KRAS and BRAF mutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue

International Journal of Cancer

Volumn 133, Issue 1, 2013, Pages 130-141

  Mostert, Bianca ^a   Jiang, Yuqiu ^b,d   Sieuwerts, Anieta M ^a   Wang, Haiying ^b,d   Bolt De Vries, Joan ^a   Biermann, Katharina ^a   Kraan, Jaco ^a   Lalmahomed, Zarina ^a   Van Galen, Anne ^a   De Weerd, Vanja ^a   Van Der Spoel, Petra ^a   Ramírez Moreno, Raquel ^c   Verhoef, Cornelis ^a   Ijzermans, Jan N M ^a   Wang, Yixin ^b,d   Gratama, Jan Willem ^a   Foekens, John A ^a   Sleijfer, Stefan ^a   Martens, John W M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Veridex LLC   (United States)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^d PFIZER INC   (United States)

Author keywords

BRAF; circulating tumor cells; COLD PCR; colorectal cancer; KRAS

Indexed keywords

ADULT; AGED; AMINO ACID SUBSTITUTION; ANALYTIC METHOD; ARTICLE; BRAF GENE; CELL ISOLATION; CIRCULATING TUMOR CELL; CO AMPLIFICATION AT LOWER DENATURATION TEMPERATURE POLYMERASE CHAIN REACTION; COLORECTAL CANCER; CONTROLLED STUDY; DNA DETERMINATION; DNA SEQUENCE; FEASIBILITY STUDY; FEMALE; GENE IDENTIFICATION; GENETIC CORRELATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; KRAS GENE; LIVER METASTASIS; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; METASTASIS; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NESTED ALLELE SPECIFIC BLOCKER POLYMERASE CHAIN REACTION; PATIENT SELECTION; POLYMERASE CHAIN REACTION; PRIMARY TUMOR; PRIORITY JOURNAL; QUALITATIVE RESEARCH; QUANTITATIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; COLORECTAL NEOPLASMS; DNA, NEOPLASM; FEMALE; HCT116 CELLS; HUMANS; LIVER NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MUTATION; NEOPLASM STAGING; NEOPLASTIC CELLS, CIRCULATING; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; RNA, MESSENGER; RNA, NEOPLASM;

EID: 84876674310     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27987     Document Type: Article

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