Engineering discoidal polymeric nanoconstructs with enhanced magneto-optical properties for tumor imaging

Biomaterials

Volumn 34, Issue 21, 2013, Pages 5402-5410

  Key, Jaehong ^a   Aryal, Santosh ^a   Gentile, Francesco ^b   Ananta, Jeyarama S ^a   Zhong, Meng ^a   Landis, Melissa D ^a   Decuzzi, Paolo ^a,b  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Multi modal imaging; Nanoparticle shape; Polymeric nanoparticles; Relaxivity

Indexed keywords

IRON OXIDE NANOPARTICLE; MAGNETOOPTICAL PROPERTIES; MULTI-MODAL IMAGING; NANOPARTICLE SHAPE; POLY(LACTIC ACID-CO-GLYCOLIC ACID); POLYETHYLENE GLYCOL (PEG); POLYMERIC NANOPARTICLES; RELAXIVITY;

ACRYLIC MONOMERS; EMULSIFICATION; NANOPARTICLES; OPTICAL PROPERTIES; PARAMAGNETISM; SURFACE PROPERTIES; SYNTHESIS (CHEMICAL);

POLYMERS;

DISCOIDAL POLYMERIC NANOCONSTRUCT; IRON OXIDE; MACROGOL; METHACRYLIC ACID; NANOPARTICLE; POLYGLACTIN; RHODAMINE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; BIOAVAILABILITY; BIODEGRADABILITY; CELL SURVIVAL; CENTRIFUGATION; CONTROLLED STUDY; CYTOTOXICITY; DISSOLUTION; ENCAPSULATION; HUMAN; HUMAN CELL; HYDRODYNAMICS; HYDROGEL; HYDROLYSIS; HYDROLYSIS KINETICS; IN VIVO STUDY; MOUSE; NANOFABRICATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; POLYMERIZATION; PRIORITY JOURNAL; RELAXATION TIME; ZETA POTENTIAL;

ANIMALS; CELL DEATH; DIAGNOSTIC IMAGING; HELA CELLS; HUMANS; LACTIC ACID; MAGNETIC PHENOMENA; METHACRYLATES; MICE; MICE, SCID; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; NANOTECHNOLOGY; NEOPLASMS; OPTICAL PHENOMENA; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; RHODAMINES;

EID: 84877015120     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.03.078     Document Type: Article

References (50)

1. Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 2005, 5:161-171.
2. Peer D., Karp J.M., Hong S., Farokhzad O.C., Margalit R., Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2007, 2:751-760.
3. Gil P.R., Parak W.J. Composite nanoparticles take aim at cancer. ACS Nano 2008, 2:2200-2205.
4. Farokhzad O.C., Langer R. Impact of nanotechnology on drug delivery. ACS Nano 2009, 3:16-20.
5. Matsumura Y., Maeda H. Anew concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986, 46:6387-6392.
6. Maeda H., Matsumura Y. EPR effects. Adv Drug Deliv Rev 2011, 63.
7. Jain R.K., Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 2010, 7:653-664.
8. Torchilin V. Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev 2011, 63:131-135.
9. Petersen A.L., Hansen A.E., Gabizon A., Andresen T.L. Liposome imaging agents in personalized medicine. Adv Drug Deliv Rev 2012, 64:1417-1435.
10. Moghimi S.M., Hunter A.C., Andresen T.L. Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective. Annu Rev Pharmacol Toxicol 2012, 52:481-503.
11. Auerbach R. Vascular endothelial cell differentiation: organ-specificity and selective affinities as the basis for developing anti-cancer strategies. Int J Radiat Biol 1991, 60:1-10.
12. Pasqualini R., Arap W., McDonald D.M. Probing the structural and molecular diversity of tumor vasculature. Trends Mol Med 2002, 8:563-571.
13. Sergeeva A., Kolonin M.G., Molldrem J.J., Pasqualini R., Arap W. Display technologies: application for the discovery of drug and gene delivery agents. Adv Drug Deliv Rev 2006, 58:1622-1654.
14. Sengupta S., Eavarone D., Capila I., Zhao G., Watson N., Kiziltepe T., et al. Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature 2005, 436:568-572.
15. Huang X., Peng X., Wang Y., Shin D.M., El-Sayed M.A., Nie S. Areexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands. ACS Nano 2010, 4:5887.
16. Decuzzi P., Pasqualini R., Arap W., Ferrari M. Intravascular delivery of particulate systems: does geometry really matter?. Pharm Res 2009, 26:235-243.
17. Mitragotri S., Lahann J. Physical approaches to biomaterial design. Nat Mater 2009, 8:15-23.
18. Lee S.Y., Ferrari M., Decuzzi P. Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows. Nanotechnology 2009, 20:495101.
19. Tao L., Hu W., Liu Y., Huang G., Sumer B.D., Gao J. Shape-specific polymeric nanomedicine: emerging opportunities and challenges. Exp Biol Med (Maywood) 2011, 236:20-29.
20. Geng Y., Dalhaimer P., Cai S., Tsai R., Tewari M., Minko T., et al. Shape effects of filaments versus spherical particles in flow and drug delivery. Nat Nanotechnol 2007, 2:249-255.
21. Muro S., Garnacho C., Champion J.A., Leferovich J., Gajewski C., Schuchman E.H., et al. Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Mol Ther 2008, 16:1450-1458.
22. Decuzzi P., Ferrari M. The adhesive strength of non-spherical particles mediated by specific interactions. Biomaterials 2006, 27:5307-5314.
23. Adriani G., de Tullio M.D., Ferrari M., Hussain F., Pascazio G., Liu X., et al. The preferential targeting of the diseased microvasculature by disk-like particles. Biomaterials 2012, 33:5504-5513.
24. van de Ven A.L., Kim P., Haley O.H., Fakhoury J.R., Adriani G., Schmulen J., et al. Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution. JControl Release 2012, 158:148-155.
25. Gentile F., Chiappini C., Fine D., Bhavane R.C., Peluccio M.S., Cheng M.M.-C., et al. The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows. JBiomech 2008, 41:2312-2318.
26. Lee S.-Y., Ferrari M., Decuzzi P. Design of bio-mimetic particles with enhanced vascular interaction. JBiomech 2009, 42:1885-1890.
27. Graf N., Bielenberg D.R., Kolishetti N., Muus C., Banyard J., Farokhzad O.C., et al. αvβ3 Integrin-targeted PLGA-PEG nanoparticles for enhanced anti-tumor efficacy of a Pt(IV) prodrug. ACS Nano 2012, 6:4530-4539.
28. Nehilla B.J., Allen P.G., Desai T.A. Surfactant-free, drug-quantum-dot coloaded poly(lactide-co-glycolide) nanoparticles: towards multifunctional nanoparticles. ACS Nano 2008, 2:538-544.
29. Park H., Yang J., Lee J., Haam S., Choi I.-H., Yoo K.-H. Multifunctional nanoparticles for combined doxorubicin and photothermal treatments. ACS Nano 2009, 3:2919-2926.
30. Tanaka T., Decuzzi P., Cristofanilli M., Sakamoto J., Tasciotti E., Robertson F., et al. Nanotechnology for breast cancer therapy. Biomed Microdevices 2009, 11:49-63.
31. Rolland J.P., Maynor B.W., Euliss L.E., Exner A.E., Denison G.M., DeSimone J.M. Direct fabrication and harvesting of monodisperse, shape-specific nanobiomaterials. JAm Chem Soc 2005, 127:10096-10100.
32. Champion J.A., Mitragotri S. Role of target geometry in phagocytosis. Proc Natl Acad Sci U S A 2006, 103:4930-4934.
33. Acharya G., Shin C.S., McDermott M., Mishra H., Park H., Kwon I.C., et al. The hydrogel template method for fabrication of homogeneous nano/microparticles. JControl Release 2010, 141:314-319.
34. Tasciotti E., Liu X., Bhavane R., Plant K., Leonard A.D., Price B.K., et al. Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications. Nat Nanotechnol 2008, 3:151-157.
35. Merkel T.J., Chen K., Jones S.W., Pandya A.A., Tian S., Napier M.E., et al. The effect of particle size on the biodistribution of low-modulus hydrogel PRINT particles. JControl Release 2012, 162:37-44.
36. Merkel T.J., Jones S.W., Herlihy K.P., Kersey F.R., Shields A.R., Napier M., et al. Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles. Proc Natl Acad Sci U S A 2011, 108:586-591.
37. Acharya G., Shin C.S., Vedantham K., McDermott M., Rish T., Hansen K., et al. Astudy of drug release from homogeneous PLGA microstructures. JControl Release 2010, 146:201-206.
38. Li X., Lewis M.T., Huang J., Gutierrez C., Osborne C.K., Wu M.-F., et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. JNatl Cancer Inst 2008, 100:672-679.
39. Creighton C.J., Li X., Landis M., Dixon J.M., Neumeister V.M., Sjolund A., et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A 2009, 106:13820-13825.
40. DeOme K., Medina D. Anew approach to mammary tumorigenesis in rodents. Cancer 1969, 24:1255-1258.
41. Landis M.D., Lehmann B.D., Pietenpol J.A., Chang J.C. Patient-derived breast tumor xenografts facilitating personalized cancer therapy. Breast Cancer Res 2013, 15:201.
42. Anderson J.M., Shive M.S. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 2012.
43. Harris J.M., Chess R.B. Effect of pegylation on pharmaceuticals. Nat Rev Drug Discov 2003, 2:214-221.
44. Laurent S., Forge D., Port M., Roch A., Robic C., Vander Elst L., et al. Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem Rev 2008, 108:2064-2110.
45. McCarthy J.R., Weissleder R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev 2008, 60:1241-1251.
46. Weinstein J.S., Varallyay C.G., Dosa E., Gahramanov S., Hamilton B., Rooney W.D., et al. Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a review. JCereb Blood Flow Metab 2009, 30:15-35.
47. Paquet C., de Haan H.W., Leek D.M., Lin H.-Y., Xiang B., Tian G., et al. Clusters of superparamagnetic iron oxide nanoparticles encapsulated in a hydrogel: a particle architecture generating a synergistic enhancement of the T2 relaxation. ACS Nano 2011, 5:3104-3112.
48. Roca A.G., Veintemillas-Verdaguer S., Port M., Robic C., Serna C.J., Morales M.P. Effect of nanoparticle and aggregate size on the relaxometric properties of MR contrast agents based on high quality magnetite nanoparticles. JPhys Chem B 2009, 113:7033-7039.
49. Ananta J.S., Godin B., Sethi R., Moriggi L., Liu X., Serda R.E., et al. Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast. Nat Nanotechnol 2010, 5:815-821.
50. Sethi R., Ananta J.S., Karmonik C., Zhong M., Fung S.H., Liu X., et al. Enhanced MRI relaxivity of Gd3+-based contrast agents geometrically confined within porous nanoconstructs. Contrast Media Mol Imaging 2012, 7:501-508.