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Volumn 102, Issue 11, 2011, Pages 1977-1990

Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small cell lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYCLIN DEPENDENT KINASE INHIBITOR 1; INTERFERON RECEPTOR; INTERLEUKIN 28; INTERLEUKIN 29; KI 67 ANTIGEN; PROTEIN P21; SMALL INTERFERING RNA;

EID: 80054982461     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2011.02079.x     Document Type: Article
Times cited : (35)

References (48)
  • 1
    • 0037232131 scopus 로고    scopus 로고
    • Novel interferons
    • Vilcek J. Novel interferons. Nat Immunol 2003; 4: 8-9.
    • (2003) Nat Immunol , vol.4 , pp. 8-9
    • Vilcek, J.1
  • 2
    • 0037236826 scopus 로고    scopus 로고
    • IL-28, IL-29 and their class II cytokine receptor IL-28R
    • Sheppard P, Kindsvogel W, Xu W et al. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat Immunol 2003; 4: 63-8.
    • (2003) Nat Immunol , vol.4 , pp. 63-68
    • Sheppard, P.1    Kindsvogel, W.2    Xu, W.3
  • 3
    • 0037243222 scopus 로고    scopus 로고
    • IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
    • Kotenko SV, Gallagher G, Baurin VV et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol 2003; 4: 69-77.
    • (2003) Nat Immunol , vol.4 , pp. 69-77
    • Kotenko, S.V.1    Gallagher, G.2    Baurin, V.V.3
  • 4
    • 0032232899 scopus 로고    scopus 로고
    • Mechanism of interferon action
    • Leaman DW. Mechanism of interferon action. Prog Mol Subcell Biol 1998; 20: 101-42.
    • (1998) Prog Mol Subcell Biol , vol.20 , pp. 101-142
    • Leaman, D.W.1
  • 5
    • 0032526030 scopus 로고    scopus 로고
    • Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons
    • Pfeffer LM, Dinarello CA, Herberman RB et al. Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons. Cancer Res 1998; 58: 2489-99.
    • (1998) Cancer Res , vol.58 , pp. 2489-2499
    • Pfeffer, L.M.1    Dinarello, C.A.2    Herberman, R.B.3
  • 6
    • 0031915601 scopus 로고    scopus 로고
    • Safety profile of interferon-α therapy
    • Weiss K. Safety profile of interferon-α therapy. Semin Oncol 1998; 25: 9-13.
    • (1998) Semin Oncol , vol.25 , pp. 9-13
    • Weiss, K.1
  • 7
    • 21344467289 scopus 로고    scopus 로고
    • Biological activity of interleukins-28 and -29: comparison with type I interferons
    • Meager A, Visvalingam K, Dilger P, Bryan D, Wadhwa M. Biological activity of interleukins-28 and -29: comparison with type I interferons. Cytokine 2005; 31: 109-18.
    • (2005) Cytokine , vol.31 , pp. 109-118
    • Meager, A.1    Visvalingam, K.2    Dilger, P.3    Bryan, D.4    Wadhwa, M.5
  • 8
    • 27444432552 scopus 로고    scopus 로고
    • IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression
    • Brand S, Beigel F, Olszak T et al. IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression. Am J Physiol Gastrointest Liver Physiol 2005; 289: G960-8.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Brand, S.1    Beigel, F.2    Olszak, T.3
  • 9
    • 33646184947 scopus 로고    scopus 로고
    • Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells
    • Zitzmann K, Brand S, Baehs S et al. Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells. Biochem Biophys Res Commun 2006; 344: 1334-41.
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 1334-1341
    • Zitzmann, K.1    Brand, S.2    Baehs, S.3
  • 10
    • 71049171694 scopus 로고    scopus 로고
    • Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents
    • Li Q, Kawamura K, Ma G et al. Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents. Eur J Cancer 2010; 46: 180-90.
    • (2010) Eur J Cancer , vol.46 , pp. 180-190
    • Li, Q.1    Kawamura, K.2    Ma, G.3
  • 11
    • 76649134095 scopus 로고    scopus 로고
    • Interleukin-29 binds to melanoma cells inducing Jak-STAT signal transduction and apoptosis
    • Guenterberg KD, Grignol VP, Raig ET et al. Interleukin-29 binds to melanoma cells inducing Jak-STAT signal transduction and apoptosis. Mol Cancer Ther 2010; 9: 510-20.
    • (2010) Mol Cancer Ther , vol.9 , pp. 510-520
    • Guenterberg, K.D.1    Grignol, V.P.2    Raig, E.T.3
  • 12
    • 47949127385 scopus 로고    scopus 로고
    • IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity
    • Maher SG, Sheikh F, Scarzello AJ et al. IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity. Cancer Biol Ther 2008; 7: 1109-15.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1109-1115
    • Maher, S.G.1    Sheikh, F.2    Scarzello, A.J.3
  • 13
    • 77955886364 scopus 로고    scopus 로고
    • Interferon-lambda as a potential therapeutic agent in cancer treatment
    • Steen HC, Gamero AM. Interferon-lambda as a potential therapeutic agent in cancer treatment. J Interferon Cytokine Res 2010; 30: 597-602.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 597-602
    • Steen, H.C.1    Gamero, A.M.2
  • 14
    • 33646242995 scopus 로고    scopus 로고
    • Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma
    • Lasfar A, Lewis-Antes A, Smirnov SV et al. Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma. Cancer Res 2006; 66: 4468-77.
    • (2006) Cancer Res , vol.66 , pp. 4468-4477
    • Lasfar, A.1    Lewis-Antes, A.2    Smirnov, S.V.3
  • 15
  • 16
    • 34247095694 scopus 로고    scopus 로고
    • IL-28 elicits antitumor responses against murine fibrosarcoma
    • Numasaki M, Tagawa M, Iwata F et al. IL-28 elicits antitumor responses against murine fibrosarcoma. J Immunol 2007; 178: 5086-98.
    • (2007) J Immunol , vol.178 , pp. 5086-5098
    • Numasaki, M.1    Tagawa, M.2    Iwata, F.3
  • 17
    • 77953044883 scopus 로고    scopus 로고
    • Antitumor activity of type I and type III interferons in BNL hepatoma model
    • Abushahba W, Balan M, Castaneda I et al. Antitumor activity of type I and type III interferons in BNL hepatoma model. Cancer Immunol Immunother 2010; 59: 1059-71.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 1059-1071
    • Abushahba, W.1    Balan, M.2    Castaneda, I.3
  • 18
    • 27144449330 scopus 로고    scopus 로고
    • IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
    • Numasaki M, Watanabe M, Suzuki T et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol 2005; 175: 6177-89.
    • (2005) J Immunol , vol.175 , pp. 6177-6189
    • Numasaki, M.1    Watanabe, M.2    Suzuki, T.3
  • 19
    • 4243105077 scopus 로고    scopus 로고
    • IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells
    • Fujiwara H, Yamakuni T, Ueno M et al. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells. J Pharmacol Exp Ther 2004; 310: 1288-95.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 1288-1295
    • Fujiwara, H.1    Yamakuni, T.2    Ueno, M.3
  • 20
    • 0033566988 scopus 로고    scopus 로고
    • Antitumor effects of interferon-omega: in vivo therapy of human tumor xenografts in nude mice
    • Horton HM, Hernandez P, Parker SE, Barnhart KM. Antitumor effects of interferon-omega: in vivo therapy of human tumor xenografts in nude mice. Cancer Res 1999; 59: 4064-8.
    • (1999) Cancer Res , vol.59 , pp. 4064-4068
    • Horton, H.M.1    Hernandez, P.2    Parker, S.E.3    Barnhart, K.M.4
  • 21
    • 0037525761 scopus 로고    scopus 로고
    • Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma
    • Seki K, Yoshikawa H, Shiiki K, Hamada Y, Akamatsu N, Takeda K. Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma. Cancer Chemother Pharmacol 2000; 45: 199-206.
    • (2000) Cancer Chemother Pharmacol , vol.45 , pp. 199-206
    • Seki, K.1    Yoshikawa, H.2    Shiiki, K.3    Hamada, Y.4    Akamatsu, N.5    Takeda, K.6
  • 22
    • 11244318660 scopus 로고    scopus 로고
    • Gene transfer-mediated pre-mRNA segmental trans-splicing as a strategy to deliver intracellular toxins for cancer therapy
    • Nakayama K, Pergolizzi RG, Crystal RG. Gene transfer-mediated pre-mRNA segmental trans-splicing as a strategy to deliver intracellular toxins for cancer therapy. Cancer Res 2004; 65: 254-63.
    • (2004) Cancer Res , vol.65 , pp. 254-263
    • Nakayama, K.1    Pergolizzi, R.G.2    Crystal, R.G.3
  • 23
    • 0034897703 scopus 로고    scopus 로고
    • 2 phase with accumulation of mitotic cyclins
    • 2 phase with accumulation of mitotic cyclins. J Virol 2001; 75: 7555-63.
    • (2001) J Virol , vol.75 , pp. 7555-7563
    • Morita, E.1    Tada, K.2    Chisaka, H.3
  • 24
    • 0037849915 scopus 로고    scopus 로고
    • Interleukin-17 promotes angiogenesis and tumor growth
    • Numasaki M, Fukushi J, Ono M et al. Interleukin-17 promotes angiogenesis and tumor growth. Blood 2003; 101: 2620-7.
    • (2003) Blood , vol.101 , pp. 2620-2627
    • Numasaki, M.1    Fukushi, J.2    Ono, M.3
  • 25
    • 0024831453 scopus 로고
    • Constitutive expression of a 2',5'-oligoadenylate synthetase cDNA results in increased antiviral activity and growth suppression
    • Rysiecki G, Gewert DR, Williams BR. Constitutive expression of a 2', 5'-oligoadenylate synthetase cDNA results in increased antiviral activity and growth suppression. J Interferon Res 1989; 9: 649-57.
    • (1989) J Interferon Res , vol.9 , pp. 649-657
    • Rysiecki, G.1    Gewert, D.R.2    Williams, B.R.3
  • 26
    • 0026701570 scopus 로고
    • Malignant transformation by a mutation of the IFN-inducible dsRNA-dependent protein kinase
    • Koromilas AE, Roy S, Barber GN, Katze MG, Sonenberg N. Malignant transformation by a mutation of the IFN-inducible dsRNA-dependent protein kinase. Science 1992; 257: 1685-9.
    • (1992) Science , vol.257 , pp. 1685-1689
    • Koromilas, A.E.1    Roy, S.2    Barber, G.N.3    Katze, M.G.4    Sonenberg, N.5
  • 27
    • 0027270867 scopus 로고
    • A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon
    • Hassel BA, Zhou A, Sotomayor C, Maran A, Silverman RH. A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon. EMBO J 1993; 12: 3297-304.
    • (1993) EMBO J , vol.12 , pp. 3297-3304
    • Hassel, B.A.1    Zhou, A.2    Sotomayor, C.3    Maran, A.4    Silverman, R.H.5
  • 28
    • 0030664277 scopus 로고    scopus 로고
    • PKR-α protein kinase regulated by double-stranded RNA
    • Clemens MJ. PKR-α protein kinase regulated by double-stranded RNA. Int J Biochem Cell Biol 1997; 29: 945-9.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 945-949
    • Clemens, M.J.1
  • 29
    • 0037293541 scopus 로고    scopus 로고
    • NF-kappa B-mediated induction of p21(Cip1/Waf1) by tumor necrosis factor alpha induces growth arrest and cytoprotection in normal human keratinocytes
    • Basile JR, Eichten A, Zacny V, Munger K. NF-kappa B-mediated induction of p21(Cip1/Waf1) by tumor necrosis factor alpha induces growth arrest and cytoprotection in normal human keratinocytes. Mol Cancer Res 2003; 1: 262-70.
    • (2003) Mol Cancer Res , vol.1 , pp. 262-270
    • Basile, J.R.1    Eichten, A.2    Zacny, V.3    Munger, K.4
  • 30
    • 0030027049 scopus 로고    scopus 로고
    • Dependence of cyclin E-CDK2 kinase activity on cell anchorage
    • Fang F, Orend G, Watanabe N, Hunter T, Ruoslahti E. Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science 1996; 271: 499-502.
    • (1996) Science , vol.271 , pp. 499-502
    • Fang, F.1    Orend, G.2    Watanabe, N.3    Hunter, T.4    Ruoslahti, E.5
  • 31
    • 0032190833 scopus 로고    scopus 로고
    • Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression
    • Bates S, Ryan KM, Phillips AC, Vousden KH. Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression. Oncogene 1998; 17: 1691-703.
    • (1998) Oncogene , vol.17 , pp. 1691-1703
    • Bates, S.1    Ryan, K.M.2    Phillips, A.C.3    Vousden, K.H.4
  • 32
    • 14944355723 scopus 로고    scopus 로고
    • Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2
    • Tsukada Y, Tanaka T, Miyazawa K, Kitamura N. Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2. J Biochem 2004; 136: 701-9.
    • (2004) J Biochem , vol.136 , pp. 701-709
    • Tsukada, Y.1    Tanaka, T.2    Miyazawa, K.3    Kitamura, N.4
  • 33
    • 0033975549 scopus 로고    scopus 로고
    • The growth inhibitory effect of p21 adenovirus on human bladder cancer cells
    • Hall MC, Li Y, Pong RC, Ely B, Sagalowsky AI, Hsieh JT. The growth inhibitory effect of p21 adenovirus on human bladder cancer cells. J Urol 2000; 163: 1033-8.
    • (2000) J Urol , vol.163 , pp. 1033-1038
    • Hall, M.C.1    Li, Y.2    Pong, R.C.3    Ely, B.4    Sagalowsky, A.I.5    Hsieh, J.T.6
  • 34
    • 0033925683 scopus 로고    scopus 로고
    • Growth inhibition of human glioma cells by transfection-induced p21 and its effects on telomerase activity
    • Harada K, Kurisu K, Sadatomo T et al. Growth inhibition of human glioma cells by transfection-induced p21 and its effects on telomerase activity. J Neurooncol 2000; 47: 39-46.
    • (2000) J Neurooncol , vol.47 , pp. 39-46
    • Harada, K.1    Kurisu, K.2    Sadatomo, T.3
  • 36
    • 0033529122 scopus 로고    scopus 로고
    • Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins
    • Sangfelt O, Erickson S, Castro J et al. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins. Oncogene 1999; 18: 2798-810.
    • (1999) Oncogene , vol.18 , pp. 2798-2810
    • Sangfelt, O.1    Erickson, S.2    Castro, J.3
  • 37
    • 24744438238 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells
    • Han J, Tsukada Y, Hara E, Kitamura N, Tanaka T. Hepatocyte growth factor induces redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells. J Biol Chem 2005; 280: 31548-56.
    • (2005) J Biol Chem , vol.280 , pp. 31548-31556
    • Han, J.1    Tsukada, Y.2    Hara, E.3    Kitamura, N.4    Tanaka, T.5
  • 38
    • 0032569736 scopus 로고    scopus 로고
    • Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression
    • Vonlanthen S, Heighway J, Tschan MP et al. Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression. Oncogene 1998; 17: 2779-85.
    • (1998) Oncogene , vol.17 , pp. 2779-2785
    • Vonlanthen, S.1    Heighway, J.2    Tschan, M.P.3
  • 39
    • 0029665043 scopus 로고    scopus 로고
    • Rb and p16INK4a expression in resected non-small cell lung tumors
    • Kratzke RA, Greatens TM, Rubins JB et al. Rb and p16INK4a expression in resected non-small cell lung tumors. Cancer Res 1996; 56: 3415-20.
    • (1996) Cancer Res , vol.56 , pp. 3415-3420
    • Kratzke, R.A.1    Greatens, T.M.2    Rubins, J.B.3
  • 40
    • 0030765323 scopus 로고    scopus 로고
    • Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma
    • Taga S, Osaki T, Ohgami A et al. Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma. Cancer 1997; 80: 389-95.
    • (1997) Cancer , vol.80 , pp. 389-395
    • Taga, S.1    Osaki, T.2    Ohgami, A.3
  • 41
    • 0031029580 scopus 로고    scopus 로고
    • Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines
    • Sangfelt O, Erickson S, Einhorn S, Grander D. Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines. Oncogene 1997; 14: 415-33.
    • (1997) Oncogene , vol.14 , pp. 415-433
    • Sangfelt, O.1    Erickson, S.2    Einhorn, S.3    Grander, D.4
  • 42
    • 0031772069 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 gene abnormality and loss of growth inhibitory effect of interferon-alpha in human hepatoma cell lines
    • Tada S, Saito H, Tsunematsu S et al. Interferon regulatory factor-1 gene abnormality and loss of growth inhibitory effect of interferon-alpha in human hepatoma cell lines. Int J Oncol 1998; 13: 1207-16.
    • (1998) Int J Oncol , vol.13 , pp. 1207-1216
    • Tada, S.1    Saito, H.2    Tsunematsu, S.3
  • 43
    • 0032576887 scopus 로고    scopus 로고
    • Differential expression of the p27Kip1 mRNA in IFN-sensitive and resistant cell lines
    • Moro A, Calixto A, Suarez E, Arana MJ, Perea SE. Differential expression of the p27Kip1 mRNA in IFN-sensitive and resistant cell lines. Biochem Biophys Res Commun 1998; 245: 752-6.
    • (1998) Biochem Biophys Res Commun , vol.245 , pp. 752-756
    • Moro, A.1    Calixto, A.2    Suarez, E.3    Arana, M.J.4    Perea, S.E.5
  • 44
    • 0023160237 scopus 로고
    • Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses
    • Sidky YA, Borden EC. Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses. Cancer Res 1987; 47: 5155-61.
    • (1987) Cancer Res , vol.47 , pp. 5155-5161
    • Sidky, Y.A.1    Borden, E.C.2
  • 45
    • 0030747031 scopus 로고    scopus 로고
    • p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung
    • Komiya T, Hosono Y, Hirashima T et al. p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung. Clin Cancer Res 1997; 3: 1831-5.
    • (1997) Clin Cancer Res , vol.3 , pp. 1831-1835
    • Komiya, T.1    Hosono, Y.2    Hirashima, T.3
  • 46
    • 0037106265 scopus 로고    scopus 로고
    • Clinical significance of p21 expression in non-small cell lung cancer
    • Shoji T, Tanaka F, Takata T et al. Clinical significance of p21 expression in non-small cell lung cancer. J Clin Oncol 2002; 20: 3865-71.
    • (2002) J Clin Oncol , vol.20 , pp. 3865-3871
    • Shoji, T.1    Tanaka, F.2    Takata, T.3
  • 47
    • 20344400638 scopus 로고    scopus 로고
    • Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review
    • Singhal S, Vachani A, Antin-Ozerkis D, Kaiser LR, Albelda SM. Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review. Clin Cancer Res 2005; 11: 3974-86.
    • (2005) Clin Cancer Res , vol.11 , pp. 3974-3986
    • Singhal, S.1    Vachani, A.2    Antin-Ozerkis, D.3    Kaiser, L.R.4    Albelda, S.M.5
  • 48
    • 79952130188 scopus 로고    scopus 로고
    • IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression
    • Liu BS, Janssen HL, Boonstra A. IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression. Blood 2011; 117: 2385-95.
    • (2011) Blood , vol.117 , pp. 2385-2395
    • Liu, B.S.1    Janssen, H.L.2    Boonstra, A.3


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