Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris

Journal of the American College of Cardiology

Volumn 58, Issue 8, 2011, Pages 820-828

  Rajendra, Narasimharajapura S ^a   Ireland, Sheila ^a   George, Jacob ^a   Belch, Jill J F ^a   Lang, Chim C ^a   Struthers, Allan D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

allopurinol and endothelial dysfunction; coronary artery disease; vascular oxidative stress; xanthine oxidase

Indexed keywords

ACETYLCHOLINE; ACETYLSALICYLIC ACID; ALLOPURINOL; ANGIOTENSIN RECEPTOR ANTAGONIST; ASCORBIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRATE; PLACEBO; RAMIPRIL; SIMVASTATIN; THIAZIDE DIURETIC AGENT;

AGED; ANGINA PECTORIS; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CROSSOVER PROCEDURE; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG MEGADOSE; FEMALE; FOREARM; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PULSE WAVE; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; VASCULAR ENDOTHELIUM; VASCULAR TISSUE; VEIN OCCLUSION PLETHYSMOGRAPHY;

AGED; ALLOPURINOL; ANGINA PECTORIS; ANTIOXIDANTS; ASCORBIC ACID; BLOOD FLOW VELOCITY; BRACHIAL ARTERY; CORONARY ARTERY DISEASE; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; F2-ISOPROSTANES; FEMALE; HUMANS; LIPOPROTEINS, LDL; MALE; NATRIURETIC PEPTIDE, BRAIN; OXIDATIVE STRESS; PLETHYSMOGRAPHY; REGIONAL BLOOD FLOW;

EID: 80051616824     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2010.12.052     Document Type: Article

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