Antihyperlipidaemic and antioxidant effect of the total flavonoids in Selaginella tamariscina (Beauv.) Spring in diabetic mice

Journal of Pharmacy and Pharmacology

Volumn 65, Issue 5, 2013, Pages 757-766

  Zheng, Xiao Ke ^a   Wang, Wei Wei ^a   Zhang, Li ^a   Su, Cheng Fu ^a   Wu, Yong Yong ^a   Ke, Ying Ying ^a   Hou, Qing Wei ^a   Liu, Zhao Yan ^a   Gao, Ai She ^a   Feng, Wei Sheng ^a  

^a HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

antihyperlipidaemic; antioxidant; flavonoids; Selaginella tamariscina (Beauv.) Spring; visfatin

Indexed keywords

CATALASE; CHOLESTEROL; FATTY ACID; FLAVONOID; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; METFORMIN; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NITRIC OXIDE; PLANT EXTRACT; SELAGINELLA TAMARISCINA EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIHYPERLIPIDEMIC EFFECT; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; FATTY ACID BLOOD LEVEL; FATTY LIVER; GLUCOSE BLOOD LEVEL; HERBAL MEDICINE; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PROTEIN SYNTHESIS; SELAGINELLA TAMARISCINA; STREPTOZOCIN DIABETES;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIET, HIGH-FAT; FATTY ACIDS, NONESTERIFIED; FATTY LIVER; FLAVONOIDS; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; INSULIN; INSULIN RESISTANCE; LIPIDS; LIVER; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED STRAINS; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHYTOTHERAPY; PLANT EXTRACTS; SELAGINELLACEAE;

EID: 84876470835     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12035     Document Type: Article

References (35)

1. Whiting DR, et al. IDF Diabetes Atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract 2011; 94: 311-321.
2. Jin L, et al. Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes. Eur J Pharmacol 2008; 582: 162-167.
3. Robertson RP, et al. Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 2004; 53 (Suppl. 1): S119-S124.
4. Cusi K,. The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes. Curr Diab Rep 2010; 10: 306-315.
5. Herpen NV, Hinderling VS,. Lipid accumulation in non-adipose tissue and lipotoxicity. Physiol Behav 2008; 94: 231-241.
6. Ryu S, et al. Oxidative stress in Cohen diabetic rat model by high-sucrose, low-copper diet: inducing pancreatic damage and diabetes. Metabolism 2008; 57: 1253-1261.
7. Dixit PP, et al. Formulated antidiabetic preparation Syndrex has a strong antioxidant activity. Eur J Pharmacol 2008; 581: 216-225.
8. Gupta RK, et al. In vivo evaluation of anti-oxidant and anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. J Ethnopharmacol 2008; 118: 21-25.
9. Noiri E, Tsukahara H,. Parameters for measurement of oxidative stress in diabetes mellitus: applicability of enzyme-linked immunosorbent assay for clinical evaluation. J Investig Med 2005; 53: 167-175.
10. Rolo AP, Palmeira CM,. Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol 2006; 212: 167-178.
11. Majumdar S, et al. Comparative in vitro free radical scavenging activity of some indigenous plants. Int J Pharm Tech Res 2010; 2: 1046-1049.
12. Rajeshwar Y, et al. Antitumor activity and in vivo antioxidant status of Mucuna pruriens (Fabaceae) seeds against Ehrlich ascites carcinoma in Swiss albino mice. Iran J Pharm Ther 2005; 4: 46-53.
13. Zheng XK, et al. Anti-diabetic activity and potential mechanism of total flavonoids of Selaginella tamariscina (Beauv.) Spring in rats induced by high fat diet and low dose STZ. J Ethnopharmacol 2011; 137: 662-668.
14. Zheng XK, et al. Antihyperglycemic activity of Selaginella tamariscina (Beauv.) Spring. J Ethnopharmacol 2011; 133: 531-537.
15. Zhao XM, et al. Studies on chemical constitutes of antihyperlipidemia effective part in selaginella tamariscina. Chinese Herbal Medicines 2009; 40: 1712-1715.
16. Vedavanam K, et al. Antioxidant action and potential antidiabetic properties of an isoflavonoid-containing soyabean phytochemical extract (SPE). Phytother Res 1999; 13: 601-608.
17. Wang JQ, et al. Preventive effects of total flavonoids of Litsea coreana leve on hepatic steatosis in rats fed with high fat diet. J Ethnopharmacol 2009; 121: 54-60.
18. Zhang L, et al. Antidiabetic and antioxidant effects of extracts from Potentilla discolor Bunge on diabetic rats induced by high fat diet and streptozotocin. J Ethnopharmacol 2010; 132: 518-524.
19. WHO. Definition, diagnosis and classification of diabetes mellitus and its complications. WHO/NCD/NCS/99.2 1999.
20. Bagri P, et al. Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Food Chem Toxicol 2009; 47: 50-54.
21. Luo J, et al. Nongenetic mouse models of non-insulin-dependent diabetes mellitus. Metabolism 1998; 47: 663-668.
22. Surwit RS, et al. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 1988; 37: 1163-1167.
23. Badole SL, Bodhankar SL,. Investigation of antihyperglycaemic activity of aqueous and petroleum ether extract of stem bark of Pongamia pinnata on serum glucose level in diabetic mice. J Ethnopharmacol 2009; 123: 115-120.
24. Group TDCaCTR. The effect of intensive treatment of diabetes on the development and progression of longterm complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329: 977-986.
25. Shaw JE, et al. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010; 87: 4-14.
26. Goldberg R,. Lipid disorders in diabetes. Diabetes Care 1981; 4: 561-572.
27. Trauner M, et al. Fatty liver and lipotoxicity. Biochim Biophys Acta 2010; 1801: 299-310.
28. Bobulescu I., Renal lipid metabolism and lipotoxicity. Curr Opin Nephrol Hypertens 2010; 19: 393-402.
29. Esteghamati A, et al. Serum visfatin is associated with type 2 diabetes mellitus independent of insulin resistance and obesity. Diabetes Res Clin Pract 2011; 91: 154-158.
30. Fukuhara A, et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 2005; 307: 426-430.
31. Haider DG, et al. The release of the adipocytokine visfatin is regulated by glucose and insulin. Diabetologia 2006; 49: 1909-1914.
32. Bermejo AL, et al. Serum visfatin increases with progressive beta-cell deterioration. Diabetes 2006; 55: 2871-2875.
33. Chen MP, et al. Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. JCEM 2006; 91: 295-299.
34. Ramachandran S, et al. Investigation of antidiabetic, antihyperlipidemic, and in vivo antioxidant properties of Sphaeranthus indicus linn. In type 1 diabetic rats: an identification of possible biomarkers. Evid Based Complement Alternat Med 2011; pii: 571721.
35. Aktan F,. iNOS-mediated nitric oxide production and its regulation. Life Sci 2004; 75: 639-653.