Peripubertal-onset but not adult-onset obesity increases IGF-I and drives development of lean mass, which may lessen the metabolic impairment in adult obesity

American Journal of Physiology - Endocrinology and Metabolism

Volumn 303, Issue 9, 2012, Pages

  Cordoba Chacon, Jose ^a,b   Gahete, Manuel D ^a,b   Pozo Salas, Ana I ^a   Moreno Herrera, Antonio ^a   Castaño, Justo P ^a   Kineman, Rhonda D ^b   Luque, Raúl M ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

Age at onset of obesity; Childhood obesity; Insulin like growth factor type I

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN; GLUCOSE; INSULIN; SOMATOMEDIN C;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; DISEASE SEVERITY; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; GROUPS BY AGE; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LEAN BODY WEIGHT; LIPID DIET; LOW FAT DIET; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; ONSET AGE; PRIORITY JOURNAL; PUBERTY; REAL TIME POLYMERASE CHAIN REACTION; WEIGHT GAIN;

ADRENOCORTICOTROPIC HORMONE; AGING; ANIMALS; BODY COMPOSITION; CORTICOSTERONE; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; GLUCOSE INTOLERANCE; HYPERGLYCEMIA; HYPERINSULINISM; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; MUSCLE DEVELOPMENT; OBESITY; RANDOM ALLOCATION; SEVERITY OF ILLNESS INDEX; SEXUAL DEVELOPMENT;

EID: 84868329498     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00340.2012     Document Type: Article

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