
    • 67449113765 scopus 로고    scopus 로고
    • Methylation of RASSF1A, RASSF2A, and HIN-1 is associated with poor outcome after radiotherapy, but not surgery, in oral squamous cell carcinoma
    • Huang KH, Huang SF, Chen IH, Liao CT, Wang HM, Hsieh LL. Methylation of RASSF1A, RASSF2A, and HIN-1 is associated with poor outcome after radiotherapy, but not surgery, in oral squamous cell carcinoma. Clin Cancer Res 2009;15(12):4174-80.
    • (2009) Clin Cancer Res , vol.15 , Issue.12 , pp. 4174-4180
    • Huang, K.H.1    Huang, S.F.2    Chen, I.H.3    Liao, C.T.4    Wang, H.M.5    Hsieh, L.L.6
  • 111
    • 0026584304 scopus 로고
    • Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck
    • Rikimaru K, Tadokoro K, Yamamoto T, Enomoto S, Tsuchida N. Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck. Head Neck 1992;14(1):8-13.
    • (1992) Head Neck , vol.14 , Issue.1 , pp. 8-13
    • Rikimaru, K.1    Tadokoro, K.2    Yamamoto, T.3    Enomoto, S.4    Tsuchida, N.5
  • 112
    • 80054001986 scopus 로고    scopus 로고
    • Mutational analysis of PTEN/PIK3CA/AKT pathway in oral squamous cell carcinoma
    • Cohen Y, Goldenberg-Cohen N, Shalmon B, Shani T, Oren S, Amariglio N, et al. Mutational analysis of PTEN/PIK3CA/AKT pathway in oral squamous cell carcinoma. Oral Oncol 2011;47(10):946-50.
    • (2011) Oral Oncol , vol.47 , Issue.10 , pp. 946-950
    • Cohen, Y.1    Goldenberg-Cohen, N.2    Shalmon, B.3    Shani, T.4    Oren, S.5    Amariglio, N.6
  • 114
    • 0034142199 scopus 로고    scopus 로고
    • H-ras gene mutations in salivary gland mucoepidermoid carcinomas
    • DOI 10.1002/(SICI)1097-0142(20000201)88:3<518::AID-CNCR4>3.0.CO;2-W
    • Yoo J, Robinson RA. H-ras gene mutations in salivary gland mucoepidermoid carcinomas. Cancer 2000;88(3):518-23. (Pubitemid 30056923)
    • (2000) Cancer , vol.88 , Issue.3 , pp. 518-523
    • Yoo, J.1    Robinson, R.A.2
  • 115
    • 0030199087 scopus 로고    scopus 로고
    • Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma
    • Sakata K. Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma. J Oral Pathol Med 1996;25(6):302-7. (Pubitemid 26370060)
    • (1996) Journal of Oral Pathology and Medicine , vol.25 , Issue.6 , pp. 302-307
    • Sakata, K.1
  • 120
    • 0026719081 scopus 로고
    • Point mutations in the Ha-ras oncogene are detectable in formalin-fixed tissues of oral squamous cell carcinomas, but are infrequent in British cases
    • Warnakulasuriya KA, Chang SE, Johnson NW. Point mutations in the Ha-ras oncogene are detectable in formalin-fixed tissues of oral squamous cell carcinomas, but are infrequent in British cases. J Oral Pathol Med 1992;21(5):225-9.
    • (1992) J Oral Pathol Med , vol.21 , Issue.5 , pp. 225-229
    • Warnakulasuriya, K.A.1    Chang, S.E.2    Johnson, N.W.3
  • 121
    • 0027080366 scopus 로고
    • Analysis of ras oncogene mutations in human squamous cell carcinoma of the head and neck
    • DOI 10.1016/0960-7404(92)90043-K
    • Núñez F, Domínguez O, Coto E, Suárez-Nieto C, Pérez P, López-Larrea C. Analysis of ras oncogene mutations in human squamous cell carcinoma of the head and neck. Surg Oncol 1992;1(6):405-11. (Pubitemid 23018999)
    • (1992) Surgical Oncology , vol.1 , Issue.6 , pp. 405-411
    • Nunez, F.1    Dominguez, O.2    Coto, E.3    Suarez-Nieto, C.4    Perez, P.5    Lopez-Larrea, C.6
  • 122
    • 0026474705 scopus 로고
    • Prevalence of RAS oncogene mutation in head and neck carcinomas
    • Anderson JA, Irish JC, Ngan BY. Prevalence of RAS oncogene mutation in head and neck carcinomas. J Otolaryngol 1992;21(5):321-6.
    • (1992) J Otolaryngol , vol.21 , Issue.5 , pp. 321-326
    • Anderson, J.A.1    Irish, J.C.2    Ngan, B.Y.3
  • 124
    • 0026252608 scopus 로고
    • Point mutation of c-Ha-ras oncogene in oral cancers
    • Liu XF. Point mutation of c-Ha-ras oncogene in oral cancers. Zhonghua Kou Qiang Yi Xue Za Zhi 1991;26(6):326-8388.
    • (1991) Zhonghua Kou Qiang Yi Xue Za Zhi , vol.26 , Issue.6 , pp. 326-8388
    • Liu, X.F.1
  • 126
    • 0025237434 scopus 로고
    • Low incidence of ras oncogene activation in human squamous cell carcinomas
    • Rumsby G, Carter RL, Gusterson BA. Low incidence of ras oncogene activation in human squamous cell carcinomas. Br J Cancer 1990;61(3):365-8. (Pubitemid 20106006)
    • (1990) British Journal of Cancer , vol.61 , Issue.3 , pp. 365-368
    • Rumsby, G.1    Carter, R.L.2    Gusterson, B.A.3
  • 127
    • 0025063619 scopus 로고
    • Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas
    • Sheng ZM, Barrois M, Klijanienko J, Micheau C, Richard JM, Riou G. Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas. Br J Cancer 1990;62(3):398-404. (Pubitemid 20292835)
    • (1990) British Journal of Cancer , vol.62 , Issue.3 , pp. 398-404
    • Sheng, Z.M.1    Barrois, M.2    Klijanienko, J.3    Micheau, C.4    Richard, J.M.5    Riou, G.6
  • 128
    • 65849458558 scopus 로고    scopus 로고
    • Genome-wide massively parallel sequencing of formaldehyde fixed-paraffin embedded (FFPE) tumor tissues for copynumber and mutation-analysis
    • Schweiger MR, Kerick M, Timmermann B, Albrecht MW, Borodina T, Parkhomchuk D, et al. Genome-wide massively parallel sequencing of formaldehyde fixed-paraffin embedded (FFPE) tumor tissues for copynumber and mutation-analysis. PLoS One 2009;4(5):e5548.
    • (2009) PLoS One , vol.4 , Issue.5
    • Schweiger, M.R.1    Kerick, M.2    Timmermann, B.3    Albrecht, M.W.4    Borodina, T.5    Parkhomchuk, D.6
  • 129
    • 79957832926 scopus 로고    scopus 로고
    • KRAS mutation detection in paired frozen and formalin-fixed paraffin-embedded (ffpe) colorectal cancer tissues
    • Solassol J, Ramos J, Crapez E, Saifi M, Mangé A, Vianès E, et al. KRAS mutation detection in paired frozen and formalin-fixed paraffin-embedded (ffpe) colorectal cancer tissues. Int J Mol Sci 2011;12(5):3191-204.
    • (2011) Int J Mol Sci , vol.12 , Issue.5 , pp. 3191-3204
    • Solassol, J.1    Ramos, J.2    Crapez, E.3    Saifi, M.4    Mangé, A.5    Vianès, E.6
  • 130
    • 34249789581 scopus 로고    scopus 로고
    • EGFR and K-ras mutation analysis in non-small cell lung cancer: Comparison of paraffin embedded versus frozen specimens
    • Gallegos Ruiz MI, Floor K, Rijmen F, Grünberg K, Rodriguez JA, Giaccone G. EGFR and K-ras mutation analysis in non-small cell lung cancer: comparison of paraffin embedded versus frozen specimens. Cell Oncol 2007;29(3):257-64. (Pubitemid 46855706)
    • (2007) Cellular Oncology , vol.29 , Issue.3 , pp. 257-264
    • Gallegos, R.M.I.1    Floor, K.2    Rijmen, F.3    Grunberg, K.4    Rodriguez, J.A.5    Giaccone, G.6
  • 132
    • 77954380684 scopus 로고    scopus 로고
    • Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: Diagnostic and clinical implications
    • Tsiatis AC, Norris-Kirby A, Rich RG, Hafez MJ, Gocke CD, Eshleman JR, et al. Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications. J Mol Diagn 2010;12(4):425-32.
    • (2010) J Mol Diagn , vol.12 , Issue.4 , pp. 425-432
    • Tsiatis, A.C.1    Norris-Kirby, A.2    Rich, R.G.3    Hafez, M.J.4    Gocke, C.D.5    Eshleman, J.R.6
  • 133
    • 80054839029 scopus 로고    scopus 로고
    • A comparison of parallel pyrosequencing and sanger clone-based sequencing and its impact on the characterization of the genetic diversity of HIV-1
    • Liang B, Luo M, Scott-Herridge J, Semeniuk C, Mendoza M, Capina R, et al. A comparison of parallel pyrosequencing and sanger clone-based sequencing and its impact on the characterization of the genetic diversity of HIV-1. PLoS One 2011;6(10):e26745.
    • (2011) PLoS One , vol.6 , Issue.10
    • Liang, B.1    Luo, M.2    Scott-Herridge, J.3    Semeniuk, C.4    Mendoza, M.5    Capina, R.6
  • 134
    • 65649128973 scopus 로고    scopus 로고
    • Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer
    • Yu J, Kane S, Wu J, Benedettini E, Li D, Reeves C, et al. Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer. Clin Cancer Res 2009;15(9):3023-8.
    • (2009) Clin Cancer Res , vol.15 , Issue.9 , pp. 3023-3028
    • Yu, J.1    Kane, S.2    Wu, J.3    Benedettini, E.4    Li, D.5    Reeves, C.6
  • 135
    • 71549122009 scopus 로고    scopus 로고
    • Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors
    • Capper D, Weissert S, Balss J, Habel A, Meyer J, Jäger D, et al. Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors. Brain Pathol 2010;20(1):245-54.
    • (2010) Brain Pathol , vol.20 , Issue.1 , pp. 245-254
    • Capper, D.1    Weissert, S.2    Balss, J.3    Habel, A.4    Meyer, J.5    Jäger, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.