Development of a Quantitative Multi-Mycotoxin Method in Rice, Maize, Wheat and Peanut Using UPLC-MS/MS

Food Analytical Methods

Volumn 6, Issue 3, 2013, Pages 727-736

  Tang, Yu Y ^a   Lin, Hsu Y ^a   Chen, Ying C ^a   Su, Wei T ^a   Wang, Si C ^a   Chiueh, Lih C ^a   Shin, Yang C ^a  

^a Executive Yuan   (Taiwan)

Author keywords

Grains; Liquid chromatography tandem mass spectrometry; Mycotoxin; Synchronised analysis

Indexed keywords

AVERAGE RECOVERY RATE; COEFFICIENT OF VARIATION; IMMUNOAFFINITY COLUMNS; LIMITS OF QUANTIFICATION; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY (LC MS/MS); LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MYCOTOXIN; SYNCHRONISED ANALYSIS;

ANTIGEN-ANTIBODY REACTIONS; DEIONIZED WATER; GRAIN (AGRICULTURAL PRODUCT); HEALTH RISKS; INTERFERENCE SUPPRESSION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; OILSEEDS; SEPARATION; SUBSTRATES;

TOXICITY;

ARACHIS HYPOGAEA; ASPERGILLUS; FUNGI; FUSARIUM; PENICILLIUM; TRITICUM AESTIVUM; ZEA MAYS;

EID: 84876958674     PISSN: 19369751     EISSN: 1936976X     Source Type: Journal    
DOI: 10.1007/s12161-012-9473-8     Document Type: Article

References (30)

1. Anderson B, Frisvad JC (2004) Natural occurrence of fungi and fungal metabolites in moldy tomatoes. J Agric Food Chem 52: 7507-7513.
2. Antonello S, Rosalia F, Maria CS, Alejandro A, Alberto R (2009) Multitoxin extraction and detection of trichothecenes in cereals: an improved LC-MS/MS approach. J Sci Food Agric 89: 1145-1153.
3. Bayman P, Baker JL (2006) Ochratoxins: a global perspective. Mycopathologia 162: 215-223.
4. Birzele B, Prange A, Kramer J (2000) Deoxynivalenil and ochratoxin A in German wheat and changes of level in relation to storage parameters. Food Addit Contam 17(21): 1027-1035.
5. Dall'Asta C, Galaverna G, Aureli G, Dossena A, Marchelli R (2008) A LC/MS/MS method for the simultaneous quantification of free and masked fumonisins in maize-based products. World Mycotoxin J 1(3): 237-246.
6. EC Commission Regulation No. 1881/2006 (2006) Setting maximum levels for certain contaminants in foodstuffs.
7. EC, European Commission (2001) Reports on tasks for scientific co-operation. Collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by the population of EU Member States.
8. Ferrer I, García-Reyes JF, Mezcua M, Thurman EM, Fernández-Alba AR (2005) Multi-residue pesticide analysis in fruits and vegetables by liquid chromatography-time-of-flight mass spectrometry. J Chromatogr A 1082: 81-90.
9. Freire F, Kozakiewics Z, Paterson R (2000) Mycoflora and mycotoxins in Brazilian black pepper, white pepper and Brazi nuts. Mycopathologia 159: 281-289.
10. Hesseltine CW (1967) Aflatoxina and other mycotoxins. Health Lab Sci 4: 222-228.
11. Homdark S, Fehrmann F, Beck R (2000) Influence of different storage conditions on the mycotoxins production and quality of fusarium-infected wheat grain. J Phytopathol 148: 7-15.
12. Huang C-C (2010) Risk and control of mycotoxin. Food Ind Mon 42(4): 1-3.
13. Kokkonen Meri K, Jestoi Marika N (2009) A Multi-compound LC-MS/MS method for the screening of mycotoxins in grains. Food Anal Methods 2: 128-140.
14. Larsen TO, Gareis M, Frisvad JC (2002) Cell cytotoxicity and mycotoxin and secondary metabolite production by common Penicillia on cheese agar. J Agric Food Chem 50: 6148-6152.
15. Lattanzio VMT, Solfrizzo M, Powers S, Visconti A (2007) Simultaneous determination of aflatoxins, ochratoxin A and Fusarium toxins in maize by liquid chromatography/tandem mass spectrometry after multitoxin immunoaffinity cleanup. Rapid Commun Mass Spectrom 21: 3253-3261.
16. Lattanzio VMT, Gatta SD, Godula M, Visconti A (2011) Quantitative analysis of mycotoxins in cereal foods by collision cell fragmentation-high-resolution mass spectrometry: performance and comparison with triple-stage quadrupole detection. Food Addit Contam 28: 1424-1437.
17. Leong SL, Hocking AD, Pitt JI, Kazi BA, Emmett RW, Scott ES (2006) Australian research on ochratoxigenic fungi and ochratoxin A. Int J Food Microbiol 111: S10-S17.
18. Maurice OM (2002) Risk assessment for aflatoxins in foodstuffs. Int Biodeter Biodegr 50: 137-142.
19. Method of Test for Mycotoxin in Foods, www. fda. gov. tw/Bgradation_index. aspx? site_content_sn=42.
20. Michel S, Krska R, Rainer S (2010) Application of an LC-MS/MS based multi-mycotoxin method for the semi-quantitative determination of mycotoxins occurring in different types of food infected by moulds. Food Chem 119: 408-416.
21. Miller JD (1997) In: Trenholm HL (ed) Mycotoxin in grain. Compounds other than aflatoxins, 2nd edn. Eagan Press, St Paul, MN.
22. Nakagawa H, Ohmichi K, Sakamoto S, Sago Y, Kushiro M, Nagashima H, Yoshida M, Nakajima T (2011) Detection of a new Fusarium masked mycotoxin in wheat grains by high-resolution LC-Orbitrap™ MS. Food Addit Contam 28: 1447-1456.
23. Pena A, Seifrtova M, Lino C, Silveira I, Solich P (2006) Estimation of ochratoxin A in Portuguese population: new data on the occurrence in human urine by high performance liquid chromatography with fluorescence detection. Food Chem Toxicol 44: 1449-1454.
24. Ren Y, Zhang Y, Shao S, Cai Z, Feng L, Pan H, Wang Z (2007) Simultaneous determination of multi-component mycotoxin contaminants in food and feed by ultra-performance liquid chromatography tandem mass spectrometry. J Chromatogr A 1143: 48-64.
25. Spanjer MC, Rensen PM, Scholten JM (2008) LC-MS/MS multi-method for mycotoxin after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs. Food Addit Contam 25(4): 472-489.
26. Stecher G, Jarukamjorn K, Zaborski P, Bakry R, Huck CW, Bonn GK (2007) Evalution of extraction methods for the simultaneous analysis of simple and macrocyclic trichothecenes. Talanta 73: 251-257.
27. T-2 and HT-2 Toxins, www. inchem. org/documents/jecfa/jecmono/v47je06. htm.
28. van Pamel E, Vlaemynck G, Heyndrickx M, Herman L, Verbeken A, Daeseleire E (2011) Mycotoxin production by pure fungal isolates analysed by means of an UHPLC-MS/MS multi-mycotoxin method with possible pitfalls and solutions for patulin-producing isolates. Mycotoxicol Res 27: 37-47.
29. Waters Co. (2006) ACQUITY UPLC system quick start guide. Revision C. Waters Corporation, Massachusetts, USA.
30. Zinedine A, Soriano JM, Molto JC, Manes J (2007) Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogen mycotoxin. Food Chem Toxicol 45: 1-18.