-
1
-
-
0037232131
-
Novel interferons
-
Vilcek J. Novel interferons. Nat Immunol 2003; 4: 8-9.
-
(2003)
Nat Immunol
, vol.4
, pp. 8-9
-
-
Vilcek, J.1
-
2
-
-
0037236826
-
IL-28, IL-29 and their class II cytokine receptor IL-28R
-
Sheppard P, Kindsvogel W, Xu W et al. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat Immunol 2003; 4: 63-8.
-
(2003)
Nat Immunol
, vol.4
, pp. 63-68
-
-
Sheppard, P.1
Kindsvogel, W.2
Xu, W.3
-
3
-
-
0037243222
-
IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
-
Kotenko SV, Gallagher G, Baurin VV et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol 2003; 4: 69-77.
-
(2003)
Nat Immunol
, vol.4
, pp. 69-77
-
-
Kotenko, S.V.1
Gallagher, G.2
Baurin, V.V.3
-
4
-
-
0032232899
-
Mechanism of interferon action
-
Leaman DW. Mechanism of interferon action. Prog Mol Subcell Biol 1998; 20: 101-42.
-
(1998)
Prog Mol Subcell Biol
, vol.20
, pp. 101-142
-
-
Leaman, D.W.1
-
5
-
-
0032526030
-
Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons
-
Pfeffer LM, Dinarello CA, Herberman RB et al. Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons. Cancer Res 1998; 58: 2489-99.
-
(1998)
Cancer Res
, vol.58
, pp. 2489-2499
-
-
Pfeffer, L.M.1
Dinarello, C.A.2
Herberman, R.B.3
-
6
-
-
0031915601
-
Safety profile of interferon-α therapy
-
Weiss K. Safety profile of interferon-α therapy. Semin Oncol 1998; 25: 9-13.
-
(1998)
Semin Oncol
, vol.25
, pp. 9-13
-
-
Weiss, K.1
-
7
-
-
21344467289
-
Biological activity of interleukins-28 and -29: comparison with type I interferons
-
Meager A, Visvalingam K, Dilger P, Bryan D, Wadhwa M. Biological activity of interleukins-28 and -29: comparison with type I interferons. Cytokine 2005; 31: 109-18.
-
(2005)
Cytokine
, vol.31
, pp. 109-118
-
-
Meager, A.1
Visvalingam, K.2
Dilger, P.3
Bryan, D.4
Wadhwa, M.5
-
8
-
-
27444432552
-
IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression
-
Brand S, Beigel F, Olszak T et al. IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression. Am J Physiol Gastrointest Liver Physiol 2005; 289: G960-8.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Brand, S.1
Beigel, F.2
Olszak, T.3
-
9
-
-
33646184947
-
Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells
-
Zitzmann K, Brand S, Baehs S et al. Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells. Biochem Biophys Res Commun 2006; 344: 1334-41.
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 1334-1341
-
-
Zitzmann, K.1
Brand, S.2
Baehs, S.3
-
10
-
-
71049171694
-
Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents
-
Li Q, Kawamura K, Ma G et al. Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents. Eur J Cancer 2010; 46: 180-90.
-
(2010)
Eur J Cancer
, vol.46
, pp. 180-190
-
-
Li, Q.1
Kawamura, K.2
Ma, G.3
-
11
-
-
76649134095
-
Interleukin-29 binds to melanoma cells inducing Jak-STAT signal transduction and apoptosis
-
Guenterberg KD, Grignol VP, Raig ET et al. Interleukin-29 binds to melanoma cells inducing Jak-STAT signal transduction and apoptosis. Mol Cancer Ther 2010; 9: 510-20.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 510-520
-
-
Guenterberg, K.D.1
Grignol, V.P.2
Raig, E.T.3
-
12
-
-
47949127385
-
IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity
-
Maher SG, Sheikh F, Scarzello AJ et al. IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity. Cancer Biol Ther 2008; 7: 1109-15.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1109-1115
-
-
Maher, S.G.1
Sheikh, F.2
Scarzello, A.J.3
-
13
-
-
77955886364
-
Interferon-lambda as a potential therapeutic agent in cancer treatment
-
Steen HC, Gamero AM. Interferon-lambda as a potential therapeutic agent in cancer treatment. J Interferon Cytokine Res 2010; 30: 597-602.
-
(2010)
J Interferon Cytokine Res
, vol.30
, pp. 597-602
-
-
Steen, H.C.1
Gamero, A.M.2
-
14
-
-
33646242995
-
Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma
-
Lasfar A, Lewis-Antes A, Smirnov SV et al. Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma. Cancer Res 2006; 66: 4468-77.
-
(2006)
Cancer Res
, vol.66
, pp. 4468-4477
-
-
Lasfar, A.1
Lewis-Antes, A.2
Smirnov, S.V.3
-
15
-
-
33744910591
-
Antitumor activity of IFN-lambda in murine tumor models
-
Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T. Antitumor activity of IFN-lambda in murine tumor models. J Immunol 2006; 176: 7686-94.
-
(2006)
J Immunol
, vol.176
, pp. 7686-7694
-
-
Sato, A.1
Ohtsuki, M.2
Hata, M.3
Kobayashi, E.4
Murakami, T.5
-
16
-
-
34247095694
-
IL-28 elicits antitumor responses against murine fibrosarcoma
-
Numasaki M, Tagawa M, Iwata F et al. IL-28 elicits antitumor responses against murine fibrosarcoma. J Immunol 2007; 178: 5086-98.
-
(2007)
J Immunol
, vol.178
, pp. 5086-5098
-
-
Numasaki, M.1
Tagawa, M.2
Iwata, F.3
-
17
-
-
77953044883
-
Antitumor activity of type I and type III interferons in BNL hepatoma model
-
Abushahba W, Balan M, Castaneda I et al. Antitumor activity of type I and type III interferons in BNL hepatoma model. Cancer Immunol Immunother 2010; 59: 1059-71.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1059-1071
-
-
Abushahba, W.1
Balan, M.2
Castaneda, I.3
-
18
-
-
27144449330
-
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
-
Numasaki M, Watanabe M, Suzuki T et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol 2005; 175: 6177-89.
-
(2005)
J Immunol
, vol.175
, pp. 6177-6189
-
-
Numasaki, M.1
Watanabe, M.2
Suzuki, T.3
-
19
-
-
4243105077
-
IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells
-
Fujiwara H, Yamakuni T, Ueno M et al. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells. J Pharmacol Exp Ther 2004; 310: 1288-95.
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 1288-1295
-
-
Fujiwara, H.1
Yamakuni, T.2
Ueno, M.3
-
20
-
-
0033566988
-
Antitumor effects of interferon-omega: in vivo therapy of human tumor xenografts in nude mice
-
Horton HM, Hernandez P, Parker SE, Barnhart KM. Antitumor effects of interferon-omega: in vivo therapy of human tumor xenografts in nude mice. Cancer Res 1999; 59: 4064-8.
-
(1999)
Cancer Res
, vol.59
, pp. 4064-4068
-
-
Horton, H.M.1
Hernandez, P.2
Parker, S.E.3
Barnhart, K.M.4
-
21
-
-
0037525761
-
Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma
-
Seki K, Yoshikawa H, Shiiki K, Hamada Y, Akamatsu N, Takeda K. Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma. Cancer Chemother Pharmacol 2000; 45: 199-206.
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 199-206
-
-
Seki, K.1
Yoshikawa, H.2
Shiiki, K.3
Hamada, Y.4
Akamatsu, N.5
Takeda, K.6
-
22
-
-
11244318660
-
Gene transfer-mediated pre-mRNA segmental trans-splicing as a strategy to deliver intracellular toxins for cancer therapy
-
Nakayama K, Pergolizzi RG, Crystal RG. Gene transfer-mediated pre-mRNA segmental trans-splicing as a strategy to deliver intracellular toxins for cancer therapy. Cancer Res 2004; 65: 254-63.
-
(2004)
Cancer Res
, vol.65
, pp. 254-263
-
-
Nakayama, K.1
Pergolizzi, R.G.2
Crystal, R.G.3
-
23
-
-
0034897703
-
2 phase with accumulation of mitotic cyclins
-
2 phase with accumulation of mitotic cyclins. J Virol 2001; 75: 7555-63.
-
(2001)
J Virol
, vol.75
, pp. 7555-7563
-
-
Morita, E.1
Tada, K.2
Chisaka, H.3
-
24
-
-
0037849915
-
Interleukin-17 promotes angiogenesis and tumor growth
-
Numasaki M, Fukushi J, Ono M et al. Interleukin-17 promotes angiogenesis and tumor growth. Blood 2003; 101: 2620-7.
-
(2003)
Blood
, vol.101
, pp. 2620-2627
-
-
Numasaki, M.1
Fukushi, J.2
Ono, M.3
-
25
-
-
0024831453
-
Constitutive expression of a 2',5'-oligoadenylate synthetase cDNA results in increased antiviral activity and growth suppression
-
Rysiecki G, Gewert DR, Williams BR. Constitutive expression of a 2', 5'-oligoadenylate synthetase cDNA results in increased antiviral activity and growth suppression. J Interferon Res 1989; 9: 649-57.
-
(1989)
J Interferon Res
, vol.9
, pp. 649-657
-
-
Rysiecki, G.1
Gewert, D.R.2
Williams, B.R.3
-
26
-
-
0026701570
-
Malignant transformation by a mutation of the IFN-inducible dsRNA-dependent protein kinase
-
Koromilas AE, Roy S, Barber GN, Katze MG, Sonenberg N. Malignant transformation by a mutation of the IFN-inducible dsRNA-dependent protein kinase. Science 1992; 257: 1685-9.
-
(1992)
Science
, vol.257
, pp. 1685-1689
-
-
Koromilas, A.E.1
Roy, S.2
Barber, G.N.3
Katze, M.G.4
Sonenberg, N.5
-
27
-
-
0027270867
-
A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon
-
Hassel BA, Zhou A, Sotomayor C, Maran A, Silverman RH. A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon. EMBO J 1993; 12: 3297-304.
-
(1993)
EMBO J
, vol.12
, pp. 3297-3304
-
-
Hassel, B.A.1
Zhou, A.2
Sotomayor, C.3
Maran, A.4
Silverman, R.H.5
-
28
-
-
0030664277
-
PKR-α protein kinase regulated by double-stranded RNA
-
Clemens MJ. PKR-α protein kinase regulated by double-stranded RNA. Int J Biochem Cell Biol 1997; 29: 945-9.
-
(1997)
Int J Biochem Cell Biol
, vol.29
, pp. 945-949
-
-
Clemens, M.J.1
-
29
-
-
0037293541
-
NF-kappa B-mediated induction of p21(Cip1/Waf1) by tumor necrosis factor alpha induces growth arrest and cytoprotection in normal human keratinocytes
-
Basile JR, Eichten A, Zacny V, Munger K. NF-kappa B-mediated induction of p21(Cip1/Waf1) by tumor necrosis factor alpha induces growth arrest and cytoprotection in normal human keratinocytes. Mol Cancer Res 2003; 1: 262-70.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 262-270
-
-
Basile, J.R.1
Eichten, A.2
Zacny, V.3
Munger, K.4
-
30
-
-
0030027049
-
Dependence of cyclin E-CDK2 kinase activity on cell anchorage
-
Fang F, Orend G, Watanabe N, Hunter T, Ruoslahti E. Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science 1996; 271: 499-502.
-
(1996)
Science
, vol.271
, pp. 499-502
-
-
Fang, F.1
Orend, G.2
Watanabe, N.3
Hunter, T.4
Ruoslahti, E.5
-
31
-
-
0032190833
-
Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression
-
Bates S, Ryan KM, Phillips AC, Vousden KH. Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression. Oncogene 1998; 17: 1691-703.
-
(1998)
Oncogene
, vol.17
, pp. 1691-1703
-
-
Bates, S.1
Ryan, K.M.2
Phillips, A.C.3
Vousden, K.H.4
-
32
-
-
14944355723
-
Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2
-
Tsukada Y, Tanaka T, Miyazawa K, Kitamura N. Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2. J Biochem 2004; 136: 701-9.
-
(2004)
J Biochem
, vol.136
, pp. 701-709
-
-
Tsukada, Y.1
Tanaka, T.2
Miyazawa, K.3
Kitamura, N.4
-
33
-
-
0033975549
-
The growth inhibitory effect of p21 adenovirus on human bladder cancer cells
-
Hall MC, Li Y, Pong RC, Ely B, Sagalowsky AI, Hsieh JT. The growth inhibitory effect of p21 adenovirus on human bladder cancer cells. J Urol 2000; 163: 1033-8.
-
(2000)
J Urol
, vol.163
, pp. 1033-1038
-
-
Hall, M.C.1
Li, Y.2
Pong, R.C.3
Ely, B.4
Sagalowsky, A.I.5
Hsieh, J.T.6
-
34
-
-
0033925683
-
Growth inhibition of human glioma cells by transfection-induced p21 and its effects on telomerase activity
-
Harada K, Kurisu K, Sadatomo T et al. Growth inhibition of human glioma cells by transfection-induced p21 and its effects on telomerase activity. J Neurooncol 2000; 47: 39-46.
-
(2000)
J Neurooncol
, vol.47
, pp. 39-46
-
-
Harada, K.1
Kurisu, K.2
Sadatomo, T.3
-
36
-
-
0033529122
-
Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins
-
Sangfelt O, Erickson S, Castro J et al. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins. Oncogene 1999; 18: 2798-810.
-
(1999)
Oncogene
, vol.18
, pp. 2798-2810
-
-
Sangfelt, O.1
Erickson, S.2
Castro, J.3
-
37
-
-
24744438238
-
Hepatocyte growth factor induces redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells
-
Han J, Tsukada Y, Hara E, Kitamura N, Tanaka T. Hepatocyte growth factor induces redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells. J Biol Chem 2005; 280: 31548-56.
-
(2005)
J Biol Chem
, vol.280
, pp. 31548-31556
-
-
Han, J.1
Tsukada, Y.2
Hara, E.3
Kitamura, N.4
Tanaka, T.5
-
38
-
-
0032569736
-
Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression
-
Vonlanthen S, Heighway J, Tschan MP et al. Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression. Oncogene 1998; 17: 2779-85.
-
(1998)
Oncogene
, vol.17
, pp. 2779-2785
-
-
Vonlanthen, S.1
Heighway, J.2
Tschan, M.P.3
-
39
-
-
0029665043
-
Rb and p16INK4a expression in resected non-small cell lung tumors
-
Kratzke RA, Greatens TM, Rubins JB et al. Rb and p16INK4a expression in resected non-small cell lung tumors. Cancer Res 1996; 56: 3415-20.
-
(1996)
Cancer Res
, vol.56
, pp. 3415-3420
-
-
Kratzke, R.A.1
Greatens, T.M.2
Rubins, J.B.3
-
40
-
-
0030765323
-
Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma
-
Taga S, Osaki T, Ohgami A et al. Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma. Cancer 1997; 80: 389-95.
-
(1997)
Cancer
, vol.80
, pp. 389-395
-
-
Taga, S.1
Osaki, T.2
Ohgami, A.3
-
41
-
-
0031029580
-
Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines
-
Sangfelt O, Erickson S, Einhorn S, Grander D. Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines. Oncogene 1997; 14: 415-33.
-
(1997)
Oncogene
, vol.14
, pp. 415-433
-
-
Sangfelt, O.1
Erickson, S.2
Einhorn, S.3
Grander, D.4
-
42
-
-
0031772069
-
Interferon regulatory factor-1 gene abnormality and loss of growth inhibitory effect of interferon-alpha in human hepatoma cell lines
-
Tada S, Saito H, Tsunematsu S et al. Interferon regulatory factor-1 gene abnormality and loss of growth inhibitory effect of interferon-alpha in human hepatoma cell lines. Int J Oncol 1998; 13: 1207-16.
-
(1998)
Int J Oncol
, vol.13
, pp. 1207-1216
-
-
Tada, S.1
Saito, H.2
Tsunematsu, S.3
-
43
-
-
0032576887
-
Differential expression of the p27Kip1 mRNA in IFN-sensitive and resistant cell lines
-
Moro A, Calixto A, Suarez E, Arana MJ, Perea SE. Differential expression of the p27Kip1 mRNA in IFN-sensitive and resistant cell lines. Biochem Biophys Res Commun 1998; 245: 752-6.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 752-756
-
-
Moro, A.1
Calixto, A.2
Suarez, E.3
Arana, M.J.4
Perea, S.E.5
-
44
-
-
0023160237
-
Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses
-
Sidky YA, Borden EC. Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses. Cancer Res 1987; 47: 5155-61.
-
(1987)
Cancer Res
, vol.47
, pp. 5155-5161
-
-
Sidky, Y.A.1
Borden, E.C.2
-
45
-
-
0030747031
-
p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung
-
Komiya T, Hosono Y, Hirashima T et al. p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung. Clin Cancer Res 1997; 3: 1831-5.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1831-1835
-
-
Komiya, T.1
Hosono, Y.2
Hirashima, T.3
-
46
-
-
0037106265
-
Clinical significance of p21 expression in non-small cell lung cancer
-
Shoji T, Tanaka F, Takata T et al. Clinical significance of p21 expression in non-small cell lung cancer. J Clin Oncol 2002; 20: 3865-71.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3865-3871
-
-
Shoji, T.1
Tanaka, F.2
Takata, T.3
-
47
-
-
20344400638
-
Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review
-
Singhal S, Vachani A, Antin-Ozerkis D, Kaiser LR, Albelda SM. Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review. Clin Cancer Res 2005; 11: 3974-86.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3974-3986
-
-
Singhal, S.1
Vachani, A.2
Antin-Ozerkis, D.3
Kaiser, L.R.4
Albelda, S.M.5
-
48
-
-
79952130188
-
IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression
-
Liu BS, Janssen HL, Boonstra A. IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression. Blood 2011; 117: 2385-95.
-
(2011)
Blood
, vol.117
, pp. 2385-2395
-
-
Liu, B.S.1
Janssen, H.L.2
Boonstra, A.3
|