Rv1894c Is a novel hypoxia-induced nitronate monooxygenase required for mycobacterium tuberculosis virulence

Journal of Infectious Diseases

Volumn 207, Issue 10, 2013, Pages 1525-1534

  Klinkenberg, Lee G ^a   Karakousis, Petros C ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

2 nitropropane dioxygenase; animal models; detoxification; dormancy; fatty acid synthesis; guinea pig; latency; latent tuberculosis infection; lipids; Mycobacterium tuberculosis; nitroalkane; oxidation; persistence; Pseudomonas aeruginosa; virulence

Indexed keywords

NITRONATE MONOOXYGENASE; PROTEIN KSTR; REPRESSOR PROTEIN; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; GRANULOMA; GUINEA PIG; HISTOPATHOLOGY; HYPOXIA; LUNG PARENCHYMA; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NEGATIVE FEEDBACK; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RV1894C GENE;

AMINO ACID SEQUENCE; ANIMALS; ANOXIA; BACTERIAL PROTEINS; CLONING, MOLECULAR; DISEASE MODELS, ANIMAL; ENDPOINT DETERMINATION; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENOTYPE; GUINEA PIGS; LUNG; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; VIRULENCE;

EID: 84876555014     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit049     Document Type: Article

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