C16 peptide shown to prevent leukocyte infiltration and alleviate detrimental inflammation in acute allergic encephalomyelitis model

Neuropharmacology

Volumn 70, Issue , 2013, Pages 83-99

  Fang, Marong ^a   Sun, Yayi ^a   Hu, Zhiying ^b   Yang, Jing ^a   Davies, Henry ^a   Wang, Beibei ^a   Ling, Shucai ^a   Han, Shu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b Hangzhou Red Cross Hospital   (China)

Author keywords

Anti inflammatory; C16; Experimental allergic encephalomyelitis; Multiple sclerosis; Neuroprotective effect

Indexed keywords

C16 PEPTIDE; MYELIN; NEUROPROTECTIVE AGENT; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTOSIS; BIOASSAY; BRAIN; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ELECTRON MICROSCOPY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE INFILTRATION; LYMPHOBLAST; MACROPHAGE MIGRATION INHIBITION; MALE; MIGRATION INHIBITION; MULTIPLE SCLEROSIS; NERVE CELL NECROSIS; NERVE FIBER; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TRANSENDOTHELIAL ASSAY; TREATMENT DURATION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CELL MOVEMENT; CENTRAL NERVOUS SYSTEM; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; INTEGRIN ALPHAVBETA3; LAMININ; LEUKOCYTES; LYMPHOCYTES; MACROPHAGES; MALE; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RATS;

EID: 84876954058     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.01.010     Document Type: Article

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