메뉴 건너뛰기




Volumn 149, Issue 3, 2011, Pages 225-235

Transport of epidermal growth factor in the stroke-injured brain

Author keywords

Epidermal growth factor; In vivo protein transport; Integrative optical imaging; PEG modification; Protein transport in brain; Stroke

Indexed keywords

EPIDERMAL GROWTH FACTORS; IN-VIVO; INTEGRATIVE OPTICAL IMAGING; PEG MODIFICATION; PROTEIN TRANSPORT IN BRAIN; STROKE;

EID: 79951952167     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.10.022     Document Type: Article
Times cited : (23)

References (60)
  • 1
    • 79951949887 scopus 로고    scopus 로고
    • Stroke and cerebrovascular accidents
    • Stroke and cerebrovascular accidents, World Health Organization, Circulation, 20098 〈http://www.who.int/topics/cerebrovascular-accident/en/ 〉.
    • (2009) Circulation
  • 3
    • 34250790081 scopus 로고    scopus 로고
    • Repairing brain after stroke: A review on post-ischemic neurogenesis
    • DOI 10.1016/j.neuint.2007.04.011, PII S0197018607000939
    • C.Wiltrout, B. Lang, Y.P. Yan,R.J. Dempsey, R. Vemuganti,Repairing brain after stroke: a review on post-ischemic neurogenesis, Neurochem. Int. 50 (2007) 1028-1041. (Pubitemid 46962820)
    • (2007) Neurochemistry International , vol.50 , Issue.7-8 , pp. 1028-1041
    • Wiltrout, C.1    Lang, B.2    Yan, Y.3    Dempsey, R.J.4    Vemuganti, R.5
  • 4
    • 33947288475 scopus 로고    scopus 로고
    • Ischaemic brain damage after stroke: New insights into efficient therapeutic strategies. International Symposium on Neurodegeneration and Neuroprotection
    • DOI 10.1038/sj.embor.7400892, PII 7400892
    • C. Culmsee, J. Krieglstein, Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies - International Symposium on Neurodegeneration and Neuroprotection, EMBO Rep. 8 (2007) 129-133. (Pubitemid 46420838)
    • (2007) EMBO Reports , vol.8 , Issue.2 , pp. 129-133
    • Culmsee, C.1    Krieglstein, J.2
  • 5
    • 34547601983 scopus 로고    scopus 로고
    • Nanomedicine in the diagnosis and therapy of neurodegenerative disorders
    • DOI 10.1016/j.progpolymsci.2007.05.014, PII S0079670007000743, Polymers in Biomedical Applications
    • A.V. Kabanov, H.E. Gendelman, Nanomedicine in the diagnosis and therapy of neuro degenerative disorders, Prog. Polym. Sci. 32 (2007) 1054-1082. (Pubitemid 47198293)
    • (2007) Progress in Polymer Science (Oxford) , vol.32 , Issue.8-9 , pp. 1054-1082
    • Kabanov, A.V.1    Gendelman, H.E.2
  • 7
    • 0034597430 scopus 로고    scopus 로고
    • Vascular niche for adult hippocampal neurogenesis
    • T.D. Palmer, A.R. Willhoite, F.H. Gage, Vascular niche for adult hippocampal neurogenesis, J. Comp. Neurol. 425 (2000) 479-494.
    • (2000) J. Comp. Neurol. , vol.425 , pp. 479-494
    • Palmer, T.D.1    Willhoite, A.R.2    Gage, F.H.3
  • 8
    • 0030586332 scopus 로고    scopus 로고
    • Transport and elimination of recombinant human NGF during long-term delivery to the brain
    • DOI 10.1016/0006-8993(96)00378-2
    • C.E. Krewson, W.M. Saltzman, Transport and elimination of recombinant human NGF during long-term delivery to the brain, Brain Res. 727 (1996) 169-181. (Pubitemid 26246826)
    • (1996) Brain Research , vol.727 , Issue.1-2 , pp. 169-181
    • Krewson, C.E.1    Saltzman, W.M.2
  • 9
    • 0032484235 scopus 로고    scopus 로고
    • NGF release from poly(D,L-lactide-co-glycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability
    • DOI 10.1016/S0168-3659(98)00086-8, PII S0168365998000868
    • J.M. Pean, M.C. Venier-Julienne, F. Boury, P. Menei, B. Denizot, J.P. Benoit, NGF release from poly(D, L-lactide-co-glycolide) microspheres, Effect of some formulation parameters on encapsulated NGF stability, J. Control. Release 56 (1998) 175-187. (Pubitemid 28511138)
    • (1998) Journal of Controlled Release , vol.56 , Issue.1-3 , pp. 175-187
    • Pean, J.-M.1    Venier-Julienne, M.-C.2    Boury, F.3    Menei, P.4    Denizot, B.5    Benoit, J.-P.6
  • 10
    • 34247481332 scopus 로고    scopus 로고
    • Growth factor-stimulated generation of new cortical tissue and functional recovery after stroke damage to themotor cortex of rats
    • B. Kolb, C. Morshead, C. Gonzalez, M. Kim, C. Gregg, T. Shingo, S. Weiss, Growth factor-stimulated generation of new cortical tissue and functional recovery after stroke damage to themotor cortex of rats, J. Cereb. Blood Flow Metab. 27 (2007) 983-997.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 983-997
    • Kolb, B.1    Morshead, C.2    Gonzalez, C.3    Kim, M.4    Gregg, C.5    Shingo, T.6    Weiss, S.7
  • 11
    • 1642365861 scopus 로고    scopus 로고
    • Erythropoietin as a tissue-protective cytokine in brain injury: What do we know and where do we go?
    • G. Grasso, A. Sfacteria, A. Cerami, M. Brines, Erythropoietin as a tissue-protective cytokine in brain injury: what do we know and where do we go? Neuroscientist 10 (2004) 93-98.
    • (2004) Neuroscientist , vol.10 , pp. 93-98
    • Grasso, G.1    Sfacteria, A.2    Cerami, A.3    Brines, M.4
  • 12
    • 34347387938 scopus 로고    scopus 로고
    • Strategies to improve drug delivery across the blood-brain barrier
    • A.G. de Boer, P.J. Gaillard, Strategies to improve drug delivery across the blood-brain barrier, Clin. Pharmacokinet. 46 (2007) 553-576.
    • (2007) Clin. Pharmacokinet. , vol.46 , pp. 553-576
    • De Boer, A.G.1    Gaillard, P.J.2
  • 13
    • 8644244647 scopus 로고    scopus 로고
    • Diffusion of epidermal growth factor in rat brain extracellular space measured by integrative optical imaging
    • DOI 10.1152/jn.00352.2004
    • R.G. Thorne, S. Hrabetova, C. Nicholson, Diffusion of epidermal growth factor in rat brain extracellular space measured by integrative optical imaging, J. Neurophysiol. 92 (2004) 3471-3481. (Pubitemid 39506324)
    • (2004) Journal of Neurophysiology , vol.92 , Issue.6 , pp. 3471-3481
    • Thorne, R.G.1    Hrabetova, S.2    Nicholson, C.3
  • 14
    • 0025771713 scopus 로고
    • Drugs released from polymers - Diffusion and elimination in brain-tissue
    • W.M. Saltzman, M.L. Radomsky, Drugs released from polymers - diffusion and elimination in brain-tissue, Chem. Eng. Sci. 46 (1991) 2429-2444.
    • (1991) Chem. Eng. Sci. , vol.46 , pp. 2429-2444
    • Saltzman, W.M.1    Radomsky, M.L.2
  • 17
    • 0032211606 scopus 로고    scopus 로고
    • Polyethylene glycol-conjugated pharmaceutical proteins
    • DOI 10.1016/S1461-5347(98)00086-8, PII S1461534798000868
    • P. Bailon, W. Berthold, Polyethylene glycol-conjugated pharmaceutical proteins, Pharm. Sci. Technol. Today 1 (1998) 352-356. (Pubitemid 28526964)
    • (1998) Pharmaceutical Science and Technology Today , vol.1 , Issue.8 , pp. 352-356
    • Bailon, P.1    Berthold, W.2
  • 18
    • 27844515221 scopus 로고    scopus 로고
    • PEG-proteins: Reaction engineering and separation issues
    • C.J. Fee, J.A. Van Alstine, PEG-proteins: reaction engineering and separation issues, Chem. Eng. Sci. 61 (2006) 924-939.
    • (2006) Chem. Eng. Sci. , vol.61 , pp. 924-939
    • Fee, C.J.1    Van Alstine, J.A.2
  • 20
    • 78649342665 scopus 로고    scopus 로고
    • Spinal cord blood flow and blood vessel permeability measured by dynamic computed tomography imaging in rats after localized delivery of fibroblast growth factor
    • C.E. Kang, R. Clarkson, C.H. Tator, I.W.T. Yeung, M.S. Shoichet, Spinal cord blood flow and blood vessel permeability measured by dynamic computed tomography imaging in rats after localized delivery of fibroblast growth factor, J. Neurotrauma 27 (2010) 2041-2053.
    • (2010) J. Neurotrauma , vol.27 , pp. 2041-2053
    • Kang, C.E.1    Clarkson, R.2    Tator, C.H.3    Yeung, I.W.T.4    Shoichet, M.S.5
  • 21
    • 0033230001 scopus 로고    scopus 로고
    • Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate
    • N. Belcheva, K. Woodrow-Mumford, M.J. Mahoney, W.M. Saltzman, Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate, Bioconjug. Chem. 10 (1999) 932-937.
    • (1999) Bioconjug. Chem. , vol.10 , pp. 932-937
    • Belcheva, N.1    Woodrow-Mumford, K.2    Mahoney, M.J.3    Saltzman, W.M.4
  • 22
    • 3042796460 scopus 로고    scopus 로고
    • Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion
    • M. Stroh, W.R. Zipfel, R.M. Williams, S.C. Ma, W.W. Webb, W.M. Saltzman, Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion, Nat. Mater. 3 (2004) 489-494.
    • (2004) Nat. Mater. , vol.3 , pp. 489-494
    • Stroh, M.1    Zipfel, W.R.2    Williams, R.M.3    Ma, S.C.4    Webb, W.W.5    Saltzman, W.M.6
  • 23
    • 0037635943 scopus 로고    scopus 로고
    • Diffusion of nerve growth factor in rat striatum as determined by multiphoton microscopy
    • M. Stroh, W.R. Zipfel, R.M. Williams, W.W. Webb, W.M. Saltzman, Diffusion of nerve growth factor in rat striatum as determined by multiphoton microscopy, Biophys. J. 85 (2003) 581-588. (Pubitemid 36753660)
    • (2003) Biophysical Journal , vol.85 , Issue.1 , pp. 581-588
    • Stroh, M.1    Zipfel, W.R.2    Williams, R.M.3    Webb, W.W.4    Saltzman, W.M.5
  • 24
    • 0031963528 scopus 로고    scopus 로고
    • Pathophysiology of acute ischemic stroke: New concepts in cerebral embolism
    • N. Futrell, Pathophysiology of acute ischemic stroke: new concepts in cerebral embolism, Cerebrovasc. Dis. 8 (1998) 2-5.
    • (1998) Cerebrovasc. Dis. , vol.8 , pp. 2-5
    • Futrell, N.1
  • 25
    • 41849103827 scopus 로고    scopus 로고
    • Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery
    • S.C. Cramer, Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery, Ann. Neurol. 63 (2008) 272-287.
    • (2008) Ann. Neurol. , vol.63 , pp. 272-287
    • Cramer, S.C.1
  • 26
    • 4444278918 scopus 로고    scopus 로고
    • Hypoxia-ischemia affects erythropoietin and erythropoietin receptor expression pattern in the neonatal rat brain
    • DOI 10.1016/j.brainres.2004.06.057, PII S000689930401039X
    • E. Spandou, S. Papoutsopoulou, V. Soubasi, G. Karkavelas, C. Simeonidou, G. Kremenopoulos, O. Guiba-Tziampiri, Hypoxia-ischemia affects erythropoietin and erythropoietin receptor expression pattern in the neonatal rat brain, Brain Res. 1021 (2004) 167-172. (Pubitemid 39165793)
    • (2004) Brain Research , vol.1021 , Issue.2 , pp. 167-172
    • Spandou, E.1    Papoutsopoulou, S.2    Soubasi, V.3    Karkavelas, G.4    Simeonidou, C.5    Kremenopoulos, G.6    Guiba-Tziampiri, O.7
  • 28
    • 0035860766 scopus 로고    scopus 로고
    • Crystal structure of human epidermal growth factor and its dimerization
    • H.S. Lu, J.J. Chai, M. Li, B.R. Huang, C.H. He, R.C. Bi, Crystal structure of human epidermal growth factor and its dimerization, J. Biol. Chem. 276 (2001) 34913-34917.
    • (2001) J. Biol. Chem. , vol.276 , pp. 34913-34917
    • Lu, H.S.1    Chai, J.J.2    Li, M.3    Huang, B.R.4    He, C.H.5    Bi, R.C.6
  • 29
    • 0029930911 scopus 로고    scopus 로고
    • In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain
    • C.G. Craig, V. Tropepe, C.M. Morshead, B.A. Reynolds, S. Weiss, D. vanderKooy, In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain, J. Neurosci. 16 (1996) 2649-2658.
    • (1996) J. Neurosci. , vol.16 , pp. 2649-2658
    • Craig, C.G.1    Tropepe, V.2    Morshead, C.M.3    Reynolds, B.A.4    Weiss, S.5    VanderKooy, D.6
  • 30
    • 0030809453 scopus 로고    scopus 로고
    • Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain
    • H.G. Kuhn, J. Winkler, G. Kempermann, L.J. Thal, F.H. Gage, Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain, J. Neurosci. 17 (1997) 5820-5829. (Pubitemid 27310497)
    • (1997) Journal of Neuroscience , vol.17 , Issue.15 , pp. 5820-5829
    • Kuhn, H.G.1    Winkler, J.2    Kempermann, G.3    Thal, L.J.4    Gage, F.H.5
  • 31
    • 0036288833 scopus 로고    scopus 로고
    • Preparation and characterization of mono-PEGylated epidermal growth factor: Evaluation of in vitro biologic activity
    • H. Lee, T.G. Park, Preparation and characterization of mono-PEGylated epidermal growth factor: evaluation of in vitro biologic activity, Pharm. Res. 19 (2002) 845-851, (919).
    • (2002) Pharm. Res. , vol.19
    • Lee, H.1    Park, T.G.2
  • 36
    • 67349222548 scopus 로고    scopus 로고
    • Sensorimotor behavioral effects of endothelin-1 induced small cortical infarcts in C57BL/6 mice
    • K.A. Tennant, T.A. Jones, Sensorimotor behavioral effects of endothelin-1 induced small cortical infarcts in C57BL/6 mice, J. Neurosci. Meth. 181 (2009) 18-26.
    • (2009) J. Neurosci. Meth. , vol.181 , pp. 18-26
    • Tennant, K.A.1    Jones, T.A.2
  • 38
    • 33746068303 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation: An upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury
    • DOI 10.1523/JNEUROSCI.1004-06.2006
    • B. Liu, H.Y. Chen, T.G. Johns, A.H. Neufeld, Epidermal growth factor receptor activation: an upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury, J. Neurosci. 26 (2006) 7532-7540. (Pubitemid 44315222)
    • (2006) Journal of Neuroscience , vol.26 , Issue.28 , pp. 7532-7540
    • Liu, B.1    Chen, H.2    Johns, T.G.3    Neufeld, A.H.4
  • 39
    • 0034946945 scopus 로고    scopus 로고
    • Diffusion and related transport mechanisms in brain tissue
    • DOI 10.1088/0034-4885/64/7/202
    • C. Nicholson, Diffusion and related transport mechanisms in brain tissue, Rep. Prog. Phys. 64 (2001) 815-884. (Pubitemid 32657274)
    • (2001) Reports on Progress in Physics , vol.64 , Issue.7 , pp. 815-884
    • Nicholson, C.1
  • 40
    • 79951954232 scopus 로고
    • An introduction to error analysis - The study of uncertainties in physical measurements - Taylor, Jr
    • B.P. Levitt, An introduction to error analysis - the study of uncertainties in physical measurements - Taylor, Jr, J. Chem. Soc. Faraday Trans. I 79 (1983) 2269.
    • (1983) J. Chem. Soc. Faraday Trans. , vol.79 , pp. 2269
    • Levitt, B.P.1
  • 41
    • 65649152428 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling
    • L. Hammoud, D.E. Burger, X.R. Lu, Q.P. Feng, Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling, Am. J. Physiol. Cell Physiol. 296 (2009) C735-C745.
    • (2009) Am. J. Physiol. Cell Physiol. , vol.296
    • Hammoud, L.1    Burger, D.E.2    Lu, X.R.3    Feng, Q.P.4
  • 42
    • 0004252445 scopus 로고    scopus 로고
    • 3 edPrentice-Hall, Upper Saddle River, New Jersey
    • H.H. Zar, Biostatistical Analysis, 3 edPrentice-Hall, Upper Saddle River, New Jersey, 1996.
    • (1996) Biostatistical Analysis
    • Zar, H.H.1
  • 43
    • 0344420226 scopus 로고    scopus 로고
    • Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates
    • DOI 10.1016/S0169-409X(03)00108-X
    • P. Caliceti, F.M. Veronese, Pharmacokinetic and biodistribution properties of poly (ethylene glycol)-protein conjugates, Adv. Drug Deliv. Rev. 55 (2003) 1261-1277. (Pubitemid 37464561)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.10 , pp. 1261-1277
    • Caliceti, P.1    Veronese, F.M.2
  • 44
    • 0016592056 scopus 로고
    • Characterization of binding of I-125-labeled epidermal growth-factor to human fibroblasts
    • G. Carpenter, K.J. Lembach, M.M. Morrison, S. Cohen, Characterization of binding of I-125-labeled epidermal growth-factor to human fibroblasts, J. Biol. Chem. 250 (1975) 4297-4304.
    • (1975) J. Biol. Chem. , vol.250 , pp. 4297-4304
    • Carpenter, G.1    Lembach, K.J.2    Morrison, M.M.3    Cohen, S.4
  • 45
    • 70450267518 scopus 로고    scopus 로고
    • Plasticity during stroke recovery: From synapse to behaviour
    • T.H. Murphy, D. Corbett, Plasticity during stroke recovery: from synapse to behaviour, Nat. Rev. Neurosci. 10 (2009) 861-872.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 861-872
    • Murphy, T.H.1    Corbett, D.2
  • 46
    • 33748427771 scopus 로고    scopus 로고
    • An analysis of four different methods of producing focal cerebral ischemia with endothelin-1 in the rat
    • V. Windle, A. Szymanska, S. Granter-Button, C. White, R. Buist, J. Peeling, D. Corbett, An analysis of four different methods of producing focal cerebral ischemia with endothelin-1 in the rat, Exp. Neurol. 201 (2006) 324-334.
    • (2006) Exp. Neurol. , vol.201 , pp. 324-334
    • Windle, V.1    Szymanska, A.2    Granter-Button, S.3    White, C.4    Buist, R.5    Peeling, J.6    Corbett, D.7
  • 47
    • 33748365240 scopus 로고    scopus 로고
    • PEGylation of proteins as tailored chemistry for optimized bioconjugates, Polymer Therapeutics I: Polymers as Drugs
    • G. Pasut, F.M. Veronese, PEGylation of proteins as tailored chemistry for optimized bioconjugates, Polymer Therapeutics I: Polymers as Drugs, Conjugates Gene Deliv. Syst. 192 (2006) 95-134.
    • (2006) Conjugates Gene Deliv. Syst. , vol.192 , pp. 95-134
    • Pasut, G.1    Veronese, F.M.2
  • 48
    • 1642445643 scopus 로고    scopus 로고
    • Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
    • V. Tropepe, M. Sibilia, B.G. Ciruna, T. Rossant, E.F. Wagner, D. van der Kooy, Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon, Dev. Biol. 208 (1999) 166-188.
    • (1999) Dev. Biol. , vol.208 , pp. 166-188
    • Tropepe, V.1    Sibilia, M.2    Ciruna, B.G.3    Rossant, T.4    Wagner, E.F.5    Van Der Kooy, D.6
  • 50
    • 23244439227 scopus 로고    scopus 로고
    • Strain variability, injury distribution, and seizure onset in a mouse model of stroke in the immature brain
    • DOI 10.1159/000085984
    • A.M. Comi, M.V. Johnston, M.A. Wilson, Strain variability, injury distribution, and seizure onset in a mouse model of stroke in the immature brain, Dev. Neurosci. 27 (2005) 127-133. (Pubitemid 41096218)
    • (2005) Developmental Neuroscience , vol.27 , Issue.2-4 , pp. 127-133
    • Comi, A.M.1    Johnston, M.V.2    Wilson, M.A.3
  • 51
    • 0035284411 scopus 로고    scopus 로고
    • Peptide and protein PEGylation: A review of problems and solutions
    • DOI 10.1016/S0142-9612(00)00193-9, PII S0142961200001939
    • F.M. Veronese, Peptide and protein PEGylation: a review of problems and solutions, Biomaterials 22 (2001) 405-417. (Pubitemid 32007845)
    • (2001) Biomaterials , vol.22 , Issue.5 , pp. 405-417
    • Veronese, F.M.1
  • 52
    • 35648954720 scopus 로고    scopus 로고
    • Size comparison between proteins PEGylated with branched and linear Poly(Ethylene glycol) molecules
    • C.J. Fee, Size comparison between proteins PEGylated with branched and linear Poly(Ethylene glycol) molecules, Biotechnol. Bioeng. 8 (2007) 725-731.
    • (2007) Biotechnol. Bioeng. , vol.8 , pp. 725-731
    • Fee, C.J.1
  • 53
    • 27544496736 scopus 로고    scopus 로고
    • Protein PEGylation decreases observed target association rates via a dual blocking mechanism
    • S. Kubetzko, C.A. Sarkar, A. Pluckthun, Protein PEGylation decreases observed target association rates via a dual blocking mechanism, Mol. Pharmacol. 68 (2005) 1439-1454.
    • (2005) Mol. Pharmacol. , vol.68 , pp. 1439-1454
    • Kubetzko, S.1    Sarkar, C.A.2    Pluckthun, A.3
  • 54
    • 0001295176 scopus 로고
    • Kinetics of epidermal growth factor/receptor binding on cells measured by total internal reflection/fluorescence recovery after photobleaching
    • E. Hellen, D. Axelrod, Kinetics of epidermal growth factor/receptor binding on cells measured by total internal reflection/fluorescence recovery after photobleaching, J. Fluoresc. 1 (2) (1991) 113-128.
    • (1991) J. Fluoresc. , vol.1 , Issue.2 , pp. 113-128
    • Hellen, E.1    Axelrod, D.2
  • 55
    • 0025240654 scopus 로고
    • Rate constants for binding, dissociation, and internalization of Egf - Effect of receptor occupancy and ligand concentration
    • C.M. Waters, K.C. Oberg, G. Carpenter, K.A. Overholser, Rate constants for binding, dissociation, and internalization of Egf - effect of receptor occupancy and ligand concentration, Biochemistry 29 (1990) 3563-3569.
    • (1990) Biochemistry , vol.29 , pp. 3563-3569
    • Waters, C.M.1    Oberg, K.C.2    Carpenter, G.3    Overholser, K.A.4
  • 56
    • 0023677140 scopus 로고
    • Anomalous binding of epidermal growth-factor to a431 cells is due to the effect of high receptor densities and a saturable endocytic system
    • H.S. Wiley, Anomalous binding of epidermal growth-factor to a431 cells is due to the effect of high receptor densities and a saturable endocytic system, J. Cell Biol. 107 (1988) 801-810.
    • (1988) J. Cell Biol. , vol.107 , pp. 801-810
    • Wiley, H.S.1
  • 57
    • 0021333875 scopus 로고
    • Relationship between epidermal growth-factor receptor occupancy and mitogenic response - Quantitativeanalysis using a steady-state model system
    • D.J. Knauer, H.S. Wiley, D.D. Cunningham, Relationship between epidermal growth-factor receptor occupancy and mitogenic response - quantitativeanalysis using a steady-state model system, J. Biol. Chem. 259 (1984) 5623-5631.
    • (1984) J. Biol. Chem. , vol.259 , pp. 5623-5631
    • Knauer, D.J.1    Wiley, H.S.2    Cunningham, D.D.3
  • 58
    • 0023654775 scopus 로고
    • Binding, internalization, and intracellular processing of protein ligands - Derivation of rate constants by computer modeling
    • A.C. Myers, J.S. Kovach, S. Vukpavlovic, Binding, internalization, and intracellular processing of protein ligands - derivation of rate constants by computer modeling, J. Biol. Chem. 262 (1987) 6494-6499.
    • (1987) J. Biol. Chem. , vol.262 , pp. 6494-6499
    • Myers, A.C.1    Kovach, J.S.2    Vukpavlovic, S.3
  • 59
    • 0020625309 scopus 로고
    • On the mechanisms involved in the regulation of the cell-surface receptors for human choriogonadotropin and mouse epidermal growth factor in cultured Leydig tumor cells
    • C.E. Lloyd, M. Ascoli, On the mechanisms involved in the regulation of the cellsurface receptors for human chorio-gonadotropin and mouse epidermal growth-factor in cultured Leydig tumor-cells, J. Cell Biol. 96 (1983) 521-526. (Pubitemid 13115858)
    • (1983) Journal of Cell Biology , vol.96 , Issue.2 , pp. 521-526
    • Lloyd, C.E.1    Ascoli, M.2
  • 60
    • 0032104815 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain
    • DOI 10.1002/(SICI)1098-1136(199806)23:2<120::AID-GLIA3>3.0.CO;2-A
    • A.M. Planas, C. Justicia, M.A. Soriano, I. Ferrer, Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain, Glia 23 (1998) 120-129. (Pubitemid 28229085)
    • (1998) GLIA , vol.23 , Issue.2 , pp. 120-129
    • Planas, A.M.1    Justicia, C.2    Soriano, M.A.3    Ferrer, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.