Propolis protects CYP 2E1 enzymatic activity and oxidative stress induced by carbon tetrachloride

Molecular and Cellular Biochemistry

Volumn 302, Issue 1-2, 2007, Pages 215-224

  Bhadauria, Monika ^a,b   Nirala, Satendra Kumar ^a   Shukla, Sangeeta ^a  

^a JIWAJI UNIVERSITY   (India)

^b LANZHOU UNIVERSITY   (China)

Author keywords

Carbon tetrachloride; CYP 2E1; Drug metabolizing enzymes; Hepatoprotection; Liver function test; Oxidative stress; Propolis

Indexed keywords

AMINOPYRINE N DEMETHYLASE; BROMSULFOPHTHALEIN; CARBON TETRACHLORIDE; CHOLERETIC AGENT; CYTOCHROME P450 2E1; GAMMA GLUTAMYLTRANSFERASE; HEXOBARBITAL; LACTATE DEHYDROGENASE; MALONALDEHYDE; PROPOLIS; SILYMARIN; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; FEMALE; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER MICROSOME; LIVER PROTECTION; LIVER STRUCTURE; LIVER TOXICITY; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; RAT;

AMINOPYRINE N-DEMETHYLASE; ANILINE HYDROXYLASE; ANIMALS; CARBON TETRACHLORIDE; CHOLAGOGUES AND CHOLERETICS; CYTOCHROME P-450 CYP2E1; GAMMA-GLUTAMYLTRANSFERASE; HEXOBARBITAL; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; LIVER; MICROSOMES, LIVER; OXIDATIVE STRESS; PROPOLIS; PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; REST; SLEEP;

RATTUS;

EID: 34547632384     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9443-4     Document Type: Article

References (49)

1. Nan JX, Jiang YZ, Park EJ, Ko G, Kim YC, Sohm DH (2003) Protective effect of Rhodiola sachalinesis extract on carbon tetrachloride induced liver injury in rats. J Ethnopharmacol 84:143-148
2. Lee TY, Mai LM, Wang GJ, Chiu JH, Lin YL, Lin HC (2003) Protective mechanism of Salvia miltiorrhiza on carbon tetrachloride induced hepatotoxicity in rats. J Pharmacol Sci 91:202-210
3. Pohl L, Schulick R, Highet R, George J (1983) Identification of dichloromethyl carbine as a metabolite of carbon tetrachloride. Biochem Biophys Res Commun 117:367-384
4. Pohl L, Schulick R, George J (1986) Reductive oxygenation mechanism of metabolism of carbon tetrachloride to phosgene by cytochrome P450. Mol Pharmacol 25:318-324
5. Bhat VB, Madyastha KM (2000) C-phycocyanin: A potent peroxyl radical scavenger in vivo and in vitro. Biochem Biophy Res Commun 275:20-25
6. Recknagel RO, Glande EA Jr (1973) Carbon tetrachloride hepatotoxicity: an example of lethal cleavage. Critical Rev Toxicol 2:263-297
7. 4 induced hepatotoxicity in mice. Life Sci 66:265-270
8. Burdock GA (1998) Review of the biological properties and toxicity of bee propolis (propolis). Food Chem Toxicol 36:347-368
9. Banskota AH, Tezuka Y, Kodata Sh (2001) Recent progress in pharmacological research of propolis. Phytother Res 15:561-571
10. Simoes LMC, Gregofio LE, Da Silva Filho AA, de Sauza ML, Azzolini AECS, Bastos JK, Lucisano-Valim YM (2004) Effect of Brazilian green propolis on the production of reactive oxygen species by stimulated neutrophils. J Ethnopharmacol 94:59-65
11. Moreno MIN, Isla ML, Sampietro AR, Vattuone MA (2000) Comparison of the free radical scavenging activity of propolis from several region of Argentina. J Ethnopharmacol 71:109-114
12. Banskota AH, Tezuka Y, Adnyana IK, Midorikawa K, Matsushige K, Message D, Huertas AAG, Kodata S (2000) Cytotoxic, hepatoprotective and free radical scavenging effects of propolis from Brazil, Peru, the Netherlands and China. J Ethnopharmacol 72:249-256
13. Dobrowolski JW, Vohora SB, Sharma K, Shah SK, Naqvi SAH, Dandiya PC (1991) Antibacterial, antifngal, antiamoebic, antiinflammatory and antipyretic studies on propolis bee products. J Ethnopharmacol 35:77-82
14. Kartal M, Yildiz S, Kaya S, Kurucu S, Topcu G (2003) Antimicrobial activity of propolis samples from two different regions of Anatolia. J Ethnopharmacol 86:69-73
15. Banskota AH, Nagaoka T, Sumioka LY, Tezuka Y, Awale S, Midorikawa K, Matsushige K, Kadota S (2002) Antiproliferative activity on the Netherland propolis and its active principles in cancer cell lines. J ethnopharmacol 80:67-73
16. Ivonavska ND, Dimov VB, Pavlova S, Bankova VS, Popov SS (1995) Immunomodulatory action of propolis. V. Anticomplementary activity of a water soluble derivative. J Ethnopharmacol 47:135-143
17. Taraphdar AK, Roy M, Bhattacharya RK (2001) Natural products as inducers of apoptosis: Implication for cancer therapy and prevention. Curr Sci 80:1387-1396
18. Park SH, Min TS (2006) Caffeic acid phenethyl ester ameliorates changes in IGFs secretion and gene expression in streptozotocin-induced diabetic rats. Life Sciences 78:1741-1747
19. Tsai SK, Lin MJ, Liao PH, Yang CY, Lin SM, Liu SM, Lin RH, Chih CL, Huang SS (2006) Caffeic acid phenethyl ester ameliorates cerebral infarction in rats subjected to focal cerebral ischemia. Life Sciences 78:2758-2762
20. Shukla S, Bhadauria M, Jadon A (2004) Effect of propolis extract on acute carbon tetrachloride induced hepatotoxicity. Indian J Exp Biol 42:993-997
21. Shukla S, Bhadauria M, Jadon A (2005) Evaluation of hepatoprotective potential of propolis extract in carbon tetrachloride induced liver injury in rats. Indian J Biochem Biophys 42:321-325
22. Wroblewski F, La Due JS: Colorimetric method for LDH. In: Wootton IDP (ed) Microanalysis in Medical Biochemistry 4th. Edn. J. and A. Churchill Ltd. 104 Gloucester Place 1955, pp 115-118
23. Schenkman JB, Cinti DL (1978) Prepareation of microsomes from calcium. Methods Enzymol 52:83-89
24. Kato R, Gillette JR (1965) Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes. J Pharmacol Exp Ther 150:285-291
25. Cochin J, Axelrod J (1959) Biochemical pharmacological changes in the rats following chronic administration of morphine nalorphine and normorphine. J Pharmacol Exp Ther 125:105-110
26. Sharma SK, Krishna Murti CR (1968) Production of lipidperoxides of brain. J Neurochem 15:147-149
27. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193:265-275
28. Fujimoto JM, Pearce KB, Plaa GL (1960) Barbitone metabolism as affected by certain agents acting on the liver. J Phamacol Exp Ther 129:139-143
29. Kutob SD, Plaa GL (1962) Assessmant of liver function in mice with bromosulphalein. J Appl Physiol 17:123-125
30. Klaassen CD, Plaa GL (1968) Effect of carbon tetrachloride on the metabolism, storage and excretion of sulfobromophthalein. Toxicol Appl Pharmacol 12:132-139
31. Mcmanus FA, Mowry RW (1965) Staining methods. In: Hoeber PB (eds) Histology and histochemistry. Harper and Brothers, NewYork
32. Hayat A, Arif M (1970) Biological Applications. In: Principle and Techniques of Electron Microscopy. Van Nostrard Reinhold Company, New York
33. Snedecor GW, Cochran WG: Statistical Method, 8th Edition. Iowa State University Press, Ames, Iowa
34. Goepter AR, Scheerens H, Vermeulen NP (1995) Oxygen and xenobiotics reductase activities in cytochrome P450. Crit Rev Toxicol 25:25-65
35. Seki M, Kasama K, Imai K (2000) Effect of food restriction on hepatotoxicity of carbon tetrachloride in rats. J Toxicol Sci 25:33-40
36. Jayatilaka KA, Thabrew MI, Perara DJ (1990) Effect of Melothria maderaspatana on carbon tetrachloride-induced changes in rat hepatic microsomal drug-metabolizing enzyme activity. J Ethnopharmacol 30:97-105
37. Aliya R, Okoye ZSC, Shier WT (1995) The hepatoprotective cytochrome P-450 enzyme inhibitor isolated from the Nigerian medicinal plant Cochlospermum planchonii is a zinc salt. J Ethanopharmacol. 48:89-97
38. Balasubramaniyan V, Sailja KJ, Nalini N (2003) Role of leptin on alcohol induced oxidative stress in swiss mice. Pharmacol Res 47:211-216
39. Anand KK, Singh B, Saxena AK, Chandan BK, Gupta VN, Bhardwaj V (1997) 3, 4, 5-trihydroxy benzoic acid (gallic acid), the hepatoprotective principle in the fruits of Terminalia belerica bioassay guided activity. Pharmacol Res 36(4):315-321
40. Anand KK, Singh B, Chand D, Chandan BK (1992) An evaluation of Lawsonia alba extract as hepatoprotective agent. Planta Medica 58:22-25
41. Singh B, Saxena AK, Chandan BK, Agrawal SG, Anand KK (2001) In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves. Indian J Physiol Pharmacol 45(4):435-441
42. 4 induced liver damage. J Ethnopharmacol 47:43-47
43. Chandan BK, Sharma AK, Anand KK (1991) Boerhaavia diffusa: A study of its hepatoprotective activity. J Ethnopharmacol 31:299-307
44. Singh B, Saxena AK, Chandan BK, Agarwal SG, Bhatia MS, Anand KK (1993) Hepatoprotective effect of ethanolic extract of Eclipta alba on experimental liver damage in rats and mice. Phytother Res 7:154-158
45. Bhaumik A, Sharma S (1993) Therapeutic efficacy of two herbal preparations in induced hapatopathy in sheep. J Res Edu Ind Med 12(1):33-42
46. Anand KK, Singh B, Saxena AK, Chandan BK, Gupta VN (1994) Hepatoprotective studies of a fraction from the fruits of Terminalia belerica Roxb. on experimental liver injury in rodents. Phytother Res 8:287-292
47. Asha VV (2001) Preliminary studies on the hepatoprotective activity of Mamordica subangulata and Maragamia alata. Indian J Pharmacol 33:276-279
48. Sallie R, Tredger JM, Williams R (1991) Drugs and the liver. Part 1: testing liver function. Biopharm Drug Dispos. 12:251-259
49. Tsai CC, Kao CT, Hsu CT, Lin CC, Lin JC (1997) Evaluation of four prescriptions of traditional Chinese medicine: Syh-mo-yiin, guizhi-fuling-wan, shieh-qing-wan and syh-nih-sann on experimental acute liver damage in rats. J Pharmacol. 55:213-222