메뉴 건너뛰기




Volumn 9, Issue 1, 2013, Pages 22-28

Non-viral gene-activated matrices: Next generation constructs for bone repair

Author keywords

Bone repair; Gene activated matrices; Mesenchymal stem cells; Non viral gene delivery vectors; Orthopaedic gene therapy; Regenerative medicine; Scaffolds; Tissue engineering

Indexed keywords

BONE MORPHOGENETIC PROTEIN 6; COLLAGEN; EPHRIN B2; EPHRIN RECEPTOR B4; PLASMID DNA; POLYETHYLENEIMINE; VIRUS VECTOR; TISSUE SCAFFOLD;

EID: 84876566511     PISSN: 15476278     EISSN: 15558592     Source Type: Journal    
DOI: 10.4161/org.24329     Document Type: Review
Times cited : (37)

References (65)
  • 1
    • 29544449422 scopus 로고    scopus 로고
    • To engineer is to create: The link between engineering and regeneration
    • DOI 10.1016/j.tibtech.2005.10.006, PII S0167779905002805
    • Williams DF. To engineer is to create: the link between engineering and regeneration. Trends Biotechnol 2006; 24:4-8; PMID:16289395; http://dx.doi.org/10.1016/j.tibtech.2005.10.006. (Pubitemid 43017744)
    • (2006) Trends in Biotechnology , vol.24 , Issue.1 , pp. 4-8
    • Williams, D.F.1
  • 3
    • 78651341992 scopus 로고    scopus 로고
    • Template for skin regeneration
    • PMID:21200274
    • Yannas IV, Orgill DP, Burke JF. Template for skin regeneration. Plast Reconstr Surg 2011; 127(Suppl 1):60S-70S; PMID:21200274; http://dx.doi.org/10. 1097/PRS.0b013e318200a44d.
    • (2011) Plast Reconstr Surg , vol.127 , Issue.SUPPL. 1
    • Yannas, I.V.1    Orgill, D.P.2    Burke, J.F.3
  • 4
    • 79953283872 scopus 로고    scopus 로고
    • Tissue-engineered autologous urethras for patients who need reconstruction: An observational study
    • PMID:21388673
    • Raya-Rivera A, Esquiliano DR, Yoo JJ, Lopez-Bayghen E, Soker S, Atala A. Tissue-engineered autologous urethras for patients who need reconstruction: an observational study. Lancet 2011; 377:1175-82; PMID:21388673; http://dx.doi.org/10.1016/S0140-6736(10)62354-9.
    • (2011) Lancet , vol.377 , pp. 1175-1182
    • Raya-Rivera, A.1    Esquiliano, D.R.2    Yoo, J.J.3    Lopez-Bayghen, E.4    Soker, S.5    Atala, A.6
  • 5
    • 79957624834 scopus 로고    scopus 로고
    • Esophageal preservation in five male patients after endoscopic inner-layer circumferential resection in the setting of superficial cancer: A regenerative medicine approach with a biologic scaffold
    • PMID:21306292
    • Badylak SF, Hoppo T, Nieponice A, Gilbert T W, Davison JM, Jobe BA. Esophageal preservation in five male patients after endoscopic inner-layer circumferential resection in the setting of superficial cancer: a regenerative medicine approach with a biologic scaffold. Tissue Eng Part A 2011; 17:1643-50; PMID:21306292; http://dx.doi.org/10.1089/ten.tea.2010.0739.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1643-1650
    • Badylak, S.F.1    Hoppo, T.2    Nieponice, A.3    Gilbert, T.W.4    Davison, J.M.5    Jobe, B.A.6
  • 6
    • 57349176894 scopus 로고    scopus 로고
    • Clinical transplantation of a tissue-engineered airway
    • PMID:19022496
    • Macchiarini P, Jungebluth P, Go T, Asnaghi MA, Rees LE, Cogan TA, et al. Clinical transplantation of a tissue-engineered airway. Lancet 2008; 372:2023-30; PMID:19022496; http://dx.doi.org/10.1016/S0140-6736(08)61598-6.
    • (2008) Lancet , vol.372 , pp. 2023-2030
    • MacChiarini, P.1    Jungebluth, P.2    Go, T.3    Asnaghi, M.A.4    Rees, L.E.5    Cogan, T.A.6
  • 7
    • 84858860614 scopus 로고    scopus 로고
    • The concept of in vivo airway tissue engineering
    • PMID:22440048
    • Jungebluth P, Bader A, Baiguera S, Möller S, Jaus M, Lim ML, et al. The concept of in vivo airway tissue engineering. Biomaterials 2012; 33:4319-26; PMID:22440048; http://dx.doi.org/10.1016/j.bio-materials.2012.03.016.
    • (2012) Biomaterials , vol.33 , pp. 4319-4326
    • Jungebluth, P.1    Bader, A.2    Baiguera, S.3    Möller, S.4    Jaus, M.5    Lim, M.L.6
  • 8
    • 33751241416 scopus 로고    scopus 로고
    • Scaffolds for stem cells
    • DOI 10.1016/S1369-7021(06)71740-0, PII S1369702106717400
    • Evans ND, Gentleman E, Polak JM. Scaffolds for stem cells. Mater Today 2006; 9:26-33; http://dx.doi.org/10.1016/S1369-7021(06)71740-0. (Pubitemid 44781424)
    • (2006) Materials Today , vol.9 , Issue.12 , pp. 26-33
    • Evans, N.D.1    Gentleman, E.2    Polak, J.M.3
  • 9
    • 77953467681 scopus 로고    scopus 로고
    • A novel collagen scaffold supports human osteogenesis-appli-cations for bone tissue engineering
    • PMID:20198386
    • Keogh MB, O' Brien FJ, Daly JS. A novel collagen scaffold supports human osteogenesis-appli-cations for bone tissue engineering. Cell Tissue Res 2010; 340:169-77; PMID:20198386; http://dx.doi.org/10.1007/s00441-010-0939-y.
    • (2010) Cell Tissue Res , vol.340 , pp. 169-177
    • Keogh, M.B.1    Brien F J, O.'.2    Daly, J.S.3
  • 10
    • 59349120485 scopus 로고    scopus 로고
    • The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen-GAG scaffolds for bone tissue engineering
    • PMID:19627824
    • Tierney CM, Haugh MG, Liedl J, Mulcahy F, Hayes B, O'Brien FJ. The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen-GAG scaffolds for bone tissue engineering. J Mech Behav Biomed Mater 2009; 2:202-9; PMID:19627824; http://dx.doi.org/10.1016/j.jmbbm.2008.08.007.
    • (2009) J Mech Behav Biomed Mater , vol.2 , pp. 202-209
    • Tierney, C.M.1    Haugh, M.G.2    Liedl, J.3    Mulcahy, F.4    Hayes, B.5    O'Brien, F.J.6
  • 11
    • 70449088920 scopus 로고    scopus 로고
    • The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering
    • PMID:19819008
    • Murphy CM, Haugh MG, O'Brien FJ. The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. Biomaterials 2010; 31:461-6; PMID:19819008; http://dx.doi.org/10.1016/j.biomaterials.2009.09.063.
    • (2010) Biomaterials , vol.31 , pp. 461-466
    • Murphy, C.M.1    Haugh, M.G.2    O'Brien, F.J.3
  • 12
    • 79952117387 scopus 로고    scopus 로고
    • Addition of hydroxyapatite improves stiffness, interconnectivity and osteogenic potential of a highly porous collagenbased scaffold for bone tissue regeneration
    • PMID:20922667
    • Gleeson JP, Plunkett NA, O'Brien FJ. Addition of hydroxyapatite improves stiffness, interconnectivity and osteogenic potential of a highly porous collagenbased scaffold for bone tissue regeneration. Eur Cell Mater 2010 ; 20:218-30; PMID:20922667.
    • (2010) Eur Cell Mater , vol.20 , pp. 218-230
    • Gleeson, J.P.1    Plunkett, N.A.2    O'Brien, F.J.3
  • 13
    • 67749142428 scopus 로고    scopus 로고
    • Development of a biomimetic collagen-hydroxyapa-tite scaffold for bone tissue engineering using a SBF immersion technique
    • PMID:19180526
    • Al-Munajjed AA, Plunkett NA, Gleeson JP, Weber T, Jungreuthmayer C, Levingstone T, et al. Development of a biomimetic collagen-hydroxyapa-tite scaffold for bone tissue engineering using a SBF immersion technique. J Biomed Mater Res B Appl Biomater 2009; 90:584-91; PMID:19180526; http://dx.doi.org/10. 1002/jbm.b.31320.
    • (2009) J Biomed Mater Res B Appl Biomater , vol.90 , pp. 584-591
    • Al-Munajjed, A.A.1    Plunkett, N.A.2    Gleeson, J.P.3    Weber, T.4    Jungreuthmayer, C.5    Levingstone, T.6
  • 14
    • 78649874333 scopus 로고    scopus 로고
    • Development and characterisation of a collagen nano-hydroxyapatite composite scaffold for bone tissue engineering
    • PMID:20091099
    • Cunniffe GM, Dickson GR, Partap S, Stanton KT, O'Brien FJ. Development and characterisation of a collagen nano-hydroxyapatite composite scaffold for bone tissue engineering. J Mater Sci Mater Med 2010; 21:2293-8; PMID:20091099; http://dx.doi.org/10.1007/s10856-009-3964-1.
    • (2010) J Mater Sci Mater Med , vol.21 , pp. 2293-2298
    • Cunniffe, G.M.1    Dickson, G.R.2    Partap, S.3    Stanton, K.T.4    O'Brien, F.J.5
  • 15
    • 0242438580 scopus 로고    scopus 로고
    • Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds
    • DOI 10.1016/S0142-9612(03)00630-6
    • O'Brien FJ, Harley BA, Yannas IV, Gibson L. Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds. Biomaterials 2004; 25:1077-86; PMID:14615173; http://dx.doi.org/10.1016/S0142-9612(03)00630-6. (Pubitemid 37393297)
    • (2004) Biomaterials , vol.25 , Issue.6 , pp. 1077-1086
    • O'Brien, F.J.1    Harley, B.A.2    Yannas, I.V.3    Gibson, L.4
  • 16
    • 78449282244 scopus 로고    scopus 로고
    • The synthesis and characterization of nanophase hydroxyapatite using a novel dispersant-aided precipitation method
    • PMID:20878985
    • Cunniffe GM, O'Brien FJ, Partap S, Levingstone TJ, Stanton K T, Dickson GR. The synthesis and characterization of nanophase hydroxyapatite using a novel dispersant-aided precipitation method. J Biomed Mater Res A 2010; 95:1142-9; PMID:20878985; http://dx.doi.org/10.1002/jbm.a.32931.
    • (2010) J Biomed Mater Res A , vol.95 , pp. 1142-1149
    • Cunniffe, G.M.1    O'Brien, F.J.2    Partap, S.3    Levingstone, T.J.4    Stanton, K.T.5    Dickson, G.R.6
  • 17
    • 84856480411 scopus 로고    scopus 로고
    • Innovative collagen nano-hydroxyapatite scaffolds offer a highly efficient non-viral gene delivery platform for stem cellmediated bone formation
    • PMID:22213347
    • Curtin CM, Cunniffe GM, Lyons FG, Bessho K, Dickson GR, Duffy GP, et al. Innovative collagen nano-hydroxyapatite scaffolds offer a highly efficient non-viral gene delivery platform for stem cellmediated bone formation. Adv Mater 2012; 24:749-54; PMID:22213347; http://dx.doi.org/10.1002/adma.201103828.
    • (2012) Adv Mater , vol.24 , pp. 749-754
    • Curtin, C.M.1    Cunniffe, G.M.2    Lyons, F.G.3    Bessho, K.4    Dickson, G.R.5    Duffy, G.P.6
  • 18
    • 77957943567 scopus 로고    scopus 로고
    • The healing of bony defects by cell-free collagen-based scaffolds compared to stem cell-seeded tissue engineered constructs
    • PMID:20863559
    • Lyons FG, Al-Munajjed AA, Kieran SM, Toner ME, Murphy CM, Duffy GP, et al. The healing of bony defects by cell-free collagen-based scaffolds compared to stem cell-seeded tissue engineered constructs. Biomaterials 2010; 31:9232-43; PMID:20863559; http://dx.doi.org/10.1016/j.bio-materials.2010.08.056.
    • (2010) Biomaterials , vol.31 , pp. 9232-9243
    • Lyons, F.G.1    Al-Munajjed, A.A.2    Kieran, S.M.3    Toner, M.E.4    Murphy, C.M.5    Duffy, G.P.6
  • 19
    • 79951945999 scopus 로고    scopus 로고
    • Evaluation of early healing events around mesenchymal stem cell-seeded collagen-gly-cosaminoglycan scaffold. An experimental study in Wistar rats
    • PMID:20644972
    • Alhag M, Farrell E, Toner ME, Claffey N, Lee TC, O'Brien F. Evaluation of early healing events around mesenchymal stem cell-seeded collagen-gly- cosaminoglycan scaffold. An experimental study in Wistar rats. Oral Maxillofac Surg 2011; 15:31-9; PMID:20644972; http://dx.doi.org/10.1007/s10006-010-0241-x.
    • (2011) Oral Maxillofac Surg , vol.15 , pp. 31-39
    • Alhag, M.1    Farrell, E.2    Toner, M.E.3    Claffey, N.4    Lee, T.C.5    O'Brien, F.6
  • 20
    • 84857896599 scopus 로고    scopus 로고
    • Evaluation of the ability of colla-gen-glycosaminoglycan scaffolds with or without mesenchymal stem cells to heal bone defects in Wistar rats
    • PMID:21968608
    • Alhag M, Farrell E, Toner M, Lee TC, O'Brien FJ, Claffey N. Evaluation of the ability of colla-gen-glycosaminoglycan scaffolds with or without mesenchymal stem cells to heal bone defects in Wistar rats. Oral Maxillofac Surg 2012; 16:47-55; PMID:21968608; http://dx.doi.org/10.1007/s10006-011-0299-0.
    • (2012) Oral Maxillofac Surg , vol.16 , pp. 47-55
    • Alhag, M.1    Farrell, E.2    Toner, M.3    Lee, T.C.4    O'Brien, F.J.5    Claffey, N.6
  • 21
    • 68549087056 scopus 로고    scopus 로고
    • Viral vectors: From virology to transgene expression
    • PMID:18776913
    • Bouard D, Alazard-Dany D, Cosset FL. Viral vectors: from virology to transgene expression. Br J Pharmacol 2009; 157:153-65; PMID:18776913; http://dx.doi.org/10.1038/bjp.2008.349.
    • (2009) Br J Pharmacol , vol.157 , pp. 153-165
    • Bouard, D.1    Alazard-Dany, D.2    Cosset, F.L.3
  • 22
    • 79751506542 scopus 로고    scopus 로고
    • Gene therapy finds its niche
    • PMID:21301435
    • Sheridan C. Gene therapy finds its niche. Nat Biotechnol 2011; 29:121-8; PMID:21301435; http://d x.doi.org/10.1038/nbt.1769.
    • (2011) Nat Biotechnol , vol.29 , pp. 121-128
    • Sheridan, C.1
  • 23
    • 0037078985 scopus 로고    scopus 로고
    • A tragic setback
    • DOI 10.1038/420116a
    • Check E. A tragic setback. Nature 2002; 420:116-8; PMID:12432357; http://dx.doi.org/10.1038/420116a. (Pubitemid 35340095)
    • (2002) Nature , vol.420 , Issue.6912 , pp. 116-118
    • Check, E.1
  • 24
    • 0033579358 scopus 로고    scopus 로고
    • Gene therapy death prompts review of adenovirus vector
    • DOI 10.1126/science.286.5448.2244
    • Marshall E. Gene therapy death prompts review of adenovirus vector. Science 1999; 286:2244-5; PMID:10636774; http://dx.doi.org/10.1126/sci-ence.286. 5448.2244. (Pubitemid 30016842)
    • (1999) Science , vol.286 , Issue.5448 , pp. 2244-2245
    • Marshall, E.1
  • 25
    • 68549099700 scopus 로고    scopus 로고
    • Delivery of magic bullets: On the still rocky road to gene therapy
    • PMID:19459842
    • Takeda K. Delivery of magic bullets: on the still rocky road to gene therapy. Br J Pharmacol 2009; 157:151-2; PMID:19459842; http://dx.doi. o r g/10.1111/j.1476-53 81. 2 0 0 9. 0 0 2 89. x.
    • (2009) Br J Pharmacol , vol.157 , pp. 151-152
    • Takeda, K.1
  • 26
    • 84866899464 scopus 로고    scopus 로고
    • Endgame: Glybera finally recommended for approval as the first gene therapy drug in the European union
    • PMID:23023051
    • Ylä-Herttuala S. Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union. Mol Ther 2012; 20:1831-2; PMID:23023051; http://dx.doi.org/10.1038/mt.2012.194.
    • (2012) Mol Ther , vol.20 , pp. 1831-1832
    • Ylä-Herttuala, S.1
  • 27
    • 75149145129 scopus 로고    scopus 로고
    • The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF(165)
    • PMID:20044134
    • Keeney M, van den Beucken JJJP, van der Kraan PM, Jansen JA, Pandit A. The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF(165). Biomaterials 2010; 31:2893-902; PMID:20044134; http://dx.doi.org/10.1016/j. biomaterials.2009.12.041.
    • (2010) Biomaterials , vol.31 , pp. 2893-2902
    • Keeney, M.1    Van Den Beucken, J.J.J.P.2    Van Der Kraan, P.M.3    Jansen, J.A.4    Pandit, A.5
  • 28
    • 33646337916 scopus 로고    scopus 로고
    • Bone regeneration by modified gene-activated matrix: Effectiveness in segmental tibial defects in rats
    • Endo M, Kuroda S, Kondo H, Maruoka Y, Ohya K, Kasugai S. Bone regeneration by modified gene-activated matrix: effectiveness in segmental tibial defects in rats. Tissue Eng 2006; 12:489-97; PMID:16579682; http://dx.doi.org/10.1089/ten.2006.12.489. (Pubitemid 43673454)
    • (2006) Tissue Engineering , vol.12 , Issue.3 , pp. 489-497
    • Endo, M.1    Kuroda, S.2    Kondo, H.3    Maruoka, Y.4    Ohya, K.5    Kasugai, S.6
  • 29
    • 34548065400 scopus 로고    scopus 로고
    • Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles
    • DOI 10.1038/sj.mt.6300218, PII 6300218
    • Itaka K, Ohba S, Miyata K, Kawaguchi H, Nakamura K, Takato T, et al. Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles. Mol Ther 2007; 15:1655-62; PMID:17551504; http://dx.doi.org/10. 1038/sj.mt.6300218. (Pubitemid 47289009)
    • (2007) Molecular Therapy , vol.15 , Issue.9 , pp. 1655-1662
    • Itaka, K.1    Ohba, S.2    Miyata, K.3    Kawaguchi, H.4    Nakamura, K.5    Takato, T.6    Chung, U.-I.7    Kataoka, K.8
  • 30
    • 77955485475 scopus 로고    scopus 로고
    • Gene therapy for bone healing
    • PMID:20569532
    • Evans CH. Gene therapy for bone healing. Expert Rev Mol Med 2010; 12:e18; PMID:20569532; http://dx.doi.org/10.1017/S1462399410001493.
    • (2010) Expert Rev Mol Med , vol.12
    • Evans, C.H.1
  • 31
    • 81755166844 scopus 로고    scopus 로고
    • Barriers to the clinical translation of orthopedic tissue engineering
    • PMID:21682607
    • Evans CH. Barriers to the clinical translation of orthopedic tissue engineering. Tissue Eng Part B Rev 2011; 17:437-41; PMID:21682607; http://dx.doi.org/10.1089/ten.teb.2011.0228.
    • (2011) Tissue Eng Part B Rev , vol.17 , pp. 437-441
    • Evans, C.H.1
  • 32
    • 82155171283 scopus 로고    scopus 로고
    • Orthopedic gene therapy-lost in translation?
    • PMID:21948071
    • Evans CH, Ghivizzani SC, Robbins PD. Orthopedic gene therapy-lost in translation? J Cell Physiol 2012; 227:416-20; PMID:21948071; http://dx.doi.org/10.1002/jcp.23031.
    • (2012) J Cell Physiol , vol.227 , pp. 416-420
    • Evans, C.H.1    Ghivizzani, S.C.2    Robbins, P.D.3
  • 33
    • 77953683526 scopus 로고    scopus 로고
    • Genetically modified cells in regenerative medicine and tissue engineering
    • PMID:20114067
    • Sheyn D, Mizrahi O, Benjamin S, Gazit Z, Pelled G, Gazit D. Genetically modified cells in regenerative medicine and tissue engineering. Adv Drug Deliv Rev 2010; 62:683-98; PMID:20114067; http://dx.doi.org/10.1016/j.addr.2010.01. 002.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 683-698
    • Sheyn, D.1    Mizrahi, O.2    Benjamin, S.3    Gazit, Z.4    Pelled, G.5    Gazit, D.6
  • 34
    • 79951686783 scopus 로고    scopus 로고
    • Non-viral gene delivery to mesenchy-mal stem cells: Methods, strategies and application in bone tissue engineering and regeneration
    • PMID:21182464
    • Santos JL, Pandita D, Rodrigues J, Pêgo A P, Granja PL, Tomás H. Non-viral gene delivery to mesenchy-mal stem cells: methods, strategies and application in bone tissue engineering and regeneration. Curr Gene Ther 2011; 11:46-57; PMID:21182464; http://dx.doi.org/10.2174/ 156652311794520102.
    • (2011) Curr Gene Ther , vol.11 , pp. 46-57
    • Santos, J.L.1    Pandita, D.2    Rodrigues, J.3    Pêgo, A.P.4    Granja, P.L.5    Tomás, H.6
  • 35
    • 68549130637 scopus 로고    scopus 로고
    • Chemical vectors for gene delivery: A current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers
    • PMID:19459843
    • Midoux P, Pichon C, Yaouanc JJ, Jaffrès PA. Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers. Br J Pharmacol 2009; 157:166-78; PMID:19459843; http://dx.doi. o r g/10.1111/j.1476-5381. 2 0 0 9.0 0 2 8 8. x.
    • (2009) Br J Pharmacol , vol.157 , pp. 166-178
    • Midoux, P.1    Pichon, C.2    Yaouanc, J.J.3    Jaffrès, P.A.4
  • 36
    • 0033021062 scopus 로고    scopus 로고
    • Localized, direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration
    • DOI 10.1038/10473
    • Bonadio J, Smiley E, Patil P, Goldstein S. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration. Nat Med 1999; 5:753-9; PMID:10395319; http://dx.doi.org/10.1038/ 10473. (Pubitemid 29318608)
    • (1999) Nature Medicine , vol.5 , Issue.7 , pp. 753-759
    • Bonadio, J.1    Smiley, E.2    Patil, P.3    Goldstein, S.4
  • 38
    • 77953684413 scopus 로고    scopus 로고
    • Nanomaterials for in situ cell delivery and tissue regeneration. [Corrected Proof.]
    • PMID:20156499
    • Wan ACA, Ying JY. Nanomaterials for in situ cell delivery and tissue regeneration. [Corrected Proof.]. Adv Drug Deliv Rev 2010; 62:731-40; PMID:20156499; http://dx.doi.org/10.1016/j. addr.2010.02.002.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 731-740
    • Wan, A.C.A.1    Ying, J.Y.2
  • 39
    • 0036636194 scopus 로고    scopus 로고
    • Enhancement of tendon-bone integration of anterior cruciate ligament grafts with bone morphogenetic protein-2 gene transfer: A his-tological and biomechanical study
    • PMID:12107310
    • Martinek V, Latterman C, Usas A, Abramowitch S, Woo SL, Fu FH, et al. Enhancement of tendon-bone integration of anterior cruciate ligament grafts with bone morphogenetic protein-2 gene transfer: a his-tological and biomechanical study. J Bone Joint Surg Am 2002; 84-A:1123-31; PMID:12107310.
    • (2002) J Bone Joint Surg Am , vol.84 A , pp. 1123-1131
    • Martinek, V.1    Latterman, C.2    Usas, A.3    Abramowitch, S.4    Woo, S.L.5    Fu, F.H.6
  • 40
    • 23744467071 scopus 로고    scopus 로고
    • Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I)
    • DOI 10.1038/sj.gt.3302515
    • Madry H, Kaul G, Cucchiarini M, Stein U, Zurakowski D, Remberger K, et al. Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I). Gene Ther 2005; 12:1171-9; PMID:15815701; http://dx.doi.org/10.1038/sj.gt.3302515. (Pubitemid 41136311)
    • (2005) Gene Therapy , vol.12 , Issue.15 , pp. 1171-1179
    • Madry, H.1    Kaul, G.2    Cucchiarini, M.3    Stein, U.4    Zurakowski, D.5    Remberger, K.6    Menger, M.D.7    Kohn, D.8    Trippel, S.B.9
  • 41
    • 27644481938 scopus 로고    scopus 로고
    • Porous chitosan-gelatin scaffold containing plasmid DNA encoding transforming growth factor-β1 for chondrocytes proliferation
    • DOI 10.1016/j.biomaterials.2005.08.015, PII S0142961205007684
    • Guo T, Zhao J, Chang J, Ding Z, Hong H, Chen J, et al. Porous chitosan-gelatin scaffold containing plasmid DNA encoding transforming growth factor-beta1 for chondrocytes proliferation. Biomaterials 2006; 27:1095-103; PMID:16143394; http://dx.doi.org/10.1016/j.biomaterials.2005.08.015. (Pubitemid 41566703)
    • (2006) Biomaterials , vol.27 , Issue.7 , pp. 1095-1103
    • Guo, T.1    Zhao, J.2    Chang, J.3    Ding, Z.4    Hong, H.5    Chen, J.6    Zhang, J.7
  • 42
    • 35348942941 scopus 로고    scopus 로고
    • Genetic manipulation of human mesenchymal progenitors to promote chondrogenesis using "bead-in-bead" polysaccharide capsules
    • DOI 10.1016/j.biomaterials.2007.09.006, PII S0142961207007235
    • Babister JC, Tare RS, Green DW, Inglis S, Mann S, Oreffo RO. Genetic manipulation of human mesen-chymal progenitors to promote chondrogenesis using "bead-in-bead" polysaccharide capsules. Biomaterials 2008; 29:58-65; PMID:17897711; http://dx.doi.org/10.1016/j.biomaterials.2007.09.006. (Pubitemid 47610692)
    • (2008) Biomaterials , vol.29 , Issue.1 , pp. 58-65
    • Babister, J.C.1    Tare, R.S.2    Green, D.W.3    Inglis, S.4    Mann, S.5    Oreffo, R.O.C.6
  • 43
    • 39749180922 scopus 로고    scopus 로고
    • Cell-based resurfacing of large cartilage defects: Long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis
    • DOI 10.1002/art.23124
    • Gelse K, Mühle C, Franke O, Park J, Jehle M, Durst K, et al. Cell-based resurfacing of large cartilage defects: long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis. Arthritis Rheum 2008; 58:475-88; PMID:18240212; http://dx.doi.org/10.1002/art.23124. (Pubitemid 351294882)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.2 , pp. 475-488
    • Gelse, K.1    Muhle, C.2    Franke, O.3    Park, J.4    Jehle, M.5    Durst, K.6    Goken, M.7    Hennig, F.8    Von Der Mark, K.9    Schneider, H.10
  • 45
    • 0034737742 scopus 로고    scopus 로고
    • Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase
    • DOI 10.1074/jbc.275.13.9645
    • Jaiswal RK, Jaiswal N, Bruder SP, Mbalaviele G, Marshak DR, Pittenger MF. Adult human mesen-chymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-acti-vated protein kinase. J Biol Chem 2000; 275:9645-52; PMID:10734116; http://dx.doi.org/10.1074/jbc.275.13. 9645. (Pubitemid 30185197)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.13 , pp. 9645-9652
    • Jaiswal, R.K.1    Jaiswal, N.2    Bruder, S.P.3    Mbalaviele, G.4    Marshak, D.R.5    Pittenger, M.F.6
  • 47
    • 84858701204 scopus 로고    scopus 로고
    • The development of non-viral gene-activated matrices for bone regeneration using poly-ethyleneimine (PEI) and collagen-based scaffolds
    • PMID:22138069
    • Tierney EG, Duffy GP, Hibbitts AJ, Cryan S-A, O'Brien FJ. The development of non-viral gene-activated matrices for bone regeneration using poly-ethyleneimine (PEI) and collagen-based scaffolds. J Control Release 2012; 158:304-11; PMID:22138069; http://dx.doi.org/10.1016/j.jconrel.2011.11.026.
    • (2012) J Control Release , vol.158 , pp. 304-311
    • Tierney, E.G.1    Duffy, G.P.2    Hibbitts, A.J.3    Cryan, S.-A.4    O'Brien, F.J.5
  • 48
    • 77952479267 scopus 로고    scopus 로고
    • Efficient transfer of reporter gene-loaded nanoparticles to bone marrow stromal cells (D1) by reverse transfection
    • PMID:20358915
    • Nguyen YT, Kim HK, Kwon JS, Kim YS, Yoon TR, Ahn Y, et al. Efficient transfer of reporter gene-loaded nanoparticles to bone marrow stromal cells (D1) by reverse transfection. J Nanosci Nanotechnol 2010; 10:3170-4; PMID:20358915; http://dx.doi.org/10.1166/jnn.2010.2236.
    • (2010) J Nanosci Nanotechnol , vol.10 , pp. 3170-3174
    • Nguyen, Y.T.1    Kim, H.K.2    Kwon, J.S.3    Kim, Y.S.4    Yoon, T.R.5    Ahn, Y.6
  • 49
    • 84860400943 scopus 로고    scopus 로고
    • Linear polyethylenimine-graft-chitosan copo-lymers as efficient DNA/siRNA delivery vectors in vitro and in vivo
    • PMID:21756861
    • Tripathi SK, Goyal R, Kumar P, Gupta KC. Linear polyethylenimine-graft- chitosan copo-lymers as efficient DNA/siRNA delivery vectors in vitro and in vivo. Nanomedicine 2012; 8:337-45; PMID:21756861; http://dx.doi.org/10.1016/j. nano.2011.06.022.
    • (2012) Nanomedicine , vol.8 , pp. 337-345
    • Tripathi, S.K.1    Goyal, R.2    Kumar, P.3    Gupta, K.C.4
  • 51
    • 79952615477 scopus 로고    scopus 로고
    • Polyethylenimine-mediated gene delivery into human bone marrow mesenchymal stem cells from patients
    • PMID: 20629995
    • Wang W, Li W, Ou L, Flick E, Mark P, Nesselmann C, et al. Polyethylenimine-mediated gene delivery into human bone marrow mesenchymal stem cells from patients. J Cell Mol Med 2011; 15:1989-98; PMID: 20629995 ; htt p://dx.doi.org/10.1111/j.1582-4934.2010.01130.x.
    • (2011) J Cell Mol Med , vol.15 , pp. 1989-1998
    • Wang, W.1    Li, W.2    Ou, L.3    Flick, E.4    Mark, P.5    Nesselmann, C.6
  • 52
    • 17644377327 scopus 로고    scopus 로고
    • Long-term in vivo gene expression via delivery of PEI-DNA condensates from porous polymer scaffolds
    • DOI 10.1089/hum.2005.16.609
    • Huang YC, Riddle K, Rice KG, Mooney DJ. Longterm in vivo gene expression via delivery of PEI-DNA condensates from porous polymer scaffolds. Hum Gene Ther 2005; 16:609-17; PMID:15916485; http://dx.doi.org/10.1089/hum.2005.16.609. (Pubitemid 40740928)
    • (2005) Human Gene Therapy , vol.16 , Issue.5 , pp. 609-617
    • Huang, Y.-C.1    Riddle, K.2    Rice, K.G.3    Mooney, D.J.4
  • 53
    • 20144373766 scopus 로고    scopus 로고
    • Non-viral gene delivery regulated by stiffness of cell adhesion substrates
    • DOI 10.1038/nmat1392
    • Kong HJ, Liu J, Riddle K, Matsumoto T, Leach K, Mooney DJ. Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat Mater 2005; 4:460-4; PMID:15895097; http://dx.doi.org/10.1038/nmat1392. (Pubitemid 40774051)
    • (2005) Nature Materials , vol.4 , Issue.6 , pp. 460-464
    • Kong, H.J.1    Liu, J.2    Riddle, K.3    Matsumoto, T.4    Leach, K.5    Mooney, D.J.6
  • 54
    • 77953861193 scopus 로고    scopus 로고
    • Biomineralized composite substrates increase gene expression with nonviral delivery
    • Rao R. R., He J, Leach JK. Biomineralized composite substrates increase gene expression with nonviral delivery. J Biomed Mater Res A 2010; 94A:344-54.
    • (2010) J Biomed Mater Res A , vol.94 A , pp. 344-354
    • Rao, R.R.1    He, J.2    Leach, J.K.3
  • 56
    • 84871376530 scopus 로고    scopus 로고
    • High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyl-eneimine-ephrinB2 gene-activated matrix
    • PMID:23201622
    • Tierney EG, McSorley K, Hastings CL, Cryan S-A, O'Brien T, Murphy MJ, et al. High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyl-eneimine-ephrinB2 gene-activated matrix. J Control Release 2013; 165:173-82; PMID:23201622; http://d x.doi.org/10.1016/j. jconrel.2012.11.013.
    • (2013) J Control Release , vol.165 , pp. 173-182
    • Tierney, E.G.1    McSorley, K.2    Hastings, C.L.3    Cryan, S.-A.4    O'Brien, T.5    Murphy, M.J.6
  • 57
    • 5044240692 scopus 로고    scopus 로고
    • Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly
    • DOI 10.1016/j.devcel.2004.09.006, PII S1534580704003272
    • Poliakov A, Cotrina M, Wilkinson DG. Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly. Dev Cell 2004; 7:465-80; PMID:15469835; http://dx.doi.org/10.1016/j.devcel.2004.09.006. (Pubitemid 39341833)
    • (2004) Developmental Cell , vol.7 , Issue.4 , pp. 465-480
    • Poliakov, A.1    Cotrina, M.2    Wilkinson, D.G.3
  • 58
    • 4444227124 scopus 로고    scopus 로고
    • Eph/ephrin signaling in morphogenesis, neural development and plasticity
    • DOI 10.1016/j.ceb.2004.07.002, PII S0955067404000973
    • Klein R. Eph/ephrin signaling in morphogenesis, neural development and plasticity. Curr Opin Cell Biol 2004; 16:580-9; PMID:15363810; http://dx.doi.org/10.1016/j.ceb.2004.07.002. (Pubitemid 39201244)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.5 , pp. 580-589
    • Klein, R.1
  • 59
    • 33746528704 scopus 로고    scopus 로고
    • Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis
    • DOI 10.1016/j.cmet.2006.05.012, PII S1550413106002038
    • Zhao C, Irie N, Takada Y, Shimoda K, Miyamoto T, Nishiwaki T, et al. Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab 2006; 4:111-21; PMID:16890539; http://dx.doi.org/10.1016/j.cmet.2006.05.012. (Pubitemid 44138718)
    • (2006) Cell Metabolism , vol.4 , Issue.2 , pp. 111-121
    • Zhao, C.1    Irie, N.2    Takada, Y.3    Shimoda, K.4    Miyamoto, T.5    Nishiwaki, T.6    Suda, T.7    Matsuo, K.8
  • 61
    • 41149084179 scopus 로고    scopus 로고
    • Eph-ephrin bidirectional signaling in physiology and disease
    • DOI 10.1016/j.cell.2008.03.011, PII S0092867408003863
    • Pasquale EB. Eph-ephrin bidirectional signaling in physiology and disease. Cell 2008; 133:38-52; PMID:18394988; http://dx.doi.org/10.1016/j. cell.2008.03.011. (Pubitemid 351442996)
    • (2008) Cell , vol.133 , Issue.1 , pp. 38-52
    • Pasquale, E.B.1
  • 62
    • 70849112627 scopus 로고    scopus 로고
    • Inspiration and application in the evolution of biomaterials
    • PMID:19940912
    • Huebsch N, Mooney DJ. Inspiration and application in the evolution of biomaterials. Nature 2009; 462:426-32; PMID:19940912; http://dx.doi.org/10.1038/ nature08601.
    • (2009) Nature , vol.462 , pp. 426-432
    • Huebsch, N.1    Mooney, D.J.2
  • 63
    • 84867291582 scopus 로고    scopus 로고
    • Use of BMPs and bisphosphonates in improving bone fracture healing. [Elite Ed]
    • PMID:22652667
    • Yu NY, Schindeler A, Tagil M, Ruys AJ, Little DG. Use of BMPs and bisphosphonates in improving bone fracture healing. [Elite Ed]. Front Biosci (Elite Ed) 2012; 4:2647-53; PMID:22652667; http://dx.doi.org/10.2741/E572.
    • (2012) Front Biosci (Elite Ed) , vol.4 , pp. 2647-2653
    • Yu, N.Y.1    Schindeler, A.2    Tagil, M.3    Ruys, A.J.4    Little, D.G.5
  • 64
    • 77956074155 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpress-ing ephrin-b2 rapidly adopt an early endothelial phenotype with simultaneous reduction of osteo-genic potential
    • PMID:20491587
    • Duffy GP, D'Arcy S, Ahsan T, Nerem RM, O'Brien T, Barry F. Mesenchymal stem cells overexpress-ing ephrin-b2 rapidly adopt an early endothelial phenotype with simultaneous reduction of osteo-genic potential. Tissue Eng Part A 2010; 16:2755-68; PMID:20491587; http://dx.doi.org/10.1089/ten. tea.2009.0623.
    • (2010) Tissue Eng Part A , vol.16 , pp. 2755-2768
    • Duffy, G.P.1    D'Arcy, S.2    Ahsan, T.3    Nerem, R.M.4    O'Brien, T.5    Barry, F.6
  • 65
    • 0025155391 scopus 로고
    • Intracellular distribution of DNA internalized through calcium phosphate precipitation
    • PMID:2209719
    • Orrantia E, Chang PL. Intracellular distribution of DNA internalized through calcium phosphate precipitation. Exp Cell Res 1990; 190:170-4; PMID:2209719; http://dx.doi.org/10.1016/0014-4827(90)90181-9.
    • (1990) Exp Cell Res , vol.190 , pp. 170-174
    • Orrantia, E.1    Chang, P.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.