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Volumn 33, Issue 4, 2013, Pages 557-566

Neurovascular protection by targeting early blood-brain barrier disruption with neurotrophic factors after ischemia-reperfusion in rats *

Author keywords

blood'brain barrier; epidermal growth factor; ischemia reperfusion injury; magnetic resonance imaging; pigment epithelium derived factor; stroke

Indexed keywords

EPIDERMAL GROWTH FACTOR; NEUROTROPIN; PEPTIDE; PIGMENT EPITHELIUM DERIVED FACTOR;

EID: 84876417600     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2012.201     Document Type: Article
Times cited : (28)

References (42)
  • 1
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999; 22: 391-397.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 2
    • 43249116466 scopus 로고    scopus 로고
    • A new penumbra: Transitioning from injury into repair after stroke
    • Lo EH. A new penumbra: transitioning from injury into repair after stroke. Nat Med 2008; 14: 497-500.
    • (2008) Nat Med , vol.14 , pp. 497-500
    • Lo, E.H.1
  • 3
    • 38549119939 scopus 로고    scopus 로고
    • Early beneficial effect of matrix metalloproteinase inhibition on blood-brain barrier permeability as measured by magnetic resonance imaging countered by impaired long-term recovery after stroke in rat brain
    • Sood RR, Taheri S, Candelario-Jalil E, Estrada EY, Rosenberg GA. Early beneficial effect of matrix metalloproteinase inhibition on blood-brain barrier permeability as measured by magnetic resonance imaging countered by impaired long-term recovery after stroke in rat brain. J Cereb Blood Flow Metab 2008; 28: 431-438.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 431-438
    • Sood, R.R.1    Taheri, S.2    Candelario-Jalil, E.3    Estrada, E.Y.4    Rosenberg, G.A.5
  • 4
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson A, Collin T, Kirik D, Kokaia Z, Lindvall O. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002; 8: 963-970.
    • (2002) Nat Med , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 5
    • 0030928225 scopus 로고    scopus 로고
    • Pharmacology of neurotrophic factors
    • Hefti F. Pharmacology of neurotrophic factors. Annu Rev Pharmacol Toxicol 1997; 37: 239-267.
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 239-267
    • Hefti, F.1
  • 6
    • 59349110661 scopus 로고    scopus 로고
    • Brain inflammation and adult neurogenesis: The dual role of microglia
    • Ekdahl CT, Kokaia Z, Lindvall O. Brain inflammation and adult neurogenesis: the dual role of microglia. Neuroscience 2009; 158: 1021-1029.
    • (2009) Neuroscience , vol.158 , pp. 1021-1029
    • Ekdahl, C.T.1    Kokaia, Z.2    Lindvall, O.3
  • 7
    • 8444231250 scopus 로고    scopus 로고
    • Role of inflammation in the neurobiology of stem cells
    • Simard AR, Rivest S. Role of inflammation in the neurobiology of stem cells. Neuroreport 2004; 15: 2305-2310.
    • (2004) Neuroreport , vol.15 , pp. 2305-2310
    • Simard, A.R.1    Rivest, S.2
  • 8
    • 33747893515 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy
    • Zhang SX, Wang JJ, Gao G, Parke K, Ma JX. Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy. J Mol Endocrinol 2006; 37: 1-12.
    • (2006) J Mol Endocrinol , vol.37 , pp. 1-12
    • Zhang, S.X.1    Wang, J.J.2    Gao, G.3    Parke, K.4    Ma, J.X.5
  • 9
    • 0000912287 scopus 로고    scopus 로고
    • Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia-and free radical-induced injuries
    • Peng H, Wen TC, Tanaka J, Maeda N, Matsuda S, Desaki J et al. Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia-and free radical-induced injuries. J Cereb Blood Flow Metab 1998; 18: 349-360.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 349-360
    • Peng, H.1    Wen, T.C.2    Tanaka, J.3    Maeda, N.4    Matsuda, S.5    Desaki, J.6
  • 10
    • 71949096119 scopus 로고    scopus 로고
    • Cerebral ischemia-reperfusion injury in rats-a 3 T MRI study on biphasic blood-brain barrier opening and the dynamics of edema formation
    • Pillai DR, Dittmar MS, Baldaranov D, Heidemann RM, Henning EC, Schuierer G et al. Cerebral ischemia-reperfusion injury in rats-a 3 T MRI study on biphasic blood-brain barrier opening and the dynamics of edema formation. J Cereb Blood Flow Metab 2009; 29: 1846-1855.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1846-1855
    • Pillai, D.R.1    Dittmar, M.S.2    Baldaranov, D.3    Heidemann, R.M.4    Henning, E.C.5    Schuierer, G.6
  • 11
    • 53749096762 scopus 로고    scopus 로고
    • Blood-brain barrier tight junction permeability and ischemic stroke
    • Sandoval KE, Witt KA. Blood-brain barrier tight junction permeability and ischemic stroke. Neurobiol Dis 2008; 32: 200-219.
    • (2008) Neurobiol Dis , vol.32 , pp. 200-219
    • Sandoval, K.E.1    Witt, K.A.2
  • 12
    • 79951535418 scopus 로고    scopus 로고
    • Comprehensive Small Animal Imaging Strategies on a Clinical 3T Dedicated Head MR-Scanner; Adapted Methods and Sequence Protocols in CNS Pathologies
    • Pillai DR, Heidemann RM, Kumar P, Shanbhag N, Lanz T, Dittmar MS et al. Comprehensive Small Animal Imaging Strategies on a Clinical 3T Dedicated Head MR-Scanner; Adapted Methods and Sequence Protocols in CNS Pathologies. PLoS One 2011; 6: e16091.
    • (2011) PLoS One , vol.6
    • Pillai, D.R.1    Heidemann, R.M.2    Kumar, P.3    Shanbhag, N.4    Lanz, T.5    Dittmar, M.S.6
  • 13
    • 0030580410 scopus 로고    scopus 로고
    • Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats
    • Belayev L, Busto R, Zhao W, Ginsberg MD. Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats. Brain Res 1996; 739: 88-96.
    • (1996) Brain Res , vol.739 , pp. 88-96
    • Belayev, L.1    Busto, R.2    Zhao, W.3    Ginsberg, M.D.4
  • 14
    • 0034988984 scopus 로고    scopus 로고
    • Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system
    • Zhang Y, Pardridge WM. Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system. Stroke 2001; 32: 1378-1384.
    • (2001) Stroke , vol.32 , pp. 1378-1384
    • Zhang, Y.1    Pardridge, W.M.2
  • 15
    • 26444510219 scopus 로고    scopus 로고
    • Extending reperfusion therapy for acute ischemic stroke: Emerging pharmacological, mechanical, and imaging strategies
    • Molina CA, Saver JL. Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies. Stroke 2005; 36: 2311-2320.
    • (2005) Stroke , vol.36 , pp. 2311-2320
    • Molina, C.A.1    Saver, J.L.2
  • 16
    • 0037975646 scopus 로고    scopus 로고
    • Recommendations for advancing development of acute stroke therapies: Stroke Therapy Academic Industry Roundtable 3
    • Fisher M. Recommendations for advancing development of acute stroke therapies: Stroke Therapy Academic Industry Roundtable 3. Stroke 2003; 34: 1539-1546.
    • (2003) Stroke , vol.34 , pp. 1539-1546
    • Fisher, M.1
  • 17
    • 0029025831 scopus 로고
    • Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity
    • Tombran-Tink J, Shivaram SM, Chader GJ, Johnson LV, Bok D. Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. J Neurosci 1995; 15(Part 1): 4992-5003.
    • (1995) J Neurosci , vol.15 , Issue.PART 1 , pp. 4992-5003
    • Tombran-Tink, J.1    Shivaram, S.M.2    Chader, G.J.3    Johnson, L.V.4    Bok, D.5
  • 18
    • 0029064939 scopus 로고
    • Pigment epithelium-derived factor is a survival factor for cerebellar granule cells in culture
    • Taniwaki T, Becerra SP, Chader GJ, Schwartz JP. Pigment epithelium-derived factor is a survival factor for cerebellar granule cells in culture. J Neurochem 1995; 64: 2509-2517.
    • (1995) J Neurochem , vol.64 , pp. 2509-2517
    • Taniwaki, T.1    Becerra, S.P.2    Chader, G.J.3    Schwartz, J.P.4
  • 19
    • 77649261258 scopus 로고    scopus 로고
    • Adenoviral gene delivery of pigment epithelium-derived factor protects striatal neurons from quinolinic acid-induced excitotoxi-city
    • Sanagi T, Yabe T, Yamada H. Adenoviral gene delivery of pigment epithelium-derived factor protects striatal neurons from quinolinic acid-induced excitotoxi-city. J Neuropathol Exp Neurol 2010; 69: 224-233.
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 224-233
    • Sanagi, T.1    Yabe, T.2    Yamada, H.3
  • 20
    • 0037301050 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor prevents advanced glycation end products-induced monocyte chemoattractant protein-1 production in microvascular endothelial cells by suppressing intracellular reactive oxygen species generation
    • Inagaki Y, Yamagishi S, Okamoto T, Takeuchi M, Amano S. Pigment epithelium-derived factor prevents advanced glycation end products-induced monocyte chemoattractant protein-1 production in microvascular endothelial cells by suppressing intracellular reactive oxygen species generation. Diabetologia 2003; 46: 284-287.
    • (2003) Diabetologia , vol.46 , pp. 284-287
    • Inagaki, Y.1    Yamagishi, S.2    Okamoto, T.3    Takeuchi, M.4    Amano, S.5
  • 22
    • 0032104815 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain
    • Planas AM, Justicia C, Soriano MA, Ferrer I. Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain. Glia 1998; 23: 120-129.
    • (1998) Glia , vol.23 , pp. 120-129
    • Planas, A.M.1    Justicia, C.2    Soriano, M.A.3    Ferrer, I.4
  • 24
    • 0029150526 scopus 로고
    • Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons
    • Mattson MP, Lovell MA, Furukawa K, Markesbery WR. Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J Neurochem 1995; 65: 1740-1751.
    • (1995) J Neurochem , vol.65 , pp. 1740-1751
    • Mattson, M.P.1    Lovell, M.A.2    Furukawa, K.3    Markesbery, W.R.4
  • 25
    • 48749124303 scopus 로고    scopus 로고
    • Gene transfer of PEDF attenuates ischemic brain damage in the rat middle cerebral artery occlusion model
    • Sanagi T, Yabe T, Yamada H. Gene transfer of PEDF attenuates ischemic brain damage in the rat middle cerebral artery occlusion model. J Neurochem 2008; 106: 1841-1854.
    • (2008) J Neurochem , vol.106 , pp. 1841-1854
    • Sanagi, T.1    Yabe, T.2    Yamada, H.3
  • 26
    • 34548125012 scopus 로고    scopus 로고
    • Administration of pigment epithelium-derived factor (PEDF) inhibits cold injury-induced brain edema in mice
    • Jinnouchi Y, Yamagishi S, Matsui T, Takenaka K, Yoshida Y, Nakamura K et al. Administration of pigment epithelium-derived factor (PEDF) inhibits cold injury-induced brain edema in mice. Brain Res 2007; 1167: 92-100.
    • (2007) Brain Res , vol.1167 , pp. 92-100
    • Jinnouchi, Y.1    Yamagishi, S.2    Matsui, T.3    Takenaka, K.4    Yoshida, Y.5    Nakamura, K.6
  • 27
    • 33344463910 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor protects retinal pigment epithelium from oxidant-mediated barrier dysfunction
    • Ho TC, Yang YC, Cheng HC, Wu AC, Chen SL, Tsao YP. Pigment epithelium-derived factor protects retinal pigment epithelium from oxidant-mediated barrier dysfunction. Biochem Biophys Res Commun 2006; 342: 372-378.
    • (2006) Biochem Biophys Res Commun , vol.342 , pp. 372-378
    • Ho, T.C.1    Yang, Y.C.2    Cheng, H.C.3    Wu, A.C.4    Chen, S.L.5    Tsao, Y.P.6
  • 28
    • 0033041270 scopus 로고    scopus 로고
    • Early changes in water diffusion, perfusion, T1, and T2 during focal cerebral ischemia in the rat studied at 8.5T
    • Calamante F, Lythgoe MF, Pell GS, Thomas DL, King MD, Busza AL et al. Early changes in water diffusion, perfusion, T1, and T2 during focal cerebral ischemia in the rat studied at 8.5T. Magn Reson Med 1999; 41: 479-485.
    • (1999) Magn Reson Med , vol.41 , pp. 479-485
    • Calamante, F.1    Lythgoe, M.F.2    Pell, G.S.3    Thomas, D.L.4    King, M.D.5    Busza, A.L.6
  • 30
    • 57649186797 scopus 로고    scopus 로고
    • Post-ischemic brain damage: Pathophysiology and role of inflammatory mediators
    • Amantea D, Nappi G, Bernardi G, Bagetta G, Corasaniti MT. Post-ischemic brain damage: pathophysiology and role of inflammatory mediators. FEBS J 2009; 276: 13-26.
    • (2009) FEBS J , vol.276 , pp. 13-26
    • Amantea, D.1    Nappi, G.2    Bernardi, G.3    Bagetta, G.4    Corasaniti, M.T.5
  • 31
    • 33644893607 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor
    • Zhang SX, Wang JJ, Gao G, Shao C, Mott R, Ma JX. Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor. FASEB J 2006; 20: 323-325.
    • (2006) FASEB J , vol.20 , pp. 323-325
    • Zhang, S.X.1    Wang, J.J.2    Gao, G.3    Shao, C.4    Mott, R.5    Ma, J.X.6
  • 32
    • 0041743159 scopus 로고    scopus 로고
    • VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
    • Sun Y, Jin K, Xie L, Childs J, Mao XO, Logvinova A et al. VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. J Clin Invest 2003; 111: 1843-1851.
    • (2003) J Clin Invest , vol.111 , pp. 1843-1851
    • Sun, Y.1    Jin, K.2    Xie, L.3    Childs, J.4    Mao, X.O.5    Logvinova, A.6
  • 33
    • 0041842763 scopus 로고    scopus 로고
    • Regulation of vascular permeability by vascular endothelial growth factors
    • Bates DO, Harper SJ. Regulation of vascular permeability by vascular endothelial growth factors. Vasc Pharmacol 2002; 39: 225-237.
    • (2002) Vasc Pharmacol , vol.39 , pp. 225-237
    • Bates, D.O.1    Harper, S.J.2
  • 34
    • 2342507629 scopus 로고    scopus 로고
    • Identification of the antivasopermeability effect of pigment epithelium-derived factor and its active site
    • Liu H, Ren JG, Cooper WL, Hawkins CE, Cowan MR, Tong PY. Identification of the antivasopermeability effect of pigment epithelium-derived factor and its active site. Proc Nat Acad Sci USA 2004; 101: 6605-6610.
    • (2004) Proc Nat Acad Sci USA , vol.101 , pp. 6605-6610
    • Liu, H.1    Ren, J.G.2    Cooper, W.L.3    Hawkins, C.E.4    Cowan, M.R.5    Tong, P.Y.6
  • 36
    • 0036173275 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and angiopoietins in focal cerebral ischemia
    • Zhang Z, Chopp M. Vascular endothelial growth factor and angiopoietins in focal cerebral ischemia. Trends Cardiovasc Med 2002; 12: 62-66.
    • (2002) Trends Cardiovasc Med , vol.12 , pp. 62-66
    • Zhang, Z.1    Chopp, M.2
  • 37
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angio-genesis
    • Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angio-genesis. Nature 2011; 473: 298-307.
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 38
    • 0036104828 scopus 로고    scopus 로고
    • Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
    • Volpert OV, Zaichuk T, Zhou W, Reiher F, Ferguson TA, Stuart PM et al. Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 2002; 8: 349-357.
    • (2002) Nat Med , vol.8 , pp. 349-357
    • Volpert, O.V.1    Zaichuk, T.2    Zhou, W.3    Reiher, F.4    Ferguson, T.A.5    Stuart, P.M.6
  • 39
    • 36649003694 scopus 로고    scopus 로고
    • PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells
    • Ho TC, Chen SL, Yang YC, Liao CL, Cheng HC, Tsao YP. PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells. Cardiovasc Res 2007; 76: 213-223.
    • (2007) Cardiovasc Res , vol.76 , pp. 213-223
    • Ho, T.C.1    Chen, S.L.2    Yang, Y.C.3    Liao, C.L.4    Cheng, H.C.5    Tsao, Y.P.6
  • 40
    • 8644244647 scopus 로고    scopus 로고
    • Diffusion of epidermal growth factor in rat brain extracellular space measured by integrative optical imaging
    • Thorne RG, Hrabetova S, Nicholson C. Diffusion of epidermal growth factor in rat brain extracellular space measured by integrative optical imaging. J Neurophysiol 2004; 92: 3471-3481.
    • (2004) J Neurophysiol , vol.92 , pp. 3471-3481
    • Thorne, R.G.1    Hrabetova, S.2    Nicholson, C.3
  • 41
    • 33746804938 scopus 로고    scopus 로고
    • Reactive oxygen species in the cerebral circulation: Are they all bad?
    • Miller AA, Drummond GR, Sobey CG. Reactive oxygen species in the cerebral circulation: are they all bad? Antioxid Redox Signal 2006; 8: 1113-1120.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1113-1120
    • Miller, A.A.1    Drummond, G.R.2    Sobey, C.G.3
  • 42
    • 0032964106 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase cascade is necessary but not sufficient for basic fibroblast growth factor-and epidermal growth factor-stimulated expression of endothelial nitric oxide synthase in ovine fetoplacental artery endothelial cells
    • Zheng J, Bird IM, Melsaether AN, Magness RR. Activation of the mitogen-activated protein kinase cascade is necessary but not sufficient for basic fibroblast growth factor-and epidermal growth factor-stimulated expression of endothelial nitric oxide synthase in ovine fetoplacental artery endothelial cells. Endocrinology 1999; 140: 1399-1407.
    • (1999) Endocrinology , vol.140 , pp. 1399-1407
    • Zheng, J.1    Bird, I.M.2    Melsaether, A.N.3    Magness, R.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.