A Conus regularis conotoxin with a novel eight-cysteine framework inhibits CaV2.2 channels and displays an anti-nociceptive activity

Marine Drugs

Volumn 11, Issue 4, 2013, Pages 1188-1202

  Bernaĺdez, Johanna ^a   Román Gonźalez, Sergio A ^b   Martińez, Oscar ^a   Jimeńez, Samanta ^a   Vivas, Oscar ^c   Arenas, Isabel ^c   Corzo, Gerardo ^d   Arreguiń, Roberto ^b   García, David E ^c   Possani, Lourival D ^d   Licea, Alexei ^a  

^a CENTRO DE INVESTIGACIÓN CIENTÍFICA Y DE EDUCACIÓN SUPERIOR DE ENSENADA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d INSTITUTO DE CIENCIAS FÍSICAS   (Mexico)

Author keywords

Calcium channel; Conus regularis; Eight cysteine toxin and conotoxins; Nociceptive

Indexed keywords

AMINO ACID; CALCIUM CHANNEL; CONOTOXIN; CONUS REGULARIS CONOTOXIN; CYSTEINE; LYSINE; PROTEIN; RSXXIVA PROTEIN; TRIFLUOROACETIC ACID; TYROSINE; UNCLASSIFIED DRUG; VENOM;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTINOCICEPTION; AQUEOUS SOLUTION; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; HOMOGENATE; MALE; MASS SPECTROMETRY; MEXICO; NONHUMAN; PATCH CLAMP; PROTEIN PURIFICATION; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SUPERIOR CERVICAL GANGLION; THERMAL STIMULATION;

CONUS REGULARIS;

EID: 84876989470     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md11041188     Document Type: Article

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