메뉴 건너뛰기




Volumn 33, Issue 4, 2013, Pages 1429-1438

Thrombospondin-1 receptor mediates autophagy of RAS-expressing cancer cells and triggers tumour growth inhibition

Author keywords

4N1K; Autophagy; Cancer; CD36; CD47; TSP 1

Indexed keywords

4N1K PEPTIDE; ACRIDINE ORANGE; ANTINEOPLASTIC AGENT; CASPASE 3; CD36 ANTIGEN; CD47 ANTIBODY; CD47 ANTIGEN; CELL ANTIBODY; PEPTIDE; RAS PROTEIN; THROMBOSPONDIN 1; UNCLASSIFIED DRUG;

EID: 84876771337     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (43)
  • 1
    • 10344220521 scopus 로고    scopus 로고
    • Endogenous angiogenesis inhibitors
    • DOI 10.1111/j.1600-0463.2004.apm11207-0809.x
    • Folkman J: Endogenous angiogenesis inhibitors. Apmis 112: 496-507, 2004. (Pubitemid 39626056)
    • (2004) APMIS , vol.112 , Issue.7-8 , pp. 496-507
    • Folkman, J.1
  • 3
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • DOI 10.1016/S1535-6108(03)00030-8
    • Watnick RS, Cheng Y-N, Rangarajan A, Ince TA and Weinberg RA: Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell 3: 219-231, 2003. (Pubitemid 37443878)
    • (2003) Cancer Cell , vol.3 , Issue.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.-N.2    Rangarajan, A.3    Ince, T.A.4    Weinberg, R.A.5
  • 4
    • 25444449494 scopus 로고    scopus 로고
    • Oncogenes and angiogenesis: Down-regulation of thrombospondin-1 in normal fibroblasts exposed to factors from cancer cells harboring mutant ras
    • DOI 10.1158/0008-5472.CAN-05-1479
    • Kalas W, Yu JL, Milsom C, Rosenfeld J, Benezra R, Bornstein P and Rak J: Oncogenes and Angiogenesis: down-regulation of thrombospondin-1 in normal fibroblasts exposed to factors from cancer cells harboring mutant ras. Cancer Res 65: 8878-8886, 2005. (Pubitemid 41377377)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8878-8886
    • Kalas, W.1    Yu, J.L.2    Milsom, C.3    Rosenfeld, J.4    Benezra, R.5    Bornstein, P.6    Rak, J.7
  • 5
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron KM, Volpert OV, Tainsky MA and Bouck N: Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265: 1582-1584, 1994. (Pubitemid 24308973)
    • (1994) Science , vol.265 , Issue.5178 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 6
    • 0028089956 scopus 로고
    • Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma
    • DOI 10.1002/ijc.2910590209
    • Zabrenetzky V, Harris CC, Steeg PS and Roberts DD: Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines. Int J Cancer 59: 191-195, 1994. (Pubitemid 24343361)
    • (1994) International Journal of Cancer , vol.59 , Issue.2 , pp. 191-195
    • Zabrenetzky, V.1    Harris, C.C.2    Steeg, P.S.3    Roberts, D.D.4
  • 7
    • 0342445431 scopus 로고    scopus 로고
    • Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
    • DOI 10.1038/71517
    • Jiménez B, Volpert OV, Crawford SE, Febbraio M, Silverstein RL and Bouck N: Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Nat Med 6: 41-48, 2000. (Pubitemid 30048524)
    • (2000) Nature Medicine , vol.6 , Issue.1 , pp. 41-48
    • Jimenez, B.1    Volpert, O.V.2    Crawford, S.E.3    Febbraio, M.4    Silverstein, R.L.5    Bouck, N.6
  • 8
    • 0033613226 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats
    • Iruela-Arispe ML, Lombardo M, Krutzsch HC, Lawler J and Roberts DD: Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation 100: 1423-1431, 1999. (Pubitemid 29451703)
    • (1999) Circulation , vol.100 , Issue.13 , pp. 1423-1431
    • Iruela-Arispe, M.L.1    Lombardo, M.2    Krutzsch, H.C.3    Lawler, J.4    Roberts, D.D.5
  • 9
    • 84867268459 scopus 로고    scopus 로고
    • Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2
    • Lawler PR and Lawler J: Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2. Cold Spring Harb Perspect Med 2: a006627, 2012.
    • (2012) Cold Spring Harb Perspect Med , vol.2
    • Lawler, P.R.1    Lawler, J.2
  • 10
    • 34547768293 scopus 로고    scopus 로고
    • Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle
    • DOI 10.1111/j.1349-7006.2007.00534.x
    • Yamauchi M, Imajoh-Ohmi S and Shibuya M: Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle. Cancer Sci 98: 1491-1497, 2007. (Pubitemid 47241775)
    • (2007) Cancer Science , vol.98 , Issue.9 , pp. 1491-1497
    • Yamauchi, M.1    Imajoh-ohmi, S.2    Shibuya, M.3
  • 11
    • 34548821303 scopus 로고    scopus 로고
    • Thrombospondin-based antiangiogenic therapy
    • DOI 10.1016/j.mvr.2007.04.007, PII S0026286207000532, Therapeutic Applications of Angiogenesis and Anti-angiogenesis
    • Zhang X and Lawler J: Thrombospondin-based antiangiogenic therapy. Microvasc Res 74: 90-99, 2009. (Pubitemid 350064284)
    • (2007) Microvascular Research , vol.74 , Issue.2-3 , pp. 90-99
    • Zhang, X.1    Lawler, J.2
  • 12
    • 33846228382 scopus 로고    scopus 로고
    • Preclinical evaluation of antiangiogenic thrombospondin-1 peptide mimetics, ABT-526 and ABT-510, in companion dogs with naturally occurring cancers
    • DOI 10.1158/1078-0432.CCR-06-0109
    • Rusk A, McKeegan E, Haviv F, Majest S, Henkin J and Khanna C: Preclinical evaluation of antiangiogenic thrombospondin-1 peptide mimetics, ABT-526 and ABT-510, in companion dogs with naturally occurring cancers. Clin Cancer Res 12: 7444-7455, 2006. (Pubitemid 46095420)
    • (2006) Clinical Cancer Research , vol.12 , Issue.24 , pp. 7444-7455
    • Rusk, A.1    McKeegan, E.2    Haviv, F.3    Majest, S.4    Henkin, J.5    Khanna, C.6
  • 13
    • 57649139197 scopus 로고    scopus 로고
    • A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer
    • Gordon MS, Mendelson D, Carr R, Knight RA, Humerickhouse RA, Iannone M and Stopeck AT: A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer. Cancer 113: 3420-3429, 2008.
    • (2008) Cancer , vol.113 , pp. 3420-3429
    • Gordon, M.S.1    Mendelson, D.2    Carr, R.3    Knight, R.A.4    Humerickhouse, R.A.5    Iannone, M.6    Stopeck, A.T.7
  • 14
    • 0036702030 scopus 로고    scopus 로고
    • Opposite effects of thrombospondin-1 via CD36 and CD47 on homotypic aggregation of monocytic cells
    • DOI 10.1016/S0945-053X(02)00036-7, PII S0945053X02000367
    • Yamauchi Y, Kuroki M, Imakiire T, Uno K, Abe H, Beppu R, Yamashita Y, Kuroki M and Shirakusa T: Opposite effects of thrombospondin-1 via CD36 and CD47 on homotypic aggregation of monocytic cells. Matrix Biol 21: 441-448, 2002. (Pubitemid 35286610)
    • (2002) Matrix Biology , vol.21 , Issue.5 , pp. 441-448
    • Yamauchi, Y.1    Kuroki, M.2    Imakiire, T.3    Uno, K.4    Abe, H.5    Beppu, R.6    Yamashita, Y.7    Kuroki, M.8    Shirakusa, T.9
  • 16
    • 0035280238 scopus 로고    scopus 로고
    • Integrin-associated protein (CD47) and its ligands
    • DOI 10.1016/S0962-8924(00)01906-1, PII S0962892400019061
    • Brown EJ and Frazier WA: Integrin-associated protein (CD47) and its ligands. Trends Cell Biol 11: 130-135, 2001. (Pubitemid 32289443)
    • (2001) Trends in Cell Biology , vol.11 , Issue.3 , pp. 130-135
    • Brown, E.J.1    Frazier, W.A.2
  • 18
    • 0036889434 scopus 로고    scopus 로고
    • Mechanosensitive induction of apoptosis in fibroblasts is regulated by thrombospondin-1 and integrin associated protein (CD47)
    • DOI 10.1023/A:1020634924760
    • Graf R, Freyberg M, Kaiser D and Friedl P: Mechanosensitive induction of apoptosis in fibroblasts is regulated by thrombospondin-1 and integrin associated protein (CD47). Apoptosis 7: 493-498, 2002. (Pubitemid 35334443)
    • (2002) Apoptosis , vol.7 , Issue.6 , pp. 493-498
    • Graf, R.1    Freyberg, M.2    Kaiser, D.3    Friedl, P.4
  • 20
    • 36148954660 scopus 로고    scopus 로고
    • The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer
    • DOI 10.1007/s10555-007-9080-0, Forty Years of Metastasis Research: A Tribute to Dr. Isaiah J. Fidler
    • Mellor HR and Harris AL: The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer. Cancer Metastasis Rev 26: 553-566, 2007. (Pubitemid 350115110)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.3-4 , pp. 553-566
    • Mellor, H.R.1    Harris, A.L.2
  • 22
    • 0038743077 scopus 로고    scopus 로고
    • Induction of autophagic cell death in malignant glioma cells by arsenic trioxide
    • Kanzawa T, Kondo Y, Ito H, Kondo S and Germano I: Induction of autophagic cell death in malignant glioma cells by arsenic trioxide. Cancer Res 63: 2103-2108, 2003. (Pubitemid 36538613)
    • (2003) Cancer Research , vol.63 , Issue.9 , pp. 2103-2108
    • Kanzawa, T.1    Kondo, Y.2    Ito, H.3    Kondo, S.4    Germano, I.5
  • 23
    • 55949087699 scopus 로고    scopus 로고
    • Role of the metabolic stress responses of apoptosis and autophagy in tumor suppression
    • White E: Role of the metabolic stress responses of apoptosis and autophagy in tumor suppression. Ernst Schering Found Symp Proc pp. 23-34, 2007.
    • (2007) Ernst Schering Found Symp Proc , pp. 23-34
    • White, E.1
  • 25
  • 26
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D and Weinberg RA: Hallmarks of Cancer: The Next Generation. Cell 144: 646-674, 2011.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 27
    • 0032977041 scopus 로고    scopus 로고
    • Cancer therapy based on p53
    • McCormick F: Cancer therapy based on p53. Cancer J Sci Am 5: 139-144, 2009.
    • (2009) Cancer J Sci Am , vol.5 , pp. 139-144
    • McCormick, F.1
  • 28
    • 33645879512 scopus 로고    scopus 로고
    • Targeted therapy of DNA tumor virus-associated cancers using virus-activated transcription factors
    • Lim MJ et al: Targeted therapy of DNA tumor virus-associated cancers using virus-activated transcription factors. Mol Ther 13: 899-909, 2006.
    • (2006) Mol Ther , vol.13 , pp. 899-909
    • Lim, M.J.1
  • 29
    • 44849093562 scopus 로고    scopus 로고
    • Oncogene addiction
    • Weinstein IB and Joe A: Oncogene addiction. Cancer Res 68: 3077-3080; 2008.
    • (2008) Cancer Res , vol.68 , pp. 3077-3080
    • Weinstein, I.B.1    Joe, A.2
  • 30
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • DOI 10.1038/nrc969
    • Downward J: Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3: 11-22, 2003. (Pubitemid 37328883)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.1 , pp. 11-22
    • Downward, J.1
  • 31
    • 0027905014 scopus 로고
    • Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
    • Shirasawa S, Furuse M, Yokoyama N and Sasazuki T: Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science 260: 85-88, 1993. (Pubitemid 23122749)
    • (1993) Science , vol.259 , Issue.5104 , pp. 85-88
    • Shirasawa, S.1    Furuse, M.2    Yokoyama, N.3    Sasazuki, T.4
  • 32
    • 0028910567 scopus 로고
    • Consequences of angiogenesis for tumor progression, metastasis and cancer therapy
    • Rak JW, St Croix BD and Kerbel RS: Consequences of angiogenesis for tumor progression, metastasis and cancer therapy. Anticancer Drugs 6: 3-18, 1995.
    • (1995) Anticancer Drugs , vol.6 , pp. 3-18
    • Rak, J.W.1    St. Croix, B.D.2    Kerbel, R.S.3
  • 35
    • 0033027727 scopus 로고    scopus 로고
    • Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat
    • Dawson DW, Volpert OV, Pearce SF, Schneider AJ, Silverstein RL, Henkin J and Bouck NP: Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat. Mol Pharmacol 55: 332-338, 1999. (Pubitemid 29076031)
    • (1999) Molecular Pharmacology , vol.55 , Issue.2 , pp. 332-338
    • Dawson, D.W.1    Volpert, O.V.2    Frieda A. Pearce, S.3    Schneider, A.J.4    Silverstein, R.L.5    Henkin, J.6    Bouck, N.P.7
  • 38
    • 77951228508 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy: Cell death or cell survival?
    • Mazure NM and Pouysségur J: Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol 22: 177-180, 2010.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 177-180
    • Mazure, N.M.1    Pouysségur, J.2
  • 40
    • 33847400593 scopus 로고    scopus 로고
    • Metabolic catastrophe as a means to cancer cell death
    • DOI 10.1242/jcs.03349
    • Jin S, DiPaola RS, Mathew R and White E: Metabolic catastrophe as a means to cancer cell death. J Cell Sci 120: 379-383, 2007. (Pubitemid 46332501)
    • (2007) Journal of Cell Science , vol.120 , Issue.3 , pp. 379-383
    • Jin, S.1    DiPaola, R.S.2    Mathew, R.3    White, E.4
  • 41
    • 48249108314 scopus 로고    scopus 로고
    • Tumor suppression by autophagy through the management of metabolic stress
    • Jin S and White E: Tumor suppression by autophagy through the management of metabolic stress. Autophagy 4: 563-566, 2008.
    • (2008) Autophagy , vol.4 , pp. 563-566
    • Jin, S.1    White, E.2
  • 43
    • 84861684979 scopus 로고    scopus 로고
    • Autophagy is a survival force via suppression of necrotic cell death
    • Shen H-M and Codogno P: Autophagy is a survival force via suppression of necrotic cell death. Exp Cell Res 318: 1304-1308, 2012.
    • (2012) Exp Cell Res , vol.318 , pp. 1304-1308
    • Shen, H.-M.1    Codogno, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.