메뉴 건너뛰기




Volumn 5, Issue 3, 2013, Pages 209-218

Interferon-λs: Special immunomodulatory agents and potential therapeutic targets

Author keywords

Allergy; Asthma; Cancer; Immunomodulation; Interferon

Indexed keywords

B7 ANTIGEN; BETA INTERFERON; CHEMOKINE RECEPTOR CCR7; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INDUCIBLE T CELL COSTIMULATOR LIGAND; INTERFERON; INTERFERON LAMBDA; INTERFERON LAMBDA 3; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 28A; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 8; JANUS KINASE; L SELECTIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT PROTEIN; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; IMMUNOMODULATING AGENT; INTERFERON RECEPTOR; LAMBDA INTERFERON;

EID: 84876785606     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000345365     Document Type: Review
Times cited : (14)

References (99)
  • 3
    • 78649744210 scopus 로고    scopus 로고
    • Structural analysis of cytokines comprising the IL-10 family
    • Zdanov A: Structural analysis of cytokines comprising the IL-10 family. Cytokine Growth Factor Rev 2010; 21:325-330.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 325-330
    • Zdanov, A.1
  • 7
    • 68849124573 scopus 로고    scopus 로고
    • Interferon-lambdas: The modulators of antivirus, antitumor, and immune responses
    • Li M, Liu X, Zhou Y, Su SB: Interferon-lambdas: the modulators of antivirus, antitumor, and immune responses. J Leukoc Biol 2009; 86: 23-32.
    • (2009) J Leukoc Biol , vol.86 , pp. 23-32
    • Li, M.1    Liu, X.2    Zhou, Y.3    Su, S.B.4
  • 8
    • 42149152139 scopus 로고    scopus 로고
    • An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity
    • Ank N, Iversen MB, Bartholdy C, Staeheli P, Hartmann R, Jensen UB, et al: An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity. J Immunol 2008; 180: 2474-2485.
    • (2008) J Immunol , vol.180 , pp. 2474-2485
    • Ank, N.1    Iversen, M.B.2    Bartholdy, C.3    Staeheli, P.4    Hartmann, R.5    Jensen, U.B.6
  • 9
    • 77955884931 scopus 로고    scopus 로고
    • Interferonlambda in the immune response to hepatitis B virus and hepatitis C virus
    • Pagliaccetti NE, Robek MD: Interferonlambda in the immune response to hepatitis B virus and hepatitis C virus. J Interferon Cytokine Res 2010; 30:585-590.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 585-590
    • Pagliaccetti, N.E.1    Robek, M.D.2
  • 10
    • 80051550050 scopus 로고    scopus 로고
    • Interferon lambdas: The next cytokine storm
    • Kelly C, Klenerman P, Barnes E: Interferon lambdas: the next cytokine storm. Gut 2011; 60:1284-1293.
    • (2011) Gut , vol.60 , pp. 1284-1293
    • Kelly, C.1    Klenerman, P.2    Barnes, E.3
  • 12
    • 77955880854 scopus 로고    scopus 로고
    • Interferon-lambda: A new addition to an old family
    • Donnelly R P, Kotenko SV: Interferon-lambda: a new addition to an old family. J Interferon Cytokine Res 2010; 30:555-564.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 555-564
    • Donnelly, R.P.1    Kotenko, S.V.2
  • 13
    • 35748976569 scopus 로고    scopus 로고
    • IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes
    • Osterlund PI, Pietila TE, Veckman V, Kotenko SV, Julkunen I: IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes. J Immunol 2007; 179:3434-3442.
    • (2007) J Immunol , vol.179 , pp. 3434-3442
    • Osterlund, P.I.1    Pietila, T.E.2    Veckman, V.3    Kotenko, S.V.4    Julkunen, I.5
  • 14
    • 77955860021 scopus 로고    scopus 로고
    • IL-28A, IL-28B, and IL-29: Promising cytokines with type I interferon-like properties
    • Witte K, Witte E, Sabat R, Wolk K: IL-28A, IL-28B, and IL-29: promising cytokines with type I interferon-like properties. Cytokine Growth Factor Rev 2010; 21:237-251.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 237-251
    • Witte, K.1    Witte, E.2    Sabat, R.3    Wolk, K.4
  • 15
    • 82755186757 scopus 로고    scopus 로고
    • Regulation of IFN-lambda1 promoter activity (IFN-lambda1/IL-29) in human airway epithelial cel ls
    • Siegel R, Eskdale J, Gallagher G: Regulation of IFN-lambda1 promoter activity (IFN-lambda1/IL-29) in human airway epithelial cel ls. J Immunol 2011; 187: 5636-5644.
    • (2011) J Immunol , vol.187 , pp. 5636-5644
    • Siegel, R.1    Eskdale, J.2    Gallagher, G.3
  • 16
    • 1642370060 scopus 로고    scopus 로고
    • Viral infection and toll-like receptor agonists induce a differential expression of type I and λ interferons in humans plasmacytoid and monocyte-derived dendritic cells
    • DOI 10.1002/eji.200324610
    • Coccia EM, Severa M, Giacomini E, Monneron D, Remoli ME, Julkunen I, et al: Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells. Eur J Immunol 2004; 34: 796-805. (Pubitemid 39255927)
    • (2004) European Journal of Immunology , vol.34 , Issue.3 , pp. 796-805
    • Coccia, E.M.1    Severa, M.2    Giacomini, E.3    Monneron, D.4    Remoli, M.E.5    Julkunen, I.6    Cella, M.7    Lande, R.8    Uze, G.9
  • 17
    • 84866428295 scopus 로고    scopus 로고
    • Expression profiles of human interferon-alpha and interfer-on-lambda subtypes are ligand- and cell-dependent
    • Hillyer P, Mane VP, Schramm LM, Puig M, Verthelyi D, Chen A, et al: Expression profiles of human interferon-alpha and interfer-on-lambda subtypes are ligand- and cell-dependent. Immunol Cell Biol 2012; 90:774-783.
    • (2012) Immunol Cell Biol , vol.90 , pp. 774-783
    • Hillyer, P.1    Mane, V.P.2    Schramm, L.M.3    Puig, M.4    Verthelyi, D.5    Chen, A.6
  • 18
    • 78651095500 scopus 로고    scopus 로고
    • CD14+ cell-derived IL-29 modulates pro-inflammatory cytokine production in patients with allergic airway inflammation
    • He S, Li T, Chen H, Ma W, Yao Q, Yang H, et al: CD14+ cell-derived IL-29 modulates pro-inflammatory cytokine production in patients with allergic airway inflammation. Allergy 2011; 66:238-246.
    • (2011) Allergy , vol.66 , pp. 238-246
    • He, S.1    Li, T.2    Chen, H.3    Ma, W.4    Yao, Q.5    Yang, H.6
  • 19
    • 77956450530 scopus 로고    scopus 로고
    • Expression and release of IL-29 by mast cells and modulation of mast cell behavior by IL-29
    • He S, Zhang H, Chen H, Yang H, Huang T, Chen Y, et al: Expression and release of IL-29 by mast cells and modulation of mast cell behavior by IL-29. Allergy 2010; 65:1234-1241.
    • (2010) Allergy , vol.65 , pp. 1234-1241
    • He, S.1    Zhang, H.2    Chen, H.3    Yang, H.4    Huang, T.5    Chen, Y.6
  • 20
    • 63149173773 scopus 로고    scopus 로고
    • Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to inf luenza A infection
    • Wang J, Oberley-Deegan R, Wang S, Nikrad M, Funk CJ, Hartshorn KL, et al: Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to inf luenza A infection. J Immunol 2009; 182: 1296-1304.
    • (2009) J Immunol , vol.182 , pp. 1296-1304
    • Wang, J.1    Oberley-Deegan, R.2    Wang, S.3    Nikrad, M.4    Funk, C.J.5    Hartshorn, K.L.6
  • 21
    • 2342444617 scopus 로고    scopus 로고
    • Full house: 12 Receptors for 27 cytokines
    • DOI 10.1016/j.intimp.2004.01.003, PII S1567576904000062
    • Kotenko SV, Langer JA: Full house: 12 receptors for 27 cytokines. Int Immunopharmacol 2004; 4: 593-608. (Pubitemid 38559077)
    • (2004) International Immunopharmacology , vol.4 , Issue.5 , pp. 593-608
    • Kotenko, S.V.1    Langer, J.A.2
  • 22
    • 3442888513 scopus 로고    scopus 로고
    • The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain
    • DOI 10.1189/jlb.0204117
    • Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H: The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R 2) chain. J Leukoc Biol 2004; 76: 314 - 321. (Pubitemid 39006944)
    • (2004) Journal of Leukocyte Biology , vol.76 , Issue.2 , pp. 314-321
    • Donnelly, R.P.1    Sheikh, F.2    Kotenko, S.V.3    Dickensheets, H.4
  • 23
    • 73849130903 scopus 로고    scopus 로고
    • Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: Implications for therapeutic applications of these cytokines
    • Witte K, Gruetz G, Volk HD, Looman AC, Asadullah K, Sterry W, et al: Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Genes Immun 2009; 10:702-714.
    • (2009) Genes Immun , vol.10 , pp. 702-714
    • Witte, K.1    Gruetz, G.2    Volk, H.D.3    Looman, A.C.4    Asadullah, K.5    Sterry, W.6
  • 24
    • 34447273319 scopus 로고    scopus 로고
    • Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases
    • DOI 10.1128/JVI.02438-06
    • Zhou Z, Hamming OJ, Ank N, Paludan SR, Nielsen AL, Hartmann R: Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases. J Virol 2007; 81: 7749-7758. (Pubitemid 47047861)
    • (2007) Journal of Virology , vol.81 , Issue.14 , pp. 7749-7758
    • Zhou, Z.1    Hamming, O.J.2    Ank, N.3    Paludan, S.R.4    Nielsen, A.L.5    Hartmann, R.6
  • 26
    • 3242672021 scopus 로고    scopus 로고
    • Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-λ1. Similarities with type 1 interferon signaling
    • DOI 10.1074/jbc.M404789200
    • Dumoutier L, Tounsi A, Michiels T, Sommereyns C, Kotenko SV, Renauld JC: Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling. J Biol Chem 2004; 279: 32269-32274. (Pubitemid 39014676)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.31 , pp. 32269-32274
    • Dumoutier, L.1    Tounsi, A.2    Michiels, T.3    Sommereyns, C.4    Kotenko, S.V.5    Renauld, J.-C.6
  • 29
    • 42949160129 scopus 로고    scopus 로고
    • I F N-La mbda (I F N-La mbda) is expres sed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo
    • Sommereyns C, Paul S, Staeheli P, Michiels T: I F N-la mbda (I F N-la mbda) is expres sed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo. PLoS Pathog 2008; 4:e1000017.
    • (2008) PLoS Pathog , vol.4
    • Sommereyns, C.1    Paul, S.2    Staeheli, P.3    Michiels, T.4
  • 31
    • 77951983557 scopus 로고    scopus 로고
    • Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections
    • Mordstein M, Neugebauer E, Ditt V, Jessen B, Rieger T, Falcone V, et al: Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections. J Virol 2010; 84: 5670-5677.
    • (2010) J Virol , vol.84 , pp. 5670-5677
    • Mordstein, M.1    Neugebauer, E.2    Ditt, V.3    Jessen, B.4    Rieger, T.5    Falcone, V.6
  • 32
    • 77956643985 scopus 로고    scopus 로고
    • Temporal and spatial resolution of type I and III interferon responses in vivo
    • Pulverer JE, Rand U, Lienenklaus S, Kugel D, Zietara N, Kochs G, et al: Temporal and spatial resolution of type I and III interferon responses in vivo. J Virol 2010; 84:8626-8638.
    • (2010) J Virol , vol.84 , pp. 8626-8638
    • Pulverer, J.E.1    Rand, U.2    Lienenklaus, S.3    Kugel, D.4    Zietara, N.5    Kochs, G.6
  • 34
    • 61849126356 scopus 로고    scopus 로고
    • Human interferonlambda3 is a potent member of the type III interferon family
    • Dellgren C, Gad HH, Hamming OJ, Melchjorsen J, Hartmann R: Human interferonlambda3 is a potent member of the type III interferon family. Genes Immun 2009; 10: 125-131.
    • (2009) Genes Immun , vol.10 , pp. 125-131
    • Dellgren, C.1    Gad, H.H.2    Hamming, O.J.3    Melchjorsen, J.4    Hartmann, R.5
  • 35
    • 79952130188 scopus 로고    scopus 로고
    • IL-29 and IFNalpha differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNgamma receptor expression
    • Liu BS, Janssen HL, Boonstra A: IL-29 and IFNalpha differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNgamma receptor expression. Blood 2011; 117:2385-2395.
    • (2011) Blood , vol.117 , pp. 2385-2395
    • Liu, B.S.1    Janssen, H.L.2    Boonstra, A.3
  • 36
    • 78650149393 scopus 로고    scopus 로고
    • Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus
    • Diegelmann J, Beigel F, Zitzmann K, Kaul A, Goke B, Auernhammer CJ, et al: Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. PLoS One 2010; 5:e15200.
    • (2010) PLoS One , vol.5
    • Diegelmann, J.1    Beigel, F.2    Zitzmann, K.3    Kaul, A.4    Goke, B.5    Auernhammer, C.J.6
  • 37
    • 84869450003 scopus 로고    scopus 로고
    • Combined action of type I and type III interferon restricts initial replication of SARS-coronavirus in the lung but fails to inhibit systemic virus spread
    • E-pub ahead of print
    • Mahlakoiv T, Ritz D, Mordstein M, Dediego ML, Enjuanes L, Muller MA, et al: Combined action of type I and type III interferon restricts initial replication of SARS-Coronavirus in the lung but fails to inhibit systemic virus spread. J Gen Virol 2012, E-pub ahead of print.
    • (2012) J Gen Virol
    • Mahlakoiv, T.1    Ritz, D.2    Mordstein, M.3    Dediego, M.L.4    Enjuanes, L.5    Muller, M.A.6
  • 41
    • 77952730427 scopus 로고    scopus 로고
    • Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection
    • Li JH, Lao XQ, Tillmann HL, Rowell J, Patel K, Thompson A, et al: Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection. Hepatology 2010; 51: 1904-1911.
    • (2010) Hepatology , vol.51 , pp. 1904-1911
    • Li, J.H.1    Lao, X.Q.2    Tillmann, H.L.3    Rowell, J.4    Patel, K.5    Thompson, A.6
  • 42
    • 78649608515 scopus 로고    scopus 로고
    • IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C
    • Urban TJ, Thompson AJ, Bradrick SS, Fellay J, Schuppan D, Cronin KD, et al: IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C. Hepatology 2010; 52:1888-1896.
    • (2010) Hepatology , vol.52 , pp. 1888-1896
    • Urban, T.J.1    Thompson, A.J.2    Bradrick, S.S.3    Fellay, J.4    Schuppan, D.5    Cronin, K.D.6
  • 43
    • 78049265857 scopus 로고    scopus 로고
    • Host genetic basis for hepatitis C virus clearance: A role for blood collection centers
    • Selvarajah S, Tobler LH, Simmons G, Busch MP: Host genetic basis for hepatitis C virus clearance: a role for blood collection centers. Curr Opin Hematol 2010; 17:550-557.
    • (2010) Curr Opin Hematol , vol.17 , pp. 550-557
    • Selvarajah, S.1    Tobler, L.H.2    Simmons, G.3    Busch, M.P.4
  • 44
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, Simon JS, Shianna K V, Urban TJ, et al: Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009; 461: 399 - 401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3    Simon, J.S.4    Shianna, K.V.5    Urban, T.J.6
  • 45
    • 77949831342 scopus 로고    scopus 로고
    • Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: A genome-wide association study
    • 1345.e1-e7
    • Rauch A, Kutalik Z, Descombes P, Cai T, Di Iulio J, Mueller T, et al: Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology 2010; 138: 1338-1345, 1345.e1-e7.
    • (2010) Gastroenterology , vol.138 , pp. 1338-1345
    • Rauch, A.1    Kutalik, Z.2    Descombes, P.3    Cai, T.4    Di Iulio, J.5    Mueller, T.6
  • 48
  • 49
    • 47949127385 scopus 로고    scopus 로고
    • IF-nalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity
    • Maher SG, Sheikh F, Scarzello AJ, Romero-Weaver AL, Baker DP, Donnelly RP, et al: IF-Nalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity. Cancer Biol Ther 2008; 7:1109-1115.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1109-1115
    • Maher, S.G.1    Sheikh, F.2    Scarzello, A.J.3    Romero-Weaver, A.L.4    Baker, D.P.5    Donnelly, R.P.6
  • 50
    • 80055019697 scopus 로고    scopus 로고
    • Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferonlambda genes produced anti-tumour effects
    • Li Q, Kawamura K, Okamoto S, Fujie H, Numasaki M, Namba M, et al: Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferonlambda genes produced anti-tumour effects. Br J Cancer 2011; 105: 1302-1312.
    • (2011) Br J Cancer , vol.105 , pp. 1302-1312
    • Li, Q.1    Kawamura, K.2    Okamoto, S.3    Fujie, H.4    Numasaki, M.5    Namba, M.6
  • 51
    • 71049171694 scopus 로고    scopus 로고
    • Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anticancer agents
    • Li Q, Kawamura K, Ma G, Iwata F, Numasaki M, Suzuki N, et al: Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anticancer agents. Eur J Cancer 2010; 46: 180 - 190.
    • (2010) Eur J Cancer , vol.46 , pp. 180-190
    • Li, Q.1    Kawamura, K.2    Ma, G.3    Iwata, F.4    Numasaki, M.5    Suzuki, N.6
  • 52
    • 33646185492 scopus 로고    scopus 로고
    • Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo
    • Ank N, West H, Bartholdy C, Eriksson K, Thomsen AR, Paludan SR: Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo. J Virol 2006; 80: 4501-4509.
    • (2006) J Virol , vol.80 , pp. 4501-4509
    • Ank, N.1    West, H.2    Bartholdy, C.3    Eriksson, K.4    Thomsen, A.R.5    Paludan, S.R.6
  • 53
    • 77953623141 scopus 로고    scopus 로고
    • IL-4 enhances IFN-lambda1 (IL-29) production by plasmacytoid DCs via monocyte secretion of IL-1Ra
    • Megjugorac NJ, Gallagher GE, Gallagher G: IL-4 enhances IFN-lambda1 (IL-29) production by plasmacytoid DCs via monocyte secretion of IL-1Ra. Blood 2010; 115: 4185-4190.
    • (2010) Blood , vol.115 , pp. 4185-4190
    • Megjugorac, N.J.1    Gallagher, G.E.2    Gallagher, G.3
  • 55
    • 78649417586 scopus 로고    scopus 로고
    • Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC
    • Lauterbach H, Bathke B, Gilles S, Traidl-Hoffmann C, Luber CA, Fejer G, et al: Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC. J Exp Med 2010; 207: 2703-2717.
    • (2010) J Exp Med , vol.207 , pp. 2703-2717
    • Lauterbach, H.1    Bathke, B.2    Gilles, S.3    Traidl-Hoffmann, C.4    Luber, C.A.5    Fejer, G.6
  • 56
    • 77950822768 scopus 로고    scopus 로고
    • Ex pression of type III interferon (IF N) in the vaginal mucosa is mediated primarily by dendritic cells and displays stronger dependence on NF-kappaB than type I IFNs
    • Iversen MB, Ank N, Melchjorsen J, Paludan SR: Expression of type III interferon (IF N) in the vaginal mucosa is mediated primarily by dendritic cells and displays stronger dependence on NF-kappaB than type I IFNs. J Virol 2010; 84: 4579-4586.
    • (2010) J Virol , vol.84 , pp. 4579-4586
    • Iversen, M.B.1    Ank, N.2    Melchjorsen, J.3    Paludan, S.R.4
  • 57
    • 84862019026 scopus 로고    scopus 로고
    • HHV-6B induces IFN-lambda1 responses in cord plasmacytoid dendritic cells through TLR9
    • Nordstrom I, Eriksson K: HHV-6B induces IFN-lambda1 responses in cord plasmacytoid dendritic cells through TLR9. PLoS One 2012; 7:e38683.
    • (2012) PLoS One , vol.7
    • Nordstrom, I.1    Eriksson, K.2
  • 58
    • 73149093219 scopus 로고    scopus 로고
    • Modulation of human plasmacytoid DC function by IFN-lambda1 (IL-29)
    • Megjugorac NJ, Gallagher GE, Gallagher G: Modulation of human plasmacytoid DC function by IFN-lambda1 (IL-29). J Leukoc Biol 2009; 86:1359-1363.
    • (2009) J Leukoc Biol , vol.86 , pp. 1359-1363
    • Megjugorac, N.J.1    Gallagher, G.E.2    Gallagher, G.3
  • 59
    • 84866163478 scopus 로고    scopus 로고
    • Type III IFNs are produced by and stimulate human plasmacytoid dendritic cel ls
    • Yin Z, Dai J, Deng J, Sheikh F, Natalia M, Shih T, et al: Type III IFNs are produced by and stimulate human plasmacytoid dendritic cel ls. J Immunol 2012; 189: 2735-2745.
    • (2012) J Immunol , vol.189 , pp. 2735-2745
    • Yin, Z.1    Dai, J.2    Deng, J.3    Sheikh, F.4    Natalia, M.5    Shih, T.6
  • 61
    • 79957896032 scopus 로고    scopus 로고
    • IL-28A (IFN-lambda2) modulates lung DC function to promote th1 immune skewing and suppress allergic airway disease
    • Koltsida O, Hausding M, Stavropoulos A, Koch S, Tzelepis G, Ubel C, et al: IL-28A (IFN-lambda2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease. EMBO Mol Med 2011; 3:348-361.
    • (2011) EMBO Mol Med , vol.3 , pp. 348-361
    • Koltsida, O.1    Hausding, M.2    Stavropoulos, A.3    Koch, S.4    Tzelepis, G.5    Ubel, C.6
  • 62
    • 33744492302 scopus 로고    scopus 로고
    • Interferon-λ-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells
    • DOI 10.1182/blood-2005-10-4129
    • Mennechet FJ, Uze G: Interferon-lambdatreated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells. Blood 2006; 107:4417-4423. (Pubitemid 43801368)
    • (2006) Blood , vol.107 , Issue.11 , pp. 4417-4423
    • Mennechet, F.J.D.1    Uze, G.2
  • 63
    • 67651121930 scopus 로고    scopus 로고
    • IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses th2 responses in human naive and memory T cells
    • Dai J, Megjugorac NJ, Gallagher GE, Yu RY, Gallagher G: IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells. Blood 2009; 113: 5829-5838.
    • (2009) Blood , vol.113 , pp. 5829-5838
    • Dai, J.1    Megjugorac, N.J.2    Gallagher, G.E.3    Yu, R.Y.4    Gallagher, G.5
  • 64
    • 55449093555 scopus 로고    scopus 로고
    • Interferonlambda1 (interleukin-29) preferentially down-regulates interleukin-13 over other T helper type 2 cytokine responses in vitro
    • Srinivas S, Dai J, Eskdale J, Gallagher GE, Megjugorac NJ, Gallagher G: Interferonlambda1 (interleukin-29) preferentially down-regulates interleukin-13 over other T helper type 2 cytokine responses in vitro. Immunology 2008; 125:492-502.
    • (2008) Immunology , vol.125 , pp. 492-502
    • Srinivas, S.1    Dai, J.2    Eskdale, J.3    Gallagher, G.E.4    Megjugorac, N.J.5    Gallagher, G.6
  • 65
    • 77956266397 scopus 로고    scopus 로고
    • IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques
    • Morrow MP, Yan J, Pankhong P, Shedlock DJ, Lewis MG, Talbott K, et al: IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques. Mol Ther 2010; 18: 1714-1723.
    • (2010) Mol Ther , vol.18 , pp. 1714-1723
    • Morrow, M.P.1    Yan, J.2    Pankhong, P.3    Shedlock, D.J.4    Lewis, M.G.5    Talbott, K.6
  • 66
    • 67651115867 scopus 로고    scopus 로고
    • Comparative ability of IL-12 and IL-28B to regulate treg populations and enhance adaptive cellular immunity
    • Morrow MP, Pankhong P, Laddy DJ, Schoenly KA, Yan J, Cisper N, et al: Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity. Blood 2009; 113: 5868-5877.
    • (2009) Blood , vol.113 , pp. 5868-5877
    • Morrow, M.P.1    Pankhong, P.2    Laddy, D.J.3    Schoenly, K.A.4    Yan, J.5    Cisper, N.6
  • 70
    • 33847795900 scopus 로고    scopus 로고
    • - CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-γ-independent manner
    • DOI 10.1038/sj.gene.6364372, PII 6364372
    • Pekarek V, Srinivas S, Eskdale J, Gallagher G: Interferon lambda-1 (IFN-lambda1/IL-29) induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-gamma-independent manner. Genes Immun 2007; 8:177-180. (Pubitemid 46390918)
    • (2007) Genes and Immunity , vol.8 , Issue.2 , pp. 177-180
    • Pekarek, V.1    Srinivas, S.2    Eskdale, J.3    Gallagher, G.4
  • 71
    • 33846496110 scopus 로고    scopus 로고
    • Modulation of the human cytokine response by interferon lambda-1 (IFN-λ1/IL-29)
    • DOI 10.1038/sj.gene.6364348, PII 6364348
    • Jordan WJ, Eskdale J, Boniotto M, Rodia M, Kellner D, Gallagher G: Modulation of the human cytokine response by interferon lambda-1 (IFN-lambda1/IL-29). Genes Immun 2007; 8:13-20. (Pubitemid 46164287)
    • (2007) Genes and Immunity , vol.8 , Issue.1 , pp. 13-20
    • Jordan, W.J.1    Eskdale, J.2    Boniotto, M.3    Rodia, M.4    Kellner, D.5    Gallagher, G.6
  • 72
    • 84865772924 scopus 로고    scopus 로고
    • Type I and III interferons enhance IL-10 receptor expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12
    • Liu BS, Janssen HL, Boonstra A: Type I and III interferons enhance IL-10 receptor expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12. Eur J Immunol 2012; 42:2431-2440.
    • (2012) Eur J Immunol , vol.42 , pp. 2431-2440
    • Liu, B.S.1    Janssen, H.L.2    Boonstra, A.3
  • 73
    • 79959996480 scopus 로고    scopus 로고
    • Interferon-lambda mediates oral tolerance and inhibits antigen-specific, T-helper 2 cell-mediated inflammation in mouse intestine
    • 258.e1-e2
    • He SH, Chen X, Song CH, Liu ZQ, Zhou LF, Ma WJ, et al: Interferon-lambda mediates oral tolerance and inhibits antigen-specific, T-helper 2 cell-mediated inflammation in mouse intestine. Gastroenterology 2011; 141: 249-258, 258.e1-e2.
    • (2011) Gastroenterology , vol.141 , pp. 249-258
    • He, S.H.1    Chen, X.2    Song, C.H.3    Liu, Z.Q.4    Zhou, L.F.5    Ma, W.J.6
  • 75
    • 84868155894 scopus 로고    scopus 로고
    • IFN type I and type II independent enhancement of B cell TLR7 expression by natural killer cells
    • Sinha S, Guo Y, Thet S, Yuan D: IFN type I and type II independent enhancement of B cell TLR7 expression by natural killer cells. J Leukoc Biol 2012; 92: 713-722.
    • (2012) J Leukoc Biol , vol.92 , pp. 713-722
    • Sinha, S.1    Guo, Y.2    Thet, S.3    Yuan, D.4
  • 76
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ: Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011; 331: 1565-1570.
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 77
    • 80053133357 scopus 로고    scopus 로고
    • Antitumor activities of recombinant human interferon (IFN)-lambda1 in vitro and in xenograft models in vivo for colon cancer
    • Hui X, Chen H, Zhang S, Ma X, Wang X, Huang B: Antitumor activities of recombinant human interferon (IFN)-lambda1 in vitro and in xenograft models in vivo for colon cancer. Cancer Lett 2011; 311: 141-151.
    • (2011) Cancer Lett , vol.311 , pp. 141-151
    • Hui, X.1    Chen, H.2    Zhang, S.3    Ma, X.4    Wang, X.5    Huang, B.6
  • 78
    • 80054982461 scopus 로고    scopus 로고
    • Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small cell lung cancer
    • Fujie H, Tanaka T, Tagawa M, Kaijun N, Watanabe M, Suzuki T, et al: Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small cell lung cancer. Cancer Sci 2011; 102: 1977-1990.
    • (2011) Cancer Sci , vol.102 , pp. 1977-1990
    • Fujie, H.1    Tanaka, T.2    Tagawa, M.3    Kaijun, N.4    Watanabe, M.5    Suzuki, T.6
  • 79
    • 33646242995 scopus 로고    scopus 로고
    • Characterization of the mouse IFN-lambda ligandreceptor system: Ifn-lambdas exhibit antitumor activity against B16 melanoma
    • Lasfar A, Lewis-Antes A, Smirnov SV, Anantha S, Abushahba W, Tian B, et al: Characterization of the mouse IFN-lambda ligandreceptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma. Cancer Res 2006; 66:4468-4477.
    • (2006) Cancer Res , vol.66 , pp. 4468-4477
    • Lasfar, A.1    Lewis-Antes, A.2    Smirnov, S.V.3    Anantha, S.4    Abushahba, W.5    Tian, B.6
  • 80
    • 77953172635 scopus 로고    scopus 로고
    • Type III IFN interleukin-28 mediates the antitumor efficacy of oncolytic virus VSV in immune-competent mouse models of cancer
    • Wongthida P, Diaz RM, Galivo F, Kottke T, Thompson J, Pulido J, et al: Type III IFN interleukin-28 mediates the antitumor efficacy of oncolytic virus VSV in immune-competent mouse models of cancer. Cancer Res 2010; 70:4539-4549.
    • (2010) Cancer Res , vol.70 , pp. 4539-4549
    • Wongthida, P.1    Diaz, R.M.2    Galivo, F.3    Kottke, T.4    Thompson, J.5    Pulido, J.6
  • 82
    • 77955886364 scopus 로고    scopus 로고
    • Interferon-lambda as a potential therapeutic agent in cancer treatment
    • Steen HC, Gamero AM: Interferon-lambda as a potential therapeutic agent in cancer treatment. J Interferon Cytokine Res 2010; 30: 597-602.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 597-602
    • Steen, H.C.1    Gamero, A.M.2
  • 84
    • 84861668363 scopus 로고    scopus 로고
    • Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells
    • Vareille M, Kieninger E, Alves MP, Kopf BS, Moller A, Geiser T, et al: Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells. Thorax 2012; 67:517-525.
    • (2012) Thorax , vol.67 , pp. 517-525
    • Vareille, M.1    Kieninger, E.2    Alves, M.P.3    Kopf, B.S.4    Moller, A.5    Geiser, T.6
  • 86
    • 0038387445 scopus 로고    scopus 로고
    • To respond or not to respond: T cells in allergic asthma
    • DOI 10.1038/nri1084
    • Herrick CA, Bottomly K: To respond or not to respond: T cells in allergic asthma. Nat Rev Immunol 2003; 3: 405-412. (Pubitemid 37323200)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.5 , pp. 405-412
    • Herrick, C.A.1    Bottomly, K.2
  • 87
    • 79957892829 scopus 로고    scopus 로고
    • Interferon-lambda as a new approach for treatment of allergic asthma?
    • Edwards MR, Johnston SL: Interferon-lambda as a new approach for treatment of allergic asthma? EMBO Mol Med 2011; 3: 306-308.
    • (2011) EMBO Mol Med , vol.3 , pp. 306-308
    • Edwards, M.R.1    Johnston, S.L.2
  • 88
    • 60849114033 scopus 로고    scopus 로고
    • Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cel ls
    • Khaitov MR, Laza-Stanca V, Edwards MR, Walton RP, Rohde G, Contoli M, et al: Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cel ls. Allergy 2009; 64: 375-386.
    • (2009) Allergy , vol.64 , pp. 375-386
    • Khaitov, M.R.1    Laza-Stanca, V.2    Edwards, M.R.3    Walton, R.P.4    Rohde, G.5    Contoli, M.6
  • 92
    • 79959272970 scopus 로고    scopus 로고
    • Interferon-lambda1 induces peripheral blood mononuclear cell-derived chemokines secretion in patients with systemic lupus erythematosus: Its correlation with disease activity
    • Wu Q, Yang Q, Lourenco E, Sun H, Zhang Y: Interferon-lambda1 induces peripheral blood mononuclear cell-derived chemokines secretion in patients with systemic lupus erythematosus: its correlation with disease activity. Arthritis Res Ther 2011; 13: R88.
    • (2011) Arthritis Res Ther , vol.13
    • Wu, Q.1    Yang, Q.2    Lourenco, E.3    Sun, H.4    Zhang, Y.5
  • 93
    • 83155180585 scopus 로고    scopus 로고
    • Profiling the expression of interleukin (IL)-28 and IL-28 receptor alpha in systemic lupus erythematosus patients
    • Lin SC, Kuo CC, Tsao JT, Lin LJ: Profiling the expression of interleukin (IL)-28 and IL-28 receptor alpha in systemic lupus erythematosus patients. Eur J Clin Invest 2012; 42:61-69.
    • (2012) Eur J Clin Invest , vol.42 , pp. 61-69
    • Lin, S.C.1    Kuo, C.C.2    Tsao, J.T.3    Lin, L.J.4
  • 94
    • 78650261558 scopus 로고    scopus 로고
    • Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFN-lambda) in cutaneous lupus erythematosus
    • Zahn S, Rehkamper C, Kummerer BM, Ferring-Schmidt S, Bieber T, Tuting T, et al: Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFN-lambda) in cutaneous lupus erythematosus. J Invest Dermatol 2011; 131: 133-140.
    • (2011) J Invest Dermatol , vol.131 , pp. 133-140
    • Zahn, S.1    Rehkamper, C.2    Kummerer, B.M.3    Ferring-Schmidt, S.4    Bieber, T.5    Tuting, T.6
  • 95
    • 84862819877 scopus 로고    scopus 로고
    • Eosinophil-derived interfer-on-lambda contributes to initiation of allergen-related inflammation in the intestine
    • He SH, Song CH, Liu Z, Zhang H, Ma W, Zhou LF, et al: Eosinophil-derived interfer-on-lambda contributes to initiation of allergen-related inflammation in the intestine. Cy tok ine 2012; 58: 186-192.
    • (2012) Cy Tok Ine , vol.58 , pp. 186-192
    • He, S.H.1    Song, C.H.2    Liu, Z.3    Zhang, H.4    Ma, W.5    Zhou, L.F.6
  • 96
    • 33846197963 scopus 로고    scopus 로고
    • IL-28A Is a Key Regulator of T-Cell-Mediated Liver Injury via the T-Box Transcription Factor T-Bet
    • DOI 10.1053/j.gastro.2006.10.028, PII S0016508506022621
    • Siebler J, Wirtz S, Weigmann B, Atreya I, Schmitt E, Kreft A, et al: IL-28A is a key regulator of T-cell-mediated liver injury via the T-box transcription factor T-bet. Gastroenterology 2007; 132: 358-371. (Pubitemid 46108741)
    • (2007) Gastroenterology , vol.132 , Issue.1 , pp. 358-371
    • Siebler, J.1    Wirtz, S.2    Weigmann, B.3    Atreya, I.4    Schmitt, E.5    Kreft, A.6    Galle, P.R.7    Neurath, M.F.8
  • 97
    • 0036533489 scopus 로고    scopus 로고
    • Cytokines as a link between innate and adaptive antitumor immunity
    • DOI 10.1016/S1471-4906(02)02195-6, PII S1471490602021956
    • Belardelli F, Ferrantini M: Cytokines as a link between innate and adaptive antitumor immunity. Trends Immunol 2002; 23: 201-208. (Pubitemid 34260936)
    • (2002) Trends in Immunology , vol.23 , Issue.4 , pp. 201-208
    • Belardelli, F.1    Ferrantini, M.2
  • 98
    • 77951491478 scopus 로고    scopus 로고
    • Recent advances on the immunomodulatory effects of IFN-alpha: Implications for cancer immunotherapy and autoimmunity
    • Rizza P, Moretti F, Belardelli F: Recent advances on the immunomodulatory effects of IFN-alpha: implications for cancer immunotherapy and autoimmunity. Autoimmunity 2010; 43: 204-209.
    • (2010) Autoimmunity , vol.43 , pp. 204-209
    • Rizza, P.1    Moretti, F.2    Belardelli, F.3
  • 99
    • 79952172888 scopus 로고    scopus 로고
    • Interferon-lambda in HCV infection and therapy
    • Pagliaccetti NE, Robek MD: Interferon-lambda in HCV infection and therapy. Viruses 2010; 2:1589-1602.
    • (2010) Viruses , vol.2 , pp. 1589-1602
    • Pagliaccetti, N.E.1    Robek, M.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.