Morphine withdrawal produces ERK-dependent and ERK-independent epigenetic marks in neurons of the nucleus accumbens and lateral septum

Neuropharmacology

Volumn 70, Issue , 2013, Pages 168-179

  Ciccarelli, Alessandro ^a   Calza, Arianna ^c   Santoru, Francesca ^c   Grasso, Fabrizio ^a   Concas, Alessandra ^c,d   Sassoè Pognetto, Marco ^a,b   Giustetto, Maurizio ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b National Institute of Neuroscience   (Italy)

^c UNIVERSITY OF CAGLIARI   (Italy)

^d CNR   (Italy)

Author keywords

Epigenetics; ERK; MeCP2; Molecular cellular neurobiology; Neuroanatomy; Opioids; Signal transduction

Indexed keywords

ARGININE; CYTOSKELETON PROTEIN; HISTONE H3; LYSINE; METHYL CPG BINDING PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; NALOXONE; PHOSPHOPROTEIN; PROTEIN ARC; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSFORMATION; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DNA MODIFICATION; ENZYME ACTIVATION; ENZYME LOCALIZATION; EPIGENETICS; GENE EXPRESSION; GENETIC MARKER; HEREDITY; HISTONE ACETYLATION; HISTONE MODIFICATION; IMMEDIATE EARLY GENE; IMMUNOREACTIVITY; IN VIVO STUDY; LATERAL SEPTUM; LIMBIC SYSTEM; MALE; MORPHINE ADDICTION; NERVE CELL; NEUROANATOMY; NONHUMAN; NUCLEUS ACCUMBENS; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; WITHDRAWAL SYNDROME;

ACETYLATION; AMINOACETONITRILE; ANIMALS; CYTOSKELETAL PROTEINS; EPIGENESIS, GENETIC; GENE EXPRESSION; HISTONES; MALE; MAP KINASE SIGNALING SYSTEM; METHYL-CPG-BINDING PROTEIN 2; MORPHINE; NALOXONE; NERVE TISSUE PROTEINS; NEURONS; NUCLEUS ACCUMBENS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FOS; RATS; SEPTAL NUCLEI; SIGNAL TRANSDUCTION; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84876973876     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.12.010     Document Type: Article

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