Retraction: AKAP13 Rho-GEF and PKD-Binding Domain Deficient Mice Develop Normally but Have an Abnormal Response to ?-Adrenergic-Induced Cardiac Hypertrophy (PLoS ONE (2013) 8: 4 (e627050 DOI: 10.1371/journal.pone.0062705);AKAP13 Rho-GEF and PKD-Binding Domain Deficient Mice Develop Normally but Have an Abnormal Response to β-Adrenergic-Induced Cardiac Hypertrophy

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Spindler, Matthew J ^a,b   Burmeister, Brian T ^c   Huang, Yu ^a   Hsiao, Edward C ^d   Salomonis, Nathan ^e   Scott, Mark J ^a   Srivastava, Deepak ^a,b,d   Carnegie, Graeme K ^c   Conklin, Bruce R ^a,b,d  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN 13; PROTEIN KINASE D; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN 13 GENE; ELECTROCARDIOGRAPHY; EMBRYO; GENE; HEART DEVELOPMENT; HEART EJECTION FRACTION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART SIZE; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; WILD TYPE;

MUS;

EID: 84876840288     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0296004     Document Type: Erratum

References (63)

1. Klingbeil P, Frazzetto G, Bouwmeester T, (2001) Xgravin-like (Xgl), a novel putative a-kinase anchoring protein (AKAP) expressed during embryonic development in Xenopus. Mech Dev 100: 323-326.
2. Weiser DC, Pyati UJ, Kimelman D, (2007) Gravin regulates mesodermal cell behavior changes required for axis elongation during zebrafish gastrulation. Genes Dev 21: 1559-1571.
3. Newhall KJ, Criniti AR, Cheah CS, Smith KC, Kafer KE, et al. (2006) Dynamic anchoring of PKA is essential during oocyte maturation. Curr Biol 16: 321-327.
4. Rawe VY, Payne C, Navara C, Schatten G, (2004) WAVE1 intranuclear trafficking is essential for genomic and cytoskeletal dynamics during fertilization: cell-cycle-dependent shuttling between M-phase and interphase nuclei. Dev Biol 276: 253-267.
5. Tunquist BJ, Hoshi N, Guire ES, Zhang F, Mullendorff K, et al. (2008) Loss of AKAP150 perturbs distinct neuronal processes in mice. Proc Natl Acad Sci U S A 105: 12557-12562.
6. Soderling SH, Guire ES, Kaech S, White J, Zhang F, et al. (2007) A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory. J Neurosci 27: 355-365.
7. Soderling SH, Langeberg LK, Soderling JA, Davee SM, Simerly R, et al. (2003) Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice. Proc Natl Acad Sci U S A 100: 1723-1728.
8. Tingley WG, Pawlikowska L, Zaroff JG, Kim T, Nguyen T, et al. (2007) Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation. Proc Natl Acad Sci U S A 104: 8461-8466.
9. Pare GC, Bauman AL, McHenry M, Michel JJ, Dodge-Kafka KL, et al. (2005) The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling. J Cell Sci 118: 5637-5646.
10. Chen L, Marquardt ML, Tester DJ, Sampson KJ, Ackerman MJ, et al. (2007) Mutation of an A-kinase-anchoring protein causes long-QT syndrome. Proc Natl Acad Sci U S A 104: 20990-20995.
11. Mayers CM, Wadell J, McLean K, Venere M, Malik M, et al. (2010) The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice. J Biol Chem 285: 12344-12354.
12. Carnegie GK, Means CK, Scott JD, (2009) A-kinase anchoring proteins: from protein complexes to physiology and disease. IUBMB Life 61: 394-406.
13. Wong W, Scott JD, (2004) AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Biol 5: 959-970.
14. Carnegie GK, Soughayer J, Smith FD, Pedroja BS, Zhang F, et al. (2008) AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Mol Cell 32: 169-179.
15. Diviani D, Baisamy L, Appert-Collin A, (2006) AKAP-Lbc: a molecular scaffold for the integration of cyclic AMP and Rho transduction pathways. Eur J Cell Biol 85: 603-610.
16. Kamp TJ, Hell JW, (2000) Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res. 87: 1095-1102.
17. McConnell BK, Popovic Z, Mal N, Lee K, Bautista J, et al. (2009) Disruption of protein kinase A interaction with A-kinase-anchoring proteins in the heart in vivo: effects on cardiac contractility, protein kinase A phosphorylation, and troponin I proteolysis. J Biol Chem 284: 1583-1592.
18. Mauban JR, O'Donnell M, Warrier S, Manni S, Bond M, (2009) AKAP-scaffolding proteins and regulation of cardiac physiology. Physiology (Bethesda) 24: 78-87.
19. Dodge-Kafka KL, Soughayer J, Pare GC, Carlisle Michel JJ, Langeberg LK, et al. (2005) The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature 437: 574-578.
20. Appert-Collin A, Cotecchia S, Nenniger-Tosato M, Pedrazzini T, Diviani D, (2007) The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A 104: 10140-10145.
21. Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, et al. (2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A 101: 6062-6067.
22. Hailesellasse Sene K, Porter CJ, Palidwor G, Perez-Iratxeta C, Muro EM, et al. (2007) Gene function in early mouse embryonic stem cell differentiation. BMC Genomics 8: 85.
23. Diviani D, Soderling J, Scott JD, (2001) AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation. J Biol Chem 276: 44247-44257.
24. Rubino D, Driggers P, Arbit D, Kemp L, Miller B, et al. (1998) Characterization of Brx, a novel Dbl family member that modulates estrogen receptor action. Oncogene 16: 2513-2526.
25. Toksoz D, Williams DA, (1994) Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products. Oncogene 9: 621-628.
26. Carnegie GK, Smith FD, McConnachie G, Langeberg LK, Scott JD, (2004) AKAP-Lbc nucleates a protein kinase D activation scaffold. Mol Cell 15: 889-899.
27. Klussmann E, Edemir B, Pepperle B, Tamma G, Henn V, et al. (2001) Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling. FEBS Lett 507: 264-268.
28. Vega RB, Harrison BC, Meadows E, Roberts CR, Papst PJ, et al. (2004) Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol 24: 8374-8385.
29. Gu JL, Muller S, Mancino V, Offermanns S, Simon MI, (2002) Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways. Proc Natl Acad Sci U S A 99: 9352-9357.
30. Offermanns S, Zhao LP, Gohla A, Sarosi I, Simon MI, et al. (1998) Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice. Embo J 17: 4304-4312.
31. Fielitz J, Kim MS, Shelton JM, Qi X, Hill JA, et al. (2008) Requirement of protein kinase D1 for pathological cardiac remodeling. Proc Natl Acad Sci U S A 105: 3059-3063.
32. Lin Q, Schwarz J, Bucana C, Olson EN, (1997) Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 276: 1404-1407.
33. Skarnes WC, (2000) Gene trapping methods for the identification and functional analysis of cell surface proteins in mice. Methods Enzymol 328: 592-615.
34. Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, et al. (2006) The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res 34: D642-648.
35. Fujita PA, Rhead B, Zweig AS, Hinrichs AS, Karolchik D, et al. (2010) The UCSC Genome Browser database: update 2011. Nucleic Acids Res [Epub ahead of print].
36. Burmeister BT, Taglieri DM, Wang L, Carnegie GK, (2012) Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heart. J Biol Chem 287: 40535-40546.
37. Edwards HV, Scott JD, Baillie GS, (2012) The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16). Biochem J 446: 437-443.
38. Jaehnig EJ, Heidt AB, Greene SB, Cornelissen I, Black BL, (2006) Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein. Mol Cell Biol 26: 9315-9326.
39. Zou Y, Komuro I, Yamazaki T, Kudoh S, Uozumi H, et al. (1999) Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy. J Biol Chem 274: 9760-9770.
40. Diviani D, Abuin L, Cotecchia S, Pansier L, (2004) Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex. Embo J 23: 2811-2820.
41. Amieux PS, Howe DG, Knickerbocker H, Lee DC, Su T, et al. (2002) Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo. J Biol Chem 277: 27294-27304.
42. Yin Z, Jones GN, Towns WH, 2nd, Zhang X, Abel ED, et al (2008) Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation 117: 1414-1422.
43. McCartney S, Little BM, Langeberg LK, Scott JD, (1995) Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. J Biol Chem 270: 9327-9333.
44. Kapiloff MS, Jackson N, Airhart N, (2001) mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope. J Cell Sci 114: 3167-3176.
45. Kapiloff MS, Schillace RV, Westphal AM, Scott JD, (1999) mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes. J Cell Sci 112 (Pt 16): 2725-2736.
46. Gelman IH, Tombler E, Vargas J Jr, (2000) A role for SSeCKS, a major protein kinase C substrate with tumour suppressor activity, in cytoskeletal architecture, formation of migratory processes, and cell migration during embryogenesis. Histochem J 32: 13-26.
47. Su B, Bu Y, Engelberg D, Gelman IH, (2010) SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway. J Biol Chem 285: 4578-4586.
48. Raeker MO, Bieniek AN, Ryan AS, Tsai HJ, Zahn KM, et al. (2010) Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain development. Dev Biol 337: 432-443.
49. Porchia F, Papucci M, Gargini C, Asta A, De Marco G, et al. (2008) Endothelin-1 up-regulates p115RhoGEF in embryonic rat cardiomyocytes during the hypertrophic response. J Recept Signal Transduct Res 28: 265-283.
50. Engelhardt S, Hein L, Wiesmann F, Lohse MJ, (1999) Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc Natl Acad Sci U S A 96: 7059-7064.
51. Bristow MR, (2000) beta-adrenergic receptor blockade in chronic heart failure. Circulation 101: 558-569.
52. Shibolet O, Giallourakis C, Rosenberg I, Mueller T, Xavier RJ, et al. (2007) AKAP13, a RhoA GTPase-specific guanine exchange factor, is a novel regulator of TLR2 signaling. J Biol Chem 282: 35308-35317.
53. Vitart V, Bencic G, Hayward C, Skunca Herman J, Huffman J, et al. (2010) New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8. Hum Mol Genet 19: 4304-4311.
54. Azorsa DO, Robeson RH, Frost D, Meec hoovet B, Brautigam GR, et al. (2010) High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation. BMC Genomics 11: 25.
55. Kino T, Souvatzoglou E, Charmandari E, Ichijo T, Driggers P, et al. (2006) Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system. J Biol Chem 281: 9118-9126.
56. Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, et al. (2009) Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature. Am J Pathol 174: 1650-1662.
57. Wirtenberger M, Tchatchou S, Hemminki K, Klaes R, Schmutzler RK, et al. (2006) Association of genetic variants in the Rho guanine nucleotide exchange factor AKAP13 with familial breast cancer. Carcinogenesis 27: 593-598.
58. Hu JK, Wang L, Li Y, Yang K, Zhang P, et al. (2010) The mRNA and protein expression of A-kinase anchor proteins 13 in human colorectal cancer. Clin Exp Med 10: 41-49.
59. Rozen S, Skaletsky H, (2000) Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132: 365-386.
60. Hastie CJ, McLauchlan HJ, Cohen P, (2006) Assay of protein kinases using radiolabeled ATP: a protocol. Nat Protoc 1: 968-971.
61. Tanabe S, Kreutz B, Suzuki N, Kozasa T, (2004) Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins. Methods Enzymol 390: 285-294.
62. Nuyens D, Stengl M, Dugarmaa S, Rossenbacker T, Compernolle V, et al. (2001) Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nat Med 7: 1021-1027.
63. Zhang Y, Takagawa J, Sievers RE, Khan MF, Viswanathan MN, et al. (2007) Validation of the wall motion score and myocardial performance indexes as novel techniques to assess cardiac function in mice after myocardial infarction. Am J Physiol Heart Circ Physiol 292: H1187-1192.