Insulin prevents mitochondrial generation of H2O2 in rat brain

Experimental Neurology

Volumn 247, Issue , 2013, Pages 66-72

  Muller, Alexandre Pastoris ^a   Haas, Clarissa Branco ^a   Camacho Pereira, Juliana ^b   Brochier, Andressa Wigner ^a   Gnoatto, Jussânia ^a   Zimmer, Eduardo Rigon ^a   de Souza, Diogo Onofre ^a   Galina, Antonio ^b   Portela, Luis Valmor ^a  

^a Instituto de Ciencias Biologicas e da Saude Pontifical Catholic University of Minas Gerais   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Brain metabolism; H2O2 production; Insulin signaling; Mitochondria

Indexed keywords

GLUCOSE; HYDROGEN PEROXIDE; INSULIN; LY 290042; OLIGOMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PYRUVIC ACID; ROTENONE; SODIUM; SUCCINIC ACID; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; EMBRYO; HORMONE ACTION; MALE; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOLECULAR INTERACTION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPTOSOME;

BRAIN METABOLISM; H(2)O(2) PRODUCTION; INSULIN SIGNALING; MITOCHONDRIA;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; GLUTAMIC ACID; HYDROGEN PEROXIDE; INSULIN; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEURONS; OXIDANTS; OXYGEN CONSUMPTION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SYNAPTOSOMES; TIME FACTORS;

EID: 84876977815     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.03.007     Document Type: Article

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