메뉴 건너뛰기




Volumn 62, Issue 5, 2013, Pages 1537-1546

Fyn deficiency promotes a preferential increase in subcutaneous adipose tissue mass and decreased visceral adipose tissue inflammation

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE; INSULIN; PROTEIN KINASE FYN;

EID: 84876581721     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0920     Document Type: Article
Times cited : (28)

References (46)
  • 1
  • 2
    • 37549022688 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • DOI 10.1016/j.febslet.2007.11.057, PII S0014579307012082
    • de Luca C, Olefsky JM. Inflammation and insulin resistance. FEBS Lett 2008;582:97-105 (Pubitemid 50010731)
    • (2008) FEBS Letters , vol.582 , Issue.1 , pp. 97-105
    • De Luca, C.1    Olefsky, J.M.2
  • 3
    • 33747356154 scopus 로고    scopus 로고
    • Adipose tissue: From lipid storage compartment to endocrine organ
    • DOI 10.2337/db06-0263
    • Scherer PE. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 2006;55:1537-1545 (Pubitemid 44324105)
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1537-1545
    • Scherer, P.E.1
  • 5
    • 0034179765 scopus 로고    scopus 로고
    • Visceral obesity and metabolic syndrome
    • Bosello O, Zamboni M. Visceral obesity and metabolic syndrome. Obes Rev 2000;1:47-56
    • (2000) Obes Rev , vol.1 , pp. 47-56
    • Bosello, O.1    Zamboni, M.2
  • 6
    • 18144408371 scopus 로고    scopus 로고
    • Adipose tissue, adipokines, and inflammation
    • quiz 920
    • Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 2005;115:911-919; quiz 920
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 911-919
    • Fantuzzi, G.1
  • 9
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • DOI 10.1172/JCI29881
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007;117:175-184 (Pubitemid 46048464)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.1 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 10
    • 33847073149 scopus 로고    scopus 로고
    • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
    • Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes 2007;56:16-23
    • (2007) Diabetes , vol.56 , pp. 16-23
    • Lumeng, C.N.1    Deyoung, S.M.2    Bodzin, J.L.3    Saltiel, A.R.4
  • 11
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer M, Herrero L, Cipolletta D, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009;15:930-939
    • (2009) Nat Med , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3
  • 12
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009;15:914-920
    • (2009) Nat Med , vol.15 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 13
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • Lee JY, Sohn KH, Rhee SH, Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 2001;276:16683-16689
    • (2001) J Biol Chem , vol.276 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 16
    • 77957054466 scopus 로고    scopus 로고
    • The mammalian target of rapamycin: Linking T cell differentiation, function, and metabolism
    • Powell JD, Delgoffe GM. The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism. Immunity 2010;33:301-311
    • (2010) Immunity , vol.33 , pp. 301-311
    • Powell, J.D.1    Delgoffe, G.M.2
  • 17
    • 80054726323 scopus 로고    scopus 로고
    • The liver kinase B1 is a central regulator of T cell development, activation, and metabolism
    • MacIver NJ, Blagih J, Saucillo DC, et al. The liver kinase B1 is a central regulator of T cell development, activation, and metabolism. J Immunol 2011;187:4187-4198
    • (2011) J Immunol , vol.187 , pp. 4187-4198
    • MacIver, N.J.1    Blagih, J.2    Saucillo, D.C.3
  • 19
    • 0036347746 scopus 로고    scopus 로고
    • Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
    • Parravicini V, Gadina M, Kovarova M, et al. Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation. Nat Immunol 2002;3:741-748
    • (2002) Nat Immunol , vol.3 , pp. 741-748
    • Parravicini, V.1    Gadina, M.2    Kovarova, M.3
  • 20
    • 0032723181 scopus 로고    scopus 로고
    • The Src family tyrosine kinase Fyn regulates natural killer T cell development
    • Gadue P, Morton N, Stein PL. The Src family tyrosine kinase Fyn regulates natural killer T cell development. J Exp Med 1999;190:1189-1196
    • (1999) J Exp Med , vol.190 , pp. 1189-1196
    • Gadue, P.1    Morton, N.2    Stein, P.L.3
  • 21
    • 7944231534 scopus 로고    scopus 로고
    • Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation
    • DOI 10.1038/sj.onc.1208074
    • Palacios EH, Weiss A. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene 2004;23:7990-8000 (Pubitemid 39468856)
    • (2004) Oncogene , vol.23 , Issue.48 REV. ISS. 7 , pp. 7990-8000
    • Palacios, E.H.1    Weiss, A.2
  • 22
    • 61849128182 scopus 로고    scopus 로고
    • T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
    • Salmond RJ, Filby A, Qureshi I, Caserta S, Zamoyska R. T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance. Immunol Rev 2009;228:9-22
    • (2009) Immunol Rev , vol.228 , pp. 9-22
    • Salmond, R.J.1    Filby, A.2    Qureshi, I.3    Caserta, S.4    Zamoyska, R.5
  • 23
    • 0030744872 scopus 로고    scopus 로고
    • Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells
    • DOI 10.1074/jbc.272.33.20706
    • Mastick CC, Saltiel AR. Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells. J Biol Chem 1997;272:20706-20714 (Pubitemid 27355635)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.33 , pp. 20706-20714
    • Mastick, C.C.1    Saltiel, A.R.2
  • 24
    • 0035903208 scopus 로고    scopus 로고
    • Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction
    • Liang X, Nazarian A, Erdjument-Bromage H, Bornmann W, Tempst P, Resh MD. Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. J Biol Chem 2001;276:30987-30994
    • (2001) J Biol Chem , vol.276 , pp. 30987-30994
    • Liang, X.1    Nazarian, A.2    Erdjument-Bromage, H.3    Bornmann, W.4    Tempst, P.5    Resh, M.D.6
  • 25
    • 0031594145 scopus 로고    scopus 로고
    • A novel, multifunctional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes
    • Ribon V, Printen JA, Hoffman NG, Kay BK, Saltiel AR. A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. Mol Cell Biol 1998;18:872-879 (Pubitemid 28063420)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.2 , pp. 872-879
    • Ribon, V.1    Printen, J.A.2    Hoffman, N.G.3    Kay, B.K.4    Saltiel, A.R.5
  • 26
    • 15844409347 scopus 로고    scopus 로고
    • The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation
    • DOI 10.1074/jbc.271.18.10583
    • Sun XJ, Pons S, Asano T, Myers MG Jr, Glasheen E, White MF. The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation. J Biol Chem 1996;271:10583-10587 (Pubitemid 26149894)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.18 , pp. 10583-10587
    • Sun, X.J.1    Pons, S.2    Asano, T.3    Myers Jr., M.G.4    Glasheen, E.5    White, M.F.6
  • 27
    • 0036470213 scopus 로고    scopus 로고
    • Insulin signaling pathways in time and space
    • Saltiel AR, Pessin JE. Insulin signaling pathways in time and space. Trends Cell Biol 2002;12:65 -71
    • (2002) Trends Cell Biol , vol.12 , pp. 65-71
    • Saltiel, A.R.1    Pessin, J.E.2
  • 28
    • 34247566256 scopus 로고    scopus 로고
    • Integrative Metabolic Regulation of Peripheral Tissue Fatty Acid Oxidation by the Src Kinase Family Member Fyn
    • DOI 10.1016/j.cmet.2007.04.005, PII S1550413107001003
    • Bastie CC, Zong H, Xu J, et al. Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn. Cell Metab 2007;5:371-381 (Pubitemid 46679518)
    • (2007) Cell Metabolism , vol.5 , Issue.5 , pp. 371-381
    • Bastie, C.C.1    Zong, H.2    Xu, J.3    Busa, B.4    Judex, S.5    Kurland, I.J.6    Pessin, J.E.7
  • 29
    • 75149117805 scopus 로고    scopus 로고
    • Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1
    • Yamada E, Pessin JE, Kurland IJ, Schwartz GJ, Bastie CC. Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1. Cell Metab 2010;11:113-124
    • (2010) Cell Metab , vol.11 , pp. 113-124
    • Yamada, E.1    Pessin, J.E.2    Kurland, I.J.3    Schwartz, G.J.4    Bastie, C.C.5
  • 30
    • 84861706956 scopus 로고    scopus 로고
    • Mouse skeletal muscle fiber-type-specific macroautophagy and muscle wasting are regulated by a Fyn/STAT3/Vps34 signaling pathway
    • Yamada E, Bastie CC, Koga H, Wang Y, Cuervo AM, Pessin JE. Mouse skeletal muscle fiber-type-specific macroautophagy and muscle wasting are regulated by a Fyn/STAT3/Vps34 signaling pathway. Cell Rep 2012;1:557-569
    • (2012) Cell Rep , vol.1 , pp. 557-569
    • Yamada, E.1    Bastie, C.C.2    Koga, H.3    Wang, Y.4    Cuervo, A.M.5    Pessin, J.E.6
  • 31
    • 84857350273 scopus 로고    scopus 로고
    • Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance
    • Zong H, Armoni M, Harel C, Karnieli E, Pessin JE. Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance. Am J Physiol Endocrinol Metab 2012;302:E532-E539
    • (2012) Am J Physiol Endocrinol Metab , vol.302
    • Zong, H.1    Armoni, M.2    Harel, C.3    Karnieli, E.4    Pessin, J.E.5
  • 34
    • 0028243540 scopus 로고
    • Role of tyrosine kinases in lymphocyte activation
    • DOI 10.1016/0952-7915(94)90115-5
    • Sefton BM, Taddie JA. Role of tyrosine kinases in lymphocyte activation. Curr Opin Immunol 1994;6:372-379 (Pubitemid 24188485)
    • (1994) Current Opinion in Immunology , vol.6 , Issue.3 , pp. 372-379
    • Sefton, B.M.1
  • 35
    • 0032763207 scopus 로고    scopus 로고
    • Transgenic mice lacking white fat: Models for understanding human lipoatrophic diabetes
    • Reitman ML, Mason MM, Moitra J, et al. Transgenic mice lacking white fat: models for understanding human lipoatrophic diabetes. Ann N Y Acad Sci 1999;892:289-296
    • (1999) Ann N Y Acad Sci , vol.892 , pp. 289-296
    • Reitman, M.L.1    Mason, M.M.2    Moitra, J.3
  • 37
    • 54749114466 scopus 로고    scopus 로고
    • It 's not how fat you are, it's what you do with it that counts
    • Virtue S, Vidal-Puig A. It 's not how fat you are, it's what you do with it that counts. PLoS Biol 2008;6:e237
    • (2008) PLoS Biol , vol.6
    • Virtue, S.1    Vidal-Puig, A.2
  • 38
    • 55849106577 scopus 로고    scopus 로고
    • Role of body fat distribution and the metabolic complications of obesity
    • Jensen MD. Role of body fat distribution and the metabolic complications of obesity. J Clin Endocrinol Metab 2008;93(Suppl. 1):S57-S63
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.SUPPL. 1
    • Jensen, M.D.1
  • 39
    • 42649144463 scopus 로고    scopus 로고
    • Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism
    • DOI 10.1016/j.cmet.2008.04.004, PII S1550413108001149
    • Tran TT, Yamamoto Y, Gesta S, Kahn CR. Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab 2008;7:410-420 (Pubitemid 351598027)
    • (2008) Cell Metabolism , vol.7 , Issue.5 , pp. 410-420
    • Tran, T.T.1    Yamamoto, Y.2    Gesta, S.3    Kahn, C.R.4
  • 43
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91 (Pubitemid 23036092)
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 44
    • 47149096915 scopus 로고    scopus 로고
    • Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity
    • DOI 10.2174/138161208784246153
    • Heilbronn LK, Campbell LV. Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity. Curr Pharm Des 2008;14:1225-1230 (Pubitemid 351997835)
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.12 , pp. 1225-1230
    • Heilbronn, L.K.1    Campbell, L.V.2
  • 45
    • 0033817250 scopus 로고    scopus 로고
    • Effects of dietary n-3 fatty acids on T cell activation and T cell receptor-mediated signaling in a murine model
    • McMurray DN, Jolly CA, Chapkin RS. Effects of dietary n-3 fatty acids on T cell activation and T cell receptor-mediated signaling in a murine model. J Infect Dis 2000;182(Suppl. 1):S103-S107
    • (2000) J Infect Dis , vol.182 , Issue.SUPPL. 1
    • McMurray, D.N.1    Jolly, C.A.2    Chapkin, R.S.3
  • 46
    • 84856533216 scopus 로고    scopus 로고
    • Increased macrophage migration into adipose tissue in obese mice
    • Oh DY, Morinaga H, Talukdar S, Bae EJ, Olefsky JM. Increased macrophage migration into adipose tissue in obese mice. Diabetes 2012;61:346-354
    • (2012) Diabetes , vol.61 , pp. 346-354
    • Oh, D.Y.1    Morinaga, H.2    Talukdar, S.3    Bae, E.J.4    Olefsky, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.