Molecular characterization of a novel isolate of Candida tropicalis for enhanced lipid production

Journal of Applied Microbiology

Volumn 114, Issue 5, 2013, Pages 1357-1368

  Dey, P ^a   Maiti, M K ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Candida tropicalis; Lipid production; Nitrogen stress; Oleaginous yeast; Transcriptional regulation of genes

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CANDIDA; CARBON; GENES; METABOLIC ENGINEERING; NITROGEN; SATURATED FATTY ACIDS; SUBSTRATES; YEAST;

CANDIDA TROPICALIS; CARBON SUBSTRATES; FATTY ACIDS PROFILES; LIPID PRODUCTIONS; NITROGEN STRESS; OLEAGINOUS YEASTS; STORAGE LIPIDS; TRANSCRIPTIONAL REGULATION; TRANSCRIPTIONAL REGULATION OF GENE; TROPICALIS;

GLUCOSE;

ACETYL COENZYME A CARBOXYLASE; DIACYLGLYCEROL ACYLTRANSFERASE; FATTY ACID; GLUCOSE; NITROGEN; OLEIC ACID; SATURATED FATTY ACID; XYLOSE;

BIOASSAY; ENZYME ACTIVITY; FATTY ACID; MOLECULAR ANALYSIS; NITROGEN; SUBSTRATE; YEAST;

ARTICLE; BIOMASS; BIOMASS PRODUCTION; CANDIDA TROPICALIS; CARBON SOURCE; FUNGUS CULTURE; FUNGUS ISOLATION; LIPID COMPOSITION; LIPID STORAGE; LIPOGENESIS; NITROSATIVE STRESS; NONHUMAN; TRANSCRIPTION REGULATION; UPREGULATION;

CANDIDA TROPICALIS; THEOBROMA CACAO;

EID: 84876417468     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.12133     Document Type: Article

References (46)

1. Ageitos, M.J., Vallejo, A.J., Veiga-Crespo, P. and Villa, G.T. (2011) Oily yeasts as oleaginous cell factories. Appl Microbiol Biotechnol 90, 1219-1227.
2. Amaretti, A., Raimondia, S., Leonardia, A. and Rossia, M. (2011) Candida freyschussii: an oleaginous yeast producing lipids from glycerol. Chem Eng Trans 27, 139-144.
3. Anderson, B.M. and Ma, D.W.L. (2009) Are all n-3 polyunsaturated fatty acids created equal? Lipids Health Dis 8, 33. doi:10.1186/1476-511X-8-33.
4. Angerbauer, C., Siebenhofer, M., Mittelbach, M. and Guebitz, G.M. (2008) Conversion of sewage sludge into lipids by Lipomyces starkeyi for biodiesel production. Bioresour Technol 99, 3051-3056.
5. Beckman, M. (2006) Cell biology. Great balls of fat. Science 311, 1232-1234.
6. Beopoulos, A., Mrozova, Z., Thevenieau, F., Le Dall, M.T., Hapala, I., Papanikolaou, S., Chardot, T. and Nicaud, J.-M. (2008) Control of lipid accumulation in the yeast Yarrowia lipolytica. Appl Environ Microbiol 74, 7779-7789.
7. Beopoulos, A., Cescut, J., Haddouche, R., Uribelarrea, J.L., Molina-Jouve, C. and Nicaud, J.-M. (2009a) Yarrowia lipolytica as a model for bio-oil production. Prog Lipid Res 48, 375-387.
8. Beopoulos, A., Chardot, T. and Nicaud, J.-M. (2009b) Yarrowia lipolytica: A model and a tool to understand the mechanisms implicated in lipid accumulation. Biochimie 91, 692-696.
9. Beopoulos, A., Nicaud, J.-M. and Gaillardin, C. (2011) An overview of lipid metabolism in yeasts and its impact on biotechnological processes. Appl Microbiol Biotechnol 90, 1193-1206.
10. Branduardi, P., Smeraldi, C. and Porro, D. (2008) Metabolically engineered yeasts: Potential industrial applications. J Mol Microbiol Biotechnol 15, 31-40.
11. Brown, D.A. (2001) Lipid droplets: proteins floating on a pool of fat. Curr Biol 11, 446-449.
12. Dai, C., Tao, J., Xie, F., Dai, Y. and Zhao, M. (2007) Biodiesel generation from oleaginous yeast Rhodotorula glutinis with xylose assimilating capacity. Afr J Biotechnol 6, 2130-2134.
13. Dey, P., Banerjee, J. and Maiti, M.K. (2011) Comparative lipid profiling of two endophytic fungal isolates - Colletotrichum sp. and Alternaria sp. having potential utilities as biodiesel feedstock. Bioresour Technol 102, 5815-5823.
14. Fadaly, H., Naggar, N. and Marwan, E. (2009) Single cell oil production by an oleaginous yeast strain in a low cost cultivation medium. Res J Microbiol 4, 301-313.
15. Fakas, S., Papanikolaou, S., Batsos, A., Galiotou-Panayotou, M., Mallouchos, A. and Aggelis, G. (2009) Evaluating renewable carbon sources as substrates for single cell oil production by Cunninghamella echinulata and Mortierella isabellina. Biomass Bioenergy 33, 573-580.
16. Ferreyra, R.G., Burgardt, N.I., Milikowski, D., Melen, G., Kornblihtt, A.R., Dell' Angelica, E.C., Santome, J.A. and Ermacora, M.R. (2006) A yeast sterol carrier protein with fatty-acid and fatty-acyl-CoA binding activity. Arch Biochem Biophys 453, 197-206.
17. Gatenby, C.M., Orcutt, D.M., Kreeger, D.A., Parker, B.C., Jones, V.A. and Neves, R.J. (2003) Biochemical composition of three algal species proposed as food for captive freshwater mussels. J Appl Phycol 15, 1-11.
18. Gema, H., Kavadia, A., Dimou, D., Tsagou, V., Komaitis, M. and Aggelis, G. (2002) Production of γ-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peel. Appl Microbiol Biotechnol 58, 303-307.
19. Gouda, M.K., Omar, S.H. and Aouad, L.M. (2008) Single cell oil production by Gordonia sp. DG using agro-industrial wastes. World J Microbiol Biotechnol 24, 1703-1711.
20. Hu, C., Zhao, X., Zhao, J., Wu, S. and Zhao, Z.K. (2009) Effects of biomass hydrolysis by-products on oleaginous yeast Rhodosporidium toruloides. Bioresour Technol 100, 4843-4847.
21. Iassonova, D.R., Hammond, E.G. and Beattie, S.E. (2008) Oxidative stability of polyunsaturated triacylglycerols encapsulated in oleaginous yeast. J Am Oil Chem Soc 85, 711-716.
22. Karatay, S.E. and Donmez, G. (2010) Improving the lipid accumulation properties of the yeast cells for biodiesel production using molasses. Bioresour Technol 101, 7988-7990.
23. Kimura, K., Yamaoka, M. and Kamisaka, Y. (2004) Rapid estimation of lipids in oleaginous fungi and yeasts using Nile red fluorescence. J Microbiol Methods 56, 331-338.
24. Li, Q., Du, W. and Liu, D. (2008) Perspectives of microbial oils for biodiesel production. Appl Microbiol Biotechnol 80, 749-756.
25. Liu, H., Zhao, X., Wang, F., Li, Y., Jiang, X., Ye, M., Zhao, Z.K. and Zou, H. (2009) Comparative proteomic analysis of Rhodosporidium toruloides during lipid accumulation. Yeast 26, 553-566.
26. Liu, J., Huang, J., Fan, K.W., Jiang, Y., Zhong, Y., Sun, Z. and Chen, F. (2010) Production potential of Chlorella zofingienesis as a feedstock for biodiesel. Bioresour Technol 101, 8658-8663.
27. Liu, H., Zhao, X., Wang, F., Jiang, X., Zhang, S., Ye, M., Zhao, Z.K. and Zou, H. (2011) The proteome analysis of oleaginous yeast Lipomyces starkeyi. FEMS Yeast Res 11, 42-51.
28. Meng, X., Yang, J., Xu, X., Zhang, L., Nie, Q. and Xian, M. (2009) Biodiesel production from oleaginous microorganisms. Renew Energ 34, 1-5.
29. Morin, N., Cescut, J., Beopoulos, A., Lelandais, G., Le Berre, V., Uribelarrea, J.-L., Molina-Jouve, C. and Nicaud, J. (2011) Transcriptomic analyses during the transition from biomass production to lipid accumulation in the oleaginous yeast Yarrowia lipolytica. PLoS ONE 6, e27966.
30. Ohlrogge, J.B. and Jaworski, J.G. (1997) Regulation of fatty acid synthesis. Ann Rev Plant Physiol Plant Mol Biol 48, 109-136.
31. Pan, L.-X., Yang, D.-F., Shao, L., Li, W., Chen, G.-G. and Liang, Z.-Q. (2009) Isolation of the oleaginous yeast from the soil and studies of their lipid-producing capacities. Food Technol Biotechnol 47, 215-220.
32. Papanikolaou, S. and Aggelis, G. (2002) Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture. Bioresour Technol 82, 43-49.
33. Papanikolaou, S., Sarantou, S., Komaitis, M. and Aggelis, G. (2004) Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media. J Appl Micro biol 97, 867-875.
34. Picataggio, S., Rohrer, T., Deanda, K., Lanning, D., Reynolds, R., Mielenz, J. and Eirich, L.D. (1992) Metabolic engineering of Candida tropicalis for the production of long-chain dicarboxylic acids. Nat Biotechnol 10, 894-898.
35. Ratledge, C. (1991) Microorganisms for lipids. Acta Biotechnol 11, 429-438.
36. Ratledge, C. (2002) Regulation of lipid accumulation in oleaginous microorganisms. Biochem Soc Trans 30, 1047-1050.
37. Ratlege, C. and Tan, K. (1990) Oils and fats: production, degradation and utilization by yeasts. In Yeast Biotechnology and Biocatalysis ed. Verachtert, H. and De Mot, R. pp. 223-254. New York: Marcel Dekker.
38. Rupčic′, J., Blagovic′, B. and Maric′, V. (1996) Cell lipids of the Candida lipolytica yeast grown on methanol. J Chromatogr A 755, 75-80.
39. Steen, E.J., Kang, Y., Bokinsky, G., Hu, Z., Schirmer, A., McClure, A., Del Cardayre, S.B. and Keasling, J.D. (2010) Microbial production of fatty-acid-derived fuels and chemicals from plant biomass. Nature 463, 559-562.
40. Subramaniam, R., Dufreche, S., Zappi, M. and Bajpai, R. (2010) Microbial lipids from renewable resources: production and characterization. J Ind Microbiol Biotechnol 37, 1271-1287.
41. Vicente, G., Bautista, L.F., Rodríguez, R., Gutiérrez, F.J., Sádaba, I., Ruiz-Vázquez, R.M., Torres-Martínez, S. and Garre, V. (2009) Biodiesel production from biomass of an oleaginous fungus. Biochem Eng J 48, 22-27.
42. Wu, S., Hu, C., Jin, G., Zhao, X. and Zhao, Z.K. (2010) Phosphate-limitation mediated lipid production by Rhodosporidium toruloides. Bioresour Technol 101, 6124-6129.
43. Wu, S., Zhao, X., Shen, H., Wang, Q. and Zhao, Z.K. (2011) Microbial lipid production by Rhodosporidium toruloides under sulfate-limited conditions. Bioresour Technol 102, 1803-1807.
44. Wynn, J.P., Hamid, A.A. and Ratledge, C. (1999) The role of malic enzyme in the regulation of lipid accumulation in filamentous fungi. Microbiology 145, 1911-1917.
45. Xue, F.Y., Zhang, X., Luo, H. and Tan, T.W. (2006) A new method for preparing raw material for biodiesel production. Process Biochem 41, 1699-1702.
46. Zhu, L.Y., Zong, M.H. and Wu, H. (2008) Efficient lipid production with Trichosporon fermentans and its use for biodiesel preparation. Bioresour Technol 99, 7881-7885.