Circulating IGF-1 and its role in cancer: Lessons from the IGF-1 gene deletion (LID) mouse

Novartis Foundation Symposium

Volumn 262, Issue , 2004, Pages 3-18

  Yakar, Shoshana ^a   Pennisi, Patricia ^a   Zhao, Hong ^a   Zhang, Yang ^a   LeRoith, Derek ^a   De Meyts, ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C;

ANIMAL; GENE DELETION; GENETICS; LIVER; METABOLISM; MOUSE; MOUSE MUTANT; NEOPLASM; REVIEW;

ANIMALS; GENE DELETION; INSULIN-LIKE GROWTH FACTOR I; LIVER; MICE; MICE, KNOCKOUT; NEOPLASMS;

EID: 16544382555     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (22)

1. Abramovitch S, Glaser T, Ouchi T, Werner H 2003 BRCA1-Sp1 interactions in transcriptional regulation of the IGF-1R gene. FEBS Lett 541:149-154
2. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ 2003 Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348:1625-1638
3. Chan JM, Stampfer MJ, Giovannucci E et al 1998 Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 279:563-566
4. Dunn SE, Kari FW, French J et al 1997 Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res 57:4667-4672
5. Gapstur SM, Gann PH, Colangelo LA et al 2001 Postload plasma glucose concentration and 27-year prostate cancer mortality (United States). Cancer Causes Control 12:763-772
6. Hankinson SE, Willett WC, Colditz GA et al 1998 Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 351:1393-1396
7. Levine W, Dyer AR, Shekelle RB, Schoenberger JA, Stamler J 1990 Post-load plasma glucose and cancer mortality in middle-aged men and women. 12-year follow-up findings of the Chicago Heart Association Detection Project in Industry. Am J Epidemiol 131:254-262
8. Ma J, Pollak MN, Giovannucci E et al 1999 Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 91:620-625
9. Pollak M, Blouin MJ, Zhang JC, Kopchick JJ 2001 Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist. Br J Cancer 85:428-430
10. Ragozzino M, Melton LJ 3rd, Chu CP, Palumbo PJ 1982 Subsequent cancer risk in the incidence cohort of Rochester, Minnesota, residents with diabetes mellitus. J Chronic Dis 35:13-19
11. Schoen RE, Tangen CM, Kuller LH et al 1999 Increased blood glucose and insulin, body size, and incident colorectal cancer. J Natl Cancer Inst 91:1147-1154
12. Stengard JH, Tuomilehto J, Pekkanen J et al 1992 Diabetes mellitus, impaired glucose tolerance and mortality among elderly men: the Finnish cohorts of the Seven Countries Study. Diabetologia 35:760-765
13. Thompson MM, Garland C, Barrett-Connor E, Khaw KT, Friedlander NJ, Wingard DL 1989 Heart disease risk factors, diabetes, and prostatic cancer in an adult community. Am J Epidemiol 129:511-517
14. Werner H, Re GG, Drummond IA et al 1993 Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product. Proc Natl Acad Sci USA 90:5828-5832
15. Werner H, Karnieli E, Rauscher FJ, LeRoith D 1996 Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc Natl Acad Sci USA 93:8318-8323
16. Will JC, Galuska DA, Vinicor F, Calle EE 1998 Colorectal cancer: another complication of diabetes mellitus? Am J Epidemiol 147:816-825
17. Wu Y, Yakar S, Ling Z, Henninhausen L, LeRoith D 2002 Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis. Cancer Res 62:1030-1035
18. Wu Y, Cui K, Miyoshi K, Hennighausen L et al 2003 Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors. Cancer Res 63:4384-4388
19. Yakar S, Liu JL, Stannard B et al 1999 Normal growth and development in the absence of hepatic insulin-like growth factor I. Proc Natl Acad Sci USA 96:7324-7329
20. Yakar S, Liu JL, Fernandez AM et al 2001 Liver-specific IGF-1 gene deletion leads to muscle insulin insensitivity. Diabetes 50:1110-1118
21. Yang XF, Beamer WG, Huynh H, Pollak M 1996 Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation. Cancer Res 56:1509-1511
22. Yu H, Spitz MR, Mistry J, Gu J, Hong WK, Wu X 1999 Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J Natl Cancer Inst 91:151-156