High-level expression and immunogenicity of a porcine circovirus type 2 capsid protein through codon optimization in Pichia pastoris

Applied Microbiology and Biotechnology

Volumn 97, Issue 7, 2013, Pages 2867-2875

  Tu, Yabin ^a   Wang, Yanqun ^a   Wang, Gang ^a   Wu, Jianan ^a   Liu, Yonggang ^a   Wang, Shujie ^a   Jiang, Chenggang ^a   Cai, Xuehui ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Capsid protein; Expression; Immunogenicity; Pichia pastoris; Porcine circovirus type 2

Indexed keywords

CAPSID PROTEINS; EXPRESSION; IMMUNOGENICITY; PICHIA PASTORIS; PORCINE CIRCOVIRUS TYPE 2;

AMINO ACIDS; GENE ENCODING; OPTIMIZATION; POLYMERASE CHAIN REACTION; PROTEINS; VACCINES; YEAST;

GENE EXPRESSION;

ALCOHOL OXIDASE; CAPSID PROTEIN; OPTIMIZED CAPSID PROTEIN; PORCINE CIRCOVIRUS TYPE 2 CAPSID PROTEIN; SIGNAL PEPTIDE; SUBUNIT VACCINE; UNCLASSIFIED DRUG; WILD TYPE CAPSID PROTEIN;

AMINO ACID; ANTIGEN; DNA; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNE SYSTEM; OPTIMIZATION; PLASMID; POLYMERASE CHAIN REACTION; PROTEIN; VACCINATION; VIRUS; YEAST;

AMINO ACID SEQUENCE; ARTICLE; CIRCOVIRUS; CODON; CONTROLLED STUDY; ELECTROPORATION; GENE INSERTION; IMMUNOGENICITY; LYMPH NODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PICHIA PASTORIS; POLYMERASE CHAIN REACTION; POSTWEANING MULTISYSTEMIC WASTING SYNDROME; PROCESS OPTIMIZATION; RECOMBINANT PLASMID; SACCHAROMYCES CEREVISIAE; SWINE; VIRUS EXPRESSION; WILD TYPE;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CAPSID PROTEINS; CIRCOVIRUS; CODON; GENE EXPRESSION; GENETIC VECTORS; MOLECULAR SEQUENCE DATA; PICHIA; PLASMIDS; PROMOTER REGIONS, GENETIC; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, DNA; SWINE; VIRAL VACCINES;

MIRIDAE; PICHIA PASTORIS; PORCINE CIRCOVIRUS 2; SACCHAROMYCES CEREVISIAE; SUIDAE;

EID: 84876684922     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4540-z     Document Type: Article

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