Swainsonine activates mitochondria-mediated apoptotic pathway in human lung cancer A549 cells and retards the growth of lung cancer xenografts

International Journal of Biological Sciences

Volumn 8, Issue 3, 2012, Pages 394-405

  Li, Zhaocai ^a   Xu, Xingang ^a   Huang, Yong ^a   Ding, Li ^a   Wang, Zhisheng ^a   Yu, Gaoshui ^a   Xu, Dan ^a   Li, Wei ^a   Tong, Dewen ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

A549 cells; Apoptosis; Caspase; Mitochondrial pathway; Swainsonine

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE 3; CASPASE 9; SWAINSONINE; TUMOR PROTEIN;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LUNG TUMOR; MITOCHONDRION; MOUSE; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; TRANSPLANTATION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIA; NEOPLASM PROTEINS; SWAINSONINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84863235165     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.3882     Document Type: Article

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