Intrathecal application of short interfering RNA knocks down c-jun expression and augments spinal motoneuron death after root avulsion in adult rats

Neuroscience

Volumn 241, Issue , 2013, Pages 268-279

  Cheng, X ^a   Fu, R ^a   Gao, M ^b   Liu, S ^a   Li, Y Q ^a   Song, F H ^a   Bruce, I C ^e   Zhou, L H ^a   Wu, W ^b,c,d  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d JINAN UNIVERSITY   (China)

^e ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

C jun; Gene silencing; Motoneurons; Regeneration; RNA interference; Root avulsion

Indexed keywords

MESSENGER RNA; PROTEIN C JUN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVULSION INJURY; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; GENE FUNCTION; IN VITRO STUDY; IN VIVO STUDY; MALE; NERVE CELL NECROSIS; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD INJURY; SPINAL CORD MOTONEURON; SPINAL ROOT;

AGING; ANIMALS; BLOTTING, WESTERN; CELL DEATH; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKDOWN TECHNIQUES; GENES, JUN; IMMUNOHISTOCHEMISTRY; INJECTIONS, SPINAL; MALE; MOTOR NEURONS; PC12 CELLS; RADICULOPATHY; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SPINAL CORD; TRANSFECTION;

EID: 84876703576     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.03.006     Document Type: Article

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