Platelet-derived growth factor-BB activates calcium/calmodulin-dependent and -independent mechanisms that mediate Akt phosphorylation in the neurofibromin-deficient human Schwann cell line ST88-14

Journal of Biological Chemistry

Volumn 288, Issue 16, 2013, Pages 11066-11073

  Farrer, Robert G ^a   Farrer, Jason R ^a,b   DeVries, George H ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AKT PHOSPHORYLATION; CELL SURVIVAL; GROWTH FACTOR RECEPTORS; INTRACELLULAR CALCIUM; PERIPHERAL NERVES; SCHWANN CELLS; SUSTAINED ACTIVATION; TUMOR FORMATION;

CAMS; CELL CULTURE; CELL DEATH; NEURONS; PHOSPHORYLATION; TUMORS;

CALMODULIN;

1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL)ESTER; CALCIUM; CALCIUM CHELATING AGENT; CALMODULIN; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; NEUROFIBROMIN; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENICITY; CELL STIMULATION; CELL STRAIN ST88 14; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALIGNANT PERIPHERAL NERVE SHEATH TUMOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SCHWANN CELL; SIGNAL TRANSDUCTION;

ANGIOGENESIS INDUCING AGENTS; CALCIUM; CALMODULIN; CELL LINE; CHELATING AGENTS; EGTAZIC ACID; ENZYME INHIBITORS; HUMANS; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-SIS; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SCHWANN CELLS; SULFONAMIDES;

EID: 84876559631     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.442244     Document Type: Article

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