Menin epigenetically represses hedgehog signaling in MEN1 tumor syndrome

Cancer Research

Volumn 73, Issue 8, 2013, Pages 2650-2658

  Gurung, Buddha ^a   Feng, Zijie ^a,c   Iwamoto, Daniel V ^a   Thiel, Austin ^a   Jin, Guanghui ^c   Fan, Chen Min ^d   Ng, Jessica M Y ^b   Curran, Tom ^b   Hua, Xianxin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c XIAMEN UNIVERSITY   (China)

^d GEOPHYSICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HISTONE H4 ARGININE 3 METHYLTRANSFERASE; METHIONINE; METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; VISMODEGIB;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; ENZYME ACTIVITY; EPIGENETICS; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GPI ANCHORED CELL SURFACE GENE; HISTONE METHYLATION; INSULINOMA; MICROARRAY ANALYSIS; MOUSE; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; ONCOGENE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANILIDES; ANIMALS; CELL CYCLE PROTEINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GPI-LINKED PROTEINS; HEDGEHOG PROTEINS; HISTONES; HUMANS; ISLETS OF LANGERHANS; METHYLATION; MICE; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN-ARGININE N-METHYLTRANSFERASES; PROTO-ONCOGENE PROTEINS; PYRIDINES; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84876902432     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3158     Document Type: Article

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