Role of Arg403 for thermostability and catalytic activity of rabbit 12/15-lipoxygenase

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1831, Issue 6, 2013, Pages 1079-1088

  Di Venere, Almerinda ^a,b   Horn, Thomas ^c   Stehling, Sabine ^c   Mei, Giampiero ^a,b   Masgrau, Laura ^d   González Lafont, Àngels ^d   Kühn, Hartmut ^c   Ivanov, Igor ^e  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS NEUROMED   (Italy)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

Author keywords

Fluorescence studies; Lipid peroxidation; Lipoxygenases; Molecular dynamics; Motional flexibility; Thermal stability

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; ARGININE; CARBOXYLIC ACID; LEUCINE;

ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; FLUOROMETRY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LOCALIZATION; STATIC ELECTRICITY; THERMOSTABILITY; WILD TYPE;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; ARGININE; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; RABBITS; SPECTROMETRY, FLUORESCENCE; STATIC ELECTRICITY; TEMPERATURE; THERMODYNAMICS;

ORYCTOLAGUS CUNICULUS;

EID: 84876917235     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.02.006     Document Type: Article

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