Inefficient antimicrobial functions of innate phagocytes render infant mice more susceptible to bacterial infection

European Journal of Immunology

Volumn 43, Issue 5, 2013, Pages 1322-1332

  Zhang, Qi ^a   Coveney, Andrew P ^b   Yu, Shenglin ^a   Liu, Jing Hua ^b   Li, Yiping ^a   Blankson, Siobhan ^b   Redmond, H Paul ^b   Wang, Jiang Huai ^b   Wang, Jian ^a  

^a CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b Department of Medicine National University of Ireland Cork   (Ireland)

Author keywords

Antimicrobial functions; Infant innate immunity; Phagocytes

Indexed keywords

CHEMOKINE RECEPTOR CXCR2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL IMMUNITY; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; CELL MATURATION; CONTROLLED STUDY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; IN VIVO STUDY; INFECTION RISK; INNATE IMMUNITY; LEUKOCYTE MIGRATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTE; PHAGOSOME; PRIORITY JOURNAL; SEPSIS;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CHEMOKINE CXCL2; CHEMOTAXIS; DISEASE SUSCEPTIBILITY; GENE EXPRESSION; IMMUNITY, INNATE; INJECTIONS, INTRAPERITONEAL; MACROPHAGES; MICE; MICE, INBRED C57BL; NEUTROPHILS; PHAGOSOMES; RECEPTORS, INTERLEUKIN-8B; SALMONELLA TYPHIMURIUM; SEPSIS; STAPHYLOCOCCUS AUREUS;

EID: 84876843489     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201243077     Document Type: Article

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