메뉴 건너뛰기




Volumn 41, Issue 5, 2013, Pages 952-957

Decreased CYP3A expression and activity in guinea pig models of diet-induced metabolic syndrome: Is fatty liver infiltration involved?

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A; DOMPERIDONE; DRUG METABOLITE; FATTY ACID; MESSENGER RNA; TRIACYLGLYCEROL;

EID: 84876765619     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.050641     Document Type: Article
Times cited : (24)

References (27)
  • 2
    • 33144485957 scopus 로고    scopus 로고
    • Regulation of drug-metabolizing enzymes and transporters in inflammation
    • Aitken AE, Richardson TA, and Morgan ET (2006) Regulation of drug-metabolizing enzymes and transporters in inflammation. Annu Rev Pharmacol Toxicol 46:123-149.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 123-149
    • Aitken, A.E.1    Richardson, T.A.2    Morgan, E.T.3
  • 3
    • 0032211575 scopus 로고    scopus 로고
    • Regional differences in the delayed rectifier current (IKr and IKs) contribute to the differences in action potential duration in basal left ventricular myocytes in guinea-pig
    • Bryant SM, Wan X, Shipsey SJ, and Hart G (1998) Regional differences in the delayed rectifier current (IKr and IKs) contribute to the differences in action potential duration in basal left ventricular myocytes in guinea-pig. Cardiovasc Res 40:322-331.
    • (1998) Cardiovasc Res , vol.40 , pp. 322-331
    • Bryant, S.M.1    Wan, X.2    Shipsey, S.J.3    Hart, G.4
  • 4
    • 84857048311 scopus 로고    scopus 로고
    • Metabolic syndrome potentiates the cardiac action potential-prolonging action of drugs: A pOSSIBLE 'anti-proarrhythmic' role for amlodipine
    • Caillier B, Pilote S, Patoine D, Levac X, Couture C, Daleau P, Simard C, and Drolet B (2012) Metabolic syndrome potentiates the cardiac action potential-prolonging action of drugs: A possible 'anti-proarrhythmic' role for amlodipine. Pharmacol Res 65:320-327.
    • (2012) Pharmacol Res , vol.65 , pp. 320-327
    • Caillier, B.1    Pilote, S.2    Patoine, D.3    Levac, X.4    Couture, C.5    Daleau, P.6    Simard, C.7    Drolet, B.8
  • 5
    • 0029092424 scopus 로고
    • Carbamazepine pharmacokinetics in obese and lean subjects
    • Caraco Y, Zylber-Katz E, Berry EM, and Levy M (1995) Carbamazepine pharmacokinetics in obese and lean subjects. Ann Pharmacother 29:843-847.
    • (1995) Ann Pharmacother , vol.29 , pp. 843-847
    • Caraco, Y.1    Zylber-Katz, E.2    Berry, E.M.3    Levy, M.4
  • 6
    • 0036890399 scopus 로고    scopus 로고
    • The cytochrome P450 superfamily: Biochemistry, evolution and drug metabolism in humans
    • Danielson PB (2002) The cytochrome P450 superfamily: Biochemistry, evolution and drug metabolism in humans. Curr Drug Metab 3:561-597.
    • (2002) Curr Drug Metab , vol.3 , pp. 561-597
    • Danielson, P.B.1
  • 8
    • 79958811096 scopus 로고    scopus 로고
    • Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus
    • Dostalek M, Court MH, Yan B, and Akhlaghi F (2011) Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus. Br J Pharmacol 163:937-947.
    • (2011) Br J Pharmacol , vol.163 , pp. 937-947
    • Dostalek, M.1    Court, M.H.2    Yan, B.3    Akhlaghi, F.4
  • 9
    • 80054924410 scopus 로고    scopus 로고
    • A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients
    • Elens L, Bouamar R, Hesselink DA, Haufroid V, van der Heiden IP, van Gelder T, and van Schaik RH (2011) A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients. Clin Chem 57:1574-1583.
    • (2011) Clin Chem , vol.57 , pp. 1574-1583
    • Elens, L.1    Bouamar, R.2    Hesselink, D.A.3    Haufroid, V.4    Van Der Heiden, I.P.5    Van Gelder, T.6    Van Schaik, R.H.7
  • 12
    • 0024362052 scopus 로고
    • Haloperidol reductase in human and guinea pig livers
    • Inaba T and Kovacs J (1989) Haloperidol reductase in human and guinea pig livers. Drug Metab Dispos 17:330-333.
    • (1989) Drug Metab Dispos , vol.17 , pp. 330-333
    • Inaba, T.1    Kovacs, J.2
  • 13
    • 0037131879 scopus 로고    scopus 로고
    • Genetic contribution to variable human CYP3A-mediated metabolism
    • Lamba JK, Lin YS, Schuetz EG, and Thummel KE (2002) Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev 54:1271-1294.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1271-1294
    • Lamba, J.K.1    Lin, Y.S.2    Schuetz, E.G.3    Thummel, K.E.4
  • 14
    • 0032030819 scopus 로고    scopus 로고
    • Reduction in hepatic cytochrome P-450 is correlated to the degree of liver fat content in animal models of steatosis in the absence of inflammation
    • Leclercq I, Horsmans Y, Desager JP, Delzenne N, and Geubel AP (1998) Reduction in hepatic cytochrome P-450 is correlated to the degree of liver fat content in animal models of steatosis in the absence of inflammation. J Hepatol 28:410-416.
    • (1998) J Hepatol , vol.28 , pp. 410-416
    • Leclercq, I.1    Horsmans, Y.2    Desager, J.P.3    Delzenne, N.4    Geubel, A.P.5
  • 15
    • 0036176194 scopus 로고    scopus 로고
    • Update on nonalcoholic fatty liver disease
    • McCullough AJ (2002) Update on nonalcoholic fatty liver disease. J Clin Gastroenterol 34: 255-262.
    • (2002) J Clin Gastroenterol , vol.34 , pp. 255-262
    • McCullough, A.J.1
  • 18
    • 0037126526 scopus 로고    scopus 로고
    • Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report
    • NCEPNational Cholesterol Education Program]
    • NCEPNational Cholesterol Education Program] (2002) Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 106:3143-3421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 21
    • 11244267290 scopus 로고    scopus 로고
    • Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone
    • Simard C, Michaud V, Gibbs B, Massé R, Lessard E, and Turgeon J (2004) Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone. Xenobiotica 34: 1013-1023.
    • (2004) Xenobiotica , vol.34 , pp. 1013-1023
    • Simard, C.1    Michaud, V.2    Gibbs, B.3    Massé, R.4    Lessard, E.5    Turgeon, J.6
  • 23
    • 84861738395 scopus 로고    scopus 로고
    • Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
    • Takahashi Y, Soejima Y, and Fukusato T (2012) Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 18:2300-2308.
    • (2012) World J Gastroenterol , vol.18 , pp. 2300-2308
    • Takahashi, Y.1    Soejima, Y.2    Fukusato, T.3
  • 24
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Vandesompele J, De PK, Pattyn F, Poppe B, Van RN, De PA, and Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De, P.K.2    Pattyn, F.3    Poppe, B.4    Van, R.N.5    De, P.A.6    Speleman, F.7
  • 25
    • 1642387019 scopus 로고    scopus 로고
    • Guinea pigs as models to study the hypocholesterolemic effects of drugs
    • West KL and Fernandez ML (2004) Guinea pigs as models to study the hypocholesterolemic effects of drugs. Cardiovasc Drug Rev 22:55-70.
    • (2004) Cardiovasc Drug Rev , vol.22 , pp. 55-70
    • West, K.L.1    Fernandez, M.L.2
  • 26
    • 82955247909 scopus 로고    scopus 로고
    • IDF diabetes atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
    • Whiting DR, Guariguata L, Weil C, and Shaw J (2011) IDF diabetes atlas: Global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract 94:311-321.
    • (2011) Diabetes Res Clin Pract , vol.94 , pp. 311-321
    • Whiting, D.R.1    Guariguata, L.2    Weil, C.3    Shaw, J.4
  • 27
    • 33745427575 scopus 로고    scopus 로고
    • Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet
    • Yoshinari K, Takagi S, Yoshimasa T, Sugatani J, and Miwa M (2006) Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet. Pharm Res 23:1188-1200.
    • (2006) Pharm Res , vol.23 , pp. 1188-1200
    • Yoshinari, K.1    Takagi, S.2    Yoshimasa, T.3    Sugatani, J.4    Miwa, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.