Modulating autophagy improves cardiac function in a rat model of early-stage dilated cardiomyopathy

Cardiology (Switzerland)

Volumn 125, Issue 1, 2013, Pages 60-68

  Xie, Kun ^a   Jin, Bo ^a   Li, Yong ^a   Luo, Xinping ^a   Zhu, Jun ^a   Ma, Duan ^a,b   Shi, Haiming ^a,c  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

Autophagic vacuole; Dilated cardiomyopathy; Experimental autoimmune myocarditis; Lewis rat; mTOR; Rapamycin

Indexed keywords

MYOSIN; RAPAMYCIN; CARDIAC MYOSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BODY WEIGHT; CELL VACUOLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DRUG MEGADOSE; HEART EJECTION FRACTION; HEART FUNCTION; IMMUNIZATION; LOW DRUG DOSE; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION; AUTOPHAGOSOME; CELL FUNCTION; COMPARATIVE STUDY; HEART FAILURE; HEART MUSCLE CELL; HISTOPATHOLOGY; LEWIS RAT; M MODE ECHOCARDIOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; TRANSTHORACIC ECHOCARDIOGRAPHY; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; AUTOIMMUNE DISEASES; AUTOPHAGY; CARDIOMYOPATHY, DILATED; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; RATS; RATS, INBRED LEW; SIROLIMUS; STROKE VOLUME; TOR SERINE-THREONINE KINASES; WEIGHT LOSS;

EID: 84876809036     PISSN: 00086312     EISSN: 14219751     Source Type: Journal    
DOI: 10.1159/000348308     Document Type: Article

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