High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix

Journal of Controlled Release

Volumn 165, Issue 3, 2013, Pages 173-182

  Tierney, Erica G ^a   McSorley, Kevin ^a   Hastings, Conn L ^a   Cryan, Sally Ann ^a   O'Brien, Timothy ^b   Murphy, Mary J ^b   Barry, Frank P ^b   O'Brien, Fergal J ^a,c   Duffy, Garry P ^a,c  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

EphB4; EphrinB2; Gene transfer; Keywords; Mesenchymal stem cells; Osteogenesis; Scaffold

Indexed keywords

EPHB4; EPHRINB2; KEYWORDS; MESENCHYMAL STEM CELL; OSTEOGENESIS;

BONE; CELL MEMBRANES; GENE EXPRESSION; GENE TRANSFER; LIGANDS; SCAFFOLDS; SCAFFOLDS (BIOLOGY); STEM CELLS;

CELL CULTURE;

BONE MORPHOGENETIC PROTEIN 2; EPHRIN B2; EPHRIN RECEPTOR B4; POLYETHYLENEIMINE; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; BONE REMODELING; CELL DIFFERENTIATION; CELL INTERACTION; CONTROLLED STUDY; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MESENCHYMAL STEM CELL; OSTEOBLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

BONE REGENERATION; CELL DIFFERENTIATION; CELLS, CULTURED; DNA; EPHRIN-B2; GENETIC THERAPY; GREEN FLUORESCENT PROTEINS; HUMANS; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PEPTIDES; PLASMIDS; POLYETHYLENEIMINE; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPHB4; TISSUE SCAFFOLDS;

EID: 84871376530     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.11.013     Document Type: Article

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