Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme

Journal of Biological Chemistry

Volumn 286, Issue 50, 2011, Pages 42808-42817

  Lamour, Nadia F ^a   Wijesinghe, Dayanjan S ^a,b   Mietla, Jennifer A ^a   Ward, Katherine E ^d   Stahelin, Robert V ^c,d   Chalfant, Charles E ^a,b,e  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NOTRE DAME   (United States)

^e VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACTS; CERAMIDE 1-PHOSPHATE; CERAMIDES; CONVERTING ENZYME; CYTOKINES; HIGH AFFINITY; IN-VITRO ANALYSIS; KNOCK OUTS; MURINE EMBRYONIC FIBROBLASTS; NEGATIVE REGULATORS; POTENT INHIBITOR; PROTEIN SEQUENCES; SPHINGOSINE 1 PHOSPHATES; TUMOR NECROSIS FACTORS; WILD TYPES;

AMIDES; BINDING SITES; CELL CULTURE; GLYCOPROTEINS; MACROPHAGES; MAMMALS; PHYSIOLOGY; TUMORS;

ENZYMES;

CERAMIDE 1 PHOSPHATE; CERAMIDE KINASE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EMBRYO; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; FIBROBLAST; GENETIC TRANSCRIPTION; IN VITRO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; WILD TYPE;

ADAM PROTEINS; ANIMALS; CELLS, CULTURED; CERAMIDES; FEMALE; MICE; MICE, KNOCKOUT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 83355166948     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.310169     Document Type: Article

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