TCreERT2, a Transgenic Mouse Line for Temporal Control of Cre-Mediated Recombination in Lineages Emerging from the Primitive Streak or Tail Bud

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Anderson, Matthew J ^a   Naiche, L A ^a   Wilson, Catherine P ^a   Elder, Cindy ^a   Swing, Deborah A ^a   Lewandoski, Mark ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CRE RECOMBINASE; TAMOXIFEN; ANTIESTROGEN; BRACHYURY PROTEIN; FETOPROTEIN; T BOX TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; FEMALE; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENETIC MANIPULATION; GENETIC RECOMBINATION; GENETIC VARIABILITY; LOSS OF FUNCTION MUTATION; MALE; MESODERM; MOUSE; NONHUMAN; PRIMITIVE STREAK; PROMOTER REGION; TCREERT2 MOUSE; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; CYTOLOGY; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

MUS MUSCULUS;

ANIMALS; ESTROGEN ANTAGONISTS; FEMALE; FETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PRIMITIVE STREAK; RECOMBINATION, GENETIC; T-BOX DOMAIN PROTEINS; TAMOXIFEN;

EID: 84876965033     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062479     Document Type: Article

References (43)

1. Branda CS, Dymecki SM, (2004) Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Developmental cell 6: 7-28.
2. Lewandoski M, (2001) Conditional control of gene expression in the mouse. Nature reviews Genetics 2: 743-755.
3. Lewandoski M (2007) Analysis of mouse development with conditional mutagenesis. Handbook of experimental pharmacology: 235-262.
4. Guan C, Ye C, Yang X, Gao J, (2010) A review of current large-scale mouse knockout efforts. Genesis 48: 73-85.
5. Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni-Underwood S, et al. (2005) Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 132: 3859-3871.
6. Clements D, Taylor HC, Herrmann BG, Stott D, (1996) Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation. Mechanisms of development 56: 139-149.
7. Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP, (1999) T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes & development 13: 3185-3190.
8. Galceran J, Hsu SC, Grosschedl R, (2001) Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression. Proceedings of the National Academy of Sciences of the United States of America 98: 8668-8673.
9. Cambray N, Wilson V, (2002) Axial progenitors with extensive potency are localised to the mouse chordoneural hinge. Development 129: 4855-4866.
10. Kumar A, Lualdi M, Lewandoski M, Kuehn MR, (2008) Broad mesodermal and endodermal deletion of Nodal at postgastrulation stages results solely in left/right axial defects. Developmental dynamics: an official publication of the American Association of Anatomists 237: 3591-3601.
11. Aggarwal VS, Carpenter C, Freyer L, Liao J, Petti M, et al. (2010) Mesodermal Tbx1 is required for patterning the proximal mandible in mice. Developmental biology 344: 669-681.
12. Arnold SJ, Hofmann UK, Bikoff EK, Robertson EJ, (2008) Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development 135: 501-511.
13. Aulehla A, Wiegraebe W, Baubet V, Wahl MB, Deng C, et al. (2008) A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nature cell biology 10: 186-193.
14. Braunstein EM, Monks DC, Aggarwal VS, Arnold JS, Morrow BE, (2009) Tbx1 and Brn4 regulate retinoic acid metabolic genes during cochlear morphogenesis. BMC developmental biology 9: 31.
15. Di-Poi N, Koch U, Radtke F, Duboule D, (2010) Additive and global functions of HoxA cluster genes in mesoderm derivatives. Developmental biology 341: 488-498.
16. Dunty WC Jr, Biris KK, Chalamalasetty RB, Taketo MM, Lewandoski M, et al. (2008) Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development 135: 85-94.
17. Kitagaki J, Ueda Y, Chi X, Sharma N, Elder CM, et al. (2011) FGF8 is essential for formation of the ductal system in the male reproductive tract. Development 138: 5369-5378.
18. Liao J, Aggarwal VS, Nowotschin S, Bondarev A, Lipner S, et al. (2008) Identification of downstream genetic pathways of Tbx1 in the second heart field. Developmental biology 316: 524-537.
19. MacDonald ST, Bamforth SD, Chen CM, Farthing CR, Franklyn A, et al. (2008) Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency. Cardiovascular research 79: 448-457.
20. Naiche LA, Holder N, Lewandoski M, (2011) FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis. Proceedings of the National Academy of Sciences of the United States of America 108: 4018-4023.
21. Tzchori I, Day TF, Carolan PJ, Zhao Y, Wassif CA, et al. (2009) LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth. Development 136: 1375-1385.
22. Verheyden JM, Lewandoski M, Deng C, Harfe BD, Sun X, (2005) Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development 132: 4235-4245.
23. Wahl MB, Deng C, Lewandoski M, Pourquie O, (2007) FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development 134: 4033-4041.
24. Yi L, Domyan ET, Lewandoski M, Sun X, (2009) Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung. Developmental dynamics: an official publication of the American Association of Anatomists 238: 123-137.
25. Chalamalasetty RB, Dunty WC Jr, Biris KK, Ajima R, Iacovino M, et al. (2011) The Wnt3a/beta-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program. Nature communications 2: 390.
26. Zhang Z, O'Rourke JR, McManus MT, Lewandoski M, Harfe BD, et al. (2011) The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning. Developmental biology 351: 254-265.
27. Feil S, Valtcheva N, Feil R, (2009) Inducible Cre mice. Methods in molecular biology 530: 343-363.
28. Hayashi S, McMahon AP, (2002) Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Developmental biology 244: 305-318.
29. Feil R, Wagner J, Metzger D, Chambon P, (1997) Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochemical and biophysical research communications 237: 752-757.
30. Soriano P, (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nature genetics 21: 70-71.
31. Zervas M, Millet S, Ahn S, Joyner AL, (2004) Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron 43: 345-357.
32. Tam PP, (1981) The control of somitogenesis in mouse embryos. Journal of embryology and experimental morphology 65Suppl: 103-128.
33. Gomez C, Ozbudak EM, Wunderlich J, Baumann D, Lewis J, et al. (2008) Control of segment number in vertebrate embryos. Nature 454: 335-339.
34. Correia KM, Conlon RA, (2000) Surface ectoderm is necessary for the morphogenesis of somites. Mech Dev 91: 19-30.
35. Mansouri A, Yokota Y, Wehr R, Copeland NG, Jenkins NA, et al. (1997) Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system. Developmental dynamics: an official publication of the American Association of Anatomists 210: 53-65.
36. Neidhardt LM, Kispert A, Herrmann BG, (1997) A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system. Development Genes and Evolution 207: 330-339.
37. Long MA, Rossi FM, (2009) Silencing inhibits Cre-mediated recombination of the Z/AP and Z/EG reporters in adult cells. PLoS One 4: e5435.
38. Vooijs M, Jonkers J, Berns A, (2001) A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent. EMBO Rep 2: 292-297.
39. Wehn AK, Gallo PH, Chapman DL, (2009) Generation of transgenic mice expressing Cre recombinase under the control of the Dll1 mesoderm enhancer element. Genesis 47: 309-313.
40. Jukkola T, Trokovic R, Maj P, Lamberg A, Mankoo B, et al. (2005) Meox1Cre: a mouse line expressing Cre recombinase in somitic mesoderm. Genesis 43: 148-153.
41. Peter Lopez T, Fan CM (2011) A transgenic Tbx6;CreER(T2) line for inducible gene manipulation in the presomitic mesoderm. Genesis.
42. Lewandoski M, Meyers EN, Martin GR, (1997) Analysis of Fgf8 gene function in vertebrate development. Cold Spring Harbor symposia on quantitative biology 62: 159-168.
43. Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, et al. (2001) Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128: 1253-1264.