Neprilysin deficiency protects against fat-induced insulin secretory dysfunction by maintaining calcium influx

Diabetes

Volumn 62, Issue 5, 2013, Pages 1593-1601

  Zraika, Sakeneh ^a   Koh, Duk Su ^a   Barrow, Breanne M ^a   Lu, Bao ^b   Kahn, Steven E ^a   Andrikopoulos, Sofianos ^c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA ACTIN; CALCIUM CHANNEL; FATTY ACID; GLUCOSE; INSULIN; MEMBRANE METALLOENDOPEPTIDASE; MESSENGER RNA; POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME DEFICIENCY; FEMALE; GENOTYPE; IN VITRO STUDY; INHIBITION KINETICS; INSULIN RELEASE; LIPID DIET; MALE; MOUSE; NITRATIVE STRESS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLOOD GLUCOSE; CALCIUM SIGNALING; DIET, HIGH-FAT; DOWN-REGULATION; FATTY ACIDS, NONESTERIFIED; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE INTOLERANCE; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEPRILYSIN; PANCREAS; RECOMBINANT PROTEINS; RNA, MESSENGER; TISSUE CULTURE TECHNIQUES; UP-REGULATION;

EID: 84876558590     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1593     Document Type: Article

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