Early changes in water diffusion, perfusion, T1, and T2 during focal cerebral ischemia in the rat studied at 8.5 T

Magnetic Resonance in Medicine

Volumn 41, Issue 3, 1999, Pages 479-485

  Calamante, Fernando ^a   Lythgoe, Mark F ^a   Pell, Gaby S ^b   Thomas, David L ^a,b   King, Martin D ^a   Busza, Albert L ^a   Sotak, Christopher H ^a,c   Williams, Stephen R ^a   Ordidge, Roger J ^b   Gadian, David G ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Arterial spin tagging; Deoxyhemoglobin; Diffusion tensor trace; Stroke

Indexed keywords

MAGNETIC RESONANCE IMAGING; RATS; TISSUE;

ARTERIAL SPIN; DEOXYHEMOGLOBIN; DIFFUSION TENSOR; FOCAL CEREBRAL ISCHEMIAS; HIGH MAGNETIC FIELDS; MIDDLE CEREBRAL ARTERY OCCLUSIONS; PERFUSION MEASUREMENTS; STROKE;

DIFFUSION IN LIQUIDS;

DEOXYHEMOGLOBIN; WATER;

ANIMAL MODEL; ARTICLE; BODY WATER; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; DATA ANALYSIS; DIFFUSION COEFFICIENT; DISEASE SEVERITY; FLOW KINETICS; MAGNETIC FIELD; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCLUSIVE CEREBROVASCULAR DISEASE; PERFUSION; RAT; SPIN LABELING; STROKE; TISSUE OXYGENATION;

EID: 0033041270     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2594(199903)41:3<479::AID-MRM9>3.0.CO;2-2     Document Type: Article

References (40)

1. Moseley ME, Cohen Y, Mintorovitch J, Chileuitt L, Shimizu H, Kucharczyk J, Wendland MF, Weinstein PR. Early detection of cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectros-copy. Magn Reson Med 1990;14:330-346.
2. van Bruggen N, Roberts TPL, Cremer JE. The application of magnetic resonance imaging to the study of experimental cerebral ischemia. Cerebrovasc Brain Metab Rev 1994;6:180-210.
3. Hoehn-Berlage M. Diffusion-weighted NMR imaging: application to experimental focal cerebral ischemia. NMR Biomed.. 1995;8:345-358.
4. Busza AL, Allen KL, King MD, van Bruggen N, Williams SR, Gadian DG. Diffusion-weighted imaging studies of cerebral ischemia in gerbils. Potential relevance to energy failure. Stroke 1992;23:1602-1612.
5. Kohno K, Hoehn-Berlage M, Mies G, Back T, Hossmann K-A. Relationship between diffusion-weighted MR images, cerebral blood flow, and energy state in experimental brain infarction. Magn Reson Imaging 1995;13:73-80.
6. Ogawa S, Lee TM, Nayak AS, Glynn P. Oxygenation-sensitive contrast in magnetic: resonance image of rodent brain at high magnetic fields. Magn Reson Med 1990;14:68-78.
7. Roussel SA, van Bruggen N, King MD, Gadian DG. Identification of collaterally perfused areas following focal cerebral ischaemia in the rat by comparison of gradient echo and diffusion-weighted MRI.. J Cereb Blood Flow Metab 1995;15:578-586.
8. Knight RA, Ordidge RJ, Helpern JA, Chopp M, Rodolosi LC, Peck D. Tomporal evolution of ischemic damage in rat brain measured by proton nuclear resonance imaging. Stroke 1991;22:802-808.
9. Knight RA, Dereski MO, Holpern JA, Ordidge RJ, Chopp M. Magnetic resonance imaging assessment of evolving focal cerebral ischesnia. Comparison with histopathology in rats. Stroke 1994;25:1252-1262.
10. Helpern JA, Dereski MO, Knight RA, Ordidge RJ, Chopp M, Qing ZX. Histopathological correlations of nuclear magnetic resonance imaging parameters in experimental cerebral ischemia. Magn Reson Imaging 1993;11:241-246.
11. Detre JA, Leigh JS, Williams DS, Koretsky AP. Perfusion imaging. Magn Reson Med 1992;23:37-45.
12. Thulborn KR, Waterton JC, Matthews PW, Radda GK. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim Biophys Acta 1982;714:265-270.
13. Gomori JM, Grossman RI, Yu-Ip C, Asakura T. NMR relaxation times of blood: dependence on field strength, oxidation state, and cell integrity. J Comput Assist Tomogr 1987;11:684-690.
14. Bryant RC, Marill K, Blackmore C, Francis C, Magnetic relaxation in blood and blood clots. Magn Reson Med 1990;13:133-144.
15. Tadamura E, Hatabu H, Li W, Prasad PV, Edelman RR. Effect of oxygen inhalation on relaxation times in various tissues. J Magn Reson Imaging 1997;7:220-225.
16. Lynch LJ. Water relaxation in heterogeneous and biological systems. In: Cohen JS, editor. Magnetic resonance in biology. Vol. 2, New York: John Wiley & Sons: 1983, p 280-286.
17. Ordidge RJ, Helpern JA, Knight RA, Qing Z, Welch KMA. Investigation of cerebral ischemia using magnetization transfer contrast (MTC) MR imaging. Magn Reson Imaging 1991;9:895-902.
18. Zea Longa E, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989;20:84-91.
19. 2 decrease in acute global cerebral ischemia in the gerbil - the contribution of magnetic susceptibility gradients. In: Proceedings of the SMR 2nd Annual Meeting. San Francisco, 1994, p 1389.
20. 1 values by SNAPSHOT-FLASH NMR Imaging. J Magn Reson 1992;96:608-612.
21. Ordidge RJ, Wylezinska M, Hugg JW, Butlerworth E, Franconi F. Frequency offset corrected inversion (FOCI) pulses for use in localized spectroscopy. Magn Reson Med 1996;36:562-566.
22. Mori S, van Zijl PCM. Diffusion weighting by the trace of the diffusion tensor within a single scan. Magn Reson Med 1995;33:41-52.
23. Williams DS, Detre JA, Leigh JS, Koretsky AP. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc Natl Acad Sci USA 1992;89:212-210.
24. Pekar J, Jezzard P, Roberts DA, Leigh JS Jr, Krank JA, McLaughlin AC. Perfusion imaging with compensation for asymmetric magnetization transfer effects. Magn Reson Med 1996;35:70-79.
25. Zhang W, Williams DS, Koretsky AP. Measurements of rat brain perfusion by NMR using spin labeling of arterial water: in vivo determination of the degree of spin labeling. Magn Reson Med 1993;29:416-421.
26. Alsop DC, Detre JA. Reduced transit-time sensitivity in noninvasive magnetic resonance imaging of human cerebral blood flow. J Cereb Blood Flow Metab 1996;16:1236-1249.
27. Herscovitch P, Raichle ME. What is the correct value for the brain-blood partition coefficient for water? J Cereb Blood Flow Metab 1985;5:65-69.
28. Matthews JNS, Altman DG, Campbell MJ, Royston P. Analysis of serial measurements in medical research. BMJ 1990;300:230-255.
29. Ye FQ, Mattay VS, Jezzard P, Frank JA, Weinberger DR, McLaughlin AC. Correction for vascular artifacts in cerebral blood flow values measured by using arterial spin tagging techniques. Magn Reson Med 1997;37:226-235.
30. McLaughlin AC, Ye FQ, Pekar JJ, Santha AKS, Frank JS. Effect of magnetization transfer on the measurement of cerebral blood flow using steady-state arterial spin lagging approaches: a theoretical investigation. Magn Reson Med 1997;37:501-510.
31. Zhang W, Silva AC, Williams DS, Koretsky AP. NMR measurement of perfusion using arterial spin labeling without saturation of macromolecular spins. Magn Reson Mod 1993;33:370-376.
32. Allegrini PR, Hoehn-Berlage M, Busch E, Krüger K, Kerskens CM. NMR imaging observations of rat brain perfusion changes during stroke: interpretation based on combination with physiological parameters. In: Proceedings of the ISMRM 4th Annual Meeting, New York, 1996, p 319.
33. Lythgoe MF, Busza AL, Calamante F, Sotak CH, King MD, Bingham AC, Williams SR, Gadian DG. Effects of diffusion anisotropy on lesion delineation in a rat model of cerebral ischemia. Magn Reson Med 1997;38:662-668.
34. van der Toorn A, Verheul HB, van der Sprenkel JWB, Tulleken CAF, Nicolay K. Changes in metabolites and tissue water status after focal ischemia in cat brain assessed with localized proton MR spectroscopy. Magn Reson Med 1994;32:685-691.
35. Quast MJ, Huang NC, Hillman GR, Kent TA. The evolution of acute stroke recorded by multimodal magnetic resonance imaging. Magn Reson Imaging 1993;11:465-471.
36. Mancuso A, Karibe H, Rooney WD, Zarow GJ, Graham SH, Weiner MW, Weinstein PR. Correlation of early reduction in the apparent diffusion coefficient of water with blood flow reduction during middle cerebral artery occlusion in rats. Magn Reson Med 1995;34:368-377.
37. van Zijl PCM, Eleff SM, Ulatowski JA, Oja JME, Ulug AM, Traystman RJ, Kauppinen RA. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging. Nature Med 1998;4:159-167.
38. Pappata S, Fiorelli M, Rommel T, Hartmann A, Dettmers C, Yamaguchi T, Chabriat H, Poline JB, Crouzel C, Di Giamberardino L, Baron JC. PET study of changes in local brain hemodynamics and oxygen metabolism after unilateral middle cerebral artery occlusion in baboons. J Cereb Blood Flow Metab 1993;13:416-424.
39. Wolff S, Balaban R. Magnetization transfer contrast (MTC) and tissue water proton relaxation in-vivo. Magn Reson Med 1989;10:135-144.
40. Ewing JR, Jiang Q, Boska M, Zhang ZG, Brusca TE, Chopp M, Welch KMA. The forward magnetization transfer rate constant between free and bound proton pools in acute cerebral infarct in the rat. In: Proceedings of the ISMRM 4th Annual Meeting, New York, 1996, p 1662.