The metallohormone cadmium modulates AhR-associated gene expression in the small intestine of rats similar to ethinyl-estradiol

Archives of Toxicology

Volumn 87, Issue 4, 2013, Pages 633-643

  Kluxen, Felix M ^a,b   Diel, Patrick ^a   Höfer, Nicola ^a,b   Becker, Eugenia ^a   Degen, Gisela H ^b  

^a GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^b TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Aryl hydrocarbon receptor; Cadmium; Endocrine disruption; Endocrine modulation; Estrogens

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CADMIUM; CADMIUM CHLORIDE; CYTOCHROME P450 1A1; ESTROGEN RECEPTOR BETA; ETHINYLESTRADIOL; GLUTATHIONE TRANSFERASE A2; MESSENGER RNA; METALLOTHIONEIN 1A; METALLOTHIONEIN I; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE QUINONE 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN CACO 2; CELL STRAIN HT29; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SMALL INTESTINE; UTERUS;

ANIMALS; CACO-2 CELLS; CADMIUM CHLORIDE; CELL SURVIVAL; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; ESTRADIOL; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; ETHINYL ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; INTESTINE, SMALL; ISOENZYMES; METALLOTHIONEIN; NAD(P)H DEHYDROGENASE (QUINONE); ORGAN SIZE; OVARIECTOMY; RATS; RATS, WISTAR; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; UTERUS;

RATTUS; RATTUS NORVEGICUS;

EID: 84876666579     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0971-7     Document Type: Article

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